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6080405 |
Foam proteins and use thereof
Novel foam proteins, monoclonal antibodies specifically recognizing said proteins, a method for determining foam protein contents in beer samples by an immunoassay using said monoclonal antibodies,...
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6080560 |
Method for producing antibodies in plant cells
A method for producing antibodies in plant cells including the steps of providing a genetic construct that encodes a secretable mammalian single chain antibody, delivering copies of the construct...
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6080840 |
Soluble T cell receptors
An intact, assembled T cell receptor (TcR) in soluble form is provided. The soluble TcR is prepared by splicing the extracellular domains of a T cell receptor to the glycosyl phosphatidylinositol...
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6077519 |
Methods for isolation and use of T cell epitopes eluted from viable cells in vaccines for treating cancer patients
Methods are provided for eluting peptides that are bound to major histocompatibility complex ("MHC") molecules expressed on the cell surfaces of viable cells that have at least one MHC-peptide...
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6074843 |
Polynucleotides encoding human TSC-22 protein homologs
The present invention provides a human TSC-22-like protein (HT22L) and polynucleotides which encode HT22L. The invention also provides expression vectors, host cells, agonists, antisense molecules,...
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6071892 |
Tyrosyl tRNA synthetase polynucleotides
The invention provides tyrS polypeptides and DNA (RNA) encoding tyrS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing tyrS...
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6069296 |
Regulators of G-protein signalling
Disclosed is substantially pure DNA encoding a C. elegans Egl-10 polypeptide; substantially pure Egl-10 polypeptide; methods of obtaining RGS encoding DNA and RGS polypeptides; and methods of using...
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6066781 |
Production of mature proteins in plants
A chimeric gene for use in producing a mature protein in secreted form by stably transformed plant cells is disclosed. The gene includes a DNA coding sequence encoding a fusion protein having an...
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6060277 |
Human AFC1
The hAFC1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing hAFC1 polypeptides and...
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6060284 |
DNA encoding interleukin-B30
Purified genes encoding cytokines from a mammal, reagents related thereto including purified proteins, specific antibodies, and nucleic acids encoding this molecule are provided. Methods of using...
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6054298 |
Fringe proteins and pattern formation
Isolated DNA encoding a protein or polypeptide having at least one biological activity of a vertebrate fringe protein, as well as the protein or polypeptide encoded thereby, are described. Assays...
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6054635 |
Raspberry promoter and methods for expression of transgenes in plants
The present invention is directed to the identification and isolation of a promoter region from a raspberry genome. The promoter is operably linked, in a native raspberry genome, to the coding...
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6054290 |
Human vesicle binding protein
The present invention provides a human vesicle binding protein (MVBP) and polynucleotides which identify and encode MVBP. The invention also provides expression vectors, host cells, agonists,...
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6048715 |
Two-phase partition affinity separation system and affinity separated cell-containing composition
A two-phase partition system is provided for affinity separation of a composition containing a polysaccharide binding peptide from a mixture such as a fermentation broth. The peptide may be from an...
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6048724 |
Method of producing clonal cell strains which express exogenous DNA encoding glucagon-like peptide 1
The present invention relates to transfected primary and secondary somatic cells of vertebrate origin, particularly mammalian origin, transfected with exogenous genetic material (DNA) that encodes...
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6046029 |
Nucleic acids encoding human fatty acid synthase-like protein
The invention provides a human fatty acid synthase-like protein (HFASLP) and polynucleotides which identify and encode HFASLP. The invention also provides expression vectors, host cells,...
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6043085 |
Ehrlichia canis 120-kDa immunodominant antigenic protein and gene
The present invention provides a 120-kDa protein gene of Ehrlichia canis, amplified by PCR using primers derived from the DNA sequences flanking the Ehrlichia chaffeensis 120-kDa protein gene. The...
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6040429 |
Congenital heart disease proteins and products related thereto
In accordance with the present invention, there are provided novel Congenital Heart Disease (CHD) proteins. Nucleic acid sequences encoding such proteins and assays employing same are also...
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6033843 |
Interaction of cyclin D1 and estrogen receptor and its use in assays
The present invention relates to the finding that cyclin D1 interacts with estrogen receptor to provide activation of estrogen responsive genes. The present invention provides in vitro and in vivo...
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6033870 |
Human transmembrane protein
The invention provides a novel human integral membrane protein (TMP-2) and polynucleotides which encode TMP-2. The invention also provides expression vectors, host cells, agonists, antisense...
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6033873 |
Drug binding protein
This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive...
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6031090 |
Molecular cloning of a 7TM receptor (GPR31A)
GPR31A polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing GPR31A polypeptides and...
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6030806 |
Human chromosome 16 genes, compositions, methods of making and using same
In accordance with the present invention, there are provided isolated nucleic acids encoding a human netrin, a human ATP binding cassette transporter, a human ribosomal L3 subtype, and a human...
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6030811 |
Polynucleotides encoding a human mystrophin clone, HSABH01
A human cDNA encoding human myotrophin and the polypeptide encoded thereby and a procedure for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for...
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6020169 |
Production of secreted foreign polypeptides in plant cell culture
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6020158 |
Isolated polynucleotide for novel G-protein coupled receptor
The present invention is directed to an isolated polynucleotide for novel G-Protein Coupled Receptors. More particularly, the present invention provides an isolated polynucleotide comprising the...
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6017729 |
Receptor activator of NF-κB
Isolated receptors, DNAs encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The receptors are...
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6015708 |
Gene manipulation and expression using genomic elements
Expression of mammalian target genes is achieved by employing chromosomal target DNA, either native primary cells or YACs in a yeast host, where the YACs include a fragment of a mammalian...
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6015941 |
Peptide derivatives of tachyplesin having antimicrobial activity
Compositions comprising antimicrobial peptides are provided. The peptides are derivatives of tachyplesin having amino acid substitutions in which the four cysteine residues are replaced with...
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6013472 |
GA4 DNA, protein and methods of use
The invention relates to the DNA and protein encoded by the GA4 locus. This protein is believed to be a member of the family of enzymes involved in the biosynthesis of the gibberellin family (GA)...
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6005081 |
Purification of recombinant human neurotrophins
Methods are provided for large scale purification of neurotrophins, including mature NGF, suitable for clinical use. The methods provide means to separate neurotrophins from various less desirable...
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6001972 |
Splicing variant of the epstein-barr virus-induced G-protein coupled receptor
EBI 3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EBI 3 polypeptides and...
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5998185 |
Silicone rubber foam support structures for immobilization of cells
Resilient openly porous support structures containing silicon are prepared for cell immobilization. A preferred structure is made of porous silicone rubber foam, and cells are adsorbed to the...
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5998163 |
Method for in vitro protein synthesis
A method for performing coupled in vitro transcription and translation reactions is disclosed. In the transcription reaction, the quantity of mRNA produced is limited to a level of less than about...
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5989825 |
Excitatory amino acid transporter gene and uses
This invention relates to novel mammalian excitatory amino acid transporter proteins and genes encoding such proteins. The invention is directed towards the isolation, characterization and use of...
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5989818 |
DNA encoding human RSEC6 related protein
The invention provides a human rSec6 related vesicle transport protein (HSEC6) and polynucleotides which identify and encode HSEC6. The invention also provides expression vectors, host cells,...
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5989820 |
Polynucleotides encoding a human adipophilin protein homolog
The invention provides a human human adipophilin-like protein (HALP) and polynucleotides which identify and encode HALP. The invention also provides expression vectors, host cells, antibodies,...
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5989565 |
Elution and identification of T cell epitopes from viable cells
Methods are provided for eluting peptides that are bound to major histocompatibility complex ("MHC") molecules expressed on the cell surfaces of viable cells that have at least one MHC-peptide...
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5985598 |
TCL-1 gene and protein and related methods and compositions
The present invention relates to nucleotide sequences of TCL-1 genes and amino acid sequences of their encoded proteins, as well as derivatives and analogs thereof, and antibodies thereto. The...
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5985290 |
Purified pancreatic tumor cell lines and related compositions and method
The present invention provides a method of treating cancer comprising (a) obtaining a tumor cell line, (b) modifying the tumor cell line to render it capable of producing an increased level of a...
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5981211 |
Maintaining cells for an extended time by entrapment in a contracted matrix
Methods of maintaining animal cells for product production, for supporting hepatocyte function and viability to treat a patient suffering from hepatic failure and for preserving tissue-specific...
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5981214 |
Production of proteins using homologous recombination
Methods and compositions are provided for expression of mammalian genes in culture. An amplifiable gene is introduced by homologous recombination in juxtaposition to a target gene, the resulting...
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5981836 |
Plant plastid division genes
Disclosed are DNA sequences that play a critical role in regulating plastid division in plants. Also disclosed is a method for obtaining transgenic plants with novel phenotypes, characterized by...
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5976840 |
Polynucleotides encoding gluS polypeptides of streptococcal pneumoniae
The invention provides gluS polypeptides and DNA (RNA) encoding gluS polypetides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing gluS...
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5977434 |
Procedures and materials for conferring disease resistance in plants
The present invention provide nucleic acids encoding polypeptides which confer resistance to Xanthomonas spp. The nucleic acids can be used to produce transgenic plants resistant to the pathogen.
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5977306 |
Parasitic helminth P39 proteins, and uses thereof
The present invention relates to parasitic helminth proteins of about 39 kD (i.e., P39 proteins); to parasitic helminth P39 nucleic acid molecules, including those that encode such proteins; and to...
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5973123 |
Immunoassay for the detection of MIA
The subject matter of the present invention are high-affinity monoclonal antibodies against MIA (Melanoma inhibitory activity) in native conformation, which can be used for the detection of...
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5972177 |
Process for producing protein hydrolysates
The invention relates to a method for producing protein hydrolyzates from animal and/or vegetable starting materials by comminuting the starting materials, mashing the comminuted starting materials...
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5969127 |
3' untranslated regions of α-amylase genes
An expression vector comprising a promoter capable of directing expression of a coding sequence in an angiosperm cell, and a 3' untranslated region of a rice α-amylase gene, wherein, after the...
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5968815 |
Promoter of M. paratuberculosis and its use for the expression of immunogenic sequences
The invention relates to a nucleotide sequence which is present at a position adjacent to the 5' end of the reverse sequence complementary to the open reading frame coding for a potential...
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