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9040252 Method for increasing and regulating light emission from a chemiluminescent reaction  
Method for increasing and regulating the emission of light from a chemiluminescent reaction including luminol, a peroxidase enzyme, an oxidant and an electron mediator (primary enhancer) through...
9040251 Biomolecule fixing board and method of manufacturing the same  
This invention provides a biomolecule modifying substrate comprising biomolecules selectively fixed to given regions thereon. The biomolecule modifying substrate comprises: a substrate at least...
9040308 Sample collection and analysis  
Management of the health status of an animal colony using a plurality of blood collection cards and the analysis of dried blood from members of the colony that has been collected on the cards....
9034661 Method for producing molecule immobilizing substrate, and molecule immobilizing substrate  
There is disclosed a method for producing a molecule immobilizing substrate, comprising at least the steps of: forming, on a substrate, a monomolecular film including hydroxyl groups, cyano...
9029094 Biomechanical-based methods of diagnosing scoliosis  
Methods for diagnosing a scoliosis (e.g., adolescent idiopathic scoliosis (AIS)) and/or a predisposition to developing a scoliosis based on the determination of the variation of osteopontin (OPN)...
9029096 Assay and method  
The present invention relates to a method and assay useful for determining the sensitivity of the cells of a subject to genetic damage from electromagnetic radiation. The assay may comprise a...
9023607 Method for early diagnosis of alzheimer'S disease using phototransistor  
A method for diagnosing Alzheimer's disease by detecting the presence of beta-amyloid in cells using a phototransistor device. Cells that potentially contain beta-amyloid are provided and labeled...
9023841 Compositions and methods for the treatment of asthma and associated disorders  
This disclosure provides methods for treating asthma or an associated disorder in a patient in need thereof, by administering to the patient an effective amount of an autophagy inducing agent,...
9023766 Method and arrays for detecting biological molecules  
Arrays and methods for detecting one or more biological molecules, where the methods generally comprise the steps of: providing a first support structure fixed with one or more reagents; providing...
9017950 Method for enhancing enzyme assays  
Additives capable of controlling the reaction rate between substrate and enzyme to form a dye in enzyme assays with absorbance, chemiluminescence, and fluorescence are effective tools for...
9017958 Method of simultaneous detection of heparin-induced immunoglobulins types G, A, and M  
The invention provides a method for detecting heparin-induced antibodies comprising a) binding a PF4-heparin antigen to a solid surface; b) incubating the bound PF4-heparin with a sample...
9012372 Method and means for identifying substances which inhibit IgE production  
The invention relates to the field of biomedical and pharmacological research, in particular to the area of immunology, allergies and autoimmune diseases. The inventors have shown that SWAP-70 is...
9012240 Hydrogel nanoparticle based immunoassay  
An immunoassay device incorporating porous polymeric capture nanoparticles within either the sample collection vessel or pre-impregnated into a porous substratum within fluid flow path of the...
9012405 Citrullinated fibrin-filaggrin chimeric polypeptide capable of detecting the antibodies generated in rheumatoid arthritis  
The present invention concerns a chimeric polypeptide, capable of detecting the antibodies generated in rheumatoid arthritis, comprising at least two citrulinated peptide subunits: (i) one derived...
9012163 Modular point-of-care devices, systems, and uses thereof  
The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The...
9012162 Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers  
The inventors have proposed a novel panel of human serum protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver...
9012155 Oncofetal antigen/immature laminin receptor antibodies for diagnostic and clinical applications  
The present invention relates to antibodies against Oncofetal Antigen/immature Laminin receptor protein (OFA/iLRP) that can be used singly or in conjunction to detect or treat OFA/iLRP-related...
9005899 Chitin-induced immune response based method for diagnosing allergic asthma in patients  
A method of diagnosing allergic asthma in patients, including the steps of: obtaining from a subject a first sample of peripheral blood immune cells and a second sample of peripheral blood immune...
9005912 Hybridoma cell line for producing antibody for type II collagen  
The present invention provides a hybridoma cell line (DSM ACC3145), wherein the hybridoma cell line produces an antibody which specifically binds to an amino acid sequence of type II collagen...
9005993 ***WITHDRAWN PATENT AS PER THE LATEST USPTO WITHDRAWN LIST***
Analyte detection
 
The present disclosure provides methods and/or kits for detecting an analyte in a sample. Some embodiments provide a method for detecting a non-nucleic acid analyte in a sample using a solid...
8999647 Methods of subclassification of ductal carcinoma in situ of the breast  
Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal...
8999655 Increase of myeloid microvesicles in the cerebrospinal fluid as biomarker of microglia/macrophage activation in neurological disorders  
The present invention relates to a method for the diagnostic and/or prognostic of a neurological disease characterized by an inflammation process in a subject comprising measuring the amount of...
9000134 Reagent and kit for early diagnosis of kidney disease  
The invention provides reagents and methods for diagnosing kidney disease in a human or animal.
8999658 Methods and kits for diagnosing obstructive sleep apnea  
The presently-disclosed subject matter provides methods and kits for diagnosing obstructive sleep apnea (OSA) in a subject, such as a human child, wherein a biological sample is provided from the...
9000131 Antibodies that neutralize botulinum neurotoxins  
This disclosure provides antibodies that specifically bind to and typically neutralize botulinum neurotoxins (e.g., BoNT/A, BoNT/B, BoNT/E, etc.) and the epitopes bound by those antibodies. The...
8999659 Body fluid BIN1 as a marker of cardiac health  
The present disclosure provides methods involving use of BIN1 protein levels in biological fluid of a subject in evaluating cardiac health of the subject. The method provided herein may be used to...
8993227 Cancer prognosis by determining phosphorylation of a Xom polypeptide  
Disclosed are composition and methods for treating development-related disorders. Also disclosed are diagnosis methods, prognosis methods, and drug screening methods.
8993235 Encapsulated reagents and methods of use  
The present invention contemplates use of encapsulated aqueous and non-aqueous reagents, solutions and solvents and their use in laboratory procedures. These encapsulated aqueous or non-aqueous...
8993254 Methods for evaluating risk of mother's milk or food inducing an onset of atopic dermatitis, and mother's milk or food with reduced risk of inducing an onset of atopic dermatitis  
An entity of a Th2 adjuvant activity in mother's milk has been revealed as coenzyme A by HPLC and mass spectrometry. The followings have been found out that: a risk of developing atopic dermatitis...
8986936 Post-translation modified cardiac troponin T as a biomarker of a risk for heart failure  
The present invention relates to methods and kits for the prediction of risk for heart failure using post-translation modified forms of cardiac troponin T as a biomarker.
8987423 MAGE antigen binding proteins  
Antigen binding proteins, such as antibodies, which bind to human MAGE-A3, polynucleotides encoding such antigen binding proteins, and uses and manufacture thereof.
8975034 Maternal biomarkers for gestational diabetes  
Embodiments herein relate to the field of screening tools for fetal/maternal wellness, and, more specifically, to biomarkers for gestational diabetes. In various embodiments, the methods may...
8975087 Longitudinal assay  
Embodiments of the invention include methods for detecting and determining the concentrations of macro and small molecules, including bio-molecules, in a liquid or gaseous sample.
8969256 Solution microarrays and uses thereof  
The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. The present invention...
8969525 Hydroxycholesterol immunoassay  
Provided is a derivative of 22-hydroxycholesterol, 24S-hydroxycholesterol, 25-hydroxycholesterol, 26-hydroxycholesterol or 27-hydroxycholesterol. Also provided is a protein conjugated to the above...
8969653 Extracellular vesicles derived from gram-positive bacteria, and use thereof  
The present application relates to extracellular vesicles (EVs) derived from gram-positive bacteria. In detail, the present application provides animal models of disease using extracellular...
8969099 Microanalysis methods and systems using field effect transistor  
Provided is a microanalysis method and system using a Field Effect Transistor (FET). The microanalysis method includes a channel region having a receptor molecule fixed; forming a nano-particle...
8969024 Compositions and methods comprising binding proteins for adalimumab  
Compositions and methods comprising proteins that bind specifically to adalimumab are disclosed herein. Adalimumab is a monoclonal antibody specific for the cytokine TNF-α and was developed to...
8962581 Methods and kits to identify invasive glioblastoma  
The invention encompasses methods and kits used in the detection of invasive glioblastoma based upon the expression of NHERF-1. The methods and kits also allow prediction of disease outcome as...
8962262 Method of protein extraction from cells  
Methods for producing a protein extract from cells, such as cells containing viral proteins, are provided. In general terms, the methods involve: increasing the pH of the cells to a pH of at least...
8962269 Spinal muscular atrophy diagnostic methods  
The present invention relates to the discovery of the human survival motor-neuron gene or SMD gene, which is a chromosome 5-SMA (Spinal Muscular Atrophy) determining gene. The present invention...
8962814 Interleukin-1α antibodies and methods of use  
Fully human monoclonal Abs includes (i) an antigen-binding variable region that exhibits very high binding affinity for IL-1α and (ii) a constant region that is effective at both activating the...
8962268 Method for determining survival prognosis of patients suffering from non-small cell lung cancer (NSCLC)  
The present invention relates to a method for determining the survival prognosis of patients suffering from non-small cell lung cancer. More specifically, the present invention provides methods...
8962267 Method for predicting the response of non-small cell lung cancer patients to targeted pharmacotherapy  
The present invention relates to a method for determining or predicting the response of a patient diagnosed with non small cell lung cancer to targeted pharmacotherapy. The present invention also...
8961977 Antigenic mimics of discontinuous epitopes of pathogen recognized by broadly neutralizing antibodies  
The present invention relates to an anti-idiotypic polypeptide scaffold that includes two or more peptide sequences that mimic a discontinuous epitope of a pathogen that is recognized by or...
8961968 Human monoclonal antibodies against CD25  
Isolated human monoclonal antibodies which bind to and inhibit human CD25, and related antibody-based compositions and molecules, are disclosed. The human antibodies can be produced by a...
8962264 Non-heating detection method for dermatophyte  
The present invention provides a method of detecting dermatophyte, which does not require a complicated operation such as an enzyme treatment and a heat treatment. The present invention provides a...
8956823 Anti-antibody reagent  
An anti-antibody reagent for use in a competitive or sandwich simplex or multiplex assay, said reagent comprising one or more labeled anti-antibodies for the primary antibodies to be determined in...
8956877 Separation-free assay method  
A separation-free assay including a binding partner, a binding partner labeled with a directly luminescent label, and a nonspecifically binding label able to affect the signal of the unbound...
8956614 BACE1 inhibitory antibodies  
The present invention relates to antibodies with a specificity for BACE1. More specifically, the invention provides monoclonal antibodies that bind to BACE1 and are capable of inhibiting the...