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9012136 Detection of an analyte in a sample  
There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte...
9005887 Detection of an analyte in a sample  
There is provided mechanisms for the detection of an analyte in a sample. The mechanisms utilize at least a first measurement channel comprising a detection reactant corresponding to the analyte...
8916353 Circovirus sequences associated with piglet weight loss disease (PWD)  
The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences,...
8785144 Electric analysis method  
Disclosed is an analysis method comprising the steps of: (a) reacting a substance to be analyzed with at least a specific partner which exhibits a selective interaction with the substance,...
8703417 Enzyme-catalyzed metal deposition for the enhanced detection of analytes of interest  
The invention is directed to enhanced methods for detecting an analyte of interest in situ, by immunoassay, or by hybridization comprising binding an enzyme-labeled conjugate molecule to an...
8679772 Immunoassay  
The invention provides a highly sensitive immunoassay for detection of a biological species. The immunoassay comprises exposing an electrode to an analyte liquid putatively containing the...
8658361 Ultra sensitive method for in situ detection of nucleic acids  
Disclosed is a method for in situ detection of one or more target nucleic acids based on a combination of an in situ hybridization (ISH) assay method and a general ISH signal amplification method....
8652795 Mutant lactate oxidase with increased stability and product, methods and uses involving the same  
The present disclosure relates to a mutant lactate oxidase having increased stability, a nucleic acid encoding the mutant lactate oxidase, an expression vector comprising the nucleic acid, a host...
8642283 Screening assay for agents that alter target of rapamycin activity  
The present invention provides an assay for the identification of agents which can modulate TOR-mediated phosphorylation of substrate proteins. The assays of the invention utilize substrate...
8637257 Molecular targets and compounds, and methods to identify the same, useful in the treatment of bone and joint degenerative diseases  
The present invention relates to methods for identifying agents capable of inhibiting the expression or activity of proteins involved in the processes modulating osteoclastogenesis, which...
8609349 Drug selection for breast cancer therapy using antibody-based arrays  
The present invention provides compositions and methods for detecting the activation states of components of signal transduction pathways in tumor cells. Information on the activation states of...
8530170 Enzyme triggered redox altering chemical elimination (E-trace) immunoassay  
The present invention is directed to electronic methods of detecting target analytes such that upon binding of the target analyte a shift in electrochemical potential is seen. This assay relies on...
8526001 Versatile surface plasmon resonance analyzer with an integral surface plasmon resonance enhanced fluorescence mode  
An instrument for measuring and analyzing surface plasmon resonance on a sensor surface has a polarized light source optically connected to the sensor surface by a plurality of optical elements,...
8497136 Device and method for detecting the presence of hemoglobin in a biological sample  
A device and method for detecting the presence of hemoglobin in a biological sample, more particularly, the presence of blood in a fecal sample as an indicator of upper or lower gastrointestinal...
8450080 Methods of monitoring metabolic pathways  
The present invention provides methods and compositions for monitoring cofactors and metabolites of a metabolic pathway of interest. The subject compositions and methods are particularly suited...
8404459 Antibodies specific for soluble amyloid beta peptide protofibrils and uses thereof  
The invention pertains to a method of measuring Aβ protofibrils in a sample. The method includes the steps of (a) providing a labeled monoclonal antibody or fragment thereof that binds wildtype Aβ...
8368897 Versatile surface plasmon resonance analyzer with an integral surface plasmon resonance enhanced fluorescence mode  
An instrument for measuring and analyzing surface plasmon resonance on a sensor surface has a polarized light source optically connected to the sensor surface by a plurality of optical elements,...
8357494 Anti-clusterin oligoclonal antibodies for diagnosis and prediction of the aggressiveness of tumours, diagnostic method and related kits  
The invention concerns anti-clusterin oligoclonal antibodies able to recognize and bind in a selective and specific way antigenic epitopes of clusterin isoforms to be used in tumors diagnosis and...
8323982 Photoelectrocatalytic fluid analyte sensors and methods of fabricating and using same  
Fluid analyte sensors include a photoelectrocatalytic element that is configured to be exposed to the fluid, if present, and to respond to photoelectrocatalysis of at least one analyte in the...
8309345 Method for detecting an antigen  
Provided is a method for detecting an antigen without use of a labeled-antibody. A support having an antibody and a multi-copper oxidase CueO immobilized thereon is brought into contact with a...
8298835 Proteolytic markers as diagnostic biomarkers for cancer, organ injury and muscle rehabilitation/exercise overtraining  
The present invention identifies biomarkers that are diagnostic of nerve cell injury, organ injury, and/or neuronal disorders. Detection of different biomarkers of the invention are also...
8198036 Method for detecting the presence of hemoglobin in a biological sample  
A device and method for detecting the presence of hemoglobin in a biological sample, more particularly, the presence of blood in a fecal sample as an indicator of upper or lower gastrointestinal...
8198033 Methods and materials for observing apoptosis  
The invention provides methods and materials for observing protein fragments generated during apoptosis in order to observe this process in mammalian cells. Embodiments of the invention can be...
8183005 Pharmaceutical agents for treating HCV infections  
The present inventors examined the inhibitory activity against HCV replicon of myriocin, fumonisin B1, and ceramide trafficking inhibitor HPA-12, which are compounds derived from microorganisms...
8148095 Methods for predicting psychotropic drugs which elicit weight gain  
The atypical antipsychotic drugs (AAPDs) have markedly enhanced the treatment of schizophrenias but their use has been hindered by the major weight gain elicited by some AAPDs. We found that...
8148171 Multiplexed analysis of clinical specimens apparatus and methods  
A method for the multiplexed diagnostic and genetic analysis of enzymes, DNA fragments, antibodies, and other biomolecules comprises the steps of constructing an appropriately labeled beadset,...
8114624 Use of the ornithine transcarbamylase (OTC), as a marker for diagnosing brain damages  
The present invention pertains to the domain of brain diseases, and provides novel markers and methods for diagnosing a brain alteration in an individual, especially in patients suffering from...
8067181 MELKS as modifiers of the Rac pathway and methods of use  
Human MELK genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC,...
8048642 Heme choline esters and uses thereof  
Methods of activating an apo-peroxidase are provided. The methods include the steps of providing a solution comprising an apo-peroxidase and a heme choline ester, hydrolyzing the heme choline...
8043820 Diagnostic methods for the detection of risk of autistic spectrum disorder  
The present invention provides methods of identifying markers indicative of the risk of developing a neurodevelopmental disorder caused in part by antibody- or autoantibody-mediated damage of...
8008034 Reducing optical interference in a fluidic device  
This invention is in the field of medical devices. Specifically, the present invention provides portable medical devices that allow real-time detection of analytes from a biological fluid. The...
8008026 Methods for differentially detecting a multimeric form from a monomeric form of a multimer-forming polypeptide through three-dimensional interactions  
The present invention relates to a method for differentially detecting a multimeric form from a monomeric form of a multimer-forming polypeptide in a biosample, which comprises the steps of: (a)...
8003341 Method of amplifying ATP and use thereof  
The ATP amplification method is a method for amplifying and detecting a very trace amount of exogenous ATP by allowing a fusion protein (PPK-ADK) of a polyphosphate kinase and an adenylate kinase,...
7998697 Endotoxin analysis  
The present invention relates to a method for detecting the presence or non-presence of an endotoxin, characterized in that an OmpT protein is brought into contact with a sample suspected of...
7993850 Method and probes for the detection of a tumor-specific fusion protein  
The invention relates to the detection of fusion proteins. Described are a set of at least a first and a second molecular probe, each probe provided with a dye wherein the dyes together allow...
7993869 Method for detecting gluten  
Provided is a mAb-based method for the detection of T cell stimulatory epitopes known to be involved in CD. The method has many advantages compared to the existing methods for the detection of...
7964370 Analytical strip and detecting method using the same  
An analytical strip and a detecting method using the analytical strip are provided. The analytical strip includes a substrate having a channel thereon. The channel has a first region, a second...
7955866 Labelled silica nanoparticles for immunochromatographic assays  
Labelled silica nanoparticles for immunochromatographic reagent, comprising silica nanoparticles containing a labelled substance.
7939291 Methods for the detection of microbial contaminants  
The invention provides methods and compositions for the detection and/or quantification of a microbial contaminant, for example, a bacterial endotoxin or a glucan, in a sample. In particular, the...
7927815 Protein purification method  
A method for removing contaminant DNA in a sample containing a physiologically active protein, which comprises the following steps: 1) converting the sample containing a physiologically active...
7927819 Method for stabilization of proteins in solution  
The present invention relates to a method for stabilization of analytes in solutions of solubilized body samples. The method comprises the steps of solubilizing the body samples obtained from a...
7910320 Methods compositions and compound assays for inhibiting amyloid-beta protein production  
A method for identifying compounds that inhibit amyloid-beta precursor protein processing in cells, comprising contacting a test compound with a GPCR polypeptide, or fragment thereof, and...
7892842 Procedure for the determination of the activity of the protease which activates factor VII from protein solutions  
The present application relates to procedures for the determination of the activity of the protease which activates factor VII, also known as factor VII activating protease or FSAP. The...
7892757 Immunochemical determination method and determination reagent for cytochrome c  
An immunochemical method for the accurate measurement of the quantity of cytochrome c in a body fluid, in particular, blood, and a kit for the measurement. The quantity of cytochrome c can be...
7838249 Assays for rab5 activity  
Methods of determining intracellular levels of Rab5 activity are disclosed, as well as fusion proteins utilized in such methods and recombinant constructs encoding such fusion proteins. The fusion...
7820402 Immunoassay element  
The immunoassay element for quantitatively analyzing an antigen by determining the change in enzymatic activity of an enzyme-labelled antigen or antibody caused by an immunological reaction. The...
7811776 Use of VEGF-D in the diagnosis of lymphangioleiomyomatosis (LAM) disease  
Described herein are methods of diagnosing lymphangioleiomyomatosis (LAM) that permits differentiating LAM from another lung disorder. Methods of treatment are also provided.
7790398 Method for determining effective parathormone activity in a sample  
Method for determining the active parathyroid hormone content in a sample, wherein the component of parathyroid hormone polypeptide chains which are oxidized at one or more sites near the PTH...
7790400 Delta-9-tetrahydrocannabinol detection method  
The invention provides competitive immunoassay techniques for high sensitivity detection of delta-9-tetrahydro-cannabinol (cannabis; THC) employing a carrier conjugate of an intermediate in the...
7785774 Adjustable molecular motor micropower biosensor and its application  
A regulable molecular motor micropower biosensor comprises: a rotary motor, an optical energy conversion device, a signal molecular output device, a power resource system, a protective layer, a...

Matches 1 - 50 out of 366 1 2 3 4 5 6 7 8 >