|
Match
|
Document |
Document Title |
|
|
7358076 |
Sublancin lantibiotic produced by Bacillus subtilis 168
An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides...
|
|
|
7316910 |
Rapid test for hemolytic streptococcus
A reagent for the detection of an extracellular enzymatically active protein produced by a beta-hemolytic streptococcus bacteria found in a host biological fluid includes a proteinaceous substrate...
|
|
|
7270969 |
Methods of constructing and screening diverse expression libraries
The present invention provides novel methods for producing nucleic acid fragment libraries that express highly diverse peptides or protein domains and, in particular, methods for producing nucleic...
|
|
|
7258992 |
Immunization of dairy cattle with chimeric GapC protein against Streptococcus infection
The recombinant production of Gap4, a chimeric GapC plasmin binding protein comprising the entire amino acid sequence of the Streptococcus dysgalactiae GapC protein in addition to unique amino...
|
|
|
7223534 |
Diffraction-based diagnostic devices
A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the...
|
|
|
7169550 |
Diffraction-based diagnostic devices
A biosensor includes a substrate with a receptive material layer of radiation-absorbing member (RAM)-tagged biomolecules disposed thereon. The receptive material is specific for an analyte of...
|
|
|
7160689 |
Pretreatment instrument of saliva and pretreatment method of saliva
In a pretreatment instrument and a pretreatment method of saliva, used for identification and quantitation of Streptococcus mutans in saliva by the immunochromatographic method utilizing an...
|
|
|
7122194 |
Vaccine compositions comprising Streptococcus pneumoniae polypeptides having selected structural motifs
A vaccine composition is disclosed that comprises polypeptides and fragments of polypeptides containing histidine triad residues or coiled-coil regions, some of which polypeptides or fragments lie...
|
|
|
7091049 |
Enhanced diffraction-based biosensor devices
An enhanced diffraction based biosensor system and method are provided for detecting an analyte of interest in a test medium. The system incorporates at least one additional detection tag substance...
|
|
|
7078061 |
Methods, compositions and kits for biomarker extraction
The present invention is directed to methods for extracting markers from biological samples, and to systems, devices, kits and reagents for use in such methods. The invention is also to methods,...
|
|
|
7056510 |
Streptococcus pneumoniae SP036 polynucleotides, polypeptides, antigens and vaccines
The present invention relates to novel vaccines for the prevention or attenuation of infection by Streptococcus pneunoniae. The invention further relates to isolated nucleic acid molecules...
|
|
|
6979576 |
Methods of use of one step immunochromatographic device for Streptococcus A antigen
A method to determine the presence or absence of Streptococcus Group A antigen in a sample, comprising the following steps: extracting the antigen from the sample in an assay chamber with two or...
|
|
|
6974700 |
Kit for use in predicting refractory periodontal disease
A kit and method of predicting a refractory response in a subject diagnosed as having periodontal disease by measuring serum concentrations of actinomyces antibodies, streptococcal antibodies and...
|
|
|
6936422 |
Polynucleotides and their use for detecting resistance to streptogramin A or to streptogramin B and related compounds
The present invention pertains to polynucleotides derived from staphylococcal genes encoding resistance to streptogramin A or to streptogramin B and chemically related compounds. This invention...
|
|
|
6936259 |
CAMP factor of Streptococcus uberis
The CAMP factor gene of Streptococcus uberis ( S. uberis ) is described, as well as the recombinant production of CAMP factor therefrom. Also disclosed are chimeric CAMP factor constructs,...
|
|
|
6908619 |
Camp factor of streptococcus uberis
The CAMP factor gene of Streptococcus uberis ( S. uberis ) is described, as well as the recombinant production of CAMP factor therefrom. CAMP factors can be used in vaccine compositions for the...
|
|
|
6858439 |
Compositions and methods for separation of moieties on chips
The present invention recognizes that separation of components of a sample facilitate, and are often necessary for, sample analysis. Dielectrophoretic separation provides an efficient, reliable,...
|
|
|
6824997 |
Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies
A process is disclosed for obtaining a C-polysaccharide cell wall antigen containing not more than about 10% protein from Streptococcus pneumoniae bacteria. The antigen thus obtained is...
|
|
|
6815172 |
Methods and compositions for opsonophagocytic assays
Methods and compositions comprising immunoassays for the detection of functional antibodies and the analysis of vaccine efficacy are described. In particular, the present invention provides...
|
|
|
6720160 |
Method for simultaneous detection of multiple microbial antigens in biological specimens from mastitic animals
The present invention involves a method and an immuno-analytical device for the rapid and simultaneous detection of multiple micro-organisms in the biological fluids from milk-producing animals...
|
|
|
6689569 |
Saliva test for detection of food allergy, candidiasis, microflora imbalance, intestinal barrier dysfunction and humoral immunodeficiencies
A method for determining a cause for digestive and immune disorders is disclosed. The method determines the levels of antibodies against normal intestinal microflora and food antigens. It then...
|
|
|
6686170 |
Assay devices with mobile control reagents
The present invention relates to an improved immunoassay device for confirming the validity of a test result showing either the presence or absence of an analyte in a patient sample. In the...
|
|
|
6635484 |
Standard used in diagnostic and/or quantification tests
The present invention relates to a device for diagnosing and/or quantifying antibodies present in a biological fluid from a patient and which are specific for a reaction associated with an...
|
|
|
6632614 |
Method for detecting anti-Streptococcus pyogenes DNase B antibody in a test sample
The gene for Streptococcus pyogenes DNase B has been cloned and vectors incorporating the cloned DNA have been used to transform Escherichia coli , allowing efficient and rapid production of the...
|
|
|
6630355 |
Magnetic focusing immunosensor for the detection of pathogens
A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and...
|
|
|
6592876 |
Pneumococcal genes, portions thereof, expression products therefrom, and uses of such genes, portions and products
PspAs, portions thereof, DNA therefor, and immunological compositions, primers and probes based thereon are disclosed claimed.
|
|
|
6566508 |
Fluorogenic compounds and uses therefor
Disclosed are novel coumarin based fluorogenic compounds useful in assaying for biological activity. Specifically, these fluorogenic compounds exhibit fluorescence at particular wavelengths when...
|
|
|
6410696 |
Cyclosporin immunoassay
A method of measuring the amount of cyclosporin in a sample suspected of containing cyclosporin is disclosed. A method of inactivating interfering cross-reactive material in an assay for measuring...
|
|
|
6399295 |
Use of wicking agent to eliminate wash steps for optical diffraction-based biosensors
The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as...
|
|
|
6312955 |
Streptococcus gordonii strains resistant to fluorodeoxyuridine
The present invention features gram-positive bacteria resistant to 5-fluorodeoxyuridine (FUdR). Such bacteria will preferably be commensal, and will not be resistant to antibiotics. Bacteria...
|
|
|
6235487 |
Method of diagnosing Crohn's disease
A method of diagnosing Crohn's disease is described. The method assays for the presence of an immune response to S. mutans antigens in a sample from a patient.
|
|
|
6194221 |
Hybrid one-step immunochromatographic device and method of use
This invention relates to a lateral flow immunochromatographic assay device with an increased range of sensitivity without an increase in the clearance time or the occurrence of false positive...
|
|
|
6165740 |
Method and device for flow-cytometric microorganism analysis
To reduce the effects of the contaminants in the measurement of microorganisms and the reduction of the time necessary for the measurement. Measurement is performed of the microorganism prior to...
|
|
|
6143577 |
Process and installations for separation of magnetic particles in a fluid for biological analysis, and application of said process
A process for magnetic immunoseparation of cells, in particular bacteria, fetal cells, stock cells of bone marrow and circulating cancerous cells, of the type consisting in affixing the target...
|
|
|
6103480 |
Single blood test for detection of food allergy, candidiasis, microflora imbalance, intestinal barrier dysfunction and humoral immunodeficiencies
A method for determining a cause for digestive and immune disorders is disclosed. The method determines the levels of antibodies against normal intestinal microflora and food antigens. It then...
|
|
|
6030835 |
Methods and composition for identifying group a streptococcus
Methods and compositions are provided for identifying a group A Streptococcus in any of a variety of physiological samples, such as blood, saliva, throat swabs, cerebrospinal fluid, brocheolar...
|
|
|
6027906 |
Penicillin binding protein derivatives and uses thereof
The present invention relates to variants of Penicillin Binding Proteins (PBP), which proteins are involved in bacterial peptidoglycan biosynthesis. Disclosed are also DNA molecules coding for the...
|
|
|
6015681 |
Rapid immunoassay for cariogenic bacteria
An assay method and kit for detecting specific oral cariogenic bacteria, ., mutans streptococci, Lactobacillus sp. and Actinomyces sp., separately or in combination, comprising gathering a sample...
|
|
|
6015662 |
Reagents for use as calibrators and controls
The present invention relates to the use of a reagent that binds specifically to a predetermined ligand, contains one or more antibody constant region epitopes, and is uniform in specificity and...
|
|
|
5955089 |
Strain selection of pneumococcal surface proteins
The present invention relates to vaccine composition(s) comprising at least two PspAs from strains selected from at least one family, the family being defined by PspAs from strains belonging to the...
|
|
|
5939252 |
Detachable-element assay device
An assay device for detection or determination of an analyte in a sample uses either removably attachable components or hinged panels to provide greater flexibility and reduce manufacturing and...
|
|
|
5919640 |
Streptococcus suis adhesin protein and method for producing it
Streptococcus suis is a pathogen causing serious disease in pigs. It may also be infectious to man. The Streptococcus suis adhesin protein is useful in diagnosis and therapy of said bacteria. Also...
|
|
|
5871943 |
Immunoassay comprising a truncated pneumococcal surface protein A (PspA)
A purified pneumococcal surface protein A (PspA) comprises a truncated form of the PspA protein which is immunoprotective and contains the protective epitopes of PspA. The PspA protein is soluble...
|
|
|
5821335 |
Biosynthetic gene murg from streptococcus pneumoniae
The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host...
|
|
|
5707814 |
CD8.sup.+ cell antiviral factor
A protein secreted by peripheral blood mononuclear cells and specifically from CD8 + lymphocytes is purified and characterized here and designated CD8 + cell antiviral factor (CAF). The CAF is...
|
|
|
5688659 |
Streptolysin O peptide antigens and methods for the determination of streptolysin antibodies
SLO peptide antigens are described. These peptide antigens are suitable for the determination of SLO antibodies, as immunogens for the production of antibodies against SLO and as vaccines for the...
|
|
|
5665561 |
Modulators of pneumococcal adherence to pulmonary and vascular cells and diagnostic and therapeutic applications
The present invention relates to compositions and methods for preventing pneumococcal infection. In particular, this invention relates to the identification of the minimum receptor targets of...
|
|
|
5663057 |
Process for rapid and ultrasensitive detection and counting of microorganisms by fluorescence
Process for rapid, ultrasensitive and automatic counting of fluorescent biological cells such as microorganims, carried by a solid support such as a filter. The process includes: scanning a solid...
|
|
|
5620865 |
Medium for detecting Enterococci in a sample
Medium for growing Enterococci so that detection may be obtained within 24 hours.
|
|
|
5604109 |
Method for exposing Group A streptococcal antigens and an improved diagnostic test for the identification of Group A streptococci
The present invention relates to the rapid detection of Group A streptococci in clinical specimens, through the enzymatic digestion by a semi-purified Group C streptococcal phage associated lysin...
|