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7390626 |
Methods and kit for diagnosing tick borne illnesses
ELISA, Western Blot, and a peptide-based ELISA were applied to clinical specimens from patients with clinical symptoms of tick borne diseases, including Lyme disease. Peptides from different...
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7390489 |
Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
The present invention relates to a monoclonal antibody binding specifically to the p60 protein of Listeria monocytogenes , a hybridoma cell producing the monoclonal antibody, a test kit comprising...
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7374905 |
Medium composition, method and device for selectively enhancing the isolation of anaerobic microorganisms contained in a mixed sample with facultative microorganisms
The present invention is directed to a medium, broth or agar, and a method of utilizing the same, in order to isolate and/or identify anaerobes from a mixed sample that contains facultative...
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7374904 |
Products containing quantum of bioparticles and method for production thereof
A method for forming a substantially solid product containing a desired quantum of bioparticle, the method comprising (a) providing a sample of bioparticle in liquid form; (b) selecting a desired...
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7374896 |
GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an...
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7371538 |
Microluminometer chip and method to measure bioluminescence
An integrated microluminometer includes an integrated circuit chip having at least one n-well/p-substrate junction photodetector for converting light received into a photocurrent, and a detector on...
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7368256 |
Antibodies against Stachybotrys chartarum and methods for their use
Antibodies to various fungal antigens are disclosed, including monoclonal antibody 9B4 that selectively binds an antigen of Stachybotrys chartarum spores not found in Stachybotrys chartarum ...
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7358076 |
Sublancin lantibiotic produced by Bacillus subtilis 168
An antimicrobial peptide produced by Bacillus subtilis 168 was isolated and characterized and named sublancin 168. The invention includes DNA encoding for the sublancin 168 peptides and peptides...
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7358062 |
Method for diagnosing atrophic gastritis
The press device for a paper web, such as a calender, contains a flexible moving element ( 1 a ) forming an endless structure, said element forming the shell ( 1 ) of a roll, the press device...
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7354776 |
Method of processing and testing powdered samples using immunochromatographic strip tests
A method and kit for processing and testing powdered samples are provided herein. The powdered sample is combined with a fluid to produce a slurry or liquid suspension, and the slurry is contacted...
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7348161 |
Macrolide efflux genetic assembly
Macrolide resistance associated with macrolide efflux (mef) in Streptococcus pneumoniae has been defined with respect to the genetic structure and dissemination of a novel mefE-containing...
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7341843 |
Botulinum toxin A peptides and methods of predicting and reducing immunoresistance to botulinum toxin therapy
The present invention provides BoNT/A peptides as well as methods of predicting or determining immunoresistance to botulinum toxin therapy in an individual using BoNT/A peptides.
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7335480 |
Enriched antibody for detecting mycobacterial infection, methods of use and diagnostic test employing same
The disclosed technology provides an enriched antibody population, highly specific for an antigen of a surface polysaccharide, from a mycobacterium. In a related embodiment, the antibody is...
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7335477 |
Truncated recombinant major outer membrane protein antigen (r56) of Orientia tsutsugamushi strains Karp, Kato and Gilliam and its use in antibody based detection assays and vaccines
A recombinant, refolded non-fusion polypeptide expressed from a truncated r56 gene of the causative agent of scrub typhus, Orientia tsutsugamushi for the Karp, Kato and Gilliam strains has been...
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7335355 |
Antimicrobial agent
A method of identifying an agent that enhances the anti-microbial activity of cationic anti-microbial peptides by blocking the inhibitory effects of the proteinase/glycosaminoglycan pathway, which...
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7329508 |
Use of ylqF, yqeG, yybQ, and ysxC, essential bacterial genes and polypeptides
Disclosed are genes found in Streptococcus pneumoniae that are essential for survival for a wide range of bacteria. These genes are termed “S-ylqF,” “S-yqeG,” “S-yybQ,” “S-yerL,”...
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7329503 |
Recombinant antigens for the detection of Coxiella burnetii
The invention relates to a method for the detection of prior exposure to Coxiella. burnetii infection by antibody-based assays using recombinant, immunodominant C. burnetii polypeptides. The...
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7329500 |
Moraxella (Branhamella) catarrhalis polypeptides and corresponding DNA fragments
The present invention relates to polypeptides of Moraxella ( Branhamela ) catarrhalis which may be used for prophy-laxis, diagnostic and/or therapy purposes.
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7326557 |
Increasing intracellular NADPH availability in E. coli
A method of increasing cellular NADPH levels by expressing one or more genes that encode a enzyme that causes the production of NADPH. The system can be combined with other enzymes that require...
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7320874 |
Assaying the teichoic acids of gram+ bacteria
The invention relates to a method for assaying the teichoic acids present, most commonly in residual form, in a preparation of Gram+ bacterial antigens. This method requires, first of all, a...
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7319030 |
Non-sporulating Bacillus subtilis having parts of the gene encoding sigma G deleted
A non-sporulating Bacillus subtilis strain, a method for preparing it and its use as a production organism. A method for preparing a biologically prepared product with the non-sporulating...
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7319012 |
Protein arrays and methods and systems for producing the same
Methods of rapidly generating and analyzing a plurality of polypeptides are disclosed. More specifically, libraries and arrays of polypeptides are assayed in order to determine their individual...
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7312090 |
Label-free methods for performing assays using a colorimetric resonant reflectance optical biosensor
Methods are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also relates to optical...
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7303891 |
Method of detecting Lawsonia intracellularis antibodies
The present invention relates to the field of animal health and in particular to Lawsonia intracellularis . In particular, the invention relates to a method of diagnosing Lawsonia intracellularis...
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7291477 |
Method and device for trichomonas detection
A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the...
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7291454 |
Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's disease
Disclosed are transgenic animals and transfected cell lines expressing a protein associated with Alzheimer's Disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. Also...
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7291343 |
Enterococcus antigens and vaccines
A majority of E. faecalis and E. faecium clinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. The Enterococcus ...
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7285424 |
Membrane-based assay devices
A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a self-calibrated magnetic binding assay format (e.g.,...
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7270993 |
Protease deficient Caulobacter host cells
Caulobacter optimized for use in expression of heterologous peptides as part of a hybrid Caulobacter S-layer protein are provided as well as methods for producing such Caulobacter. Caulobacter ...
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7270969 |
Methods of constructing and screening diverse expression libraries
The present invention provides novel methods for producing nucleic acid fragment libraries that express highly diverse peptides or protein domains and, in particular, methods for producing nucleic...
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7264941 |
Surface exposed proteins from Chlamydia pneumoniae
The invention relates to the identification of members of a gene family from the human respiratory pathogen Chlamydia pneumoniae , encoding surface exposed membrane proteins of a size of...
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7262271 |
Synthetic peptide constructs for the diagnosis and treatment of periodontitis associated with Porphyromonas gingivalis
The present invention relates to an oral composition and an immunogenic composition for the suppression of the pathogenic effects of the intra-oral bacterium Porphyromonas gingivalis associated...
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7256009 |
Luminous bacteria and methods for the isolation, identification and quantitation of toxicants
Methods for the isolation and identification of a toxicant in a sample are disclosed. Luminescent biological agents (i.e., bacteria) having sensitivity to a toxicant or an isolatable component in a...
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7241905 |
Dioxin analogues and methods and kits for searching out dioxins-decomposing organisms or enzymes or dioxin-decomposing enzyme genes
The present invention provides a novel dioxin analogue for use in the search for organisms capable of degrading dioxin. The dioxin analogue is represented by the following chemical formula (1) or (2):
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7223534 |
Diffraction-based diagnostic devices
A biosensor includes a substrate with a layer of receptive material disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the...
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7214531 |
Pressure transduced chemical assay and method
An assay system has a chamber that receives a test strip onto which a sample comprising an analyte has been placed. The chamber is in gaseous communication with a piezoelectric material that...
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7214499 |
Pathogenic Escherichia coli associated protein
The present invention provides a polypeptide, called EspA, which is secreted by pathogenic E. coli , such as the enteropathogenic (SPEC) and enterohemorrhagic (EHEC) E. coli . The invention also...
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7208286 |
Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia
Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably...
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7205155 |
Method for the determination of substances using the evanescence field method
This invention relates to a method for the determination of substances using the evanescence field method. A cuvette, a microtiter well, a solution and a kit for application in a method according...
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7195909 |
Measurement and use of molecular interactions
The subject invention pertains to a method for determining the affinity between binding partners, or a property of one of the binding partners dependent on the affinity, comprising the steps of:
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7192721 |
Universal rapid test and method for detection of tuberculosis in multiple host species
A universal test apparatus for detecting tuberculosis (TB) in any of many different species of non-primate mammals is provided. The universal test apparatus includes a test site having a...
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7183119 |
Method for sensitive detection of multiple biological analytes
The present invention relates to a method of detecting biological analytes comprising suspending a target analyte in a suspending solution containing polymeric particles marked with a probe,...
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7183066 |
Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins
The present invention provides a method of determining clostridial toxin activity by (a) contacting with a sample a cell containing a clostridial toxin substrate that includes a donor fluorophore;...
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7179611 |
Mono-specific polyclonal antibodies and methods for detecting Clostridium difficile Toxin A
A method is provided for the purification of Clostridium difficile Toxin A antigen comprising reacting impure Toxin A with immobilized mono-specific polyclonal antibodies. The polyclonal...
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7179609 |
Screening method for gastritis
A screening method for gastritis is provided. The method involves the serological measurement of at least two of the following analytes: H,K-ATPase antibodies, Helicobacter pylori antibodies and...
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7169550 |
Diffraction-based diagnostic devices
A biosensor includes a substrate with a receptive material layer of radiation-absorbing member (RAM)-tagged biomolecules disposed thereon. The receptive material is specific for an analyte of...
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7166425 |
Method for detecting low concentrations of a target bacterium that uses phages to infect target bacterial cells
The invention is directed to a method for detecting low concentrations of bacteria in liquid solution that may or may not be complex liquid solutions. In one embodiment, immunomagnetic separation...
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7163810 |
Method for producing target substance
In a method for producing a target substance by using a microorganism comprising culturing a microorganism having an ability to produce the target substance in a medium to produce and accumulate...
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7148028 |
Methods and means relating to atherosclerosis
The present invention relates to the identification of lipid oxidising antibodies as a key pathogenic factor in atherosclerotic disorders. The presence of such antibodies is a important marker for...
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7148017 |
High sensitivity mechanical resonant sensor
A system and method for detecting mass based on a frequency differential of a resonating micromachined structure, such as a cantilever beam. A high aspect ratio cantilever beam is coated with an...
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