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9040250 Binding interaction of proanthocyanidins with bacteria and bacterial components  
A composition having proanthocyanidin compounds having an average degree of polymerization of at least about 6. A method of administering to an immunosuppressed patient or a patient diagnosed with...
9023606 Vaccine protection assay  
The present invention relates to the field of Serum Bactericidal Activity (SBA) assays for Gram negative bacteria, in particular N. meningitidis. The SBA assay is the most important method for...
9012152 Anti-bacterial peptides and methods of treating diseases using same  
Isolated peptides comprising no more than ten amino acids and having anti-bacterial properties are disclosed. In one embodiment the peptides have a consensus amino acid sequence X1X2X3X4X5,...
9005902 Tuberculosis diagnostic test  
A method of diagnosing in a host infection by or exposure to a mycobacterium which expresses ESAT-6 comprising (i) contacting a population of T cells from the host with one or more peptides or...
9005622 Cell wall components of enterococci and uses thereof  
The present invention relates to enterococcal cell wall components and their uses in the prevention and therapy of bacterial infection.
8993252 Methods for detecting antibody that specifically bind a siderophore receptor polypeptide  
The present invention provides compositions including siderophore receptor polypeptides and porins from gram negative microbes, and preferably, lipopolysaccharide at a concentration of no greater...
8975032 Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria  
The object of the present invention is to provide: a test kit for an antibody titer or an antibody against a periodontal disease-causing bacterium in a blood sample, which enables the testing on a...
8962237 Method of detecting and identifying circulating antigens in human biological samples  
Disclosed herein is a method of detecting and identifying antigens that are shed into human bodily fluids during infection. The disclosed method allows circulating antigens associated with a...
8951741 Diagnosis of Strongylus vulgaris  
Embodiments of the presently-disclosed subject matter provide an isolated polypeptide comprising the sequence of SEQ ID NO: 1, fragments thereof, and/or epitopes thereof. Embodiments of the...
8945827 Serological methods and diagnostic tests for syphilis antibodies  
A non-treponemal diagnostic test for syphilis infection includes initially dissolving cholesterol in an organic solvent and further diluting the dissolved cholesterol in an ethanol solution...
8940496 Method for detecting microorganisms belonging to Mycoplasma pneumoniae and/or Mycoplasma genitalium  
A detection method and a detection kit for rapidly and specifically diagnosing Mycoplasma pneumoniae and/or Mycoplasma genitalium infections are provided. The DnaK of Mycoplasma pneumoniae or...
8932807 High throughput in vitro translation (cell-lysate based) assay for detecting quorum sensing signals  
A cell-lysate extract based assay reagent for detecting quorum sensing signals is generally provided, along with methods of making and using the same. The assay reagent generally includes a...
8921054 Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions  
Methods for aiding in the diagnosis of disorders including, but not limited to, PDDs (Pervasive Development Disorders), Dysautonomic disorders, Parkinson's disease and SIDS (Sudden Infant Death...
8921059 Method and kit for detection of guaiacol-producing bacterium  
Disclosed is a method for detecting guaiacol-producing bacteria in a specimen comprising culturing the specimen or a dilution thereof on a plate of a solid medium for acidophilic bacteria...
8906635 Methods of diagnosing Clostridium difficile infection  
Methods of diagnosing Clostridium difficile infection and compounds used in the methods are provided. The diagnostic methods are specific and sensitive methods for detecting a host cell response...
8906630 Assays for detecting pathogenic respiratory bacteria  
The present invention encompasses methods, assays and kits for the detection of pathogenic bacteria in a patient and for the differential diagnosis of pulmonary diseases associated with pathogenic...
8900818 Recombinant antigen for diagnosis and prevention of murine typhus  
The invention relates to a recombinant immunogenic composition from Rickettsia typhi. The invention also relates to a method for the use of the recombinant proteins in detection and diagnostic...
8900881 Quantitative analyte assay device and method  
The present invention relates to a quantitative assay device and a method for the determination of an analyte, based on a test strip, which contains a porous test membrane allowing for capillary...
8900825 Immunogenic proteins of Leptospira  
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
8900824 High-affinity monoclonal antibodies for botulinum toxin type B  
High affinity antibodies for binding epitopes of BoNT/B and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/B in a sample.
8895257 Proteins used for the diagnosis of lyme borreliosis  
Chimera proteins including: (i) at least one sequence of a VlsE protein of a Borrelia species selected from B. garinii, B. burgdorferi sensu stricto and B. afzelii, and (ii) at least one sequence...
8889363 Method for the detection and identification of a variant C. difficile strain in a sample  
The method for detecting and identifying a variant C. difficile strain in a sample is characterized by the following steps: (a) obtaining a sample of excreta or tissue from a human or animal...
8889375 Hypoglycemic effect enhancer  
A hypoglycemic effect enhancer for enhancing the activity of an α-glucosidase inhibitor, the enhancer comprising at least one kind of bacteria selected from the group consisting of bifidobacteria,...
8883431 Compositions and methods for immunodominant antigens of Mycobacterium tuberculosis  
Contemplated compositions, devices, and methods are drawn to various antigens from the pathogen M. tuberculosis and their use in vaccines, therapeutic agents, and various diagnostic tests. In...
8865422 Method for the diagnosis of tuberculosis  
A method for the diagnosis of a tuberculosis infection caused by Mycobacteria belonging to the Mycobacteria tuberculosis complex group (MTC) in an animal including a human being, which comprises...
8841080 System for determining unprocessed and partially processed neurotoxin type A  
The present invention is concerned with tools for the quality control and safety during manufacture of neurotoxins. In particular, it relates to a method for the determination of the amount of...
8828737 Use of focused light scattering techniques in biological applicationa  
Methods for using focused light scattering techniques for the optical sensing of biological particles suspended in a liquid medium are disclosed. The optical sensing enables one to characterize...
8802389 Identification of toxin-binding protein involved in resistance to Cry1 toxins, and related screening methods  
The subject invention relates in part to the surprising and unexpected discovery that insects that are resistant to Bacillus thuringiensis Cry toxins have measurably altered alkaline phosphatase...
8790880 Cysteine protease Cwp84 (CD2787) as a diagnostic marker for Clostridium difficile  
Accurate and fast detection of the presence of Clostridium difficile (C. difficile) disease is crucial for the proper treatment of patients with C. difficile infection. Present tests detecting the...
8785141 Bacterial toxin adsorbing material, method of removing the toxin by adsorbing, and an adsorber formed by filling the adsorbing material therein  
The invention aims at providing an adsorbent for bacterial toxins, a method for removal of such toxins by adsorption, and an adsorber packed with said adsorbent. Provided are an adsorbent for...
8785148 Method and device for rapid detection of bacterial antibiotic resistance/susceptibility  
Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate...
8778619 Oxidized cardiolipin and uses to detect cardiolipin antibodies  
Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, oxidized cardiolipins, which may...
8779088 Vaccine for the treatment of Mycobacterium related disorders  
The invention relates to genes and proteins involved in the sporulation of Mycobacteria and the use thereof in the technical fields of immunology and medicine. A vaccine comprising spore forming...
8771967 Immunomodulation of functional T cell assays for diagnosis of infectious or autoimmune disorders  
Improved assays for detecting the presence of a specific cell-mediated immune response in an individual are provided, where a sample comprising T cells and other cells of the immune system,...
8765393 Endotoxin-binding ligands and their use  
An affinity ligand-matrix conjugate of the structure Z-Spacer-[NX-A]m-NY-A-NK2 is useful for the isolation, separation, purification, characterization, identification or quantification of...
8758772 Peptides and methods for the detection of lyme disease antibodies  
The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences...
8753831 Methods for detection of botulinum neurotoxin  
Provided herein is a large immuno-sorbent surface area assay (ALISSA) for the rapid and sensitive detection of botulinum neurotoxins (BoNTs) and anthrax toxin. This assay is designed to capture a...
8741588 Monoclonal antibodies against PBP2A derived from MRSA and methods of use  
Mouse monoclonal antibodies specifically recognizing the Penicillin Binding Protein 2a (PBP2a) derived from a strain of Methicillin-Resistant Staphylococcus aureus (MRSA) were produced and...
8735554 Reagents, methods, and systems for detecting methicillin-resistant Staphylococcus  
The present invention provides PBP2a peptide antigens for generating antibodies against MRSA, and provides high-affinity binding agents that detect MRSA by selective immunoreactivity with PBP2a....
8728746 Salmonella selective enrichment medium containing tetrathionate and magnesium salt  
The invention relates to a salmonella selective enrichment medium containing tetrathionate or a salt thereof and at least one type of magnesium salt and to a method for detecting salmonella in a...
8728743 Microorganisms having intestinal cell surface glycosylation modulating action  
The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for...
8722347 Optoelectronic sensor  
A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where...
8715949 Applications of the binding interaction of proanthocyanidins with bacteria and bacterial components  
A composition having: a proanthocyanidin; and a macromolecule, an assembly of macromolecules, a semi-solid, or a solid surface to which the proanthocyanidin is immobilized.
8709791 Detection of bioagents using a shear horizontal surface acoustic wave biosensor  
A biosensor combining the sensitivity of surface acoustic waves (SAW) generated at a frequency of 325 MHz with the specificity provided by antibodies and other ligands for the detection of viral...
8709712 Method for identifying bacteria in a sample  
This invention describes a method for identifying bacteria. In particular, this invention relates to a method for identifying and quantifying mycobacteria from a sputum sample taken from a subject...
8709746 Reaction medium for detecting and/or identifying bacteria of the Legionella genus  
A reaction medium for the culture and/or detection and/or identification of bacteria of the Legionella genus includes at least one siliceous compound, where the siliceous compound is a nonpolar...
8703436 Identification of Porphyromonas gingivalis virulence polynucleotides for diagnosis, treatment, and monitoring of periodontal diseases  
The invention provides compositions and methods for the detection of Porphyromonas gingivalis and for the treatment and prevention of diseases and infections caused by P. gingivalis.
8697374 Antibodies to Clostridium difficile spores and uses thereof  
The present invention provides antibodies that bind to the endospore of the bacterium Clostridium difficile, methods of making such antibodies, and methods of using such antibodies, including...
8697375 In vivo biofilm infection diagnosis and treatment  
The present invention relates to a method for in vivo detection of a biofilm infection residing in a mammal, the method comprising (i) administering to the mammal a diagnostic-effective amount of...
8691950 Treponema pallidum triplet antigen  
A Treponema pallidum triplet antigen construct is disclosed which includes three Treponema pallidum antigens (TP15, TP17, and TP47), as well as a ten amino acid leader sequence (tag 261) and human...