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8163275 |
Multi-lineage progenitor cells
Fetal blood multi-lineage progenitor cells that are capable of a wide spectrum of transdifferentiation are described.
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8158079 |
Panel for analysis and analyzer using the same
Provided is a panel (3) for analysis having a chamber inside for transferring a sample liquid dispensed as a drop on an injection port (14). The injection port (14) is formed to protrude in a...
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8137975 |
Method for a rapid antibody-based analysis of platelet populations
A method for identifying a platelet population, preferably a population of immature, reticulated platelets, in a biological sample involves incubating the biological sample for less than 5 minutes...
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8105793 |
Process for in vivo treatment of specific biological targets in bodily fluids
A process for treating biological targets in a fluid of a biological organism, including introducing a fluid comprising a biological target to an assembly comprising an inlet connected to receive...
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8084223 |
Detection of false results in assays
Methods and reagents are disclosed for detecting a false result in an assay for determining a concentration of an analyte in a whole blood sample suspected of containing the analyte. The method...
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8076095 |
Method for enumeration of mammalian micronucleated erythrocyte populations, while distinguishing platelets and/or platelet-associated aggregates
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody...
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8062860 |
Kit for measuring in vivo mutation frequency at an endogenous gene locus
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
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8058073 |
Immunodiagnostic test cards having indicating indicia
An immunodiagnostic test card includes a plurality of transparent chambers wherein each chamber includes a quantity of testing material that combines with a patient sample, when mixed, to produce...
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8048983 |
HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
The present invention provides a conjugate which contains a therapeutic moiety linked to a homing molecule that selectively homes to tumor blood vessels and tumor cells and that specifically binds...
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8008022 |
Methods and kit for detecting breast cancer
The present inventions relates to kits and methods for diagnosing and monitoring breast cancer. An increase in the level or activity of proteins of the ubiquitin/proteasome pathway, and ancillary...
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8008029 |
Method and device for characterizing cellular components of a biological fluid
The invention concerns a method for differentiating and counting cellular components present in a biological fluid sample comprising a primary cytological analysis step typically implemented by a...
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7943368 |
Reducing time to result for blood bank diagnostic testing
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
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7923210 |
Methods to measure immunosuppressive tacrolimus, sirolimus, and cyclosporin a complexes in a blood sample
The present invention provides methods, diagnostic assays, and diagnostic kits based on said methods, to determine levels of immunosuppressive complexes containing immunosuppressive drugs...
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7919266 |
Method of detecting red cell antigen-antibody reactions
A process for the detection of antibodies in a test sample by preparing a suspension of erythrocytes with a test serum or plasma by mixing a test serum or plasma with erythrocytes; incubating the...
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7919265 |
Antibody-based method for isolating Th1 and Th2 helper lymphocytes from human peripheral blood
A negative isolation method for separately isolating preparations of Th1 and Th2 helper lymphocytes from peripheral blood mononuclear cells involving the use of novel combinations of monoclonal...
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7907769 |
Image-based methods for measuring global nuclear patterns as epigenetic markers of cell differentiation
The invention provides methods for determining the differentiation state of cells. The methods include non-invasive, non-perturbing, automatable, and quantitative methods of analysis of cell...
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7897328 |
Blood group antigens of different types for diagnostic and therapeutic applications
The present invention provides compositions and methods for treating or preventing antibody mediated graft rejection and blood typing.
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7888053 |
Making encoded ghost cells for multiplexed detection of anti-red cell alloantibodies
Disclosed are methods for detecting antibody in a sample, where the antibody targets an antigen expressed by red blood cells or red blood cell ghosts. Rather than detecting the binding events...
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7879569 |
Methods for diagnosis of myelodysplastic syndromes (MDS)
The present invention relates to methods and kits for diagnosing, ascertaining the clinical course a of myelodysplastic syndrome(MDS) and ascertaining response to a therapy regimen of...
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7868144 |
Method for unspecific enrichment of bacterial cells
The present invention relates to a method for unspecific enrichment of bacterial cells by means of cationic or anionic polymers and magnetic carriers.
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7867447 |
Method for enumeration of mammalian micronucleated erythrocyte populations, while distinguishing platelets and/or platelet-associated aggregates
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody...
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7858757 |
Monoclonal antibodies with specificity for fetal erythroid cells
The present invention concerns a monoclonal antibody and corresponding hybridoma cells and antigens suitable for isolating fetal cells from maternal blood. The monoclonal antibody reacts with a...
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7824873 |
Blood test kit
A blood crossmatching apparatus, kit and methods for testing the compatibility of mammals for blood transfusion. Particulate layers in the apparatus allow nonagglutinated red blood cells to...
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7824874 |
Method for measuring in vivo mutation frequency at an endogenous gene locus
The present invention relates a method for the enumeration of in vivo gene mutation. The method utilizes differential staining of GPI-anchor deficient erythrocyte populations to distinguish between...
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7811749 |
Measuring free choline to determine suitability of erythrocytes for transfusion
A method of assessing whether or not erythrocytes are suitable for transfusion into a recipient comprising (i) assaying a sample of erythrocytes for free choline, and (ii) comparing the level of...
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7803523 |
Whole blood preparation for cytometric analysis of cell signaling pathways
This invention is directed to a method for preparation of a biological sample for measurement of protein epitopes that allows for the preservation of intracellular protein epitopes and detection of...
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7794720 |
Isolated plasma and method for hyperimmunisation and plasma collection
The present invention relates to isolated canine animal plasma, a method for isolating canine animal plasma, plasma obtained form an immunised or hyperimmunised canine animal and treating a canine...
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7785898 |
Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
The present invention provides methods for identifying and/or enriching fetal cells from maternal blood, using as fetal cell markers the antibodies that the mother produces against paternally...
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7776559 |
Disposable blood test device
A disposable blood test device comprises a substrate configured for carrying a chemical reagent and circuitry formed on the substrate. The circuitry comprises a sensor portion associated with the...
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7771660 |
Electrophoretic interactive spectral methods and devices for the detection and/or characterization of biological particles
Methods for identifying a biological particle in a sample medium include generating an Electrophoretic Quasi-elastic Light Scattering (EQELS) spectrum for the biological particle in the sample...
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7767436 |
Reducing time to result for blood bank diagnostic testing
Methods for reducing time to result in blood bank diagnostic testing with an agitation device and a low ionic strength solution are disclosed. Specifically provided are methods for reducing...
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7754155 |
Devices and methods for isolating target cells
A cell isolating device and method is provided to concentrate or isolate cells with specific characteristics from a mixture of different cell types. One embodiment may comprise two subtypes of...
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7713688 |
Methods and compositions for depleting specific cell populations from blood tissues
The invention provides compositions and methods for cell separation. These reagents and techniques specifically agglutinate cells via surface antigen recognition and can be used to recover even...
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7709219 |
Compositions and methods for detection of antibody binding to cells
The invention includes Rh(D) binding proteins, including antibodies, and DNA encoding such proteins. Methods of generating such proteins and DNAs are also included.
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7670596 |
Multi-lineage progenitor cells
Fetal blood multi-lineage progenitor cells that are capable of a wide spectrum of transdifferentiation are described.
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7651838 |
Prenatal diagnosis method on isolated foetal cell of maternal blood
The invention concerns a novel non-invasive prenatal diagnostic method implemented with a sample of maternal blood. Said method enables prenatal diagnosis on isolated non-apoptotic epithelial...
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7638290 |
Reagent and process for the identification and counting of biological cells
The invention relates to a reagent and a process for the identification and counting of biological cells in a sample. This reagent comprises a cell lysing agent selected from at least one detergent...
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7629165 |
Diagnostic device and method
A method of separating a cell-containing sample into a substantially cell-depleted portion, and a cell-containing portion comprising at least one of a stem cell, a lymphocyte, and a leukocyte...
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7618587 |
Analyzers and methods of analyzing blood
Analyzers and methods of analysis are described for performing blood cell counting and immunoassay on a whole blood specimen in one measurement section. An assay sample is prepared by blending...
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7618792 |
Multiplexed detection of anti-red cell alloantibodies
Disclosed are methods for detecting antibody in a sample, where the antibody targets an antigen expressed by red blood cells or red blood cell ghosts. Rather than detecting the binding events...
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7547554 |
Method and device for the detection of very small quantities of particles
The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a...
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7544513 |
Hemoglobin assay for neonatal screening
The present invention provides an assay, suitable for neonatal screening of hemoglobinopathies by quantitatively determining the presence of at least one pair of hemoglobin (Hb) variants,...
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7527978 |
Flow cytometry based micronucleus assays and kits
The invention is a method for analyzing immature reticulocytes for the presence of micronuclei. The method includes reticulocyte enrichment, fluorescent labeling, micronuclei staining, and analysis...
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7524641 |
Method of separating cells from a sample
Rare cells are separated from a sample fluid by a positive selection or negative selection antibody by centrifuging in a tube containing a harvesting float. The harvesting float has an axial...
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7491504 |
Method for detecting ovarian cancer
A method of detecting ovarian cancer in a female test subject comprising determining the amount of plasmenyl-PA or a biomarker having a mass charge ratio of approximately 655.3 in a sample of a...
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7485433 |
Determination and quantification of red blood cell populations in samples
The invention relates to the detection and determination of erythrocytopathies and hemoglobinopathies. The invention provides a method for distinguishing between subsets of red blood cells in a...
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7449329 |
Blood test kit
A blood crossmatching apparatus, kit and methods for testing the compatibility of mammals for blood transfusion. Particulate layers in the apparatus allow nonagglutinated red blood cells to...
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7429647 |
Polypeptides capable of forming antigen binding structures with specificity for the Rhesus D antigens, the DNA encoding them and the process for their preparation and use
Polypeptides capable of forming antigen binding structures specific for Rhesus D antigens include the sequences indicated in the FIGS. 1a to 16b. The obtained polypeptides, being Fab fragments, MAY...
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7428200 |
Method for triggering through disc grooves and related optical analysis discs and system
An optical analysis disc includes grooves defining corresponding laser-readable tracks and trigger marks that identify respective target regions on the disc. The trigger marks are implemented as a...
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7425421 |
Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody...
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