|
Match
|
Document |
Document Title |
|
|
7588904 |
Perinucleolar compartment as a cancer marker
The present invention relates to compositions and methods for cancer diagnostics, prognostics and predictions, including but not limited to, cancer markers. In particular, the present invention...
|
|
|
7589175 |
Human OX2 receptors
Isolated receptors, nucleic acids encoding such receptors, and pharmaceutical compositions made therefrom, are disclosed. The isolated receptors can be used to regulate an immune response. The...
|
|
|
7588906 |
Hydrogels for biomolecule analysis and corresponding method to analyze biomolecules
Polyacrylamide-based methods of fabricating surface-bound peptide and protein arrays, the arrays themselves, and a method of using the arrays to detect biomolecules and to measure their...
|
|
|
7585637 |
Estrogen related receptor, ERRα, a regulator of bone formation
Methods and pharmaceutical compositions are provided for modulating bone formation in a mammal. Methods are also provided for screening compounds for their efficacy as modulators of bone formation.
|
|
|
7585635 |
Method for detecting and analyzing protein interactions in vivo
Described are various methods of detecting and analyzing protein interactions in a cell. The specific protein interaction is detected by a permanent signal generated by a recombinase activity or...
|
|
|
7585624 |
Detection of the energy of photons from biological assays
A cryogenic detector is used for detection in a biological assay.
|
|
|
7585634 |
Method of predicting risk of lung cancer recurrence, and a composition, kit and microarray for the same
Provided is a method of predicting risk of lung cancer recurrence in a lung cancer patient or after a patient has lung cancer treatment, the method including: obtaining a biological sample from a...
|
|
|
7585674 |
Host microorganisms
A microorganism wherein one or more genes selected from the group of genes participating in sporulation in the middle to late stages of sporulation have been deleted or inactivated; and a process...
|
|
|
7587281 |
Mapping and reconstitution of a conformational discontinuous binding surface
The structure of conformational, discontinuous binding surfaces that associate with a binding molecule, preferably the epitopes of monoclonal antibodies (mAbs) may be discovered. The binding...
|
|
|
7585640 |
Diagnosing and monitoring inflammatory diseases by measuring complement components on white blood cells
The invention is related to methods of diagnosing inflammatory diseases or conditions by determining levels of components of the complement pathway on the surface of white blood cells.
|
|
|
7585636 |
Protein subcellular localization assays using split fluorescent proteins
The invention provides protein subcellular localization assays using split fluorescent protein systems. The assays are conducted in living cells, do not require fixation and washing steps inherent...
|
|
|
7585638 |
Test system for measuring the interaction of STAT 6 with NCoA-1
The present invention relates to a method to identify substances and a use of such substances which can modulate IL-4 dependent signaling involved in tumor diseases, preferably Hodgkin Lymphomas or...
|
|
|
7585941 |
Mu opioid receptor splice variant polypeptides, polynucleotides and methods of screening compositions
The present invention encompasses novel splice variant forms of the mu-opioid receptor-1 (MOR-1) and the polynucleotide sequences encoding the MOR-1 splice variants. The invention further...
|
|
|
7585620 |
Method for identifying and for extracting endotoxin
The invention relates to a method for identifying endotoxins for eliminating said endotoxins from a sample, with the aid of bacteriophage tail proteins.
|
|
|
7582485 |
Method and device for detecting ammonia odors and helicobacter pylori urease infection
The invention provides a breath testing device which visually indicates the presence of ammonia in a patient's breath, in particular ammonia from helicobacter pylori urease infection. The breath...
|
|
|
7582416 |
Ligand for G-protein coupled receptor FPRL2 and uses thereof
The present invention relates to methods, reagents and kits for detecting of formyl peptide receptor like-2 (FPRL2) polypeptide activity in a sample and identifying agents which modulate...
|
|
|
7582437 |
Adaptor protein that binds to mammalian toll-like receptor 3, and gene thereof
A novel adaptor protein and its gene are provided. The novel adaptor protein has a property of binding to mammalian Toll-like receptor 3, which controls type I interferon production that is...
|
|
|
7582443 |
Method for the detection and measurement of Hapten-conjugated biological binding entities by western and dot-blot using anti-hapten antibodies
The invention is a procedure for measuring the binding of an entity (ligand) to a surface by using a hapten-conjugated version of the ligand (hapten-ligand). An excess of the hapten-ligand is...
|
|
|
7582432 |
Dark quenchers for donor-acceptor energy transfer
The present invention provides a family of dark quenchers, termed Black Hole Quenchers (“BHQs”), that are efficient quenchers of excited state energy but which are themselves substantially...
|
|
|
7582296 |
Anti-idiotypic antibodies against factor VIII inhibitor and uses thereof
The present invention discloses anti-idiotypic antibodies and fragments thereof against inhibitory Factor VIII anti-bodies, said inhibitory antibodies having an affinity for the C2 domain of Factor...
|
|
|
7582439 |
Therapeutic molecules
The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present...
|
|
|
7582260 |
Zwitterionic dyes for labeling in proteomic and other biological analyses
The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and...
|
|
|
7582438 |
EphB receptor-binding peptides
The application is related to the identification of peptides that selectively bind to Eph receptors of the B class. Also disclosed are uses of such peptides in the treatment of a variety of...
|
|
|
7582440 |
Imaging, diagnosis and treatment of disease
The present invention relates to endothelial cell-specific genes and encoded polypeptides and materials and uses thereof in the imaging, diagnosis and treatment of conditions involving the vascular...
|
|
|
7579445 |
Reagents and methods for inducing an immune response to prostate specific antigen
The invention is an apparatus and method for the treatment of prostate cancer, and involves administering an antibody that specifically binds with prostate antigen.
|
|
|
7579157 |
Antibody selection method against IGF-IR
Antibodies against insulin like growth factor I receptor (IGF-IR), methods for their production, pharmaceutical compositions containing the antibodies, and uses for the antibodies are disclosed....
|
|
|
7579152 |
SENP1 as a marker of cancer development and target for cancer therapy
The present invention relates to compositions and methods for the use of SENP1 as a marker for cancer diagnosis, specifically prostate cancer. Still further, it relates to the use of inhibitors of...
|
|
|
7579156 |
Fluorescent phospholipase assay, phospholipase A2 inhibitor and stimulator, and the use thereof
A fluorescent phospholipase assay is disclosed. Further disclosed are the identification of alpha-1-antitrypsin as a phospholipase A 2 stimulator and phospholipase C inhibitor and the...
|
|
|
7579141 |
Proteins expressed by Mycobacterium tuberculosis and not by BCG and their use as diagnostic reagents and vaccines
The invention provides polypeptides encoded by open reading frames present in the genome of Mycobacterium tuberculosis but absent from the genome of BCG and diagnostic and prophylactic...
|
|
|
7579170 |
Method for preparing monoclonal antibodies capable of activating effector cells expressing FCγRIII
The invention concerns a method for obtaining and selecting monoclonal antibodies by an ADDC-type test, said antibodies capable of activating type III Fcγ receptors and having a particular glycan...
|
|
|
7579322 |
Compositions and methods for promoting myocardial and peripheral angiogenesis
Methods, compositions and devices are disclosed for use in growing new blood vessels to restore or improve blood flow to ischemic tissues and organs of the body. Compositions comprising IGD...
|
|
|
7579195 |
Simple membrane assay method and kit
The present invention is to provide a simple membrane assay method for detecting or quantitating an analyte in a specimen sample using an assay device equipped with a membrane bound with a...
|
|
|
7579004 |
Naturally processed measles virus peptides eluted from class II HLA molecules
A preparation of peptides eluted from class II HLA molecules is disclosed. Methods of decreasing measles infections comprising inoculating human patients with a vaccine comprising one or more of...
|
|
|
7579159 |
Assays, antibodies, and standards for detection of oxidized and MDA-modified low density lipoproteins
Immunoassays for malondialdehyde-modified low density lipoprotein (MDA-modified LDL) and oxidized low density lipoprotein (OxLDL), monoclonal antibodies (and the cell lines for them) for use in the...
|
|
|
7579187 |
Anti-A33 antibody
The present invention provides: an antibody or a antibody fragment thereof, which can bind to A33, which specifically attacks A33-expressing tumor cells with the use of ADCC and CDC based on the...
|
|
|
7579160 |
Methods for the detection of cervical cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic...
|
|
|
7579142 |
Methods for purification of bacterial cells and components
The present invention relates to a method for the selective purification of bacterial cells and/or cell components, whereby the purification is performed by means of a solid support.
|
|
|
7579158 |
Cellular retinoic acid binding protein II as a marker for breast cancer
The present invention relates to the diagnosis of breast cancer. It discloses the use of protein cellular retinoic acid binding protein II in the diagnosis of breast cancer. It relates to a method...
|
|
|
7575883 |
Cytochrome c acetylation
Modulation of cytochrome c acetylation, e.g., with a SIR polypeptide, enables interventions that modulate lifespan regulation and cell proliferation, e.g., by modulating apoptosis and/or...
|
|
|
7575871 |
Method of diagnosis and kit of parts therefor
A method for diagnosing coeliac disease in a patient comprising (a) providing an antibody sample from the patient to be tested, (b) contacting said antibody sample with cross-linked extracellular...
|
|
|
7575929 |
Diagnosis of multiple sclerosis with diketopiperazines
The present invention relates to the diagnosis and monitoring of diseases and conditions by quantifying markers, including degradation products of disease-associated proteins, such as...
|
|
|
7576333 |
Optical interrogation system and method for using same
An optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which can be located within the wells of a microplate. In one embodiment,...
|
|
|
7576189 |
Antibodies to human vascular endothelial growth factor 2 and methods of using the same
Disclosed is a human VEGF2 polypeptide and DNA(RNA) encoding such VEGF2 polypeptides. Also provided is a procedure for producing such polypeptide by recombinant techniques and antibodies and...
|
|
|
7575877 |
Method of diagnosing tuberculosis
The present invention relates to a method of diagnosing tuberculosis in a subject, said method comprising steps of: detecting anti- Mycobacterium tuberculosis (M.tb.) isocitrate dehydrogenase...
|
|
|
7575866 |
Ligand/binding partner bio-labeling systems
The present invention relates to methods and compositions which utilize binding relationships between detector molecules and their ligands for labeling molecules of interest in vivo. A “target”...
|
|
|
7576183 |
Structure-based receptor MIMICS targeted against bacterial superantigen toxins
The invention provides therapeutic compositions useful in the treatment of bacterial superantigen mediated conditions, such as Toxic Shock Syndrome. The compositions comprise genetically engineered...
|
|
|
7575878 |
Methods of inhibiting leptin-induced signaling with fibronectin III domain antibodies
The invention relates to a new type of leptin receptor antagonist, which is able to prevent leptin signaling without preventing the binding of leptin to the leptin binding domain. More...
|
|
|
7575938 |
Method for diagnosing liver diseases
The present invention relates to a method for diagnosing a liver disease rapidly in an early stage. More particularly, the present invention relates to a monoclonal antibody against asialo α1-acid...
|
|
|
7575873 |
Reagents for diagnosing, imaging and treating atherosclerotic disease
The invention provides a novel human Mab Fab, cloned by phage display, and its use in diagnostic and therapeutic methods. In particular the invention provides a method for analyzing the OxLDL...
|
|
|
7575876 |
Biomarkers for neurodegenerative disorders
The present invention provides methods for diagnosing neurodegenerative disease, such as Alzheimer's Disease, Parkinson's Disease, and dementia with Lewy body disease by detecting a pattern of gene...
|