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7604953 |
Bioamplification for microbial sensor signal transduction
A process of detection of the causative agent of Johne's disease ( Mycobacterium avium subsp. paratuberculosis ) (MAP) by detecting shedding of surface protein of MAP. A preferred way is use of...
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7604950 |
Methods for early detection of pregnancy in cows
Disclosed are methods for determining the pregnancy status of a cow by detecting a pregnancy-associated glycoprotein (PAG) level that comprises proteins present in an acidic protein fraction of day...
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7604946 |
Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in...
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7604957 |
Method for diagnosing immunologic food sensitivity
A method for food sensitivity panel testing (for sensitivities other than gluten sensitivity) by detecting IgA antibodies in serum is disclosed. A method for testing stool samples for the presence...
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7604948 |
Biomarkers for diagnosing an autism spectrum disorder
The present invention provides methods of identifying biomarkers indicative of the presence of a neurodevelopmental disorder, including an autism spectrum disorder, in an individual, using...
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7604947 |
Detection and modulation of cancer stem cells
The invention relates to method for detecting and modulating the expression and activity of REX-1. As described herein, REX-1 is expressed in certain cancer cells, including cancer stem cells. The...
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7604959 |
Cell-based assays employing voltage and calcium dyes
Disclosed are novel compositions and methods employing cyclic nucleotide-gated channels and fluorescence dyes and other indicators in detecting changes of intracellular cAMP levels, for instance in...
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7605004 |
Test strip for a lateral flow assay for a sample containing whole cells
A test strip for conducting a lateral flow assay for detection of an analyte in a sample that contains cells and fluid is provided, as well as methods for making and using the test strip. This test...
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7604951 |
Method for identifying compounds that modulate RXR associated processes with IgE production
The present provides compounds capable of modulating IL-4 receptor-mediated IgE production, as well as IL-4 induced processes associated therewith, methods and kits for identifying such compounds...
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7604952 |
Detection and determination of the stages of coronary artery disease
A method having clinically sufficient degree of diagnostic accuracy for detecting the presence of coronary artery disease in a human patient from the general population and for distinguishing...
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7604939 |
Methods of identifying active BRM expression-promoting HDAC inhibitors
The present invention provides screening methods for identifying BRM expression-promoting histone deacetylase (HDAC) inhibitors, diagnostic methods for determining the suitability of treatment of a...
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7604949 |
Methods and compositions that affect melanogenesis
The invention provides methods of screening for compounds that affect melanogenesis and the function of P protein in organisms, cells, or cell-free systems. The invention further relates to...
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7604981 |
Excitable target marker detection
A variety of types of molecules are detected and/or analyzed using an integrated micro-circuit arrangement. According to an example embodiment of the present invention, a micro-circuit arrangement...
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7605003 |
Use of biomarkers for detecting ovarian cancer
The present invention relates to a method of qualifying ovarian cancer status in a subject comprising: (a) measuring at least one biomarker in a sample from the subject and (b) correlating the...
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7604954 |
Method for evaluating kidney function in a feline
Methods for ( 1 ) evaluating feline kidney function by determining ghrelin level in feline tissue or biofluid and correlating the ghrelin level directly to kidney function and ( 2 ) diagnosing...
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7601542 |
Analytical method for protein mapping using hydrogen/deuterium exchange
Analytical methods using hydrogen/deuterium exchange are provided which reduce or eliminate the back-exchange of deuterium for hydrogen. The methods, which are useful in protein and peptide...
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7601504 |
Protein achieving improved blocking efficiency
It is intended to provide a method of conveniently screening a novel protein or a novel partial sequence protein having a blocking ability based on amino acid sequence data; and a protein achieving...
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7601507 |
Electronic methods for the detection of analytes
The present invention is directed to the detection of target analytes using electronic techniques, particularly AC techniques.
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7601505 |
Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer
The invention relates to nucleic acid molecules and proteins associated with breast cancer. Compositions, kits, and methods for detecting, characterizing, preventing, and treating human breast...
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7601517 |
Split protein self complementing fragments, systems, and methods of use thereof
Briefly described, embodiments of this disclosure include split protein systems, fusion proteins, methods of producing the split protein systems, methods of screening macromolecular delivery...
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7601540 |
Gamma secretase notch biomarkers
The present invention relates to the biomarker TFF-3 that measures γ-secretase mediated Notch processing. TFF-3 has utility in predicting and/or determining in vivo Notch-related toxicity...
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7601502 |
Prime boost vaccine for the protection of equines against equine influenza
The present invention is concerned with vaccinating equines against the equine influenza virus (EIV). It has now been found that adequate protection against equine influenza in equines can be...
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7601684 |
Diagnosis and treatment of disorders of iron metabolism
The invention concerns a method for detecting disorders of iron metabolism and in particular the differential diagnosis of disorders of iron metabolism by means of three independent parameters. The...
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7601506 |
Identification of leucocytes bearing diagnostic markers for transmissible spongiform encephalopathies
The invention provides a simple method for diagnosing a non-symptomatic or symptomatic human or animal with transmissible spongiform encephalopathy.
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7598093 |
Nanoparticle and microparticle based detection of cellular products
Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic...
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7598081 |
Materials and procedures for the purification of cells
The subject invention provides new materials and methods for the efficient isolation and purification of stem cells. Specifically, conductive immunopolymers with stem cell specific antibodies can...
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7598079 |
Assay for identifying compounds which affect stability of mRNA
The present invention relates to an assay for the identification of biologically active compounds, in particular to a reporter gene assay for the identification of compounds, which have an effect...
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7598042 |
Early prostate cancer antigens (EPCA), polynucleotide sequences encoding them, and their use
A novel prostate cancer marker is described that is found in cancerous and normal prostate cells of individuals that have prostate cancer but is not found in the prostate of individuals without...
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7598028 |
Compositions and methods for detecting and treating prostate disorders
The present invention relates to compositions and methods for the detecting, treating, and empirically investigating cellular proliferation disorders and cellular motility disorders. In particular,...
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7598051 |
Compositions and methods for the therapy and diagnosis of ovarian cancer
Compositions and methods for the therapy and diagnosis of cancer, particularly ovarian cancer, are disclosed. Illustrative compositions comprise one or more ovarian tumor polypeptides, immunogenic...
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7598045 |
C-type LECTIN transmembrane antigen expressed in human prostate cancer and uses thereof
A novel gene (designated PC-LECTIN) that is highly overexpressed in prostate cancer and its encoded protein is described. PC-LECTIN in normal human tissues is restricted to testis, but is highly...
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7598090 |
Biosensor
A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an...
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7598030 |
Antibodies against cancer produced using masked cancer cells as immunogen
This disclosure relates to methods for selecting antibodies having desirable characteristics from a population of diverse antibodies. More specifically, this disclosure provides methods for...
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7598352 |
Method of identifying polypeptide monobodies which bind to target proteins and use thereof
A method of identifying a polypeptide monobody having target protein binding activity, said method comprising: providing a host cell comprising (i) a reporter gene under control of a 5′...
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7598041 |
HIV-1 VPR interactions with mitochondrial apoptosis inducing factor and methods of using the same
Assays to identify Vpr/AIF interaction and translocation inhibitors are disclosed.
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7598043 |
Use of vascular endothelial growth factor receptor 1+ cells in treating and monitoring cancer and in screening for chemotherapeutics
The present invention is directed to a method of inhibiting tumor formation in a cancer patient at a site remote from sites of prior tumor formation and to a method of preventing metastases. These...
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7598044 |
Procedure and device for determining the concentrations of at least two ligands
In a procedure for determining the concentrations of ligands contained in a sample wherein a first ligand is bond-specific to a first receptor and a second ligand is bond-specific to a second...
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7598094 |
Methods and apparatus for detecting cardiac injury markers using an acoustic device
Methods for detecting cardiac injury by detecting one or more cardiac markers are provided. A plurality of particles, each of which is coated with a capture agent having an affinity for a cardiac...
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7598052 |
Expression profile of thyroid cancer
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression...
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7598351 |
Antibody and use thereof
The anti-19P2 ligand monoclonal antibodies of the invention (in particular P2L-1Ca) have very high binding ability and can neutralize the arachidonic acid metabolite releasing activity of the 19P2...
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7595151 |
Methods and compositions for diagnosis and treatment of influenza
The invention provides method and compositions for determining the presence and amount of an influenza virus in a sample including high risk strains of Influenza A. Also provided are methods for...
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7595165 |
Method of measuring activation of effector cells
The invention relates to a method of measuring the activation of an effector cell belonging to the immune system, which may or may not be transformed, using a monoclonal (AcMo) or polyclonal...
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7595155 |
Multiplex detection probes
The present invention comprises detection probes utilizing vesicles or soluble bodies to retain multiple mass tag molecules. The detection probes may be used to simultaneously assay a plurality of...
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7595159 |
Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
The present invention identifies a number of gene markers whose expression is altered in neurodegenerative diseases (ND). These markers can be used to diagnose or predict ND in subjects, and can be...
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7595147 |
Methods to identify agents that bind the flap-tip helix of RNA polymerase
The invention provides methods to identify moieties which specifically bind the flap-tip helix of the β subunit of RNA polymerase and to identify inhibitors of the interaction between those...
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7596455 |
Crystallization of IGF-1
Crystalline IGF-1 is provided along with a method for production thereof. Crystallizing IGF-1 comprises the steps of mixing an aqueous solution comprising IGF-1 with a reservoir solution comprising...
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7595170 |
Apparatus and method for measuring concentrations of molecules through a barrier
An apparatus and method for detecting the presence and measuring the concentrations of molecules through a barrier and/or at a distance utilizes the principle of chemical/electrostatic attraction...
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7595166 |
Methods of screening modulators of T2R taste receptors
The invention provides nucleic acid and amino acid sequences for a novel family of taste transduction G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic...
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7595202 |
Analysis method using reporter (label) intermolecular interaction
The present invention provides a method for controlling the spatial arrangement of an energy donor and an energy acceptor in a reaction complex in order to carry out the measurement with good...
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7595168 |
Method of screening for substances useful for transdifferentiation of microglia into neurons
According to the present invention, there is provided a method of screening for a substance useful for transdifferentiation of microglia into neurons, a method of producing neurons, and a method of...
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