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8865414 Detection conjugate and method for analysis  
The invention provides a combination of reagents as a test kit containing a detection conjugate having a binding portion and a reagent for deactivating of the fluorochrome portion by interaction...
8865179 Aptameric IgE peptides in a protein scaffold as an allergy vaccine  
A method is disclosed wherein an antigenic B-cell epitope is discovered by in vitro transcription and translation of pre-determined sequence on thermostable protein scaffolds detected by...
8865164 Detecting complement activation  
Methods of detecting complement activation including steps of detecting in a sample from a subject a level of iC3b wherein the detecting involves specific interaction between the iC3b and a...
8865411 Methods of identifying modulators of TDP-43 mediated cellular toxicity  
Compositions and methods are disclosed for identifying agents useful for the treatment of proteinopathies.
8865441 Efficient cell-free hydrogen production  
Cell-free synthesis of hydrogen from glucose and cellulosic hydrolysates is provided. Bacterial cells are modified to express high levels of (i) active [FeFe] hydrogenase; (ii) ferredoxin; and...
8865398 Combination hepatitis C virus antigen and antibody detection method  
An in vitro method that allows detection of hepatitis C by detecting hepatitis C virus (HCV) core protein and antibodies to HCV core protein (anti-core antibodies) in a single assay is provided....
8865413 Pancreatic cancer targets and uses thereof  
The present invention provides a method for diagnosing and detecting diseases associated with pancreas. The present invention provides one or more proteins or fragments thereof, peptides or...
8865075 Multi-task immunoaffinity device secured to a peripheral box and integrated to a capillary electrophoresis apparatus  
The present invention relates to an immunoaffinity device for capturing one or more analytes present at high or low concentrations in simple or complex matrices. The device is designed as a...
8865412 Methods and assays for oversulfated glycosaminoglycans  
Methods and assays for oversulfated glycosaminoglycans are provided. In an embodiment, the present disclosure provides a method for detecting oversulfated glycosaminoglycan (OS-GAG) in a heparin...
8865415 Methods and kits for measuring von Willebrand factor  
Methods and kits for measuring levels of von Willebrand factor function in a sample without using a platelet aggregation agonist, such as ristocetin, comprising recombinant glycoprotein IbĪ± having...
8865416 Analyte sensors, methods for preparing and using such sensors, and methods of detecting analyte activity  
Analyte sensors, methods for producing and using analyte sensors, methods of detecting and/or measuring analyte activity, detecting pH change, and/or, controlling the concentration of an analyte...
8865422 Method for the diagnosis of tuberculosis  
A method for the diagnosis of a tuberculosis infection caused by Mycobacteria belonging to the Mycobacteria tuberculosis complex group (MTC) in an animal including a human being, which comprises...
8865477 Water soluble nanocrystalline quantum dots capable of near infrared emissions  
A novel quantum dot capable of near infrared emissions at wavelengths of 750-1100 is made by forming solid solutions of metal sulfide, metal selenide or metal sulfide selenide by incorporating a...
8865479 Screening assays and methods  
Screening assays and methods of performing such assays are provided. In certain examples, the assays and methods may be designed to determine whether or not two or more species can associate with...
8865408 Signature for the diagnosis of cancer aggressiveness and genetic instability  
The present invention relates to a method for diagnosing aggressiveness and/or genetic instability of a cancer in a patient from a cancer sample of the patient. The method includes measuring in...
8865476 Particle switching systems and methods using acoustic radiation pressure  
The present invention comprises methods and systems that use acoustic radiation pressure.
8865418 Immunoanalytical method and system using mass spectrometry technology  
An immunoanalytical system in which, after a sample such as a patient's serum is subjected to a pretreatment by an immunological pretreatment device, the sample is subjected to light detection by...
8865454 Flow through system, flow through device and a method of performing a test  
The invention relates to a flow through system for quantifying a target component in a liquid. The flow through system comprises a flow-through device comprising a flow path comprising a marker...
8859211 Immunodisplacement electrophoresis  
The disclosure teaches a method for the analysis of a sample by electrophoresis, making use of a binding partner for a target compound or group of target compounds which may be present in the...
8859209 Reimmunization and antibody design  
The present invention relates to methods for harvesting of antibodies from an antibody library. The antibodies are harvested by utilizing a certain epitope that is analogous to the epitope of the...
8859212 Method of extracting food component, food inspection method and food inspection kit  
Provided is a technique of extracting a component in a food from the food by using a reducing agent that is inexpensive and has a mild reducing action. A component in a food is extracted by mixing...
8859210 Method for identifying allergenic proteins and peptides  
A method for identifying allergenic proteins and peptides. More specifically, a method for identifying allergenic milk proteins and/or peptides including the steps of: providing at least one...
8859214 PAS kinase assays  
The present invention is directed towards methods for measuring and assaying PAS Kinase activity. The methods are useful, for example, for detecting PASK activity in a cell, and for screening for...
8858938 Human monoclonal antibodies against Hendra and Nipah viruses  
The present invention relates to monoclonal antibodies that bind or neutralize Hendra or Nipah virus. The invention provides such antibodies, fragments of such antibodies retaining Hendra or Nipah...
8859213 Method for diagnosing melanocytic proliferations  
The invention provides a method for diagnosing a melanocytic proliferation in a subject comprising staining a sample of lesional melanocytes with an antibody against soluble adenylyl cyclase (sAC)...
8858884 Coupled enzyme-based method for electronic monitoring of biological indicator  
A sterilization indicator system and method of using the system to determine efficacy of a sterilization process. The system includes a vial having a first compartment containing spores of one or...
8859215 Cell binding assay  
The present invention relates to a fluorescent cell binding assay combining pre-labeling and Western blotting. Intact cells are incubated with pre-labelled binders preferably followed by SDS PAGE...
8859208 System producing infectious recombinant influenza virus  
The invention provides compositions and methods useful to prepare segmented, negative strand RNA viruses, e.g., orthomyxoviruses such as influenza A viruses, entirely from cloned cDNAs and in the...
8859295 System and method to measure dissociation constants  
A system and method for determining the dissociation constant for a particular ligand is disclosed. In accordance with certain embodiments, the method creates a chemical denaturation curve of a...
8859265 Lateral flow immunoassay device with a more rapid and accurate test result  
The present invention provides a lateral flow immunoassay device for qualitative or quantitative analysis of an analyte of interest in a whole blood sample with a more rapid and accurate result....
8859216 Method for noninvasive prediction or diagnosis of inflammation and infection in amniotic fluid of patients with premature rupture of membranes  
Provided is a method for noninvasive prediction or diagnosis of inflammation and/or infection in amniotic fluid leaked through the cervix into the vagina to predict the concentration of...
8852870 Systems and methods for diagnosis and prognosis of cancer  
Methods for diagnosing a cancer in a subject are provided that include determining an amount of autoantibodies immunoreactive to procathepsin D (pCD) in a sample obtained from the subject. Further...
8852898 L-threonine overproducing microorganism and method for preparing L-threonine using the same  
The present invention relates to a mutant microorganism producing a high concentration of L-threonine in high yield, prepared using site-specific mutation, not random mutation, such as treatment...
8852953 Immunodetection and quantification of pyrazolopyrimidine sedatives  
The invention relates to novel immunogens, antibodies, methods and kits for use in immunoassays to detect and quantify zaleplon, metabolites of zaleplon and indiplon. These are the first described...
8852447 Porous nanostructures and methods involving the same  
A method for simultaneously detecting and separating a target analyte such as a protein or other macromolecule that includes providing a porous silicon matrix on the silicon substrate, exposing...
8852592 Systems and methods for anti-PAX8 antibodies  
The present invention is related to the anti-PAX8 antibodies, kits, cocktails, and use of anti-PAX8 antibodies for detection of cancer.
8852871 Humanized anti-IL-10 antibodies for the treatment of systemic lupus erythematosus (SLE)  
Provided is a humanized or chimeric antibody or fragment thereof capable of binding to interleukin-10 (Th-10), wherein said antibody or fragment thereof is capable of being administered to a...
8852866 Method for producing and identifying soluble protein domains  
Methods for producing and identifying fragments of proteins, and more particularly to methods for generating and identifying soluble protein domains are disclosed based on a method for generating...
8852872 Methods for detecting oncofetal fibronectin  
Methods and products for the detection of oncofetal fibronectin indicating molecules in samples are provided. Methods for imaging of oncofetal fibronectin are provided. In some methods provided...
8852877 Apparatus and method for identifying a hook effect and expanding the dynamic range in point of care immunoassays  
The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For...
8852873 Maternal biomarkers for gestational diabetes  
Embodiments herein relate to the field of screening tools for fetal/maternal wellness, and, more specifically, to biomarkers for gestational diabetes. In various embodiments, the methods may...
8852869 Method of determining functional deficiencies in the complement system  
The present invention relates to a method of in vitro determining functional deficiencies in the lectin pathway of the complement system, the method comprises the steps of (a) diluting a mammalian...
8852955 Methods and systems for detecting biomolecular binding using terahertz radiation  
Provided herein are methods and systems for detecting biomolecular binding events using gigahertz or terahertz radiation. The methods and systems use low-energy spectroscopy to detect biomolecular...
8852922 Assay cartridges and methods of using the same  
Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber...
8846323 Enzyme sensors, methods for preparing and using such sensors, and methods of detecting protease activity  
Embodiments of the present disclosure provide for enzyme sensors, protease sensors, methods for producing and using the enzyme and protease sensors, methods of detecting and/or measuring protease...
8846319 Lateral flow strip assay with immobilized conjugate  
The present invention discloses analyte detection devices for detecting one or more analytes present in test samples, especially biological samples. In particular, the devices of the invention are...
8846869 Mutant protein capable of binding specifically and quickly to troponin I derived from human myocardium  
Provided is a mutant protein capable of binding specifically and quickly to troponin I derived from human myocardium. The mutant protein comprises a first mutant scFv antibody fragment 51 a second...
8846320 Haptens, hapten conjugates, compositions thereof and method for their preparation and use  
A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more...
8846321 Association of levels of HDL-cholesterol apolipoprotein CIII with the risk of coronary heart disease and cardiovascular events  
Presented herein are methods of diagnosing, assessing, and treating an individual at increased risk if developing coronary heart disease or cardiovascular event, based on the individual's level of...
8847009 Plant transformation without selection  
The invention provides methods for identifying regenerated transformed plants and differentiated transformed plant parts, obtained without subjecting plant cells to selective conditions prior to...