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8916357 Dynamic monitoring of activation of receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology  
Methods for identifying a compound capable of interacting with a Receptor Tyrosine Kinase (RTK) including providing a device capable of measuring cell-substrate impedance, adding test cells...
8916354 Bladder cancer diagnosis composition containing APE1/Ref-1 and bladder cancer diagnostic kit using same  
Provided are a bladder cancer diagnosis composition containing APE1/Ref-1, a bladder cancer diagnostic kit containing an antibody which specifically binds to the APE1/Ref-1, and a method of...
8916353 Circovirus sequences associated with piglet weight loss disease (PWD)  
The genome sequences and the nucleotide sequences coding for the PWD circovirus polypeptides, such as the circovirus structural and non-structural polypeptides, vectors including the sequences,...
8916603 Methods for treatment with bucindolol based on genetic targeting  
The present invention concerns the use of methods for evaluating bucindolol treatment for a patient, particularly one with heart failure. It concerns methods for determining whether to administer...
8911950 Methods and compositions for inhibiting the growth of hematopoietic malignant cells  
Disclosed herein are compositions and methods for reducing the growth of hematopoietic malignant cells (e.g., B-cell leukemia cells). The methods involve reducing the growth of hematopoietic...
8911954 Polypeptide linker and method of analyzing target material using the same  
A polypeptide linker comprising an antibody-binding region and an enzyme cleavage region, and related compositions, kits, and methods of using same.
8912010 Thyroxine immunoassay using fluorescent particles  
Provided are a base plate and a method for thyroxine immunoassay, which are capable of decreasing the signal change rate caused by temperature change in a high-sensitivity immunoassay method for...
8911956 Methods of use for an immunoassay detecting fragment Ba  
Methods, compositions and kits for detecting the complement Factor B cleavage product Ba in a biological sample are described. These methods, compositions and kits are useful in convenient,...
8911953 TDF-related compounds and analogs thereof, analogs and bioactive fragments  
The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing,...
8911958 Methods for assessing modified LDL immune complexes in subjects having or at risk of coronary artery disease  
The present invention relates to the analysis of modified LDL in the context of immune complexes. In particular, ox-LDL and AGE-LDL are shown to predict the development of coronary artery disease...
8911957 Devices and methods for detecting cells and other analytes  
The invention features methods, devices, and kits for the isolation of analytes (e.g., a cell). A sample containing a desired analyte is introduced into a microfluidic device containing moieties...
8911952 Method for integrin ligand discovery  
This invention relates generally to integrin ligand discovery and to a method of integrin ligand discovery base upon induction of ligand-induced epitopes. Such ligands have the potential to be...
8911959 Methods of detection of coccidioides species in bodily fluid  
Coccidioidomycosis (Valley Fever) is currently diagnosed by relying on infected individuals (humans, dogs, etc.) to generate antibodies against the fungus. Since the immune response against Valley...
8911955 Virus detection device and virus detection method  
A virus detection device includes a diffusion unit configured to diffuse a virus in a gas as an inspection target into an aqueous solution containing a fluorescent antibody specifically adsorptive...
8911951 Plasma kallikrein fragments as diagnostic biomarkers for lung cancers  
Disclosed herein are diagnostic markers for lung cancer, isolated from serum glycoproteins. The disclosed diagnostic markers for lung cancer are specifically expressed only in the sera of lung...
8906388 Methods for detecting Mycobacterium tuberculosis antigens  
Method for detecting M. tuberculosis antigens, comprising: a) contacting a sample of a biological fluid with a solid support; b) adding an amount of a first antibody against at least one M....
8906389 Determination of the efficacy of an anti-mycobacterial vaccination  
The invention relates to methods and reagents for determining efficacy of vaccine, particularly of a tuberculosis vaccine.
8906632 Use of inhibitors of leukotriene B4 receptor BLT2 for treating asthma  
The present invention relates to the use of inhibitors of leukotriene B4 receptor BLT2 for treating asthma. More particularly, the present invention relates to a pharmaceutical composition for...
8907073 Nucleic acids encoding FOXD3 promoter and methods to isolate FOXD3 expressing cells  
DNA enhancer sequences are provided for use in constructs to identify early stage embryonic cells. The enhancer sequences can be used in parallel with short-hairpin RNA in a vector construct for...
8906701 Sonication-assisted metal-enhanced fluorescence (SAMEF)-based bioassays  
The present invention provides for sonication-assisted metal-enhanced fluorescence, luminescence, and/or chemiluminescence assay systems using low-intensity ultrasound waves to significantly...
8906634 Monitoring and inhibiting human immunodeficiency virus infection by modulating HMGB1 dependent triggering of HIV-1 replication and persistence  
Compositions and methods for modulating human immunodeficiency virus (HIV) infection involving substances that inhibit the ability of high mobility box 1 (HMGB1) protein to interact with natural...
8906603 Modified cardiolipin and uses therefor  
Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, oxidized cardiolipins, which may...
8906631 Method for identifying, expanding and removing adult stem cells and cancer stem cells  
Described are the use of stem cell markers for the isolation of stem cells and the use of the obtained stem cells in, for example, research or treatment, such as for the preparation of a...
8906672 Gradient injection for biosensing  
A single injection gradient with a biosensor, both structural and methodological, achieves the binding of analyte to immobilized ligand over a wide concentration range without the necessity of...
8906633 Detection of synthetic cannabinoids  
The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens...
8906700 Methods and compositions for phototransfer  
Methods are described for phototransferring a compound from a first surface to a second surface. Compounds are described with photocleavable linkers. Compounds attached to a first surface through...
8906630 Assays for detecting pathogenic respiratory bacteria  
The present invention encompasses methods, assays and kits for the detection of pathogenic bacteria in a patient and for the differential diagnosis of pulmonary diseases associated with pathogenic...
8906669 Microfluidic multiplexed cellular and molecular analysis device and method  
A sequential flow analysis tool comprising a microfluidic device having a fluid path defined within a substrate between an input and an output is described. The device includes a capture chamber...
8906608 Methods for reducing the range in concentrations of analyte species in a sample  
The present invention relates to the fields of molecular biology, combinatorial chemistry and biochemistry. Particularly, the present invention describes methods and kits for dynamically reducing...
8900515 Biosensing device  
The present invention provides a biosensing device, comprising an input unit, an analysis unit, a process unit, and a set unit for storing resulting data values as the basis for calibrating the...
8900819 ADRB2 cancer markers  
The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to...
8900818 Recombinant antigen for diagnosis and prevention of murine typhus  
The invention relates to a recombinant immunogenic composition from Rickettsia typhi. The invention also relates to a method for the use of the recombinant proteins in detection and diagnostic...
8901913 Microelectrode arrays  
Among others things, techniques, systems, and apparatus are disclosed for recording electrophysiological signals. In one aspect, a microelectrode sensing device includes a printed circuit board...
8900822 Fibrinogen assay  
The present invention is directed to a method of detecting intact fibrinogen, comprising the steps of: a) providing a sample containing at least some fibrinogen optionally converted at least in...
8900825 Immunogenic proteins of Leptospira  
The invention provides novel immunogenic proteins LigA and LigB from Leptospira for use in the development of effective vaccines and antibodies, as well as improved diagnostic methods and kits.
8900821 Identification of tissue for debridement  
Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a...
8900815 Platelet-derived microparticles as a novel diagnosis maker for a cardiovascular disease  
The present invention is directed to a method for evaluating whether coronary artery disease has progressed in a patient previously diagnosed as having the disease, wherein the method includes:...
8900882 Method of assaying complex and kit to be used therefor  
In the case of assaying the level of complex AB in a sample which likely contains the complex AB composed of substance A with another substance B, the complex is assayed by the competitive...
8900816 Assay for anti-EGFRvIII antibodies  
Detection of human antibodies directed against the tumor-specific protein Epidermal Growth Factor Receptor variant Class III (EGFRvIII) provide information on tumor burden and vaccine response....
8900850 Lateral flow based methods and assays for rapid and inexpensive diagnostic tests  
The invention provides reagents and methods for lateral flow assays and quantitative capture or determination of components, including cells, in a sample. In one aspect, reagents and methods for...
8900824 High-affinity monoclonal antibodies for botulinum toxin type B  
High affinity antibodies for binding epitopes of BoNT/B and hybridomas that produce such antibodies are described. The antibodies may be used in a kit for detecting BoNT/B in a sample.
8900817 Progastrin and liver pathologies  
Progastrin levels are determined to diagnose one or more liver pathologies.
8900820 Gene and protein expression profiles associated with the therapeutic efficacy of EGFR-TK inhibitors  
The present invention provides protein and gene expression profiles indicative of whether a patient afflicted with non-small cell lung cancer is likely to be responsive to treatment with a...
8895252 High energy radiation insensitive analyte sensors  
Enzyme based analyte sensors having radiation stabilizing agents are disclosed and described. More particularly, devices comprising a radiation stabilizing agent and methods for stabilizing...
8895251 Method for detecting human BPLP protein or a maturation product thereof  
The invention relates to an in vitro method for prognosis, diagnosis or determination of the evolution of a condition involving an altered production of Basic Proline-rich Lacrimal Protein (BPLP)...
8895258 Device for measuring proteins using biosensor  
A sensor for measuring a concentration of a specific protein using a biosensor with a measurement speed improved from a conventional impedance measurement. The sensor is capable of efficiently and...
8895705 Antibodies against a proliferating inducing ligand (APRIL) and methods of use thereof  
The present invention relates to a binding compound which binds to human APRIL. More specifically the invention provides, compositions of anti-APRIL specific antibodies and methods to use such...
8895021 Sequences of brachyspira, immunogenic compositions, methods for preparation and use thereof  
Novel polynucleotide and amino acids of Brachyspira hyodysenteriae are described. These sequences are useful for diagnosis of B. hyodysenteriae disease in animals and as a therapeutic treatment or...
8895257 Proteins used for the diagnosis of lyme borreliosis  
Chimera proteins including: (i) at least one sequence of a VlsE protein of a Borrelia species selected from B. garinii, B. burgdorferi sensu stricto and B. afzelii, and (ii) at least one sequence...
8895254 Biomarkers for ankylosing spondylitis  
There is described herein methods and peptides for detecting autoantibodies to NOG and/or SOST in a patient sample in order to diagnose of prognosticate Ankylosing Spondylitis in the patient.