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8993247 Assay for vascular calcification  
An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising obtaining a blood sample from an individual and measuring the level of a...
8993236 Electromagnetic molecular sensors and methods of using same  
Devices having an electromagnetic detector for the detection of analytes are disclosed. The devices include an electromagnetic detector, including effective inductance-change magnetic detectors,...
8993526 Method for counteracting the perception of sweat malodour by decreasing the function of carboxylic acid-binding olfactory receptors  
The invention relates to the identification of carboxylic acids, present in human sweat, as natural ligands of a specific subgroup of seven olfactory receptor (OR) belonging to class 1 within the...
8993277 Polynucleotides encoding beta-glucosidase variants  
The present invention provides compositions and methods for the expression of recombinant β-glucosidase variants, as well as their use in the production of fermentable sugars from cellulosic biomass.
8993246 Luminescence assay method  
A bioassay employing a first group including a lanthanide ion carrier chelate and a first recognition element, a second group including an antenna ligand and a second recognition element; where...
8993244 Screening for compounds having immunosuppressant activity by testing impact on leukocyte-specific calcium fluxes  
The invention relates to an assay for the identification of a compound having immunosuppressant activity, wherein a candidate compound is analyzed whether it blocks the Ca2+ flux in coronin 1...
8986936 Post-translation modified cardiac troponin T as a biomarker of a risk for heart failure  
The present invention relates to methods and kits for the prediction of risk for heart failure using post-translation modified forms of cardiac troponin T as a biomarker.
8987224 MicroRNA-198 as a tumor suppressor in pancreatic cancer  
A novel network of tumorigenic prognostic factors is identified that plays a critical role in advanced pancreatic cancer (PC) pathogenesis. This interactome is interconnected through a central...
8986703 Peptide sequences and compositions  
Provided is a polypeptide composition comprising one or more polypeptides, which polypeptides are immunogenic in a vertebrate such that they cause the vertebrate to produce immune system cells...
8986535 Erythropoietin receptor modified electrode and its preparation method and application  
The invention discloses an erythropoietin receptor modified electrode, which is a glassy carbon electrode with erythropoietin receptor as recognition element fixed onto the electrode surface via...
8986655 Compositions, devices, and methods related to prostate-specific membrane antigen  
PSMA ligands, compositions, and methods therefore are disclosed where the ligand is a peptide having the sequence X1X2CVEVX3QNSCX4X5 where X1-X5 are independently a natural or non-natural amino...
8981100 Use of novel coumarins as glutathione and thiol labels  
Fluorescent quinolizinocoumarin compounds substituted with electrophilic reactive groups that bind thiol compounds are described. The compounds are useful in detecting oxidative stress and...
8980566 Biomarkers for respiratory infection  
Methods of determining levels of activity of bacteria in the lungs of patients are described, in which levels of a marker of a bacterial iron scavenging processes (for example, siderophores) and...
8980565 Porphyrinic compounds for use in flow cytometry  
The present invention provides a method of detecting (e.g., by flow cytometry) a target compound, cell or particle, wherein the target is labelled with a detectable luminescent compound. The...
8980177 Fluidic indicator device  
Disclosed is a fluidic assay device for assaying at least one property of a liquid sample, the device comprising: (i) a liquid sample application region;(ii) at least one test flow path in liquid...
8981063 B7-H1 Antibodies  
The invention provides novel polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells containing the...
8980253 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase  
Provided are compositions comprising newly identified protein fragments of aminoacyl-tRNA synthetases, polynucleotides that encode them and complements thereof, related agents, and methods of use...
8980570 Composition for cancer prognosis prediction comprising anti-TMAP/CKAP2 antibodies  
The present invention relates to an antibody which specifically binds to TMAP (tumor associated microtubule associated protein)/CKAP2 (cytoskeleton associated protein 2) or a fragment thereof, and...
8980564 Predictive markers for taxane responsiveness and methods of use thereof  
Taxanes are widely used in the treatment of breast cancer, although there are currently no validated predictive markers for taxane responsiveness. While the mechanism by which taxanes induce...
8975034 Maternal biomarkers for gestational diabetes  
Embodiments herein relate to the field of screening tools for fetal/maternal wellness, and, more specifically, to biomarkers for gestational diabetes. In various embodiments, the methods may...
8975037 Methods of inhibiting tumor cell aggressiveness using the microenvironment of human embryonic stem cells  
The invention provides compositions comprising one or more isolated factors from a microenvironment of human embryonic stem cells (hESCs), including, but not limited to, Lefty and inhibitors of...
8975029 Integrin alpha-2 binding agents and use thereof to inhibit cancer cell proliferation  
The invention provides an integrin alpha-2 binding agent and methods of using an integrin alpha-2 binding agent to, e.g., inhibit proliferation of cancer cells, modulate tumor growth in a subject,...
8975081 Biomarker for monitoring development of diseases and assessing the efficacy of therapies  
The invention concerns a method for monitoring the development of a disease in a patient, and for assessing the efficacy of a therapy influencing on the CD73 level or activity in the patient, in...
8975087 Longitudinal assay  
Embodiments of the invention include methods for detecting and determining the concentrations of macro and small molecules, including bio-molecules, in a liquid or gaseous sample.
8975054 Microorganisims used to synthesize oligosaccharides  
The present invention relates to the enzymatic synthesis of oligosaccharides, particularly, sialylated oligosaccharides comprising the carbohydrate moeities of the gangliosides GM3, GD3, and GT3.
8975013 Process to control CO concentrations in fermentations  
A process for controlling concentration of CO in a bioreactor provides a direct and real time measurement of dissolved CO in a fermentation medium. The process for controlling concentrations of CO...
8975031 Method for predicting a need for renal replacement therapy (RRT)  
A method for predicting a need for Renal Replacement Therapy (RRT) in a patient comprises: determining a concentration of pi glutathione S transferase-(πGST) in a first urine sample from the...
8975016 Methods for direct fluorescent antibody virus detection in liquids  
The present invention describes a liquid direct fluorescence antibody assay that is rapid and sensitive to detect respiratory virus in infected cells. The assay includes centrifugation of the...
8975033 Human autoantibodies specific for PAD3 which are cross-reactive with PAD4 and their use in the diagnosis and treatment of rheumatoid arthritis and related diseases  
In one or more embodiments, the present invention provides a novel biomarker which provides a link between a distinct clinical phenotype and a biochemical effect of an autoantibody on an enzyme...
8975384 Tag peptide and use thereof  
The present invention provides a tag peptide comprising an amino acid sequence represented by the following formula (I): X1-Tyr-X2-Gly-Gln-X3 (I) (wherein X1, X2 and X3 are the same or different...
8975030 Method for cancer detection  
The present invention relates to the diagnosis and treatment of cancer, and specifically to a method of diagnosing the presence, status or metastasis of cancer by detecting plasma Hsp90α having...
8975069 Method for identifying antigen-specific regulatory T cells  
A method of identifying an antigen-specific regulatory T cell (Treg) from a subject is discussed wherein the method comprises quantitatively or qualitatively detecting co-expression of each of...
8975032 Test kit for plasma or serum antibody titer against periodontal disease-causing bacteria  
The object of the present invention is to provide: a test kit for an antibody titer or an antibody against a periodontal disease-causing bacterium in a blood sample, which enables the testing on a...
8969010 In vivo micro-invasive investigation device including a metal guide  
The invention relates to an analysis device, wherein said system includes at least one metal guide at one end of which is provided at least one series of pits to which are directly coupled...
8969009 Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual  
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample...
8968995 Detection, screening, and diagnosis of HPV-associated cancers  
Embodiments of the invention provide methods, polyclonal antibodies, monoclonal antibodies, assays, and kits for detecting HPV infection, including infection by various HPV genotypes, early and/or...
8969256 Solution microarrays and uses thereof  
The present invention relates to solution microarrays. In particular, the present invention relates to an aqueous 2-phase system for solution microarrays and uses thereof. The present invention...
8969340 Methods for treating chronic pelvic pain syndrome  
The present invention provides methods and compositions for treating chronic pelvic pain syndrome. In particular, the present invention provides methods and compositions for treating chronic...
8969255 Compound arrays for sample profiling  
The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds...
8969012 Immunogens for treatment of neoplastic and infectious disease  
The present invention relates to prophylactic and therapeutic methods of immunization against neoplastic and infectious diseases. The invention provides a method for identification of novel...
8969520 Reagent for assaying anti-treponema pallidum antibody  
To provide a reagent for assaying anti-Treponema pallidum antibody which reagent contains a polypeptide antigen and which reagent provides high assay sensitivity and high specificity, and to...
8969013 Method for identifying lineage-related antibodies  
In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of...
8969322 Extracorporeal devices and methods of treating complications of pregnancy  
The invention features extracorporeal methods for the treatment of a subject having a pregnancy related hypertensive disorder, such as pre-eclampsia or eclampsia. The invention also features...
8969530 Anti-clathrin heavy chain monoclonal antibody for inhibition of tumor angiogenesis and growth and application thereof  
A purified monoclonal antibody, or an. antigen-binding portion thereof, which specifically binds to human clathrin heavy chain (CHC) is disclosed. The antibody, or antigen-binding portion,...
8969011 Microorganism concentration process and device  
A process for capturing or concentrating microorganisms for detection or assay comprises (a) providing a concentration device comprising a sintered porous polymer matrix comprising at least one...
8969014 Methods for determining ligand binding to a target protein using a thermal shift assay  
The invention is directed to a method of determining whether a non-purified sample contains a target protein bound to a ligand of interest comprising the steps of: a) exposing said non-purified...
8969018 Methods and compositions for monitoring and risk prediction in cardiorenal syndrome  
The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects. In particular, the invention relates to methods...
8968677 Frazil ice conjugate assay device and method  
An improved apparatus and method for dispersion of a labeling conjugate in a diagnostic assay, the result being a one-step assay. By eliminating a conjugate pad as in conventional lateral...
8969023 Methods and compositions for treating alzheimer's disease  
Aspects of the invention relate to methods and compositions for treating Alzheimer's disease (AD). In some embodiments, the invention provides methods for screening and identifying compounds that...
8969099 Microanalysis methods and systems using field effect transistor  
Provided is a microanalysis method and system using a Field Effect Transistor (FET). The microanalysis method includes a channel region having a receptor molecule fixed; forming a nano-particle...