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6727346 Process for obtaining insulin precursors having correctly bonded cystine bridges  
The present invention relates to an improved process for obtaining a precursor of an insulin or insulin derivative having correctly bonded cystine bridges in the presence of cysteine or cysteine...
6720165 Methods for making antibody fragments and compositions resulting therefrom  
Improved methods for making antibody fragments, preferably F(ab′)2 fragments from various classes and subclasses of antibodies is described. Pretreatment of antibodies with deglycosylases or...
6716598 Protein recovery  
The invention herein provides a method for recovering a polypeptide comprising exposing a composition comprising a polypeptide to a reagent which binds to, or modifies, the polypeptide, wherein...
6716599 Method of hydrolyzing defatted jojoba meal with protease enzymes  
Hydrolyzed jojoba protein is provided which can be used in a variety of cosmetic formulations to enhance the desirable properties thereof. The preferred hydrolyzed jojoba is in the form of an...
6716642 Individually addressable micro-electromagnetic unit array chips in horizontal configurations  
The present invention provides electromagnetic chips and electromagnetic biochips having arrays of individually addressable micro-electromagnetic units, as well as methods of utilizing these chips...
6709655 Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof  
The present invention is directed to a pharmaceutical composition comprising F(ab′)2 antibody fragments that are preferably free from albumin and of whole antibodies and also substantially free of...
6692933 Method for producing a gluten-free peptide preparation and preparation thus obtained  
The invention relates to a method for producing a glutamine-rich gluten-free peptide preparation from gluten protein, comprising the steps of enzymatically hydrolysing wheat gluten using one or...
6689876 Cloning and sequencing of allergens of dermatophagoides  
Isolated DNA encoding allergens of Dermatophagoides (house dust mites) particularly of the species Dermatophagoides farinae and Dermatophagoides pteronyssinus, which are protein allergens or...
6660495 Tolerogenic fragments of natural allergens  
The present invention relates to a process for the controlled enzymatic cleavage of purified and depigmented active allergenic proteins from indoor and outdoor source materials, which process...
6642031 Microorganisms with ability to degrade indole and enzymes therefrom  
There is provided novel indole oxidase activity isolated from P. putida, such indole oxidase activity is believed to be useful in the biosynthetic production of indigo from its precursor indole....
6620916 Modified physiologically active proteins and medicinal compositions containing the same  
The present invention relates to a modified physiologically active protein, modified physiologically active proteins produced by the process and pharmaceutical compositions containing the same.
6617127 Synthesis and recovery of aspartame involving enzymatic deformylation step  
The invention relates to the synthesis of aspartame involving enzymatic deformylation of an N-formyl-α-L-aspartyl-L-phenylalanine compound by treatment with an enzyme having formylmethionyl...
6602681 Enzymatic production of a C-terminal α-amidated peptide or protein  
A C-terminal α-amidating enzyme of Xenopus laevis and precursor thereof produced by a recombinant DNA technique; a DNA coding for the enzyme or precursor thereof; a plasmid containing the DNA; a...
6602685 Identification of compound-protein interactions using libraries of protein-nucleic acid fusion molecules  
Disclosed herein is a method for detecting a compound-protein interaction, involving: (a) providing a compound library in which each member of the compound library is immobilized on a solid...
6596481 Dual markers  
The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA...
6589574 Process for preparation of protein-hydrolysate from milk protein  
The present invention provides a process for the preparation of protein hydrolysate from milk protein by treating milk protein with fungal protease at a pH of 7.5-8.5, a temperature of 40±5° C....
6579688 Stabilizing diluent for polypeptides and antigens  
Compositions for stabilizing polypeptides or antigens are described. These compositions are useful for stabilizing polypeptides or antigens stored in aqueous formulations. Such formulations can be...
6579696 Polymyxin B conjugates  
Compositions and methods are described for preventing and treating sepsis in humans and other animals. Surgical patients, low birth weight infants, burn and trauma victims, as well as other...
6569649 Compositions and methods for saccharide synthesis  
Processes for preparing oligosaccharides, polysaccharides, glycolipids, glycoproteins, and other saccharide compositions are provided which involve the enzyme facilitated transfer of a preselected...
6569664 Native TNF receptor releasing enzyme  
The present invention relates to methods of regulating TNF activity indirectly by regulating the activity or concentration of TNF receptor releasing enzyme (TRRE). Preferably, the TRRE activity is...
6555155 Method and apparatus for harvesting, digestion and dehydrating of krill hydrolysates and co-drying and processing of such hydrolysates  
Method and apparatus used in producing a feed product or premix and the products made by the method. A predetermined quantity of krill hydrolysate is added to a predetermined quantity of dry...
6555330 Oncogene-induced apoptosis in drug-resistant cells  
The present invention relates to a method of identifying a compound (agent) which modulates apoptosis in transformed cells. In one embodiment, the invention is a method of identifying a compound...
6555336 Method for preparing albumin hydrolysates  
In a method for preparing albumin hydrolysates from a starting material containing albumins in concentrated or isolated form, the starting material are homogenized with an aqueous solution at a...
6551794 Stable biotinylated biomolecule composition  
Stable compositions containing biotinylated molecules, such as enzymes, are provided. The compositions include a biotinylated biomolecule, a biomolecule protectant, a buffer, a bulking agent...
6551636 Modification of foaming properties of proteins  
The present invention provides methods for modifying whey protein preparations to improve their foaming and other functional properties utilizing limited proteolytic hydrolysis. The invention also...
6551997 Engineered polypeptides in personal care applications  
The present invention is directed to process for conditioning hair and skin in which the skin has applied to it a polypeptide having between 20 and 60 amino acids in a polypeptide, having cysteine...
6548077 Purifying type I collagen using two papain treatments and reducing and delipidation agents  
Purified collagen such a type I collagen is produced by a method containing steps of contacting collagen with a first proteolytic enzyme followed by contacting with a reducing agent and a second...
6544791 Nitrogenous composition resulting from the hydrolysis of maize gluten and a process for the preparation thereof  
The invention relates to a nitrogenous composition resulting from the enzymatic hydrolysis of an aqueous solution of maize gluten, having a ratio of the concentrations or inorganic phosphorus to...
6537749 Addressable protein arrays  
Disclosed herein are arrays of nucleic acid-protein fusions which are immobilized to a solid surface through capture probes which include a non-nucleosidic spacer group and an oligonucleotide...
6531131 Conjugate vaccine for Neisseria meningitidis  
A conjugate vaccine for Neisseria meningitidis comprising lipooligosaccharide which does not contain a lacto-N-tetraose antigen from which at least one primary O-linked fatty acid has been removed...
6531294 Preparation of pancreatic procarboxypeptidase B, isoforms and muteins thereof and their use  
Pancreatic carboxypeptidase B or an isoform or a mutein of carboxypeptidase B may be prepared by (a) expressing a natural or unnatural enzymatically inactive precursor form of carboxypeptidase B...
6524844 Process for preparing optically active 1-amino-4-(hydroxymethyl) cyclopent-2-ene derivatives  
The invention discloses a new method for producing enantiomer-enriched 1-amino-4-(hydroxymethyl)-cyclopent-2-ene derivatives of the general formulae (I) and (II) in which R1 is hydrogen or a...
6518058 Method of preparing polypeptides in cell-free system and device for its realization  
The present invention provides a method for synthesis polypeptides in a cell-free system by which products of synthesis are branched in a low molecular weight fraction and a fraction which...
6514941 Method of preparing a casein hydrolysate enriched in anti-hypertensive peptides  
The present invention relates, in general, to a casein hydrolysate, and, in particular, to a method of preparing a casein hydrolysate enriched in antihypertensive peptides.
6514703 Method for separating and characterizing functions potentially present in a biological sample containing nucleic acids  
The present invention is directed to a process for the separation and characterization of the functions potentially present in a biological sample containing nucleic acids, characterized in that...
6512014 Compositions containing bioemulsifiers and a method for their preparation  
A bioemulsifier composition useful for forming and stabilizing oil-in-water emulsions, comprising an esterase protein of 32.5 KD, found in association with emulsan in the bacteria Acinetobacter....
6506577 Synthesis and crosslinking of catechol containing copolypeptides  
The synthesis of moisture-resistant adhesive polypeptides, conditions for their use, and conditions for controlling characteristics of the crosslinked matrix are disclosed. By specifically...
6492136 Solid phase organic synthesis  
A method of synthesis of a material corresponding to the general formula: R3—X—Hcharacterized in that it comprises a material corresponding to the following general formula: being cleaved as...
RE37919 Recombinant DNA method for production of parathyroid hormone  
A recombinant DNA molecule coding for human parathyroid hormone operably linked to an inducible bacterial promoter, a leader growth hormone sequence, and a selective enzymatic cleavage site,...
6485921 UBCLP and uses thereof  
The invention concerns ubiquitin-conjugating enzyme-like protein (UBCLP) nucleic acid molecules, polypeptides, antibodies, and modulators. The invention also concerns screening assays which can be...
6485928 Use of granulysin as an antimicrobial agent  
The T cell activation marker, granulysin, is demonstrated to be an effective antimicrobial agent. It is used in vitro and in vivo to reduce the population of viable cells in a microbial...
6485932 Composition comprising immunoglobulin  
Liquid compositions for intravenous administration that comprise an aqueous solution of immunoglobulin and methods of preparing such compositions are disclosed. The solution has a pH in the range...
6472182 Process for producing transglutaminase by microorganism  
The present invention provides a process for producing a transglutaminase, which comprises culturing microorganisms of any of the genus Micrococcus, Clostridium, Torulopsis, Rhizopus and Monascus...
6465424 Anti-angiogenic agent and method for inhibiting angiogenesis  
The present invention relates to compositions that inhibit the proliferation and migration of endothelial cells. The compositions contain a pre-activation domain (“PAD”) from plasminogen, or a...
6465209 Methods of producing protein hydrolysates  
The present invention relates to methods of producing protein hydrolysates, comprising adding to a proteinaceous material one or more aminopeptidase(s) having glycine releasing properties and one...
6465410 Laundry detergent and/or fabric care composition comprising a modified antimicrobial protein  
A modified protein which comprises a catalytically active amino acid sequence of an antimicrobial enzyme and/or an amino acid sequence of an antimicrobial peptide linked to an amino acid sequence...
6465432 Isolated antioxidant peptides form casein and methods for preparing, isolating, and identifying antioxidant peptides  
The current invention provides antioxidative peptide fractions. The invention includes antioxidative peptides of casein having sequences of SEQ ID NOS:1-5. The invention includes methods for...
6465220 Glycosylation using GalNac-T4 transferase  
The use of human polypeptide N-acetylgalactosaminytransferase T-4 (GalNAc-T4) to glycosylate substrates is disclosed. The action of GalNAc-T4 can complement the activities of GalNAc-T1, -T2 and...
6461834 Clostripain catalyzed amidation of peptides  
The invention provides a method of producing a polypeptide having a C-terminal α-carboxamide group. It particularly concerns an enzymatic modification of selected substrate polypeptides which...
6455273 Method for producing a protein hydrolysate with low bitterness  
A method for producing a protein hydrolysate with low bitterness by contacting a protein with a protease having a low specificity to cleave a site of a hydrophobic amino acid residue in the protein.