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7794970 Method for generating F(ab′)2 antibody fragments  
Methods for generating F(ab′)2 fragments from antibodies using thermolysin as well as F(ab′)2 fragments and compositions comprising F(ab′)2 fragments generated by the method are described.
7790417 Stable biodegradable, high water absorbable polyglutamic acid hydrogel by 3-dimensional cross-linking and its preparation method  
The present invention relates to a method for the production of a stable biodegradable, high water absorbable γ-polyglutamic acid (γ-PGA) hydrogel by directly cross-linking (A) a γ-polyglutamic...
7785826 Method for the deacylation of lipopeptides  
The invention relates to a method for the enzymatic elimination of the N-acyl side chain from lipopeptides to form the corresponding nucleus, wherein the lipopeptide is prepared by fermentation,...
7785824 Hydrolysed casein product comprising tripeptides IPP and/or VPP  
Process for the preparation of a hydrolysed casein product comprising tripeptides VPP, IPP and/or LPP, wherein a substrate comprising casein or casein fragments is subjected to enzyme treatment...
7785825 Compositions and methods for dehydration and cyclization of peptides, synthetic compounds, and lantibiotics  
Lantibiotics are synthesized on ribosomes as prepeptides and post-translationally modified to a mature form. These modifications include dehydrations and cyclizations. Compounds and related...
7781158 Method of separating collagen from the various animal tissues for producing collagen solution and product using the same  
A method for separation the collagen from the various animal tissues is disclosed for preparing collagen solution and product using the same. The porcine tissues are processed to have proper form...
7780873 Bioactive complexes compositions and methods of use thereof  
A bioactive complex composition having enhanced oxidative stability, emulsion stability, mineral rich transparent beverages and a wide range of functional health benefits. The composition may...
7776565 Engineering intracellular sialylation pathways  
Methods for manipulating carbohydrate processing pathways in cells of interest are provided. Methods are directed at manipulating multiple pathways involved with the sialylation reaction by using...
7772357 Hydrolytically degradable polymers and hydrogels made therefrom  
A water soluble polymer comprising multiple degradable carbonate linkages in a backbone and, for each carbonate linkage in the backbone, an oligomer linked thereto by the carbonate linkage,...
7771725 Medicinal concentrate of arbovirus specific immunoglobulins and F(ab)'2 and/or Fab fragments  
The invention concerns a new medicinal product for the treatment of arboviruses, i.e.. a concentrate of immunoglobulins and F(ab)′2 and/or Fab fragments specific to said arbovirus as well as its...
7767415 Compositions and methods for modifying blood cell carbohydrates  
This invention relates to enzymatic removal of type A and B antigens from blood group A, B, and AB reactive cells in blood products, and thereby converting these to non-A and non-B reactive cells....
7759088 Stable biodegradable, high water absorbable γ-polyglutamic acid hydrogel by 3-dimensional cross-linking and its preparation method  
The present invention relates to a method for the production of a stable biodegradable, high water absorbable γ-polyglutamic acid (γ-PGA) hydrogel by directly cross-linking (A) a γ-polyglutamic...
7754466 Method for producing dipeptides  
The present invention provides a method of producing a dipeptide from starting materials that are available at low costs through a route industrially advantageous and simple. Dipeptides are...
7749742 Method for producing tripeptides and/or peptides longer than tripeptides  
A method is disclosed that allows the production of peptides having three or more amino acid residues easily, inexpensively and at high yield without going through a complex synthesis method. A...
7745171 Cell-free protein synthesis method using insect cell extract solution  
The present invention provides a preparation method of an insect cell extract solution for cell-free protein synthesis, the insect cell extract solution, a protein synthesis method in a cell-free...
7737089 Photoactivatable two-stage protective groups for the synthesis of biopolymers  
The present invention relates to a process for synthesizing biopolymers by stepwise assembly from protected synthesis building blocks which carry two-stage protective groups. The two-stage...
7727738 Methods for generating analogs of coenzyme A  
Methods to generate analogs of coenzyme A in vitro and in vivo are disclosed. The methods comprise reacting pantetheine or a derivative thereof with a reporter to form labeled pantetheine or a...
7727466 Disintegratable films for diagnostic devices  
The invention provides disintegratable film compositions for diagnostic test devices. The films are prepared with a combination of components that yield films of sufficient film strength and...
7727736 Soluble phospholipids for use in clotting factor assays  
The present invention provides a soluble phospholipid reagent and assays of clotting activity using the same. The methods of the invention can be used to carry out any clotting assay or other...
7723082 Polynucleotides and polypeptides coded by said polynucleotides involved in the synthesis of diketopiperazine derivatives  
The invention concerns novel isolated natural or synthetic polynucleotides and polypeptides coded by said polynucleotides, involved in the synthesis of diketopiperazine derivatives, vectors...
7718195 Process for separating lipids and proteins from biological material  
A process for separating non-denatured fat and lipids as well as non-denatured proteins from a material of organic origin is disclosed wherein the fat and proteins are separated at a temperature...
7704707 Method of producing microbial transglutaminase  
The present invention provides a neutral metalloprotease from actinomycetes which selectively cleaves a pro-structure part of a microbial protransglutaminase and a gene encoding said neutral...
7700314 Method for producing polyol-IFN-β conjugate  
PEG-IFN-β conjugates, where a PEG moiety is covalently bound to Cys17 of human IFN-β, are produced by a process of site specific PEGylation with a thiol reactive PEGylating agent. A pharmaceutical...
7696167 Cyclic peptide compound  
A cyclic peptide compound of the following general formula (I): Wherein R1, R2 and R3 are defined in the description, or a salt thereof. The compound (I) is useful for the prophylactic and/or...
7691603 Intracellular formation of peptide conjugates  
The invention includes methods and compositions for forming peptide conjugates intracellularly having a covalent linkage between a modifying group and a glycosylated or non-glycosylated peptide....
7674766 Mass spectrometry-based identification of proteins  
The invention provides a method to C-terminally label proteins in a complex sample and identify those proteins, e.g., using mass spectrometry.
7666830 Nutritional composition preventing bacterial overgrowth  
Protein hydrolyzates are used for prevention of bacterial overgrowth. In addition it was shown in sucklings mammals that specific protein hydrolyzates promote an intestinal flore pattern which is...
7632658 Method of using aminopeptidase to produce cleaved polypeptides  
A gram-negative bacterial cell is described that is deficient in a chromosomal gene present in a wild-type such cell which gene shares at least 80% sequence identity with the native sequence of...
7618796 Peptide-forming enzyme gene, peptide-forming enzyme, and peptide producing method  
The present invention provides a method for producing dipeptide using inexpensively acquirable starting materials by an industrially advantageous and simple pathway. Dipeptide is produced from...
7615244 Glycopeptide and peptide having a kokumi taste imparting function, and method of imparting the kokumi taste to foods  
Glycopeptides and peptides having the formula: where X represents a hydrogen atom or a sugar chain, provide a taste improving function, particularly a kokumi taste imparting function. Such...
7611864 Proinsulin polypeptide-oligomer conjugates  
Methods for synthesizing proinsulin polypeptides are described that include a contacting a proinsulin polypeptide including an insulin polypeptide coupled to one or more peptides by peptide...
7608697 Protein hydrolysates enriched in peptides having a carboxy terminal proline residue  
A method of enzymatically producing a protein hydrolysate from a protein substrate is described, wherein a proline-specific endoprotease or a composition containing a proline-specific endoprotease...
7604967 Lignin-blocking treatment of biomass and uses thereof  
Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment...
7585815 High throughput protein production screening  
Methods, compositions, and kits for the cell-free production and analysis of proteins are provided. The invention allows for the production of proteins from prokaryotic sequences or eukaryotic...
7579165 Methods for derivatizing protein or peptide with sulfonic acid groups  
The present invention provides a method for effectively introducing sulfonic acid groups into the N-terminus of a protein or a peptide. The method comprises a modification step to react a...
7569360 γ-glutamylcysteine producing yeast  
A yeast which harbors a mutant glutathione synthetase having one or both of mutations selected from the group consisting of a mutation to replace a threonine residue at the position 47 with an...
7560249 Method for the production of a heterologous protein by a fungus  
Production of heterologous protein by fungal cells is good when the feeding medium comprises a carbon source comprising 50 to 100 wt % of ethanol and an inducer.
7556962 Saccharide composition purification instrument  
The present invention provides a sugar chain purification instrument which can continuously and efficiently purify the sugar chain. According to the present invention, the instrument includes an...
7547509 Cyanovirin variant-polymer conjugates  
The present invention provides variants of cyanovirin-N and water-soluble polymer conjugates thereof, and methods of preparing such conjugates. The cyanovirin-N of the invention are particularly...
7531323 Diabetes-mediating proteins and therapeutic uses thereof  
Provided are protective and deleterious diabetes-mediating proteins and polynucleotides encoding same, transgenic animals expressing a diabetes-mediating protein, drug screening methods for...
7524661 Preparation of a therapeutic composition  
Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system, comprises a unique peptide having 31 amino acids and another unique peptide having 21...
7524655 Synthesis of oligosaccharides, glycolipids, and glycoproteins using bacterial glycosyltransferases  
This invention provides nucleic acid and amino acid sequences of fucosyltransferases from Helicobactor pylori. The invention also provides methods to use the fucosyltransferases to synthesize...
7514222 Site selective acylation  
Disclosed are novel polypeptides of a four helix bundle formed of two dimerized helix-loop-helix motifs, wherein either both have a sequence according to SEQ. ID No. 1, SEQ. ID No. 2, SEQ. ID No....
7498148 Method for universal enzymatic production of bioactive peptides  
The invention provides methods for making peptides from a polypeptide containing at least one copy of the peptide using clostripain to excise the peptide from the polypeptide. The methods enable...
7494675 Process for the production of animal feed and ethanol and novel animal feed  
A method for the production of ethanol and a modified animal feed is provided. The method replaces the starch in known corn-based animal feed with biomass fiber treated to make it more digestible...
7485855 On-probe sample cleanup system and method for MALDI analysis  
A system and method for cleanup of biological samples from contaminants prior to spectroscopy analysis. The system includes a support configured to hold a sample including a liquid having at least...
7485438 Method of producing polyvalent antigens  
Embodiments of the invention generally provide methods and compositions for producing polyvalent antigens. In one aspect, the invention provides a method for producing a cross-linked antigen. In...
7482137 Hybrid glycosylated products and their production and use  
The present invention relates to hybrid glycosylated products, and in particular, to natural products such as polyketides and glycopeptides, and to processes for their preparation. The invention...
7479278 Troponin I polypeptide fragments and uses thereof  
Polypeptides corresponding to stable, circulating degradation products of troponin I (TnI) are described. The fragments comprise a sequence of the N-terminus of native cardiac TnI with 95-115...
7476515 Affinity trap reactor and single-step process for purifying angiostatin-like fragment from human plasma using the same  
The present invention provides an affinity trap reactor that enables the reaction between an enzyme bound to a support and substrate to proceed efficiently without its applications being...