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8741557 Predicting graft rejection  
Prognostic methods useful in assessing patients who have received a transplant and reagents that can be used to carry out those methods are provided. The inventions are based, in part, on our...
8715995 Polypeptides having beta-glucosidase activity and beta-xylosidase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides...
8715958 Cell-free synthesis of proteins containing unnatural amino acids  
Methods are provided for the utilization of bacterial cell-free extracts in the synthesis of polypeptides containing unnatural amino acids at one or more specified residues of the polypeptide.
8715994 Polypeptides having beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same  
The present invention relates to isolated polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and isolated polynucleotides...
8715984 Modified tRNA containing unnatural base and use thereof  
In the method for introducing a noncanonical amino acid residue into a desired position in a protein, the structure of tRNA is so modified as to have improved affinity for aminoacyl-tRNA...
8703459 Catalytic domains of beta(1,4)-galactosyltransferase I having altered metal ion specificity  
Disclosed are mutants of galactosyltransferases that can catalyze formation of oligosaccharides in the presence of magnesium; mutants of galactosyltransferases having altered donor and acceptor...
8697844 Method of purifying pegylated proteins  
The invention relates to a method of purifying PEGylated proteins by removing impurities from samples containing PEGylated proteins, in particular, but not exclusively vitamin K-dependent blood...
8691526 Processing materials  
Biomass feedstocks (e.g., plant biomass, animal biomass, and municipal waste biomass) are processed to produce useful products, such as fuels. For example, systems are described that can convert...
8691515 Methods for early detection of blood disorders  
Disclosed herein are methods of detecting blood disorders, such as diabetes. In particular examples the method includes contacting a blood sample with an amine reagent, blocking an excess of the...
8679771 Specific N-terminal labeling of peptides and proteins in complex mixtures  
This invention provides general methods for selective labeling of proteins on their N-termini with synthetic peptides. The methods of this invention can be applied to the global proteomic...
8658394 Methods, cells and systems for incorporating non-canonical amino acids into proteins  
The present disclosure pertains to methods of incorporating one or more non-canonical amino acids into a protein during a translation of the protein in bacterial cells. The present disclosure also...
8652805 Trapping molecular segments in nano-gaps  
A molecule trapping method includes forming a fluid bridge between a first reservoir and a second reservoir, translocating a molecule from the first reservoir to the second reservoir through the...
8637306 Production of carrier-peptide conjugates using chemically reactive unnatural amino acids  
Provided are methods of making carrier polypeptide that include incorporating a first unnatural amino acid into a carrier polypeptide variant, incorporating a second unnatural amino acid into a...
8632993 Method for grass species identification  
The present invention relates to the use of at least one peptide comprising or consisting of a sequence selected from the group consisting of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4...
8628690 Nanoemulsion compositions and methods of use thereof  
A nanoemulsion composition having enhanced oxidative stability, emulsion stability, and health benefits. The composition may include individual ingredients or a synergistic blend of non-reducing...
8603794 Polypeptides having cellobiohydrolase 1 activity and polynucleotides encoding same  
The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to...
8603775 Method of disulfide crosslink forming in vitro protein synthesis  
It is an objective of the present invention to provide a method of synthesizing a protein having disulfide bonds using a reconstituted protein synthesizing system in a convenient manner with high...
8603793 Polypeptides having cellobiohydrolase 1 activity and polynucleotides encoding same  
The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to...
8603774 Extract of E. coli cells having mutation in ribosomal protein S12, and method for producing protein in cell-free system using the extract  
It is intended to provide an extract, kit and a process for synthesizing a protein in a cell-free system. The extract is characterized by being prepared from mutant Escherichia coli cells having a...
8597906 Glycosylation of molecules  
Described herein are methods and genetically engineered cells useful for producing an altered N-glycosylation form of a target molecule. Also described are methods and molecules with altered...
8586532 Method for selectively modifying a protein via transglutaminase catalyzed reaction  
The present invention relates generally to a novel method of introducing property modifying groups to a protein. In particular, the present invention relates to the derivatization of lysine...
8580557 Casein hydrolyzate, process for producing the same and use thereof  
The present invention relates to a casein hydrolysate containing free amino acids and in vivo indigestible peptides having minimally suppressed in vivo enzymatic digestibility, and expected to...
8580541 Lignin blockers and uses thereof  
Disclosed is a method for converting cellulose in a lignocellulosic biomass. The method provides for a lignin-blocking polypeptide and/or protein treatment of high lignin solids. The treatment...
8580537 Thermotolerant transglutaminase originating in actinomyces  
The present invention provides transglutaminases with improved heat resistance. Specifically, the present invention provides mutant transglutaminase proteins with improved heat resistance as...
8580329 Dry-mill ethanol plant extraction enhancement  
In a liquid stream capture process for extracting various components in a dry mill ethanol process, a converted mash is separated into sugars/carbohydrates and corn residue by rinsing the...
8563268 Polypeptide having tyrosinase activity  
The present invention relates to isolated polypeptides having tyrosinase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs,...
8557297 Method for processing crustaceans and products thereof  
The present invention contemplates the creation of a low fluoride oil processed from a phospholipid-protein complex (PPC) formed immediately upon a crustacean (i.e., for example, krill) catch. The...
8551714 Microfluidic devices  
Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various...
8552158 Method for the production of insulin-like growth factor-1  
Method for the production of IGF-I, characterized by cultivating a prokaryotic host cell comprising an expression vector containing a nucleic acid encoding a fusion protein comprising said IGF-I...
8541200 Cleavage of fusion proteins using Granzyme B protease  
A method for the preparation of a polypeptide of interest in authentic form by enzymatic cleavage of fusion proteins using Granzyme B protease (EC 3.4.21.79). There is also provided fusion...
8535907 Protein concentrates and isolates, and processes for the production thereof from toasted oilseed meal  
Protein concentrates and protein isolates, in addition to processes for the production of protein concentrates and protein isolates, are disclosed. In particular, the disclosure relates to the...
8535885 Detection of disease related genes  
The invention is directed to methods for the non-radioactive labeling, detection, quantitation and isolation of nascent proteins translated in a cellular or cell-free translation system. tRNA...
8530180 Method for identifying smoker or ex-smoker at risk of chronic obstructive pulmonary disease  
Specific nitroprotein biomarkers may be used as prognostic and diagnostic tools for COPD. Identification of certain specific nitroprotein biomarkers allows the development of targeted therapies...
8524470 Enzymatic antibody processing  
The current invention comprises a method for producing an immunoglobulin or immunoglobulin fragment with defined glycostructure comprising the following steps: a) providing an affinity...
8518665 Methods for making 3-indole-pyruvic acid from tryptophan using a tryptophan deaminase  
It is an object of the present invention to provide a procedure for realizing inexpensive and simple production of 3-indole-pyruvic acid. A transformant is made using a polynucleotide having a...
8518668 Method for making maturated insulin polypeptides in a fungal cell  
The invention is related to a method for making mature human insulin or an analogue thereof by culturing a fungi cell comprising a DNA sequence encoding a precursor for human insulin or an...
8519031 Protein-containing emulsions and adhesives, and manufacture and use thereof  
This invention provides emulsions and adhesives comprising proteins that can be isolated from a variety of sources including renewable plant biomass, and methods of making and using such emulsions...
8512980 Recombinantly modified plasmin  
Polynucleotides and polypeptides relating to a recombinantly modified plasmin(ogen) molecule are provided. The plasmin(ogen) molecule has a single kringle domain N-terminal to the activation site...
8507238 Polypeptides having cellobiohydrolase 1 activity and polynucleotides encoding same  
The present invention relates to polypeptides having cellobiohydrolase I activity and polynucleotides having a nucleotide sequence which encodes for the polypeptides. The invention also relates to...
8507221 Process for the expression of peptides of interest using GCSF as a fusion partner  
The present invention discloses an improved process for the production of desired recombinant peptides from bacterial cells by using G-CSF as a novel fusion partner for their high level expression...
8501685 Process for preparing peptide products for promoting cholecystokinin secretion and use of the peptide products  
A process for producing a peptide product having cholecystokinin secretion promoting effect, said process comprising hydrolyzing soybean residues with one or more proteases so that the peptide...
8492115 Cell-free synthesis of membrane bound polypeptides  
Methods are provided for the utilization of bacterial cell-free extracts in the synthesis of high yields of membrane-associated polypeptides.
8481284 Process of preparing conjugates of allium organosulfur compounds with amino acids, peptides, and proteins  
Processes using Allium tissue homogenates and extracts in a simple and cost-effective manner to maximize the yields and recovery of thiosulfinates from Allium tissues and related organisms...
8481677 Protein concentrate from starch containing grains: composition, method of making, and uses thereof  
The present invention relates to methods of producing a protein concentrate from a starch containing grain and uses thereof. In an exemplary embodiment, the protein concentrate produced is used to...
8476039 Hot spring bacterial strain BKH1 and protein isolated therefrom, concrete compositions, and uses thereof  
Disclosed is a Thermoanaerobacter sp. bacterial strain (BKH1) isolated from a hot spring, a purified protein (bioremediase) isolated from bacterial strain BKH1, as well as concrete compositions...
8460909 Engineered versions of polysialyltransferases with enhanced enzymatic properties  
The invention relates to poly-sialyltransferse polypeptides with enhanced solubility and activity and methods of using the poly-sialyltransferases for production of poly-sialylated end products,...
8450084 Chemo-enzymatic peptide synthesis via C-terminal ester interconversion  
The invention relates to a method for preparing an optionally N-protected amino acid C-terminal ester or an optionally N-protected peptide C-terminal ester, comprising transesterifying the...
8445223 Anionic acid-labile surfactants and methods of use  
Anionic acid-labile surfactants may generally comprise compounds represented by the formula: wherein R1 is independently selected from —(CH2)0-9CH3, R2 is selected from the group consisting of —H...
8440445 Neutral protease (NP) and product by using neutral protease for tissue dissociation as well as method for the production thereof  
The use of a neutral protease (NP) together with a collagenase consists in that a neutral protease which is not contained in a collagenase enzyme preparation and which is not produced by a...
8435756 Anionic acid-labile surfactants and methods of use  
Anionic acid-labile surfactants may generally comprise compounds represented by the formula: wherein R1 is independently selected from —(CH2)0-9CH3, R2 is selected from the group consisting of —H...