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4876194 Protein L and subfragments thereof, with immunoglobulin binding activity, a process for preparing thereof, reagent kit, pharmaceutical composition and a peptococcus magnus strain  
This invention relates to a new protein L and subfragments thereof with binding activity for all classes of immunoglobulins from different species, a process for preparing the same, a reagent kit,...
4874708 Process for the preparation of intra-venously administered gamma-globulins and the gamma-globulins obtained  
A solution of gamma-globulins, coming for example from Cohn's fractionation, is submitted to a step of fractionation with polyethylene-glycol, a step of moderated enzymatic treatment with pepsin,...
4866033 Oligopeptides from bovine blood  
Oligopeptide mixtures from deproteinized bovine blood dialyzate which are characterized by their RF values in thin-layer chromatography, as well as a method for their preparation.
4865975 Process for recuperation of the proteins lost by the dairy industry  
A process for the recuperation, in a form usable by Man, of the proteins present in the sullage of the dairy industry. This process is effected in a number of devices successively including a...
4863732 Injectable composition for inductive bone repair  
Aqueous suspensions of fibrillar atelopeptide collagen and osteogenic factor are effective injectable preparations for the repair of bone defects.
4863857 Polypeptide complementary to peptides or proteins having an amino acid sequence or nucleotide coding sequence at least partially known  
A method for determining the amino acid sequence of a polypeptide complementary to at least a portion of an original peptide or protein. In one aspect the method involves: (a) determining a first...
4863729 Method for preparing a macromolecular monoclonal antibody composition  
Macromolecular monoclonal antibody compositions are provided which are capable of selectively forming stable bonds to cells having a predetermined concentration of at least one surface antigen,...
4853231 Method for preparation of tastable matters consisting primarily of low molecular weight peptides  
Tastable matters consisting mainly of low molecular weight peptides are obtained from raw material meats of fishes, shellfishes, birds, beasts or whales, by a method including a step of finely...
4849352 Antibody purification process  
F(ab) fragments are isolated from an antibody containing source by contacting the antibody containing source with a papain-polyacrylamide matrix to produce F(ab) and F(c) fragments which are then...
4849403 Protein C activator, methods of preparation and use thereof  
A method and composition for assaying protein C is described. The method comprises reacting a protein C-containing medium with a protein C-activating activator preparation obtained from venom of...
4847096 Process for treating whey proteins, and product obtained  
To facilitate the separation off of fat from whey protein concentrates and simultaneously avoid protein losses, and obtain a whey protein concentrate having improved taste and storage stability a...
4840897 Modified human insulin and its use as starting material for the preparation of human insulin  
A novel modified human insulin of the general formula: ##STR1## wherein R is a hydrophobic or charged amino acid or a di- or tripeptide group, comprising a hydrophobic or charged amino acid or an...
4828988 Hybrid polypeptides comprising somatocrinine and alpha1 -antitrypsin, method for their production from bacterial clones and use thereof for the production of somatocrinine  
A fusion between DNA sequences coding for hAT and hGRF via a synthetic adaptor coding for an in vitro cleavable amino acid sequence is used to express hGRF at high levels in E. coli.
4828831 New conjugates of vinblastine and its derivatives, process for preparing them and pharmaceutical compositions containing them  
A description is given of conjugates of vinca alkaloid of the indole-dihydroindole type with a protein or a protein fragment, corresponding to the general formula ##STR1## in which R1 denotes a...
4826680 Pharmaceutical composition containing thymus extract fractions  
A pharmaceutical composition is described, which contains a fraction consisting of low molecular proteins and/or oligo peptides, and a yellow fraction containing riboflavine, which is associated...
4826818 Proteinaceous emulsifier, process for preparing same and emulsion type cosmetic compositions containing same  
A proteinaceous emulsifier can be obtained by reacting an amino acid ester with a hydrophilic protein in the presence of an endopeptidase to form decomposition products of the hydrophilic protein...
4816398 Casein phosphopeptide composition  
A casein phosphopeptide composition is prepared containing less than 4% phenylalanine, tyrosine and tryptophan, greater than 8% and less than 20% serine, a ratio of Ca+Mg+P/NT greater than 0.2,...
4814433 Method for obtaining a papain-free antibody fragment preparation  
A method for obtaining a papain-free F(ab')2 antibody fragment preparation derived from papain digested whole IgG antibody employing an antibody to papain for binding to and removing...
4808702 Decapeptides produced from bioadhesive polyphenolic proteins  
Methods are described for the preparation and isolation of novel decapeptides of the formula: ##STR1## wherein each X is independently selected from the group comprising hydroxyl and hydrogen,...
4806473 Process for enzymatic production of peptides  
A peptide having the formula A--Bwherein A represents an N-terminal protected amino acid residue or an optionally N-terminal protected peptide residue and B represents an optionally C-terminal...
4806346 Method for isolation of antigen specific immunoglobulin  
A process for preparing the purified F(ab)2 fragment of equine Ig(T) from horses hyperimmunized with snake venom which comprises: (a) passing crude diluted hyperimmune equine serum contianing...
4801534 Water soluble zanthylium derivative substrates  
Water soluble xanthylium derivative substrates of rhodamine 110 and rhodol permit spectrophotometric and fluorescent measurements of trypsin-like enzymes without the addition of organic solvent...
4798800 Process for isolating human globular domain NC1 of basal membrane collagen from human tissue  
The present invention provides human characterized by a molecular weight of about 170,000 Dalton, a hexameric structure with monomeric subunits with a molecular weight of about 28,000 Dalton and a...
4789663 Methods of bone repair using collagen  
A method of repairing bone defects by use of suspensions containing purified atelopeptide, reconstituted, fibrillar skin collagen or bone collagen powder or mixtures thereof is disclosed. The...
4783402 Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique  
A process for producing a primary or secondary alcohol derivative of a phosopholipid which comprises reacting the phospholipid with a primary or secondary alcohol in the presence of phospholipase DM.
4782019 Enzymatic production of sphingophospholipid derivatives  
A process for producing a sphingophospholipid derivative comprising reacting a sphingophospholipid with a specified compound having an alcoholic hydroxyl group selected from the group consisting...
4772584 Inhibitor of C5a-mediated chemotaxis  
Polypeptides are disclosed which inhibit the binding of the C5a chemotaxin to polymorphonuclear leukocytes by cleaving a six amino acid peptide from the carboxy-terminus of the C5a chemotaxin. The...
4769326 Expression linkers  
The present invention is based upon a general principle of providing specific oligonucleotide segments ("linkers", herein) to be attached in sequence to a cloned DNA coding segment. The linkers of...
4767714 Method for the preparation of yeast chromatin for isolation of p20 polypeptide  
A method for the preparation of pure yeast chromatin for isolation of p20 polypeptide includes breaking yeast cells in a buffer solution and separating the released chromatin. The chromatin is...
4758507 Products displaying the antigenicity of hepatitis B virus e antigens and methods of producing those antigens  
Polypeptides displaying the antigenicity of hepatitis B virus e antigens, DNA sequences coding for those polypeptides, antibodies to those polypeptides and methods of producing and using those...
4757007 Process for preparing hydrolyzed products of soy protein  
Two kinds of hydrolyzed protein having different characteristics respectively are obtained by hydrolyzing soy protein with protease and separating the mixture of hydrolyzed products using their...
4742159 Digitalis antibodies, process for the preparation thereof and the use thereof for the therapy of digitalis intoxications  
The present invention provides a process for the preparation of digitalis antibodies in which appropriate mammals are immunized with a digoxin bound to protein, the animal serum is obtained, the...
4734362 Process for purifying recombinant proteins, and products thereof  
The present invention relates to a process for recovering recombinant protein from refractile inclusion bodies of microorganisms which comprise disrupting cells, recovering refractile bodies...
4732852 Site directed peptidase cleavage  
Method for preparing peptides free of undesired amino acids or amino acid sequences employing site specific receptors and proteases to cleave unprotected enzymatically hydrolyzable bonds.
4713336 Gene for lignin degradation and uses thereof  
This invention relates to the field of lignin degradation. More specifically the invention relates to methods for selecting and isolating microorganism from nature that are capable of degrading...
4711846 Process for the production of L-aspartyl-L-phenylalanine methy ester or L-aspartyl-L-phenylalanine  
A process for the production of L-aspartyl-L-phenylalanine methyl ester of L-aspartyl-L-phenylalanine by contacting an appropriate microorganism or enzyme-containing fraction of said microorganism...
4711847 Preparation of secretin  
Secretin, which cannot be prepared directly by genetic engineering because of its carboxylic acid carboxyl-terminus, can be obtained by preparing secretylglycine by genetic engineering and then...
4710583 Dipeptides and process  
Synthesis of phenylserine ester (a) via benzaldehyde and glycine ester using serine hydroxymethyltransferase; and (b) via methyl benzoylacetate. Synthesis of hydroxy-aspertame or derivative by...
4710462 Cell proliferation inhibitor and method of preparation  
This invention comprises preparing a cell proliferation inhibitor by a nonextractive method from a tissue which has neither a high content of collagen, nor proteoglycans. The source of inhibitor...
4708934 α-amidation enzyme  
Peptidyl-glycine α-amidating monooxygenase is an enzyme extractable from medullary thyroid carcinoma cell lines and tissue samples, having a molecular mass of about 60,000 to 65,000 daltons. It...
4704359 Protease and process for production and use thereof  
Disclosed is a new protease having the following properties: (1) it is able to hydrolitically cleave a peptide bond between two adjacent basic amino acids in a peptide chain; (2) it has a...
4687739 Method for treating aqueous solution of soybean protein with enzymes  
There is provided a method for treating an aqueous solution of soybean protein to provide a calcium abundant bean soup drink. The method comprises the steps of adding endpeptidase to an aqueous...
4677065 Production of improved protein isolate derived from seeds of a grain legume  
Seeds of a grain legume of relatively low lipid content are processed under conditions found to yield an improved protein isolate which is well suited for human consumption. The seeds of the grain...
4672032 Dental enamel production  
Methods are provided for the formation of dental enamel crystals in biosynthetic matrix form by the nucleation of calcium solutions with enamel proteins and for the use of such enamel crystals as...
4668625 Process for preparing peptides  
The invention describes a process for preparing peptides. More particularly, a process for preparing L-α-aspartyl-L-phenylalanine C1 -C4 lower alkyl ester is described and claimed by enzymatic...
4666838 Process for the production of L-aspartyl-L-phenylalanine esters  
A process for producing L-aspartyl-L-phenylalanine alkyl or aryl esters wherein L-aspartic acid and L-phenylalanine which is esterified with an alkyl group having at least two carbon atoms, an...
4661443 Assay for measuring gene expression  
A DNA-directed in vitro assay for measuring the formation of the initial NH2 -terminal dipeptides or tripeptides which are characteristic of a particular gene product is disclosed. This invention...
4656128 Modified alkaline phosphatase  
This invention provides a proteolytically modified alkaline phosphatase which is irreversibly inactivated upon removal of divalent ions. The modified enzyme is particularly useful as a molecular...
4654302 Process for the preparation of desulfatohirudins  
The present invention relates to desulfatohirudins, to the preparation thereof, to pharmaceutical compositions containing these compounds, and to the use thereof.The desulfatohirudins of this...
4650856 Process for producing gluten having high solubility  
A process for producing gluten having high solubility which comprises heating an aqueous acidic solution of gluten and one or more proteins selected from the group consisting of albumins and...