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5810970 Paper strengthened with solubilized collagen and method  
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
5795729 Reductive, energy-transfer fluorogenic probes  
An energy transfer fluorescent probe for detecting a reagent is provided which includes a fluorescent reporter molecule and a quencher molecule positioned on the probe relative to the reporter...
5792623 Method for producing activated blood factors with a protease and a detergent  
Proenzymes or proforms of blood factors can be cleaved in the presence of a detergent or a chaotropic substance to produce active blood factors selected from the group consisting of Factor Va,...
5792664 Methods for producing and analyzing biopolymer ladders  
Methods of producing biopolymer ladders and their use to obtain structural information about the biopolymer. The ladders are produced by setting up catalytic cleavage and terminating reactions at...
5786165 Herbicide test method  
Potential herbicides can be identified by testing compounds in an AMP deaminase inhibition assay. Also disclosed is the use as a herbicide of a compound which is an inhibitor of AMP deaminase in...
5783413 Enzymatic process for producing a desired protein from an amino terminal extended protein  
An enzymatic process is presented for producing a desired protein from an amino terminal extended protein by reaction with one or more aminopeptidases, glutamine cyclotransferase and pyroglutamine...
5780439 Whey protein hydrolysates and mixtures thereof with casein and/or soy protein hydrolysates  
A whey protein hydrolysate is described which is free of allergenics while preserving the structures susceptible of exerting anticipatory regulations to maximize the tolerance and protein...
5776724 Chaperonin-mediated protein folding  
The mechanisms and components required for chaperonin-dependent folding of proteins has been elucidated using the groEL and groES proteins of E. coli to reconstitute enzymatic activity of two...
5770699 Process for production of inhibited forms of activated blood factors  
A process for producing a highly purified preparation of an inhibited form of an activated blood factor entails providing a partially purified preparation containing the blood factor of interest,...
5763157 Biological reagent spheres  
A reagent sphere is disclosed comprising at least one biological reagent and a glass-forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition,...
5763215 Method of removing N-terminal amino acid residues from eucaryotic polypeptide analogs and polypeptides produced thereby  
A method of sequentially removing one or more N-terminal amino acid residues from an analog of a eucaryotic polypeptide synthesized in a foreign host, comprises contacting the eucaryotic...
5753283 Method for stabilizing rice bran and rice bran products  
A process for stabilizing rice bran containing protein and a naturally occurring lipase enzyme that causes rancidity. The rice bran is treated with an antilipase enzyme, preferably a nonspecific...
5753236 Antigenic composition obtained by V8 proteolysis of a protein from S. mansoni  
An antigenic composition against S. mansoni comprising an 8 kD peptidic fragment associated with a suitable vehicle, the 8 kD peptidic fragment being obtained by controlled proteolysis using V8...
5750360 Method for quantitatively measuring apoptosis  
The invention encompasses methods of detecting and/or quantifying ε(γ-glutamyl)lysine isodipeptide by catalytically releasing lysine, then measuring free lysine.
5741664 Subtilisin variants capable of cleaving substrates containing dibasic residues  
The bacterial serine protease, subtilisin BPN', has been mutated so that it will efficiently and selectively cleave substrates containing dibasic residues. A combination mutant, where Asn 62 was...
5739023 Stabilized neutral metalloprotease composition, a method of making the composition, and a method of transporting the composition  
A method for making a stabilized neutral metalloprotease enzyme composition is described in which a neutral metalloprotease and an aqueous solution are combined to obtain a solution or slurry...
5736356 Transglutaminase originating from Crassostrea gigas  
The present invention relates to a transglutaminase originating from Crassostrea gigas, a gene coding for the transglutaminase, a plasmid carrying the gene, a microorganism transformed with the...
5733742 Production of antibody fragments from whole blood  
A method of preparing polyclonal immunoglobulin Fab fragments comprising cleaving immunoglobulin molecules, characterised in that the said cleavage is carried out on immunoglobulins in blood,...
5728544 Protease II  
A modified protease is disclosed, which is a mutant of the thermostable neutral metallo-protease having the amino acid sequence of SEQ ID NO:1 wherein the 150th aspartic acid residue is replaced...
5728543 Clostripain catalyzed hydrolysis of preproinsulin analogs into corresponding insulins  
A process is described to specifically hydrolyze the amino acid chain of preproinsulin analogs to give the corresponding insulins. The hydrolysis is catalyzed by clostripain and, if necessary,...
5726033 Process for preparing proteins from protein-containing substance  
In a process for preparing proteins from a protein-containing substance, the substance is dispersed in an alkaline solvent with a pH of over 11.5 and at a temperature of under 30° C. The proteins...
5726034 Aglucone isoflavone enriched vegetable protein extract and protein material, and high genistein and daidzein content materials and process for producing the same  
An aglucone is isoflavone enriched vegetable protein extract and protein material are provided, as well as a high genistein content material and a high daidzein content material. Isoflavone...
5723443 Lipid metabolism promoting agent and its use  
The invention concerns a low molecular weight proteinaceous agent which can be used to reduce body fat content by suppressing fat digestion and absorption thus reducing body fat and limiting...
5719039 Enzyme-surfactant ion-pair complex catalyzed reactions in organic solvents  
Organic enzyme solutions comprise an ion pair complex of an enzyme and a surfactant, and an organic solvent in which the enzyme-surfactant ion pair is dissolved. The solution has catalytic...
5716801 Method for production of a vegetable protein hydrolyzate with proteases  
A well tasting and organoleptically acceptable vegetable protein hydrolyzate such as soy, pea or rice protein hydrolyzate is produced in high yield by a method using a combination of non-pH-stat...
5714344 Protease-derivatized CVF  
A novel functionally active derivative of cobra venom factor is described in which the β-chain has been cleaved by treatment with a protease. Gel electrophoretic analyses of the purified...
5711853 Paper strengthened with solubilized collagen and method  
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
5710014 Cloned cDNA for human procathepsin l.  
A cloned cDNA containing complete coding sequence for the expression of a protein with all properties of the precursor to human procathepsin L is described. All of the protein's major domains,...
5695952 Method for producing Leu13 !motilin  
A novel motilin analog peptide containing leucine instead of the usual 13th amino acid methionine, as in the naturally occurring motilin, is produced by gene recombination techniques in which...
5693485 Enzymatic coupling reaction of N-protected-L-aspartic acid and phenylalanine methyl ester  
The invention relates to a process for the preparation of N-protected-L-aspartyl-L-phenylalanine methyl ester by enzymatic coupling of an N-protected-L-aspartic acid and L- or DL-phenylalanine...
5691152 Stable avidin composition  
Compositions and methods for avidin immobilized on an inert support material, e.g., agarose, are disclosed. The compositions have high activity levels of avidin and may further include a bulking...
5691165 Method for production of a whey protein hydrolyzate  
A well tasting and organoleptically acceptable whey protein hydrolyzate is produced in high yield by a method using a combination of non-pH-stat hydrolysis and ultrafiltration. Preferably, the...
5686262 Recycle process for the production of low-cost soluble collagen  
The invention includes a method that provides a low cost aqueous solution of solubilized collagen by the steps of: (a) providing an aqueous ground slurry of insoluble collagen and adjusting the pH...
5681586 Enzyme-modified soy and soy/casein combination healing compositions  
A pharmaceutical composition comprising an improved modified protein sol is used for treating and enhancing the healing of arthritis and cutaneous acne. Prior to being modified, a protein is...
5679539 Oxidized polyethylene or polypropylene particulate supports  
Polyolefin particles are chemically modified by oxidation to provide a large surface area and high loading. The particles result in low back pressure in column systems, and are economical to...
5670340 Process for producing peptides in E. coli  
The present invention is a process to express a target peptide in a large amount and accumulate the target peptide in host cells in the form of inclusion bodies. The process comprises: A)...
5670332 Enzymatic reactions and apparatus for carrying them out  
A water-supported enzymatic reaction is carried out with the substrate and the enzyme present in the solid phase. Either the water does not form a liquid continuum around substrate and enzyme, or...
5670369 Method for the production of soluble collagen  
The invention includes an improved method for producing an aqueous solution of soluble collagen. The method comprises the steps of: (A) providing an aqueous ground slurry of insoluble collagen...
5665563 Coupled transcription and translation in eukaryotic cell-free extract  
A method for producing protein from DNA in a static reaction in which DNA, ribonucleotide triphosphates, magnesium and a RNA polymerase are mixed and incubated during which RNA is transcribed from...
5663058 Process for producing soybean protein material  
There is disclosed a process for producing a soybean protein material which comprises the steps of: hydrolyzing soybean protein with a protease in an aqueous system to an extent of hydrolysis of 5...
5663291 Process for obtaining insulin having correctly linked cystine bridges  
A process for obtaining insulin having correctly linked cystine bridges from a corresponding proinsulin amino acid chain in the presence of mercaptan, chaotropic auxiliaries and at a pH of 10 to...
5661126 Use of mullerian inhibiting substance for treating certain tumors and for modulating class I major histocompatibility antigen expression  
This application concerns the treatment of certain tumors using an effective amount of the glycoprotein Mullerian Inhibiting Substance (MIS). This application further concerns the treatment of...
5658754 Cell-free synthesis and isolation of novel genes and polypeptides  
A method for the cell-free synthesis and isolation of novel genes and polypeptides is provided. Within one embodiment, an expression unit is constructed onto which semi-random nucleotide sequences...
5658753 Catalytic antibody components  
Catalytic antibody components, methods for producing catalytic antibody components, methods for using catalytic antibody components, in particular, single chain and smaller components are...
5656450 Activation of latent transforming growth factor β by matrix vesicles  
A latent growth factor such as transforming growth factor beta (TGFβ) is converted to active form by matrix vesicles or an extract from matrix vesicles. The matrix vesicles may be stimulated with...
5654166 Process of preparing hormone-free bovine cartilage for dosage form  
The present invention relates to a significant improvement in the preparation of a pharmaceutically purified and proven effective product of powdered bovine tracheal cartilage for the treatment of...
5654150 Method of expression cloning  
The present invention provides improvements in the expression cloning method for isolating novel cDNA clones. In particular, in the expression cloning method comprising the steps of preparing a...
5647957 Method of preparing paper strengthened with solubilized collagen  
A method for making a collagen strengthened cellulosic sheet by providing a cellulosic pulp slurry; adding solubilized collagen to the pulp slurry, and mixing for a time effective for interaction...
5643744 Method for producing polypeptide  
The present invention provides a method for producing a polypeptide, which comprises condensing precursors comprising an amino acid and an adaptor in the presence of ribosomes, rRNAs, a larger...
5641646 Process for preparation of human glicentin  
Disclosed is a process for the preparation of native human glicentin, which comprises producing by gene technology a fused protein composed of human glicentin having a peptide moiety connected to...