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RE40938 Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof  
A method of isolating, purifying and recrystallizing substantially pure lutein, preferably from saponified marigold oleoresin in its pure free form, apart from chemical impurities and other...
RE40931 Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof  
A method of isolating, purifying and recrystallizing substantially pure lutein, preferably from saponified marigold oleoresin in its pure free form, apart from chemical impurities and other...
7595171 Ketocarotenoids from Adonis palaestina  
Methods for the production of new Adonis palaestina plants and plant populations with improved characteristics such as increased flower size, astaxanthin content, and/or reduced cardenolide...
RE40912 Process for isolation, purification, and recrystallization of lutein from saponified marigold oleoresin and uses thereof  
A method of isolating, purifying and recrystallizing substantially pure lutein, preferably from saponified marigold oleoresin in its pure free form, apart from chemical impurities and other...
7566795 Preparation of retinyl esters  
Long-chain esters of retinol are prepared via a chemoenzymatic process from short-chain retinyl esters and an appropriate long-chain acid or ester in the presence of an enzyme. Use of various...
7566551 Method of producing xanthophyll  
The present invention provides a method for producing a xanthophyll from a photosynthetic microalga, which includes inoculating a photosynthetic microalga containing a xanthophyll, preferably an...
7504236 Method to increase carotenoid production in a microbial host cell by down-regulating glycogen synthase  
A method to increase carotenoid production in carotenogenic microbial host cells is provided by down-regulating or disrupting glycogen synthesis. Disruption of glycogen synthase activity in a...
7459288 Method of producing retinyl esters  
A method of producing a retinyl ester compound comprising subjecting a composition comprising retinyl or a retinyl ester and a fat or oil of animal or vegetable origins to enzyme catalysed...
7432076 Astaxanthin production using fed-batch fermentation process by Phaffia rhodozyma  
Disclosed is a fermentation method of astaxanthin using Phaffia rhodozyma comprising the steps of: (a) in the growing phase, feeding of a nutrient medium containing glucose or sucrose based on the...
7422873 Mutant carotenoid ketolase  
CrtW carotenoid ketolases are provided useful for the production of astaxanthin. The ketolases genes of the present invention exhibit improved ketolase activity when converting cyclic hydroxylated...
7413872 Device for preparing specimens for a cryo-electron microscope  
The invention relates to a device for preparing specimens for a cryo-electron microscope, comprising an environmental chamber, a holder for a sample or a carrier, and at least one blotting element...
7393671 Mutant carotenoid ketolases  
CrtW carotenoid ketolases are provided that are useful for the production of astaxanthin and other cyclic ketocarotenoids. The mutant ketolase genes of the present invention encode polypeptides...
7381541 Methods for producing animal feed preparations with astaxanthin-containing plants or parts of plants of the genus Tagetes  
The present invention relates to the use of astaxanthin-containing plants or parts of plants of the genus Tagetes or astaxanthin-containing extracts of astaxanthin-containing plants or parts of...
7374908 Microorganism and production of carotinoid compounds thereby  
It is intended to provide a process for conveniently and efficiently producing large amounts of astaxanthin and canthaxanthin from a material which can be easily obtained. A microorganism ...
7288395 ACC gene  
The present invention relates to a gene useful in a process to increase the microbial production of carotenoids. The carotenoids astaxanthin is distributed in a wide variety of organisms such as...
7288387 Genes of strain DC413 encoding enzymes involved in biosynthesis of carotenoid compounds  
A carotenogenic biosynthetic gene cluster has been isolated from Panteoa stewartii strain DC413, wherein the genetic organization of the cluster is crtE-idi-crtX-crtY-crtI-crtB-crtZ. The genes...
7252965 Method of production of β-carotene by fermentation in mixed culture using (+) and (−) strains of Blakeslea trispora  
The invention consists of fermenting selected strains of Blakeslea trispora in conditions such that β-carotene is produced in the form of stabilized preparations with residual contents of other...
7252964 Isolated carotenoid biosynthesis gene cluster involved in canthaxanthin production and applications thereof  
Isolated gene cluster involved in canthaxanthin biosynthesis, which comprises a polynucleotide wherein: crtY, crtI, crtB and crtW genes are clustered in this order and in the same...
7232666 Optimized bacterial host strains of Methylomonas sp. 16a  
Methanotrophic bacterial strains are provided that have been optimized for the production of carotenoid compounds through the down-regulation of one or more of the crtN1, ald, crtN2 and crtN3 genes...
7232665 Mutations affecting carotenoid production  
Mutations in genes having no direct relationship to the carotenoid biosynthetic pathway have been found to increase carbon flux through that pathway. Complete disruption in the deaD, mreC, and yfhE...
7229786 Method of producing purified carotenoid compounds  
A method of producing a carotenoid in solid form includes culturing a strain of Chlorophyta algae cells in a minimal inorganic medium and separating the algae comprising a solid form of carotenoid....
7229784 Modulation of secondary metabolite production by zinc binuclear cluster proteins  
Methods for improving the production of a secondary metabolite by a fungus by increasing the yield or productivity of the secondary metabolite produced by the fungus are described. The methods...
7205123 Recombinant materials for carotenoid production  
The present invention provides recombinant DNA comprising a transcription promoter and a downstream sequence to be expressed, in operable linkage therewith, wherein the transcription promoter...
7192731 Methods for efficient extraction of carotenoids using an esterase  
A method of increasing a fraction of free carotenoids in a source of carotenoids in which at least some of the carotenoids are fatty acid esterified carotenoids is disclosed. The method is effected...
7186523 Method for synthesis of aryl-carotenoids  
A method for the production of aryl-carotenoids is provided through bioconversion of cyclic carotenoids having at least one β-ionone ring. Expression of a heterologous gene encoding a carotene...
7183089 Method for enhancing production of isoprenoid compounds  
The present invention provides methods of producing an isoprenoid or an isoprenoid precursor in a genetically modified host cell. The methods generally involve modulating the level of...
7163819 Bacterial hemoglobin genes and their use to increase carotenoid production  
Genes encoding bacterial oxygen binding proteins are provided. Recombinant expression of at least one of the present bacterial hemoglobin genes increased the growth characteristics and/or...
7132257 Production or aromatic carotenoids in gram negative bacteria  
A method for the in vivo bioconversion of cyclic carotenes having a β-ionone ring to the corresponding aryl carotene is provided. Gram negative host cells expressing a heterologous,...
7122341 Engineering of metabolic control  
The invention features a method of producing heterologous molecules in cells under the regulatory control of a metabolite and metabolic flux. The method can enhance the synthesis of heterologous...
7105634 Genetic constructs encoding carotenoid biosynthetic enzymes  
Genes isolated from Methylomonas sp. 16a have been determined to play a role in the carotenoid biosynthetic pathway. Specifically, crtN2 gene has the ability to produce omega-aldehyde functional...
7098000 Method for production of C30-aldehyde carotenoids  
The present invention provides methods to engineer microorganisms for the production of C 30 -aldehyde carotenoids. Specifically, various combinations of crtM, sqs, crtN and crtN2 genes from ...
7087403 Biological production of tetradehydrolycopene  
Mutant phytoene desaturase genes are provided encoding polypeptides having the ability to convert a phytoene desaturase substrate to tetradehydrolycopene. Both in vivo and in vitro methods are...
7074588 Carotenoid ketolase gene  
A ketolase gene has been isolated from Rhodococcus erythropolis AN12 strain encoding a carotenoid modification enzyme of the carotenoid biosynthetic pathway. The gene and gene product are the...
7074587 Astaxanthin synthase  
The present invention is directed to genetic materials useful for the preparation of astaxanthin from beta-carotene, such as polypeptides having astaxanthin synthase activity, DNA fragments coding...
7070952 Genes encoding carotenoid compounds  
Genes have been isolated from Pectobacterium cypripedii encoding geranylgeranyl pyrophosphate (GGPP) synthase (CrtE), phytoene synthase (CrtB), phytoene desaturase (Crtl), lycopene cyclase...
7063957 Methods for production of astaxanthin from the green microalgae Chlorella in dark-heterotrophic cultures  
A method for producing the high-value ketocarotenoid astaxanthin by the green microalga Chlorella zofingiensis in dark-heterotrophic cultures shows excellent growth and high-yield astaxanthin...
7063956 Fermentative carotenoid production  
Novel proteins of microorganism E-396 (FERM BP-4283) and the DNA sequences which encode these proteins have been discovered to provide an improved biosynthetic pathway from farnesyl pyrophosphate...
7063955 Method for production of asymmetric carotenoids  
Genes have been isolated from Rhodococcus and Deinococcus which encode a specific lycopene β-cyclase capable of converting acyclic carotenoids with at least one ψ-end group to the...
7056717 Genes involved in isoprenoid compound production  
Genes have been isolated from Methylomonas 16a sp. encoding the isoprenoid biosynthetic pathway. The genes and gene products are the first isolated from a Methylomonas strain that is capable of...
7041471 Carotene hydroxylase and method for producing xanthophyll derivatives  
The present invention relates to proteins which have an enzymatic activity for converting β-carotene into zeaxanthin or canthaxanthin into astaxanthin, to nucleic acids which encode these...
7015014 Isolation of carotenoid crystals  
The present invention relates to a crystalline carotenoid compound, such as β-carotene, with a purity of at least 95% and with substantially no solvent enclosed in the crystal lattice. The present...
6969595 Carotenoid production from a single carbon substrate  
A method for the production of carotenoid compounds is disclosed. The method relies on the use of microorganisms which metabolize single carbon substrates for the production of carotenoid compounds...
6936459 Medium for the production of betacarotene and other carotenoids from dunaliella salina (ARL 5) and a strain of dunaliella salina for production of carotenes using the novel media  
The invention relates to the development of a novel medium starting from fresh water using a salt solution complex comprising a non conventional salt, namely KCl and conventional salts such as NaCl...
6929928 Genes encoding carotenoid compounds  
A unique carotenogenic biosynthetic gene cluster has been isolated from Panteoa agglomerans strain DC404, wherein the genetic organization of the cluster is crtE-idi-crtY-crtI-crtB-crtZ. The...
6872556 Isoprenoid production  
The present invention relates to an isolated DNA sequence encoding an enzyme (e.g., farnesyl pyrophosphate synthase) in the pathway from isopentenyl pyrophosphate to farnesyl pyrophosphate. Vectors...
6869773 Process for the manufacture of carotenoids and biologically useful materials thereof  
A process is provided for producing a carotenoid, which process includes cultivating a recombinant organism having a gene for one or more active oxygen species-quenching factor(s) that is...
6825002 Process for producing carotenoid pigments  
The present invention provides a method for changing production ratios of carotenoid compounds in a process of microbiological production of a plurality of carotenoid compounds. By controlling the...
6821749 Methods of producing carotenoids using DNA molecules encoding isopentenyl pyrophosphate isomerase  
The production of carotenoid is accomplished using a DNA molecule that encodes a polypeptide as obtained from Haematococcus pluvialis, Phaffia rhodozyma, or Saccharomyces cerevisiae, having...
6818798 Process for making a (3R,3′R)-zeaxanthin precursor  
A process for the conversion of (3R,3′R,6′R)-lutein to 3′-epilutein, a carotenoid precursor for industrial production of naturally occurring (3R,3′R)-zeaxanthin, is disclosed.
6812001 Isolation of carotenoid crystals from microbial biomass  
A process for the isolation of crystalline carotenoid compound from microbial biomass comprising disrupting the microbial cell walls, separating cellular debris from the carotenoid-containing...
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