|
Match
|
Document |
Document Title |
|
|
7605144 |
Enzyme catalyzed therapeutic compounds
This invention provides novel compounds selected from the group consisting of a 1,5-substituted pyrimidine derivative or analog and substituted furano-pyrimidone analogs. The compounds are useful...
|
|
|
6750040 |
Cell-free synthesis of polyketides
Cell-free systems which effect the production of polyketides employing modular polyketide synthases are described. Libraries of new and/or known polyketides may also be produced in cell-free...
|
|
|
6288272 |
Continuous process for preparing optically pure (s)-3,4-dihydroxybutyric acid derivatives
The present invention relates to a continuous process for preparing optically pure (S)-3,4-dihydroxybutyric acid derivatives expressed by the following Formula 1 and more particularly, to the...
|
|
|
6261766 |
Detection of prostate-specific antigen in breast tumors
This invention relates to the detection of prostate-specific antigen (PSA) in female breast tumor extract as a prognostic or predictive indicator for breast carcinoma. The presence of...
|
|
|
6232443 |
Renal nuclear matrix proteins, polynucleotide sequences encoding them, and their use
Nuclear matrix proteins (NMP) are useful markers in diagnosing and monitoring the stage of malignancy of a cell, and in treating cell proliferative disorders associated with the NMP.
|
|
|
6080555 |
Synthesis of polyketides from diketides
Cell-free systems which effect the production of polyketides employing modular polyketide synthases are described. Libraries of new and/or known polyketides may also be produced in cell-free...
|
|
|
5989903 |
Strain for the production of 6-dimethyltetracycline, method for producing the strain and vector for use in the method
Recombinant S. aureofaciens cells are provided. These cells comprise: (a) at least one CTC 11 gene; and (b) optionally (i) a CTC 09 gene; (ii) a CTC 03 gene; or (iii)a combination...
|
|
|
5965429 |
Strain for the production of 6-demethyltetracycline, method for producing the strain and vector for use in the method
Recombinant S. aureofaciens cells are provided. These cells comprise: (a) at least one CTC 11 gene; and (b) optionally (i) a CTC 09 gene; (ii) a CTC 03 gene; or (iii) a combination...
|
|
|
5925531 |
Human bone marrow endothelial cell line and methods of use thereof
The present invention provides immortalized human bone marrow endothelial cells which are useful for the study of tumor metastasis. In particular, the human bone marrow endothelial cell lines...
|
|
|
5776748 |
Method of formation of microstamped patterns on plates for adhesion of cells and other biological materials, devices and uses therefor
The disclosed invention is a device for adhering cells in a specific and predetermined position. The device comprises a plate defining a surface and a plurality of cytophilic islands that adhere...
|
|
|
5217877 |
Process for the preparation of α-glucosidase inhibitor, pradimicin Q
The present invention relates to a novel α-glucosidase inhibitor, pradimicin Q, having the following formula ##STR1## and its pharmaceutically acceptable base salts.
|
|
|
5183758 |
Production of 7-chloro-3-methoxy-2'-N-methyltetracycline with Actinomadura brunnea
An antibiotic complex is produced by the microorganism, Actinomadura brunnea NRRL 15216, ATCC 39216. A novel antibiotic 7-chloro-8-methoxy-2'-N-methyltetracycline, isolated from the antibiotic...
|
|
|
5100921 |
Angucyclinones from Streptomycetes, a process for the preparation thereof, and the use thereof
New angucyclinones with a therapeutic action can be prepared with the aid of a strain of the genus Streptomyces.
|
|
|
5066585 |
Method of inhibiting fungus using novel antifungal compounds
A new species of Micromonospora, in particular Micromonospora spartanea ATCC 53803, is described. The species produces antifungal compounds spartanamicins A and B. Methods for the production,...
|
|
|
4752605 |
7-chloro-4a-hydroxy-8-methoxytetracycline, antibiotic compositions containing them and a method of using
The antibiotic 7273 complex is elaborated by the microorganism, Dactylosporangium vescum ATCC 39499. The novel 7-chloro-4a-hydroxy-8-methoxytetracycline isolated from antibiotic 7273 complex is...
|
|
|
4385122 |
Anthracycline antibiotics produced by streptosporangium fragile
A novel anthracycline antibiotic complex, fragilomycin complex, is produced by the cultivation of a fermentation broth containing Streptosporangium fragile Shearer sp. nov. ATCC 31519...
|
|
|
4116769 |
Process for preparing 7-deoxysteffimycinol
Bioconversion of the antibiotic steffimycinone to the antibiotic steffimycinol. Steffimycinol is active against various microorganisms, for example, Bacillus subtilis, Mycobacterium avium and...
|
|
|
4106994 |
Process for producing steffimycinol
Bioconversion of the antibiotic steffimycinone to the antibiotic steffimycinol. Steffimycinol is active against various microorganisms, for example, Bacillus subtilis, Mycobacterium avium and...
|
|
|
4077844 |
Process for preparing steffimycinol
Bioconversion of the antibiotic steffimycinone to the antibiotic steffimycinol. Steffimycinol is active against various microorganisms, for example, Bacillus subtilis, Mycobacterium avium and...
|
|
|
4071411 |
Antitumor antibiotics aclacinomycins A and B [RD-9187A]
New antitumor agents named aclacinomycins A and B, which are anthracycline glycosides and inhibit the growth of various microorganisms e.g., Staphylococcus aureus, Micrococcus flavus,...
|
|
|
4013515 |
Process for the preparation of the antibiotic 20.798 R.P.
20,798 R.P., which has valuable anti-tumor properties, and acid addition salts thereof are prepared by the microbiological reduction of daunorubicin of the formula: ##SPC1## Or of an acid addition...
|
|
|
3886046 |
Recycle fermentation process
A fermentation process is disclosed which comprises destroying or partially destroying the fermenting cells and utilizing said cells as nutrients by recycling in the presence of the desired...
|
|
|
3639214 |
PRODUCTION OF 6-DEMETHYLTETRACYCLINE
This invention relates in an improved method for manufacturing antibiotics of the tetracycline group by growing a micro-organism of the class consisting of Streptomyces aureofaciens NC1B 9501,...
|
|
|
3637463 |
PRODUCTION OF OXYTETRACYCLINE USING STREPTOMYCES ALBOFLAVUS (ATCC 15388)
A fermentative process for the production of oxytetracycline which comprises fermenting a nutrient broth under aerobic conditions at a temperature between 22° and 30° C. by a mutant of...
|
|
|
3616239 |
7-CHLORO-6-DEMETHYL-TETRACYCLINE FERMENTATION
This disclosure describes a process for the production of 7-chloro-6-demethyltetracycline by fermentative biosynthesis using strains of Streptomyces aureofaciens which impart a color to their whole...
|
|
|
3616241 |
PROCESS FOR THE PRODUCTION OF 7-CHLORO-5 ,11 -DEHYDROTETRACYCLINE
This disclosure describes a process of producing 7-chloro-5a,11a-dehydrotetracycline which comprises cultivating, under submerged aerobic conditions, strains of Streptomyces aureofaciens which are...
|
|
|
3516909 |
FERMENTATIVE BIOSYNTHESIS OF TETRACYCLINE ANTIBIOTICS
|
|
|
3463791 |
7-CHLORO-4-DEDIMETHYLAMINO-12,12ALPHA-SECOTETRACYCLINE-12-OIC ACID-6,12-LACTONES
|
|
|
3462487 |
CHEMICAL COMPOUNDS AND METHODS FOR PREPARING THE SAME
|
|
|
3434930 |
METHOD OF PRODUCING TETRACYCLINE
|
|
|
3433709 |
BIOLOGICAL TRANSFORMATION OF ALPHA-6-DEOXYTETRACYCLINES TO TETRACYCLINES
|
|
|
3433710 |
PROCESS FOR THE PREPARATION OF 7-CHLORO-5-HYDROXYTETRACYCLINE
|
|
|
3432394 |
FERMENTATIVE PRODUCTION OF TETRACYCLINE
|
|
|
3429780 |
FERMENTATION PROCESS FOR THE PRODUCTION OF TETRACYCLINE
|
|
|
3429781 |
PROCESS FOR THE PRODUCTION OF TETRACYCLINE
|
|
|
3425911 |
METHOD OF PRODUCING TETRACYCLINE
|
|
|
3423398 |
SANGIVAMYCIN AND DERIVATIVES THEREOF
|
|
|
3409616 |
4-oxo-10-hydroxy-1, 2, 3, 4-tetrahydroanthracene-2-(alpha-amino)acetates
|
|
|
3408258 |
Process for producing oxytetra-cycline antibiotic
|
|
|
3401088 |
Process of fermentation of chlortetracycline and tetracycline antibiotics
|
|
|
3400050 |
PREPARATION AND ISOLATION OF TETRACYCLINES WITH THE AID OF TETRACYCLINE COMPLEXES
|
|
|
3398057 |
Process for producing tetracycline
|
|
|
3390055 |
Fermentative production of nu-ethyloxytetracycline
|
|
|
3385765 |
Novel process of producing 1, 3, 4, 10, 11, 12-hexahydroxy-6-methylnaphthacene-2-carboxamide
|
|
|
3375276 |
Method for preparing tetracycline products
|
|
|
3364123 |
Production of 4n-demethyl-4n-ethyl tetracyclines
|
|
|
3364260 |
4n-demethyl-4n-ethyl tetracyclines
|
|
|
3317403 |
Streptomyces aureofaciens fermentation process using glyceride oil and casein
|
|
|
3317404 |
Production of metabolic products of gram-positive bacteria and streptomyces by the addition of kinetin to the fermentation broth
|
|
|
3298927 |
Process for preparing 6-demethyltetracyclines using ethionine sulfoxide
|