|
Match
|
Document |
Document Title |
|
|
7620502 |
Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedure
In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination.
|
|
|
7619079 |
Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof
The present invention relates to identification of a receptor for a satiety factor, which is involved in body weight homeostasis. Mutations in this receptor are associated with obese phenotypes. In...
|
|
|
7618947 |
Modulation of HIF-1 beta expression
Compounds, compositions and methods are provided for modulating the expression of HIF1-beta. The compositions comprise oligonucleotides, targeted to nucleic acid encoding HIF1-beta. Methods of...
|
|
|
7618795 |
Starch process
The present invention relates to a process for enzymatic hydrolysis of granular starch into a soluble starch hydrolysate at a temperature below the initial gelatinization temperature of said...
|
|
|
7618781 |
Nucleic acids for detecting B-cell malignancy
This document provides methods and materials related to detecting gene rearrangements (e.g., MYC gene rearrangements). For example, nucleic acid probe sets for detecting MYC-immunoglobulin gene...
|
|
|
7618780 |
Use of mass labelled probes to detect target nucleic acids using mass spectrometry
The invention relates to the use of mass labelled probes to characterize nucleic acids by mass spectrometry. Thus the invention provides methods of detecting the presence of a target nucleic acid...
|
|
|
7618779 |
Chromosome 1p36 polymorphisms and low bone mineral density
The invention provides methods and compositions for diagnosing risk of low BMD and risk of osteoporosis based on the detection of SNP identity for human chromosome 1p36 polymorphisms designated in...
|
|
|
7618778 |
Producing, cataloging and classifying sequence tags
The described method provides, methods, and kits to produce, identify, catalog and classify a comprehensive collection of nucleic acid targets produced from a nucleic acid sample. The method,...
|
|
|
7618777 |
Composition and method for array hybridization
The present disclosure relates to a system, composition, and method for hybridizing a microarray. The composition includes a superwetting agent. The method includes contacting the microarray with...
|
|
|
7618776 |
Rolling circle replication reporter systems
Disclosed are compositions and a method for of amplifying nucleic acid sequences useful for detecting the presence of molecules of interest. The method is useful for detecting specific nucleic...
|
|
|
7618775 |
Expanding the eukaryotic genetic code
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include...
|
|
|
7618774 |
Materials and methods for identifying genes and/or agents that alter replicative lifespan
Recombinant materials, including DNA constructs, expression vectors, and host cells, and methods of identifying an environmental stimulus or a gene that alters the lifespan of an organism are...
|
|
|
7618773 |
Headloop DNA amplification
A method for the selective amplification of a target nucleic acid in a sample comprising the target nucleic acid and at least one non-target nucleic acid, the method comprising amplifying the...
|
|
|
7618772 |
Methods and compositions for diagnosing and suppressing metastasis thereof
Disclosed is a method for determining metastatic potential of tumors, a method and a composition for treating/suppressing metastasis of cancers, as well as a method for obtaining a metastasis...
|
|
|
7617054 |
Method and apparatus for analysing nucleic acid sequence
A method of analyzing nucleic acid sequence data produced by automated sequencer comprises scaling the data according to a map of relative heights of homozygous base data. An apparatus for...
|
|
|
7616790 |
Histological assessment of nuclear pleomorphism
A method of histological assessment of nuclear pleomorphism to identify potential cell nuclei divides image data into overlapping sub-images. It uses principal component analysis to derive...
|
|
|
7615681 |
Methods for modifying plant responses to stress and correspondingly derived plants
Plant stresses such as pest drought, and excessive temperatures can lead to significant losses of crops each year. There is a continuing need to develop novel plant varieties that are less...
|
|
|
7615646 |
Chiral indole intermediates and their fluorescent cyanine dyes containing functional groups
This invention relates to the functionalized cyanine dyes and more particularly, to the synthesis of chiral 3-substituted 2,3′-dymethyl-3H-indole and its derivatives as intermediates for...
|
|
|
7615626 |
Methods, agents, and compound screening assays for inducing differentiation of undifferentiatied mammalian cells into osteoblasts
The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a...
|
|
|
7615621 |
High lysine maize compositions and methods for detection thereof
Disclosed herein are assays for detecting the presence of a lysine-increasing transgenic event based on the DNA sequence of the exogenous DNA construct inserted into the maize genome and of genomic...
|
|
|
7615620 |
Detection system for PCR assay
The present invention provides a detection system for a PCR process using FRET which comprises at least two single-labelled Oligonucleotide sequences of differing Tm that hybridize to one another...
|
|
|
7615540 |
Formulations comprising antisense nucleotides to connexins
A therapeutic and/or cosmetic formulation comprising at least one anti-sense polynucleotide to a connexin protein together with a pharmaceutically acceptable carrier or vehicle is useful in site...
|
|
|
7615529 |
Methods and compositions for modulating hyperstabilized c-met
The invention provides methods and compositions for modulating the HGF/c-met signaling pathway, in particular by inhibiting a hyperstabilized c-met protein.
|
|
|
7615369 |
Reconfigurable protein patterning using electrowetting microelectrodes
A protein patterning electrode device consisting of capacitor microelectrode arrays coated with a protein non-adherent layer is provided. Operation of the electrode is based on a phenomenon called...
|
|
|
7615353 |
Tivozanib response prediction
A diagnostic method for predicting quantitatively whether a human tumor will be responsive or resistant (non-responsive) to treatment with the VEGF inhibitor, tivozanib (AV-951), is disclosed. The...
|
|
|
7615352 |
Detection of Epstein-Barr virus
The invention provides methods to detect EBV in biological samples using real-time PCR. Primers and probes for the detection of EBV are provided by the invention.
|
|
|
7615351 |
Two stage nucleic acid amplification using an amplification oligomer
This invention provides methods, compositions and systems to detect a nucleic acid of interest in a two-stage amplification. The two-stage amplification begins with a first non-enzymatic...
|
|
|
7615350 |
Methods for haplotyping genomic DNA
The present invention provides a novel method for specifically isolating and separating large segments of genomic DNA that can subsequently be used to determine a genomic haplotype. The invention...
|
|
|
7615349 |
Melanoma gene signature
Methods and compositions for evaluating gene expression in melanoma samples are provided herein.
|
|
|
7615348 |
Electrochemical method to measure DNA attachment to an electrode surface in the presence of molecular oxygen
The present disclosure provides methods and compositions for conducting an assay to detect a polynucleotide. In particular, ruthenium complexes having reduction potentials that do not coincide with...
|
|
|
7615347 |
Method for trapping nucleic acids using divalent metal ions
A method for trapping nucleic acids on a surface of a solid phase substrate, which comprises the step of contacting a sample containing nucleic acids and having a pH of 12 or higher with the...
|
|
|
7615346 |
Rapid and efficient capture of DNA from sample without using cell lysing reagent
Nucleic acids can be made available for amplification or other treatment after admixture of a sample with specific weakly basic polymers to form a precipitate with the nucleic acids at acidic pH....
|
|
|
7615345 |
Arrays formed of encoded beads having oligonucleotides attached
A method and apparatus for the manipulation of colloidal particles and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution....
|
|
|
7615344 |
Process for producing extract for cell-free protein synthesis and cell extract produced thereby
It is intended to provide a process for producing an extract for cell-free protein synthesis whereby the productivity of a protein and the production efficiency can be improved. Cells are cultured...
|
|
|
7615343 |
Electrical readout of the binding of analyte molecules to probe molecules
The invention relates to the detection of the binding of analyte molecules, for example biopolymer molecules, to immobilized capture substance molecules. The invention consists in using...
|
|
|
7615342 |
ACTN3 genotype screen for athletic performance
The present invention concerns novel methods of selecting or matching a sport or sporting event to an individual (e.g. a sprint/power sport or an endurance sport) and predicting athletic...
|
|
|
7615341 |
Disease susceptibility gene for rheumatoid arthritis, protein thereof, evaluation method and evaluation kit for evaluating onset possibility of rheumatoid arthritis by using those, and remedy and curing medicine for rheumatoid arthritis
An gene was identified as a RA disease susceptibility gene on Human Chromosome 8, the gene coding a protein that has an amino acid sequence shown in SEQ. ID NO. 1 and that has such mutation that...
|
|
|
7615340 |
Electronic detection of interaction and detection of interaction based on the interruption of flow
Porous members can be positioned so as to partially or fully span channels in microfluidic systems. The porous members can be assembled and/or disassembled in situ. The porous members can be made...
|
|
|
7613571 |
Method and system for the multidimensional morphological reconstruction of genome expression activity
A method of morphological reconstruction of biological activity in a tissue sample maps biological data resulting from analysis of tissue samples onto a 3-D morphological rendering of the...
|
|
|
7612190 |
Method for targeting a polypeptide onto cellular surface
The present invention relates to a polypeptide having an activity for targeting a heterogeneous polypeptide to a surface of cytoplasmic membrane, a nucleic acid encoding the polypeptide, a...
|
|
|
7612187 |
2-azapurine compounds and their uses
Within oligonucleotides 2-azapurine and especially 2-azaadenine bases form specifically base pairs with guanine. This base pair is of analogous stability as an adenine-thymine but less stable than...
|
|
|
7612185 |
Nucleic acid biosensors
Sensors comprising aptazymes capable of detecting the presence and concentration of effectors, as well as methods of using such sensors, are disclosed.
|
|
|
7611902 |
Diagnostic method for myopathy
This invention provides a diagnostic method for determining statin induced myopathy. The method is especially applicable for determining warnings, early signs and also symptomatic myopathy. The...
|
|
|
7611889 |
Method for noncovalently immobilizing a biomolecule on a solid substrate and microarray produced according to the method
Provided is a method for noncovalently immobilizing a biomolecule on a solid substrate, including: providing a solid substrate having a first functional group attached thereto, the first functional...
|
|
|
7611888 |
Rotaxane compound, rotaxane-bonded solid substrate, and biochip using the same
The present disclosure provides a rotaxane compound that can be used to separate molecules within a linkage layer formed on a solid substrate of a biochip by a predetermined distance. The compound...
|
|
|
7611871 |
Method for the specific determination of DNA sequences by means of parallel amplification
The invention concerns a general method for the specific determination of DNA sequences by means of parallel amplification through nested polymerase chain reaction in a combined...
|
|
|
7611870 |
Methods for identifying cancer risk
The present invention provides methods and kits for identifying an increased risk of developing cancer in a subject. The methods include analyzing a first biological sample, such as a blood sample,...
|
|
|
7611869 |
Multiplexed methylation detection methods
The present invention is directed to sensitive and accurate multiplexed assays for target analyte detection and detection of methylation in nucleic acid samples.
|
|
|
7611843 |
Eubacterial tmRNA sequences and uses thereof
The present invention is directed to eubacterial tmDNA sequences and the corresponding tmRNA sequences. The present invention is further directed to alignments of eubacterial tmDNA sequences and...
|
|
|
7611842 |
Automated seed sampler and methods of sampling, testing and bulking seeds
An automated seed sampler includes a sampling station; a sampler for removing material from a seed in the sampling station; a seed conveyer for conveying the seed from the sampling station to a...
|