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9096898 Method of determining the nucleotide sequence of oligonucleotides and DNA molecules  
The present invention relates to a novel method for analyzing nucleic acid sequences based on real-time detection of DNA polymerase-catalyzed incorporation of each of the four nucleotide bases,...
9040243 Method for detecting and/or quantifying human DNA  
The present invention relates to a method, kit and use of various nucleic acid sequences for deleting and/or quantifying one or more nucleic acids of a genome in a sample. Wherein the nucleic acid...
9040238 Polynucleotides for use in medicine  
The invention refers to polynucleotides selected from the group consisting of a) polynucleotides encoding for the polypeptide RBM20 comprising a P638L mutation for a human polypeptide RBM20, or a...
9040286 Diagnosis and treatment of cancer  
Provided herein are methods for diagnosing cancer by determining the level of expression of SETDB1 in a biological sample. Also provided herein are methods for treating cancer by administering an...
9040242 Method to amplify nucleic acids to generate fluorescence labeled fragments of conserved and arbitrary products  
Disclosed herein are methods for the identification of the species, serotype, and strain of a microorganism. Also disclosed are primers for use in detecting such microorganisms and kits comprising...
9040244 HIV-1 genotyping assay for global surveillance of HIV-1 drug resistance  
Provided herein are new methods, primers, and kits for genotyping HIV-1, including group M viral strains. The methods can be used for HIV-1 drug resistance surveillance and monitoring, for example...
9034580 Single molecule nucleic acid sequence analysis processes and compositions  
Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing nucleic acids that comprise nucleotide...
9034581 Compositions and methods for detection of Staphylococcus aureus  
The present invention relates to methods for the rapid detection of the presence or absence of Staphylococcus aureus in a biological or nonbiological sample. The present invention includes methods...
9029089 Methods for predicting survival in cancer patients  
A method for survival prediction in cancer patients is provided. In one embodiment, the survival prediction is determined by the presence or absence of KRAS gene region deletion and/or loss of...
9029091 Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line  
The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of...
9029090 Method for auxiliary identification of inbred line of wuzhishan miniature pig and its special primer  
A method for auxiliary identification of WZSP inbred line and its special primers are disclosed. The method may comprise: testing whether a deoxyribose nucleotide at site 1273 from 5′ end of...
9029103 Methods for sequencing polynucleotides  
Provided herein is a method for sequencing a polynucleotide molecules. The method includes the steps of providing a plurality of polynucleotide molecules attached to a surface, wherein a first...
9029088 Human single nucleotide polymorphisms within CODIS loci D13S317, TH01, vWA, D12S391, and D6S1043  
Disclosed are methods for human identification utilizing newly discovered single nucleotide polymorphisms (SNPs) within CODIS loci D13S317, TH01, vWA, D12S391 and D6S1043, which can cause allelic...
9029084 Polynucleotide primers  
A polynucleotide primer comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 1 to 18, 21 to 45 or 74 to 77.
9023601 Microarray synthesis and assembly of gene-length polynucleotides  
There is disclosed a process for in vitro synthesis and assembly of long, gene-length polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in situ on a microarray...
9023602 Method for detecting cyst nematodes  
The present invention relates to a method for determining the presence of a cyst nematode in a sample comprising the steps of: providing a pair of bidirectional oligonucleotide primers or an...
9024006 Mutation detection assay  
A method of sample analysis is provided. In certain embodiments, the method involves: a) amplifying a product from a sample that comprises both wild type copies of a genomic locus and mutant...
9017938 Use of microrna-199b-5p in medical and diagnostic field  
This invention concerns the use of MicroRNA-199b-5p in medical and diagnostic fields. Particularly, this invention concerns the use of the miR199b-5p in the anti-cancer therapy and as a...
9017946 Systems and methods for monitoring the amplification of DNA  
A system and method for amplifying and detecting nucleic acids are disclosed. In one embodiment, the system includes: a microfluidic device comprising a channel for receiving a sample of solution...
9017947 Soybean event MON89788 and methods for detection thereof  
The present invention provides for soybean plant and seed comprising transformation event MON89788 and DNA molecules unique to these events. The invention also provides methods for detecting the...
9017944 Methods for the prognosis of breast cancer  
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
9017971 Means and methods for investigating nucleic acid sequences  
The invention provides improved methods for investigating nucleic acid sequences, wherein at least one additional probe is used which is specific for a (pseudo)gene variant of a target nucleic acid.
9017948 Assays and other reactions involving droplets  
The present invention generally relates to droplets and/or emulsions, such as multiple emulsions. In some cases, the droplets and/or emulsions may be used in assays, and in certain embodiments,...
9012614 Rapid nucleic acid purification using paper chromatography  
Provided is a method for rapid nucleic acid purification. The method includes allowing the nucleic acid isolated from the biological sample to be adsorbed on a silica membrane; separating...
9012838 Covalently functionalized nanodiamond-based MALDI matrices and methods of use thereof  
The present disclosure relates to functionalized nanodiamonds comprising at least one MALDI matrix covalently bonded to a nanodiamond and compositions comprising the same. The present disclosure...
9012145 Protein tyrosine phosphatase mutations in cancers  
Tyrosine phosphorylation, regulated by protein tyrosine phosphatases (PTPs) and kinases (PTKs), is important in signaling pathways underlying tumorigenesis. A mutational analysis of the tyrosine...
9012149 Methods for detection and quantitation of small RNAs  
Improved methods that increase the specificity and sensitivity of detection of small RNAs, including miRNAs, using oligonucleotide primers and nucleic acid amplification, are provided. Reaction...
9005894 Determination of KIR haplotypes associated with disease  
Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes,...
9005891 Methods for depleting RNA from nucleic acid samples  
The invention relates to methods of depleting RNA from a nucleic acid sample. The RNA may be any RNA, including, but not limited to, rRNA, tRNA, and mRNA. The method is useful for depleting RNA...
9005896 Method for amplifying nucleic acids  
The present invention describes methods for amplifying a target nucleic acid wherein target nucleic acids hybridize to capture probe nucleic acids which are immobilized to a support via their 5′...
9005932 Mutational analysis  
A method for analysing genetic mutations, and in particular single nucleotide polymorphisms (SNPs) and/or somatic mutations, is described, as well as methods for preferentially amplifying one...
9005985 Optical reporter compositions  
This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to...
9005898 Method for controlling hair growth, method for selecting or evaluating hair growth control agent, and hair growth suppression agent  
The present invention provides a method for controlling hair growth, a method for selecting or evaluating a hair growth control agent, and a hair growth suppression agent. The present invention...
9005895 Compositions, methods and kits for nucleic acid synthesis and amplification  
The present invention is directed to compositions, methods and kits useful for the synthesis of nucleic acid molecules. More specifically, compositions, methods and kits are provided for the...
8999647 Methods of subclassification of ductal carcinoma in situ of the breast  
Provided herein are methods of determining the aggressiveness or indolence of a ductal carcinoma in situ lesion. Also provided are methods of developing treatment plans for subjects with a ductal...
8999643 Methods and assays for the detection of alternative lengthening of telomeres (ALT) activity in cells  
The invention relates to methods and assays for the detection of active Alternative Lengthening of Telomeres (ALT) activity in cells. The methods and assays involve detecting or assaying for...
8999634 Nucleic acid detection combining amplification with fragmentation  
Provided herein are methods and compositions for detection of a nucleic acid target in a sample. The methods and compositions use primer directed amplification in conjunction with nucleic acid...
8999646 Quality control bioassays for nutriceutical and medicinal products  
Bioassays for detecting the ability of one sample of a food substance, nutritional supplement, therapeutic agent and/or disease preventive agent relative to that of a second sample of such a...
8999648 System and method for classification of patients  
A system (100) for classifying a biological test sample, including a database (112) populated with reference expression data. The reference expression data includes expression levels of a...
8999644 Method for detecting the presence of a DNA minor contributor in a DNA mixture  
The present invention concerns a method of detecting the presence of a DNA minor contributor in a DNA mixture by determining several haplotypes present in said one or more DNA samples.
8991259 Method and system for acoustically treating material  
Methods and systems for acoustically treating material using a continuous process in which material may be caused to flow in a continuous or intermittent fashion into/out of an acoustic treatment...
8993238 Brassica GAT event and compositions and methods for the identification and/or detection thereof  
Compositions and methods related to transgenic glyphosate tolerant Brassica plants are provided. Specifically, the present invention provides Brassica plants having a DP-073496-4 event which...
8993232 Identification of the causative mutation for leopard complex spotting and congenital stationary night blindness in equines and a method for testing for same  
Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard...
8993242 Method for functional testing of site-specific DNA methylation  
Methods and kits are provided for testing the functional effect of methylating different cytosine residues, for testing patterns of DNA methylation on gene expression, and for site-specific...
8993240 Hot start reverse transcription by primer design  
The present teachings provide methods, compositions, and kits for performing primer extension reactions. In some embodiments, a reverse transcription reaction is performed on a target...
8993237 Device and method for thermal cycling  
A thermal cycling device for performing nucleic acid amplification on a plurality of biological samples positioned in a sample well tray. The thermal cycling device includes a sample block...
8993241 Reaction device, reaction method and method of synthesizing cDNA  
Provided is a device and a method whereby plural kinds of reaction operations and washing operations can be conducted in parallel without washing or replacing an instrument used in transferring a...
8993230 Asynchronous sequencing of biological polymers  
The present invention provides methods, reagents and apparatus for conducting single molecule sequencing in an asynchronous manner. The subject methods and compositions are particularly useful for...
8986934 Device for thermally regulating a rotationally symmetrical container  
The present invention relates to a device for thermally regulating a rotationally symmetrical container having a lateral surface and/or a base surface, said device comprising at least one...
8986925 Method for in vitro detection and/or quantification and/or identification of infectious compounds in a biological material  
Method for in vitro detection and/or quantification and/or identification of infectious compounds present in a fluid medium M constituting a biological material, in which method a suspension of...