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9040287 Molecular biosensors capable of signal amplification  
The present invention provides molecular biosensors capable of signal amplification, and methods of using the molecular biosensors to detect the presence of a target molecule.
9040236 Biological fluid sampling and storage apparatus for remote use  
An apparatus for sampling and storing biological fluids from a human or animal subject is provided. In one embodiment of the present disclosure, the apparatus includes a main body, lancet carrier...
9040235 Method for sequencing RNA by in-source decay using matrix assisted laser desorption ionization time of flight mass spectrometer  
An analytic method is provided for obtaining much sequence information by causing in-source decay of modified RNA and non-modified RNA and generating many fragment ions. Particularly, a method for...
9040677 Transcription activator-like effector assembly  
Described herein are techniques for assembling a polynucleotide encoding a transcription activator-like effector nucleases (TALEN). The techniques ligate and digest necessary modules for a TALEN...
9040495 General composition framework for ligand-controlled RNA regulatory systems  
The invention provides an improved design for the construction of extensible nucleic acid-based, ligand-controlled regulatory systems, and the nucleic acid regulatory systems resulting therefrom....
9040242 Method to amplify nucleic acids to generate fluorescence labeled fragments of conserved and arbitrary products  
Disclosed herein are methods for the identification of the species, serotype, and strain of a microorganism. Also disclosed are primers for use in detecting such microorganisms and kits comprising...
9040234 Oligonucleotide analogs as therapeutic agents  
The invention relates to design of short oligonucleotides and analogs thereof (such as, di-, and trinucleotide compounds) useful for various therapeutic applications. It is believed that the...
9040626 Nanofibers and morphology shifting micelles  
The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.
9040241 Genetic markers of mental illness  
This invention relates to genetic markers of mental illness, e.g., schizophrenia (SZ), and methods of use thereof.
9034576 Systems and methods for measuring translation of target proteins in cells  
The present invention relates to systems and methods for measuring the rate of translation of a target protein in cells, which are based on the detection of translation of one or more...
9034579 Nucleic acid sample preparation  
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid...
9034580 Single molecule nucleic acid sequence analysis processes and compositions  
Improved solid supports and methods for analyzing target nucleotide sequences are provided herein. Certain improvements are directed to efficiently preparing nucleic acids that comprise nucleotide...
9035150 Maize inbred PH1KHH  
A novel maize variety designated PH1KHH and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KHH with another maize plant. Methods...
9034578 Nucleic acid sample preparation  
The present invention includes methods, devices and systems for isolating a nucleic acid from a fluid comprising cells. In various aspects, the methods, devices and systems may allow for a rapid...
9035153 Maize inbred PH1KAP  
A novel maize variety designated PH1KAP and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KAP with another maize plant. Methods...
9034581 Compositions and methods for detection of Staphylococcus aureus  
The present invention relates to methods for the rapid detection of the presence or absence of Staphylococcus aureus in a biological or nonbiological sample. The present invention includes methods...
9034575 Workflow timing between modules  
The invention relates to a method of isolating and analyzing an analyte using an analytical apparatus which comprises modules of different types, wherein any one module of one type has a specific,...
9034577 Method for expression of small antiviral RNA molecules with reduced cytotoxicity within a cell  
In one aspect, the invention provides methods and compositions for the expression of small RNA molecules within a cell using a retroviral vector (FIG. 1A). Small interfering RNA (siRNA) can be...
9035149 Maize inbred PH1K8P  
A novel maize variety designated PH1K8P and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1K8P with another maize plant. Methods...
9034313 Nucleic acid molecules encoding rantes, and compositions comprising and methods of using the same  
Nucleic acid molecules comprising a nucleotide sequence encoding RANTES and fragments and variants thereof are disclosed. Additionally, nucleic acid molecules and compositions comprising the...
9029085 Assays and other reactions involving droplets  
The present invention generally relates to droplets and/or emulsions, such as multiple emulsions. In some cases, the droplets and/or emulsions may be used in assays, and in certain embodiments,...
9029128 DNA intercalator detection  
A DNA intercalator detection system can include a filtration unit and control sample conditioner operably coupled with the filtration unit and an analytic unit operably coupled with the filtration...
9029103 Methods for sequencing polynucleotides  
Provided herein is a method for sequencing a polynucleotide molecules. The method includes the steps of providing a plurality of polynucleotide molecules attached to a surface, wherein a first...
9029165 System and method for the analysis of DNA sequences in biological fluids  
A method for detecting electromagnetic waves derived from bacterial DNA, comprising extracting and purifying nucleic acids from a sample; diluting the extracted purified nucleic acids in an...
9029338 Lipid formulated compositions and methods for inhibiting expression of a gene from the ebola virus  
The invention relates to lipid formulated double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of a gene from the Ebola virus.
9029083 Vitro evolution in microfluidic systems  
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into...
9029084 Polynucleotide primers  
A polynucleotide primer comprising at least the final six nucleotides of one of the following primer sequences, or a sequence complementary thereto: SEQ. ID NOS. 1 to 18, 21 to 45 or 74 to 77.
9029096 Assay and method  
The present invention relates to a method and assay useful for determining the sensitivity of the cells of a subject to genetic damage from electromagnetic radiation. The assay may comprise a...
9023597 One step diagnosis by dendron-mediated DNA chip  
This invention relates to chips containing nucleic acid probes or primers and their use in methods to detect nucleic acid molecules. The invention includes DNA chips in contact with a thermocycler...
9023823 Micro-RNA's that regulate muscle cells  
The present invention describes microRNAs that regulate the differentiation, proliferation and death of cardiac and skeletal muscles cells. These molecules represent unique targets in the...
9024153 Maize inbred PH1KAN  
A novel maize variety designated PH1KAN and seed, plants and plant parts thereof. Methods for producing a maize plant that comprise crossing maize variety PH1KAN with another maize plant. Methods...
9023600 Highly selective pyrophosphate sensor  
A dinuclear zinc complex PPi sensor is provided, that may be represented by the formula where X is hydrogen, —COOEt, —CH═CH2, —OR, or —NR2, wherein X is a monovalent organic group having from 1 to...
9023598 Methods for diagnosing pancreatic cancer using miR-103-1, miR-103-2, miR-24-2 and miR-107  
The present invention provides novel methods and compositions for the diagnosis and treatment of solid cancers. The invention also provides methods of identifying inhibitors of tumorigenesis.
9023601 Microarray synthesis and assembly of gene-length polynucleotides  
There is disclosed a process for in vitro synthesis and assembly of long, gene-length polynucleotides based upon assembly of multiple shorter oligonucleotides synthesized in situ on a microarray...
9023650 DNA tagged microparticles  
A simulant that includes a carrier and DNA encapsulated in the carrier. Also a method of making a simulant including the steps of providing a carrier and encapsulating DNA in the carrier to...
9023599 Method of detecting the presence of pneumococcal neuraminidases in Streptococcus pneumoniae-infected samples  
A method of providing protection against pneumococcal infection in a subject is disclosed. The method includes steps of administering to the subject a composition that includes combination of...
9024118 Soybean variety XBP46005  
A novel soybean variety, designated XBP46005 is provided. Also provided are the seeds of soybean variety XBP46005, cells from soybean variety XBP46005, plants of soybean XBP46005, and plant parts...
9023825 Materials and methods related to modulation of mismatch repair and genomic stability by miR-155  
The present invention provides materials and methods related to modulation of mismatch repair and genomic stability by miR-155.
9017992 In situ hybridization detection method  
The invention provides compositions and methods for the detection of targets in a sample; in particular, an in situ hybridization (ISH) sample. Probes and detectable labels may be provided in...
9018453 Soybean variety XB49Z12  
A novel soybean variety, designated XB49Z12 is provided. Also provided are the seeds of soybean variety XB49Z12, cells from soybean variety XB49Z12, plants of soybean XB49Z12, and plant parts of...
9017954 Polymeric carriers for immunohistochemistry and in situ hybridization  
Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers...
9017617 Cassette for sample preparation  
Apparatuses for preparing a sample are disclosed herein. The apparatuses include a chamber, a first valve at least partially disposed in the first chamber, a second valve at least partially...
9017938 Use of microrna-199b-5p in medical and diagnostic field  
This invention concerns the use of MicroRNA-199b-5p in medical and diagnostic fields. Particularly, this invention concerns the use of the miR199b-5p in the anti-cancer therapy and as a...
9017946 Systems and methods for monitoring the amplification of DNA  
A system and method for amplifying and detecting nucleic acids are disclosed. In one embodiment, the system includes: a microfluidic device comprising a channel for receiving a sample of solution...
9018184 Inhibitors of SP140 and their use in therapy  
A method of treating autoimmune and inflammatory diseases or conditions in a mammal, such as a human, which comprises the administration of a inhibitor of bromodomain-containing protein: SP140.
9017937 Nanopore sequencing using ratiometric impedance  
The invention relates to devices and methods for nanopore sequencing. The invention includes arrays of nanopores having incorporated electronic circuits, for example, in CMOS. The invention...
9017944 Methods for the prognosis of breast cancer  
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for...
9017972 DNA methylation analysis of regulatory T cells through DNA-methylation analysis of the TSDR region of the gene FOXP3  
The present invention relates to a method, in particular an in vitro method for identifying FoxP3-positive CD25+CD4+ regulatory T cells of a mammal, comprising analyzing the methylation status of...
9017970 RNA polyphosphatase compositions, kits, and uses thereof  
The present invention relates to the discovery of RNA 5′ polyphosphatase enzymes not previously described in the art, methods for discovery of said enzymes, compositions of said enzymes, methods...
9017945 Method for sequencing a polynucleotide template  
The invention relates to methods for pairwise sequencing of a double-stranded polynucleotide template, which permit the sequential determination of nucleotide sequences in two distinct and...