|
Match
|
Document |
Document Title |
|
|
7575868 |
Methods for assessing efficacy of chemotherapeutic agents
Methods are provided for accurately predicting efficacy of chemotherapeutic agents. Methods of the invention increase the positive predictive value of chemosensitivity assays by assessing both the...
|
|
|
7575864 |
Method for the direct detection of diagnostic RNA
Methods for the direct detection of diagnostic target RNA have been developed, which obviate the need for time consuming RNA purification and isolation procedures.
|
|
|
7575861 |
Compositions and method for accurate early pregnancy diagnosis
The invention provides improved assays for detection of pregnancy. In the assays, pregnancy associated glycoproteins are analyzed in conjunction with progesterone analysis. The techniques of the...
|
|
|
7576192 |
Rapid and sensitive assay for the detection and quantification of coregulators of nucleic acid binding factors
Biosensors and methods to determine the activity of any and all nucleic acid binding factors, proteins, cellular events, nucleic acid binding protein coregulators, or fragments thereof, based upon...
|
|
|
7575869 |
Genome wide location and function of DNA binding proteins
The present invention relates to a method of identifying a region (one or more) of a genome of a cell to which a protein of interest binds. In the methods described herein, DNA binding protein of a...
|
|
|
7575918 |
Tissue-specific and pathogen-specific ribozymes
The present invention relates to the discovery, identification and characterization of toxic agents which are lethal to pathogens and methods for targeting such toxic agents to a pathogen or...
|
|
|
7572585 |
Enzymatic labeling of RNA
Methods are described in which a sample containing RNA is contacted with an enzyme having an RNA ligation activity in the presence of a labeled substrate to provide labeled RNA. Methods of...
|
|
|
7572616 |
Alternative oxidase and uses thereof
The invention relates to a method for combating disorders affecting the mitochondrial oxidative phosphorylation system by allotopic expression of the cyanide-insensitive alternative oxidase (AOX)...
|
|
|
7572577 |
Methods for recovery of DNA from mRNA in ribosome display complexes
The invention provides a method for recovery of cDNA from mRNA, comprising reverse transcription (RT) of mRNA using a RT primer which includes a sequence based on the 5′ consensus region of the...
|
|
|
7572887 |
Gene expressed in prostate cancer, methods and use thereof
A polypeptide is disclosed that is specifically detected in the cells of the prostate, termed Splice Variant-Novel Gene Expressed in Prostate (SV-NGEP). Polynucleotides encoding SV-NGEP are also...
|
|
|
7572584 |
Species-specific primer sets and identification of species-specific DNA sequences using genome fragment enrichment
Targeted sequencing of genetic regions that differ between two DNA preparations uses genomic fragment enrichment. This method can be used to study genetic variation among closely related species...
|
|
|
7572582 |
Oligonucleotide analogues
The present invention relates to novel bicyclic and tricyclic nucleoside and nucleotide analogues as well as to oligonucleotides comprising such elements. The nucleotide analogues, LNAs (Locked...
|
|
|
7572578 |
Method for isolating and purifying a nucleic acid
The present invention is a method for isolating and purifying a nucleic acid, where generation of foams is able to be suppressed whereby the isolation and purification of a nucleic acid are easily...
|
|
|
7572434 |
Method for assessing the effect of a drug on long term memory formation
Methods of assessing the effect of a drug on long term memory and for screening a pharmaceutical agent for its ability to modulate long term memory are disclosed.
|
|
|
7572828 |
Identification of anti-HIV compounds inhibiting virus assembly and binding of nucleocapsid protein to nucleic acid
The invention provides methods and pharmaceutical compositions for inhibiting viral replication, particularly retroviral replication. The methods comprise administration of stibonic acid or...
|
|
|
7572588 |
Modified probe molecules having self-complementary regions
The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a...
|
|
|
7572586 |
Identifying susceptibility to cardiac hypertrophy
This document provides methods and materials related to identifying, assessing, and predicting hypertrophic cardiomyopathy (HCM) in mammals. For example, methods and materials for using mutations...
|
|
|
7572587 |
Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and Ctenocephalides spp
Disclosed is a novel δ-endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea ( Ctenocephalides felis ), as well as...
|
|
|
7572643 |
Nanoparticle composite-coated glass microspheres for use in bioassays
A microsphere for use in a bioassay comprising a glass core coated with a nanoparticle composite comprising a bioactive probe is provided. The nanoparticle composite coating enhances the density of...
|
|
|
7572579 |
Screening method for a ribonuclease H inhibitor of a reverse transcriptase
A screening method for a compound which inhibits a ribonuclease H activity of a reverse transcriptase which includes incubating a substrate with an appropriate primer hybridized to an appropriate...
|
|
|
7572580 |
Promoter variants of the alpha-7 nicotinic acetylcholine receptor
The present invention is directed to methods and compositions related to α7 acetylcholine nicotinic receptor genes, in particular, the human α7 nicotinic acetylcholine receptor gene. The human...
|
|
|
7572576 |
Method of predicting genetic risk for hypertension
It is intended to provide a means of predicting genetic risk for hypertension at a high accuracy and high prediction possibility. Namely, risk for hypertension is predicted by a method involving...
|
|
|
7572409 |
Ionic liquid apparatus and method for biological samples
Apparatus and method for handling biological samples. Segments of ionic liquid can provide voltage across segments of immiscible liquid to concentrate or separate charged species in the biological...
|
|
|
7569397 |
Immunoassay devices and use thereof
An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site...
|
|
|
7569381 |
Biochemical reaction cassette with improved liquid filling performance
A biochemical reaction cassette comprises a housing member, a reaction chamber arranged in the housing member and having a bottom section and a ceiling facing the bottom section, an injection port...
|
|
|
7571055 |
Systemic lupus erythematosus
This document relates to methods and materials involved in diagnosing SLE. For example, this document relates to methods and materials involved in diagnosing SLE, diagnosing severe SLE, and...
|
|
|
7569345 |
Gene expression markers for breast cancer prognosis
The present invention provides gene sets the expression of which is important in the diagnosis and/or prognosis of breast cancer.
|
|
|
7569350 |
Methods for selecting cancer vaccine therapies using extracellular DNA
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
|
|
|
7569341 |
Nucleic acid directed immobilization arrays and methods of assembly
The invention relates to supramolecular bioconjugates and to methods for assembling and utilizing supramolecular bioconjugates. Supramolecular bioconjugates comprise a plurality of first nucleic...
|
|
|
7569366 |
PCR amplification reaction apparatus and method for PCR amplification reaction using apparatus
The present invention provides a method for PCR amplification reaction that can reduce the time required for amplification reaction of nucleic acid by PCR using the target nucleotide molecule as a...
|
|
|
7569349 |
Methods for selecting monoclonal antibody therapies using extracellular DNA
This invention relates to detection of specific extracellular nucleic acid in plasma or serum fractions of human or animal blood associated with neoplastic or proliferative disease. Specifically,...
|
|
|
7569812 |
Remote reagent ion generator
An improved ion source and means for collecting and focusing dispersed gas-phase ions from a remote reagent chemical ionization source (R2CIS) at atmospheric or intermediate pressure is described....
|
|
|
7569375 |
Alcohol dehydrogenases with increased solvent and temperature stability
The invention relates to biocatalysts showing alcohol dehydrogenase activity obtainable from Rhodococcus ruber , their preparation, their use in the oxidation of secondary alcohols and/or the...
|
|
|
7569367 |
Nucleic acid preparation from whole blood for use in diagnosis of transmissible spongiform encephalopathy
The present invention deals with a method of preparing nucleic acids, particularly RNA, from a whole blood sample. The nucleic acids purified by the method of the invention are particularly suited...
|
|
|
7569342 |
Removal of molecular assay interferences
Methods and systems for removing masking agents from test samples, e.g., DNA-containing samples obtained from living subjects, when they are submitted for or subjected to molecular assays. The...
|
|
|
7569346 |
Method for separating analyte from a sample
An analyte is separated from a fluid sample by introducing the sample into a cartridge having a sample port and a first flow path extending from the sample port. The first flow path includes an...
|
|
|
7569344 |
Detection of human papilloma virus in papanicolaou (Pap) smears
Methods and reagents for detecting high-risk human papilloma virus (HPV) DNA types in cells on a Pap smear that indicates the patient is at higher risk for cancer are described. The method uses...
|
|
|
7569390 |
Selection of intracellular immunoglobulins
A general immunoglobulin-target assay system is provided, in which a positive outcome (the generation of a signal) depends only on the intracellular interaction of immunoglobulin with target. This...
|
|
|
7569347 |
Apparatus, methods and compositions for biotechnical separations
RNA, preferably messenger RNA, is purified by use of selective precipitation, preferably by addition of compaction agents. Also included is a scalable method for the liquid-phase separation of DNA...
|
|
|
7569348 |
Method and apparatus for pattern identification in diploid DNA sequence data
This invention provides methods for identifying mutations and methylation patterns in diploid DNA sequence signal data. In particular, the invention provides methods for (1) obtaining two parental...
|
|
|
7569681 |
Caterpiller gene family
The present invention relates to a new family of structurally and functionally related nucleic acids and proteins, designed the CATERPILLER family, which is characterized by landmark structural...
|
|
|
7569388 |
Plants having an enhanced amino acid content, plants having an enhanced nitrogen content, plants tolerant to nitrogen deficiency, and methods for producing them
The object of the present invention is to provide a transformed plant having an enhanced amino acid content, a progeny of the plant, seeds of the plant and a method for producing the plant. The...
|
|
|
7569355 |
Homogeneous luminescence energy transfer bioassay
A homogeneous bioassay including a first group labelled with an energy donor and a second group labelled with an energy acceptor, where the donor is a luminescent lanthanide label capable of...
|
|
|
7569343 |
Methods to assess quality of microarrays
The present invention relates to methods and compositions for assessing the quality of microarrays. In particular, the invention relates to the use of quality control probes that are synthesized on...
|
|
|
7566700 |
Materials and methods for treatment of allergic disease
siRNA molecules are disclosed which target the transcription factor STAT6 and repress the expression of STAT6 mRNA, STAT6 protein and STAT6 function in lung cells. The use of STAT6 specific siRNA...
|
|
|
7566538 |
Sequencing by incorporation
Nucleotides and nucleotide analogs are used in various sequencing by incorporation/sequencing by synthesis methods. Nucleotide analogs comprising 3′-blocking groups are used to provide reversible...
|
|
|
7567870 |
Multiparameter analysis for predictive medicine
The invention provides a method of determining a comparative expression profile in an individual by comparing the expression levels of a sample of molecules in a population of molecules in a...
|
|
|
7566701 |
Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics
The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnostics of thrombotic...
|
|
|
7566536 |
WNT-regulated cytokine-like polypeptide and nucleic acids encoding same
The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a...
|
|
|
7566775 |
N8- and C8-linked purine bases and structurally related heterocycles as universal nucleosides used for oligonucleotides hybridization
The present invention is directed to a nucleic acid binding compound comprising N 8 - or C 8 -linked purine bases or structurally related heterocycles, a compound useful for the preparation of such...
|