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7601520 |
Method for rapid identification of porcine insulin-like growth factor 2 intron 7 point mutation
A method for rapidly identifying a point mutation in porcine insulin-like-growth factor 2 intron 7 uses published primers to amplify the target DNA fragments by polymerase chain reaction. The DNA...
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7601494 |
Method of screening candidate compounds for susceptibility to biliary excretion
A method of screening a candidate compound for susceptibility to biliary excretion by a hepatocyte transport protein. The method includes the steps of providing a culture of hepatocytes comprising...
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7601821 |
Encoding and decoding reactions for determining target molecules
The present invention is directed to methods, reagents, and kits for detecting the presence or absence of (or quantifying) target polynucleotide sequences and proteins in at least one sample using...
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7601496 |
Cleavage of nucleic acids
The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5′ nucleases and 3′ exonucleases, are used to detect and...
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7601498 |
Methods of using dyes in association with nucleic acid staining or detection and associated technology
Methods of using dyes and associated technology are provided. A dye, such as a monomeric dye or a dimeric dye, may be used in a nucleic acid gel staining application and/or a nucleic acid detection...
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7601807 |
Protease, DNA encoding the same, and method for manufacturing protease
A protease having the following characteristics:
(i) a molecular weight of 21,000±1,000 (by SDS-PAGE) and (ii) specific protease activity cutting the Gly-Phe site of a peptide or protein...
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7601700 |
Modulation of eIF4E expression
Oligomeric compounds, compositions and methods are provided for modulating the expression of eIF4E. The antisense compounds may be single- or double-stranded and are targeted to nucleic acid...
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7601828 |
Estimation method, human estrogen receptor alpha gene, genomic DNA, and diagnostic marker
Evaluation methods for evaluating susceptibility to multifactorial diseases in sexual differentiation disorders, human estrogen receptor alpha (α) genes carrying single nucleotide polymorphisms...
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7601885 |
Transgenic plant comprising a cassava vein mosaic virus promoter and a heterologous nucleic acid sequence
The invention relates to compositions and methods useful for the production of transgenic plants. In particular, the invention relates to cassava vein mosaic virus (CsVMV) promoter sequences and...
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7601493 |
Methods and apparatus for screening and detecting multiple genetic mutations
An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a...
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7601495 |
Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
The present invention is directed to methods, reagents, kits, and compositions for identifying and quantifying target polynucleotide sequences. A linker probe comprising a 3′ target specific...
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7601822 |
Molecular identification of bacteria of genus Streptococcus and related genera
The invention concerns a method for detecting by molecular identification a bacterium of one of the species of genus Streptococcus and four related genera Enterococcus, Gemella, Abiotrophia and...
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7601851 |
Compounds and methods for fluorescent labeling
Dye reagents useful in labeling biological materials are provided along with methods for their use.
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7601502 |
Prime boost vaccine for the protection of equines against equine influenza
The present invention is concerned with vaccinating equines against the equine influenza virus (EIV). It has now been found that adequate protection against equine influenza in equines can be...
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7601497 |
Detection of nucleic acids by target-specific hybrid capture method
Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous...
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7601492 |
Genome mapping of functional DNA elements and cellular proteins
The disclosure provides methods of examining the binding of proteins to DNA across a genome (e.g., the entire genome or a portion thereof, such as one or more chromosomes or a chromosome regions)....
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7598093 |
Nanoparticle and microparticle based detection of cellular products
Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic...
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7597932 |
Mesoporous permeation layers for use on active electronic matrix devices
The present invention provides improved synthetic polymer hydrogel permeation layers for use on active electronic matrix devices for biological assays. The present invention includes methods for...
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7598032 |
Thermostable DNA polymerases incorporating nucleoside triphosphates labeled with fluorescent dyes
Modified thermostable DNA polymerases having enhanced efficiency for incorporating unconventional nucleotides such as those labeled with fluorescein family dyes are advantageous in many in vitro...
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7598361 |
Nucleic acid molecules and other molecules associated with the sucrose pathway
The present invention is in the field of plant biochemistry. More specifically the invention relates to nucleic acid sequences from plant cells, in particular, nucleic acid sequences from maize and...
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7598061 |
Mold infections
Methods are disclosed for detecting, quantifying and/or identifying a fungal species in a sample or for diagnosing jejunal hemorrhage syndrome in a subject. The methods generally include amplifying...
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7598034 |
Method of identifying hairpin DNA probes by partial fold analysis
Method of identifying molecular beacons in which a secondary structure prediction algorithm is employed to identify oligonucleotide sequences within a target gene having the requisite hairpin...
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RE40929 |
Chromosome-specific staining to detect genetic rearrangements associated with chromosome 3 and/or chromosome 17
Methods and compositions for staining based upon nucleic acid sequence that employ nudeic nucleic acid probes are provided. Said methods produce staining patterns that can be tailored for...
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7598031 |
Method for the detection of gene transcripts in blood and uses thereof
The present invention is directed to detection and measurement of gene transcripts in blood. Specifically provided is a RT-PCR analysis performed on a drop of blood for detecting, diagnosing and...
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7598369 |
siRNA targeting histamine receptor H1
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7598037 |
Method for implementing non-destructive quality control of substrates and printed biological microarrays
A method and apparatus are provided for implementing non-destructive quality control of substrates and printed biological microarrays. A method and apparatus are provided for implementing quality...
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7598039 |
Treatment of insulin resistance
Disclosed are a method of for treating insulin resistance and a method identifying a compound for treating insulin resistance.
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7598370 |
siRNA targeting polo-like kinase-1 (PLK-1)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7599800 |
Apparatus and method for coding genetic information
Provided are an apparatus and a method for coding genetic information. An aligning unit aligns sample genetic information, wild-type probe genetic information, and mutant-type probe genetic...
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7598080 |
Diagnostic assay for source of inflammation
A method of diagnosing the source of local, acute inflammation has been developed based on the discovery that white cells have different patterns of gene expression, and therefore protein markers,...
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7598060 |
Rapid analysis of variations in a genome
The invention provides a method useful for determining the sequence of large numbers of loci of interest on a single or multiple chromosomes. The method utilizes an oligonucleotide primer that...
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7599799 |
Methods for using co-regulated genesets to enhance detection and classification of gene expression patterns
The present invention provides methods for enhanced detection of biological response patterns. In one embodiment of the invention, genes are grouped into basis genesets according to the...
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7598036 |
Apparatus and methods for efficient processing of biological samples on slides
Microscope slides which are useful for manually or automatically processing biological samples are described. External controls may be placed directly on the microscope slide in conjunction with a...
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7598035 |
Method and compositions for ordering restriction fragments
The invention provides a method for constructing a high resolution physical map of a polynucleotide. In accordance with the invention, nucleotide sequences are determined at the ends of restriction...
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7598052 |
Expression profile of thyroid cancer
The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides gene expression...
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7598040 |
Compositions and methods for the identification of inhibitors of protein synthesis
Compositions and methods for identifying inhibitors of RNA-target molecule interactions are provided as well as identifying inhibitors that block the role of tRNA in protein synthesis. The methods...
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7598033 |
Method and devices for running reactions on a target plate for MALDI mass spectrometry
A peptide or protein microassay method and apparatus in which a wide variety of chromogenic or fluorogenic peptide or protein substrates of interest are individually suspended or dissolved in a...
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7598038 |
Method for estimating end use qualities of wheat at growth stage
The invention provides a means for estimating the end use qualities of wheat flour that will be obtained in the future from the harvested wheat at an early stage before maturation of the wheat...
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7598063 |
Process for producing ethanol by using recombinant coryneform bacterium
The present invention provides a process for highly efficiently producing ethanol at a high productivity consisting of using a coryneform bacterium which has been transformed by a DNA containing a...
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7595883 |
Biological analysis arrangement and approach therefor
Characteristics of a chemical or biological sample are detected using an approach involving light detection. According to an example embodiment of the present invention, an assaying arrangement...
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7595164 |
Compositions and methods to detect Candida albicans nucleic acid
Compositions are disclosed as nucleic acid sequences that may be used as amplification oligomers, including primers, capture probes for sample preparation, and detection probes specific for ...
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7595385 |
Polymorphisms in the region of the human hemochromatosis gene
Polymorphic sites in the region surrounding the HH gene are provided. These polymorphisms are useful as surrogate markers in diagnostic assays for hemochromatosis.
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7595279 |
Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
A polyelectrolyte having multiple exposed functional groups, each such group being capable of covalently bonding to a molecule, is immobilized on a surface for the purpose of bonding to a...
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7595179 |
Recombinant reverse transcriptases
The present invention relates to a gene that encodes a hyperactive reverse transcriptase having DNA polymerase activity and substantially reduced RNase H activity, vectors containing the gene and...
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7595155 |
Multiplex detection probes
The present invention comprises detection probes utilizing vesicles or soluble bodies to retain multiple mass tag molecules. The detection probes may be used to simultaneously assay a plurality of...
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7595158 |
Bcl2L12 polypeptide activators and inhibitors
The invention provides methods and materials related to Bcl2L12 polypeptides and the biological activities of Bcl2L12 polypeptides. For example, the invention provides methods and materials related...
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7595160 |
Analyte detection using barcoded polymers
The invention relates to methods and systems for identifying, quantitating and/or analyzing analytes from samples. The analytes may be organic or inorganic in nature and include but are not limited...
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7595148 |
Methods and compositions for modulating T lymphocytes
This invention provides novel methods and compositions for modulating T cell differentiation and T cell responses. The modulators are identified by screening test compounds for ability to modulate...
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7595388 |
siRNA targeting EPH receptor A3 (EPHA3)
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene...
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7595159 |
Prediction of Parkinson's disease using gene expression levels of peripheral blood samples
The present invention identifies a number of gene markers whose expression is altered in neurodegenerative diseases (ND). These markers can be used to diagnose or predict ND in subjects, and can be...
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