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8148556 |
Method of producing tibolone metabolites by fermentation with Rhizopus stolonifer
A new method of producing metabolites of tibolone comprising fermenting tibolone with Rhizopus stolonifer (ATCC 12938) resulting in the formation of Δ4-Tibolone (C21H28O2), 6β-Hydroxytibolone, a...
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8008040 |
Process for production of 5-ene-3-one or 3,6-dione derivatives of sterols, processes for production of lipid metabolism improvers, foods, drinks, and animal feeds, and analytical method
An object of the present invention is to provide a process according to which 5-ene-3-one or 3,6-dione derivatives of sterols can be synthesized with a better yield, as well as a process for...
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7977065 |
Yeast strains autonomously producing steroids
The present invention relates to genetically modified yeast strains autonomously producing, from a simple carbon source, steroids. The invention also relates to a method for producing steroids from...
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7932057 |
Method for preparing 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (ginsenoside M1) by using sanqi leaves and stems
The present invention provides a method for preparing 20-O-β-D-glucopyranosyl-20(S)-protopanaxadiol (Ginsenoside M1) by using Sanqis leaves and stems. The method of the invention includes the ...
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7901904 |
Method and intermediates for preparing 2-alkoxy and 2-aryloxy estrogen compounds
The present invention relates to a method for preparing 2-alkoxy and 2-aryloxyestrogen compounds, and the intermediate compounds prepared during the use of this method, which intermediate compounds...
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7838264 |
Method for producing antcin K, zhankuic acid A, zhankuic acid B or zhankuic acid C from the mycelium of Antrodia cinnamomea
The present invention provides a method for producing antcin K, zhankuic acid A, zhankuic acid B or zhankuic acid C from the mycelium of the fungus Antrodia cinnamomea by culturing the fungus on a...
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7759101 |
Ginsenoside glycosidases hydrolyzing ginsenoside sugar moieties and uses thereof
The invention relates to ginsenoside glycosidases which hydrolyzes ginsenosides having higher contents in ginsengs so as to prepare rare ginsenosides with high physioloigical activity. Said...
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7670829 |
Yeast strains autonomously producing steroids
The present invention relates to genetically modified yeast strains autonomously producing, from a simple carbon source, steroids. The invention also relates to a method for producing steroids from...
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7608421 |
Method for the production of 7-dehydrocholesterol and/or the biosynthetic intermediate or subsequent products thereof in transgenic organisms
The present invention relates to a method for preparing 7-dehydrocholesterol and/or the biosynthetic intermediates and/or secondary products thereof by culturing organisms, in particular yeasts....
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RE40835 |
Enhancement of immunochemical staining in aldehyde-fixed tissue
A method for restoring immunoreactivity of a tissue, particularly decalcified tissue, fixed width an aldehyde fixative agent and embedded in an embedding medium, usually comprising celloidin, the...
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7556937 |
Method for producing ergosta-5,7-dienol and/or biosynthetic intermediate and/or secondary products thereof in transgenic organisms
The present invention relates to a method for the production of ergosta-5,7-dienol and/or its biosynthetic intermediates and/or metabolites by culturing genetically modified organisms, and to the...
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7432075 |
Indentification of 3-ketosteroid 9-alfa-hydroxylase genes and microorganisms blocked in 3-ketosteroid 9-alfa-hydroxylase activity
The invention relates to an isolated polynucleotide sequence comprising a nucleic acid sequence encoding the amino acid sequence of KshA protein or of KshB protein, encoded by nucleotides 499-1695...
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7300771 |
Process to produce 19-nor-10β-carboxylic acids by fungal oxidation of 6-substituted-Δ6-pregnanes
A process to produce 19-nor-10β-carboxylic acids by fungal oxidation of 6-substituted-Δ6-pregnanes is disclosed.
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7270789 |
Pipettor head having standpipes open at their tops to a pressure/vacuum chamber and method
In a preferred embodiment, a pipettor head, including: a body; one or more solenoid valves disposed in the body; each one or more solenoid valves having an outlet at a lower end and an inlet at an...
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7259005 |
Microorganism having ability to convert sterol into androst-4-ene-3, 17-dione/androsta-1,4-diene-3, 17-dione and preparation method and use thereof
Disclosed is a microorganism having an excellent ability to convert sterol into and rost-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD), a method for preparation of the microorganism...
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7241589 |
Method for preparation of androst-4-ene-3,17-dione and androsta-1,4-diene-3,17-dione
The present invention relates to a method for preparation of androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD). More particularly, the present invention relates to a method for...
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7087402 |
Selective transesterification of stanols in mixtures comprising sterols and stanols
The present invention is related to a process for selectively transesterifying stanols in mixtures comprising sterols and stanols, and a process for separating sterols from said mixtures. The...
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7078544 |
Process for producing sterol or stanol esters by enzymatic transesterification in solvent and water free media
A process for producing steryl or stanyl esters, comprises the steps of: a) forming a reacting mixture by contacting a lipase with a reactant mixture wherein the reactant mixture comprise sterols...
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7022508 |
Saponin-digesting enzymes, genes thereof and soyasapogenol B mass production system
The present invention provides a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce...
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6878535 |
Process for producing soyasapogenol B and novel microorganisms
An objective of the present invention is to provide a method of producing soyasapogenol B and to provide novel microorganisms. The present invention provides a method of producing soyasapogenol B...
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6828120 |
Process to prepare 11β, 17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dione 21-acetate
The present invention is a novel process for the transformation of 17α-hydroxy-6α-methylpregn-4-ene-3,20-dione 17-acetate (I) to 11β,17α,21-trihydroxy-6α-methylpregna-1,4-diene-3,20-dion
e 21-a...
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6660725 |
Method and composition for modulating amyloidosis
Methods for modulating amyloid deposition in a subject are described. An effective amount of at least one ATP binding cassette (ABC) transporter blocker is administered to a subject, such that...
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6586201 |
Method of chromatographic isolation for non-glyceride components
A method of chromatographic isolation for non-glyceride components (squalenes, carotenes, vitamin E, sterols and/or the like) from a non-glyceride components-comprising compound by the steps of a....
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6528280 |
Process for the preparation of derivatives of ruscus aculeatus steroid glycosides
A process for the preparation of desglucodesrhamnoruscin which comprises the hydrolysis of Ruscus Aculeatus steroid glycosides (ruscosaponins) through fermentation of a substrate containing said...
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6521600 |
Compound, WF002, production thereof and use thereof
The present invention provides a new bioactive compound of formula (I), which has an antimicrobial activity against pathogenic microorganisms, and a process for production thereof. Also provided...
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6503749 |
Yeast strains possessing the interrupted ATF2 gene and their applications
A subject of the invention is a modified yeast strain in which the acetyl-CoA pregnenolone acetyltransferase (APAT) activity is eliminated by altering the gene coding for this activity with...
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6410759 |
Dihydroxycholesterol hydroxylated at 17- and 25-positions
A method for preparing at least one hydroxycholesterol chosen from the group consisting of 25-hydroxycholesterol, 17,25-dihydroxycholesterol and 25,26-dihydroxycholesterol by biological...
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6312919 |
Process for producing a cholesterol-reduced substance
An enzymatic process is presented for reducing the cholesterol level of foods and feeds by converting the cholesterol therein to coprostanol which has a very low intestinal tract absorbability....
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6297043 |
Mumbaistatin, a process for it's production and its use as a pharmaceutical
The present invention relates to a compound named Mumbaistatin, its pharmaceutically acceptable salts and derivatives, a process for its production, and its use as a pharmaceutical. Mumbaistatin is...
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6146844 |
Process for producing hydroxylated cholesterols and dihydroxycholesterols using amycolata
A method for preparing at least one hydroxycholesterol chosen from the group consisting of 25-hydroxycholesterol, 17,25-dihydroxycholesterol and 25,26-dihydroxycholesterol by biological...
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6071714 |
Process for the microbial conversion of phytosterols to androstenedione and androstadienedione
A novel process for the fermentation of phytosterol compositions to androstenedione (androst-4-ene-3,17-dione, AD) and/or androstadienedione (androsta-1,4-diene-3,17-dione, ADD) is disclosed. The...
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5989881 |
Nucleic acid molecules encoding delta-5,7-sterol, delta-7 reductase from arabidopsis thaliana
A nucleic acid sequence containing a sequence coding for a protein having a delta-5,7 sterol, delta-7 reductase activity, said nucleic acid being a DNA or an RNA, production process, strains of...
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5989855 |
Bile acid converting microorganism and process for preparing bile acid
A microorganism having a capability of introducing a 7β-hydroxyl group into a 7-unsubstituted bile acid, and a process for preparing a bile acid having a 7β-hydroxyl group characterized by b...
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5919673 |
One-pot enzymatic sulfation process using 3'-phosphoadenosine-5'-phosphosulfate and recycled phosphorylated adenosine intermediates
A process for the enzymatic synthase of sulfate esters is disclosed in which intermediate phosphorylated adenosine compounds are recycled to minimize enzyme inhibition. Exemplary enzymes include...
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5888821 |
Cholesterol derivative for liposomal gene transfer
The invention relates to a new cholesterol derivative for liposomal gene transfer. Areas of application of the invention are medicine and genetic engineering.The new cholesterol derivative,...
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5876993 |
Epicholesterol dehydrogenase
The present invention relates to a process for producing a cholesterol-reduced substance obtained by converting cholesterol in a substance to epicholesterol, as well as to a novel cholesterol...
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5853663 |
Pressure distributor and multi-macrocarrier assembly for ballistic transfer transfection apparatus
The ballistic transfer transfection technology employs a cold gas shock wave to accelerate microprojectiles that carry matter into cells by mechanical force. The present invention relates to a...
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5849540 |
Thiodepsipeptide isolated from a marine actinomycete
The present invention is directed to a novel depsipeptide has been isolated from a new marine strain L-13-ACM2-092 belonging to the family Micromonosporaceae. Its production by aerobic fermentation...
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5830757 |
Stimulation of Meiosis
The present invention relates to the use of certain chemical compounds which interfere with the biosynthesis of cholesterol and medicaments comprising such compounds for stimulating the meiosis of...
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5792657 |
Steroid secreting human adrenocortical carcinoma cell lines
Continuous cell lines have been established from adrenocortical corcinomas. The cell lines are maintained in fully defined serum-free, steroid-free mediums. The cells of the invention, as...
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5759801 |
Δ5,7 -sterol reductase from arabidopsis thaliana
A nucleic acid sequence containing a sequence coding for a protein having a delta-5,7 sterol, delta-7 reductase activity, said nucleic acid being a DNA or an RNA, production process, strains of...
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5716800 |
Anti-acne composition containing a Poria cocos wolf extract
The invention concerns the use of an organic or hydro-organic extract of Poria cocos Wolf fungi for the preparation of a cosmetic and/or pharmaceutical composition, in particular a dermatological...
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5712109 |
Antifungal agent produced by arthrinium arundinis ATCC 74359
There is disclosed a compound having the formula ##STR1## which is produced by the fungus, Arthrinium arundinis ATCC 74359, and exhibits antifungal activity.
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5627057 |
Inhibitor compounds of farnesyl-protein transferase and chemotherapeutic compositions containing the same, produced by strain ATCC 55532
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FPTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to...
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5605634 |
Treatment of contaminated groundwater
The system places traces of nutrients and other treatment substances in the ground, in the path of an on-coming plume of contaminated groundwater. Boreholes placed across the plume contain...
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5582828 |
Active fractions of Cordyceps sinensis and method of isolation thereof
A method for identifying and isolating the active fractions in Cordyceps sinensis. It covers a findings of the structure of an active compound that is present in the active fraction, an isolation...
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5523214 |
Method of visually demonstrating the presence of microorganisms, identifying them, and testing them for sensitivity to antibiotics with redox indicators
A method of visually demonstrating the growth of such microorganisms as fungi, yeasts, and bacteria, especially mycobacteria, identifying them, and testing them for sensitivity to antibiotics by...
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5503988 |
Process for producing a cholesterol-reduced substance
The present invention relates to a process for producing a cholesterol-reduced substance obtained by converting cholesterol in a substance to epicholesterol, as well as to a novel cholesterol...
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5480781 |
Bacillus strains for oxidizing hydroxy groups of cholic acid and cheno deoxycholic acid to keto groups
Microorganisms from the genus Bacillus are used to convert chenodeoxycholic acid to 3-alpha-hydroxy-7-keto-5-beta-cholanic acid under aerobic conditions and alkaline pH. Preferred strains are...
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5480805 |
Composition for modulating sterols in yeast
A structural gene encoding a polypeptide with Δ8-7 sterol isomerase activity is disclosed, Recombinant DNA molecules useful for transforming yeast and mutant yeast transformed with such ...
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