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8445192 |
Device and method for detection and identification of immunological proteins, pathogenic and microbial agents and cells
The present invention provides a method and device for detecting and quantifying the concentration of magnetic-responsive micro-beads dispersed in a liquid sample. Also provided is a method and...
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8444986 |
Monoclonal antibodies specific to hemagglutinin from influenza virus H5-subtype and uses thereof
Monoclonal antibodies and related binding proteins that are specific for conformational epitopes of avian influenza virus K5 subtype hemagglutinin glycoprotein are provided. The antibodies can be...
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8445293 |
Method to increase specificity and/or accuracy of lateral flow immunoassays
The present invention includes methods and devices for preventing interfering substances from affecting the accuracy of a lateral flow immunoassay. In preferred embodiments, a test strip includes a...
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8445191 |
Polymeric carriers for immunohistochemistry and in situ hybridization
Certain disclosed embodiments of the present invention concern the synthesis, derivatization, conjugation to immunoglobulins and signal amplification based on discrete, relatively short polymers...
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8440447 |
Extraction and concentration method
A method for extraction and concentration of antibodies, antigens, bacteria and virus from biological samples. The method also provides a preparation that is suitable for use as a vaccine. The...
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8435731 |
Markers for viral infections and other inflammatory responses
Compositions and methods for the detection, diagnosis and treatment of BVDV are provided.
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8435732 |
Chimeric construct of mungbean yellow mosaic india virus (MYMIV) and its uses thereof
A recombinant DNA construct, recombinant vectors and host cells comprising the dimers of DNA A and DNA B of Mungbean Yellow Mosaic India Virus (MYMIV) in a single Ti plasmid are provided herein.
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8426574 |
Identification of astrovirus VA1 associated with gastroenteritis in humans
Provided herein is a novel human astrovirus, its nucleic acid sequence, as well as methods to detect and diagnose the presence of the astrovirus.
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8426125 |
Method of pretreating specimen and immunoassay using the same
The present invention provides a method of pretreating a specimen, which allows measurement according to an immunoassay to be carried out on a specimen from nasal secretion while preventing...
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8425898 |
Compositions, methods, and kits for eliciting an immune response
The present invention relates to compositions, methods, and kits for eliciting an immune response to at least one CMV antigen expressed by a cancer cell, in particular for treating and preventing...
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8426124 |
Two-step temperature profile for the propagation of viruses
The present invention provides a method for the production of a virus. The method includes providing a host cell that has been infected by the virus and cultivating the infected host cell at two...
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8420373 |
Permissive cells and uses thereof
The invention relates generally to the field of virology. More particularly, the present invention relates to methods for determining the permissiveness of a cell for a virus that is a member of...
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8423350 |
Segmenting text for searching
Methods, systems, and apparatus, including computer program products, for segmenting text for searching are disclosed. In one implementation, a method is provided. The method includes receiving...
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8420311 |
Method to block the infection by flaviviruses, molecules and uses
The present invention is related to a method for blocking the infection of cells by dengue virus, based on interfering the direct interaction of the viral envelope protein with a cellular receptor...
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8420104 |
Lentiviral gene transfer vectors and their medicinal applications
The present invention relates to the design of gene transfer vectors and especially provides lentiviral gene transfer vectors suitable for either a unique administration or, for iterative...
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8420076 |
Therapy or prophylaxis of Klebsiella pneumoniae infections with a lytic bacteriophage specifically against the K. pneumoniae
A therapy or prophylaxis of K. pneumoniae infections with a lytic bacteriophage specifically against K. pneumoniae, provides a lytic bacteriophage (DSM 24329) to a K. pneumoniae infected organism...
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8416405 |
Raman chemical imaging of implantable drug delivery devices
A system and method of determining an attribute of a biological tissue sample or a drug delivery device. A sample is illuminated with substantially monochromatic light to thereby generate Raman...
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8415131 |
M13 bacteriophage as a chemoaddressable nanoparticle for biological and medical applications
Reactive and modified M13 bacteriophages, and methods of making and using the same, are generally provided. The reactive M13 bacteriophage can include a alkyne functional group covalently attached...
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8409562 |
Chimeric vaccine antigens against classical swine fever virus
The current invention describes chimeric vaccine antigens against the virus that causes the Classic Swine Fever (CSFV). Such vaccine antigens are based on viral subunits coupled to proteins able to...
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8409526 |
Cellulose substrates, compositions and methods for storage and analysis of biological materials
The invention provides a method and article for storing genetic material or analytes from a biological sample by contacting said biological sample with a cellulose substrate comprising structural...
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8399187 |
Identifying virally infected and vaccinated organisms
This document provides methods and materials related to assessing organisms for the presence or absence of anti-virus antibodies. For example, this document provides methods and materials that can...
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8394581 |
Test method on feline vaccinated with feline immunodeficiency virus vaccine, and antigen for use in the test
Since FIV-vaccinated cats produce antibodies against FIV, distinguishing them from FIV-infected cats is difficult by serological diagnostic methods using FIV and FIV-derived substances. The present...
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8394648 |
Method of fabrication of photonic biosensor arrays
This invention relates to a method for the fabrication of photonic biosensor arrays and applications of arrays produced by the method in the biomedical field. A method for the fabrication of a...
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8394384 |
Recombinant avian influenza vaccine and uses thereof
The present invention encompasses influenza vaccines, in particular avian influenza vaccines. The vaccine may be a subunit vaccine based on the hemagglutinin of influenza. The hemagglutinin may be...
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8394386 |
Sequential delivery of immunogenic molecules via adenovirus and adeno-associated virus-mediated administrations
An immunogenic regimen is provided. The regimen involves sequential administration of a recombinant adenoviral vector and a recombinant adeno-associated viral vector, each of which delivers a...
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8394385 |
Optimized early-late promoter combined with repeated vaccination favors cytotoxic T cell response against recombinant antigen in MVA vaccines
The invention is drawn to compositions and methods for the induction of a strong CD8 T cell response to a specific antigen(s). The combination of an early/late hybrid promoter directing strongly...
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8388935 |
Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia,...
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8389706 |
Vaccines for human papilloma virus and methods for using the same
Improved anti-HPV immunogens and nucleic acid molecules that encode them are disclosed. Immunogens disclosed include those having consensus HPV 18 E6 and E7. Pharmaceutical composition, recombinant...
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8389208 |
Biological indicator
A kinase is used in a biological indicator for validation of treatment processes designed to reduce the amount or activity of a biological agent in a sample. The indication can be used for...
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8389217 |
Human papilloma virus (HPV) detection using nucleic acid probes, microbeads and fluorescent-activated cell sorter (FACS)
The present invention relates generally to the field of diagnostic and detection assays. More particularly, the present invention provides methods, and reagents including biochips for detecting the...
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8389209 |
Test device for rapid diagnostics
Devices for detecting analytes or analogues thereof in a biological sample are disclosed. The device includes a solid support. The solid support has several juxtaposed zones. The sample is able to...
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8388979 |
Polypeptide having affinity for envelope virus constituent and use thereof in transferring substance into cell
Delivery proteins are provided for transferring a protein, antibody or foreign substance into a cell without impairing the function or structure thereof. Further, methods of transferring a foreign...
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8389299 |
Photonic biosensor arrays
This invention relates to photonic biosensor arrays in particular employing plasmon resonance based sensing, and to methods and apparatus for reading such arrays. A biosensor array for plasmon...
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8383115 |
Engineered scFv against bovine herpes virus type I
The present disclosure describes a single chain variable fragment (scFv) that binds BHV-1 virus comprising a light chain variable region, a linker and a heavy chain variable region. The disclosure...
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8383335 |
Method for diagnosis and monitoring of viral infection by analysis of viral transrenal nucleic acids in urine
The present invention relates to methods for diagnosis or monitoring of viral infection by detecting the presence of transrenal viral nucleic acids or nucleic acids of viral origin in urine sample,...
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8383121 |
Monoclonal antibodies specific to hemagglutinin and neuraminidase from influenza virus H5-subtype or N1-subtype and uses thereof
Monoclonal antibodies and related binding proteins that bind specifically to the envelope glycoprotein of H5 subtypes or neuraminidase glycoprotein of N1 subtypes of avian influenza virus (AIV) are...
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8383334 |
Laminar library screen
Described is a method of screening libraries of variant proteins produced in plant leaves using a plant viral vector to identify a gene of interest comprising, inoculating leaves with a library of...
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8383333 |
HBV precore protein capable of forming particles
There is provided a HBV precore protein having an ability of forming particles, and a means for determining it. A novel HBV precore protein that forms the virus (like) particles of HBV was...
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8377678 |
Methodology for detection, enumeration, propagation and manipulation of bacteriophages
A method to propagate, enumerate and quantify bacteriophage(s) in a water sample or other aqueous sample was designed which contains ingredients to stimulate the growth of select bacterial species...
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8373206 |
Biosensor apparatuses and methods thereof
A biosensor has one or more field effect transistors each comprising a source region and a drain region separated by a channel region and a gate positioned offset and spaced from the channel...
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8372648 |
Optical reporter compositions
This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to...
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8367315 |
Inactivation of reverse transcriptases by azido-diarylpyrimidines
Azido-diarylpyrimidine (azido-DAPY) compounds, and compositions containing such compounds, are provided. In addition, methods of using azido-diarylpyrimidines to inactivate reverse transcriptases,...
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8367061 |
Anti-idiotype monoclonal antibodies mimicking the HIV gp120 CD4-binding (CD4bs)
Novel anti-idiotype monoclonal antibodies are described which are capable of specifically reacting with the idiotype of human anti-gp120 antibodies, of inhibiting the binding between the gp120...
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8367316 |
Human gastrointestinal stem cell-derived primary intestinal epithelial cell system and methods of use thereof
The present invention relates to an intestinal primary epithelial cell system for detecting gastrointestinal segment-specific activation or suppression of a Toll-like receptor (TLR) by a target...
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8367317 |
Variants of hepatitis B virus with resistance to anti-viral nucleoside agents and applications thereof
The present invention relates generally to viral variants exhibiting reduced sensitivity to particular agents and/or reduced interactivity with immunological reagents. More particularly, the...
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8367391 |
Method for detecting or determining abnormal prion protein associated with transmissible spongiform encephalopathy in blood-derived specimen or body fluid-derived specimen
A pretreatment method of a specimen used for detecting or determining abnormal prion protein (PrPres) associated with transmissible spongiform encephalopathy (TSE), wherein (1) a specimen which had...
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8361708 |
Human virus causing severe acute respiratory syndrome (SARS) and uses thereof
The present invention relates to an isolated novel virus causing Severe Acute Respiratory Syndrome (SARS) in humans (“hSARS virus”). The hSARS virus is identified to be morphologically and phy...
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8364409 |
Method and composition for rapid viability testing of cells
The present invention relates to a method for rapidly monitoring a stress response of a cell to a stressor and determining the magnitude of the stress response; a method for rapidly detecting the...
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8349582 |
High-efficiency viable sampler for ultrafine bioaerosols
Exemplary embodiments provide bioaerosol detection systems and methods for detecting bioaerosols. In one embodiment, the bioaerosol detection system can include a humidifier to increase the...
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8349606 |
Lentiviral vectors for the preparation of immunotherapeutical compositions
The invention relates to an immunogenic composition comprising a recombinant vector characterized in that it comprises a polynucleotide comprising the cis-acting central initiation region (cPPT)...
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