|
Match
|
Document |
Document Title |
|
|
6692965 |
Isolation of living cells and preparation of cell lines based on detection and quantification of preselected cellular ribonucleic acid sequences
The invention is directed to reliable and efficient detection of mRNAs as well as other RNAs in living cells and its use to identify and, if desired, separate cells based on their desired...
|
|
|
6692942 |
Single-chain polypeptides for targeted delivery of nucleic acids
The present invention is directed to a method of in vivo and ex vivo gene delivery, for a variety of cells. More specifically, it relates to a novel carrier system and method for targeted delivery...
|
|
|
6689611 |
Modified Streptomyces host cells for increased avermectin production and methods of making the same
The present invention is directed to compositions and methods for producing avermectins, and is primarily in the field of animal health. The present invention relates to the identification and...
|
|
|
6686174 |
Method and constructs for inhibiting protein expression in bacteria
A method of inhibiting the translation of bacterial mRNA is disclosed. The method comprises overexpressing in a bacterium an mRNA which contains a sequence which is complementary to the...
|
|
|
6683232 |
Production of &ggr linolenic acid by a &Dgr 6-desaturase
Linoleic acid is converted into γ-linolenic acid by the enzyme Δ6-desaturase. The present invention is directed to isolated nucleic acids comprising the Δ6-desaturase gene. More particularly,...
|
|
|
6682908 |
Mouse growth hormone secretagogue receptor
A mouse growth hormone secretagogue receptor has been isolated, cloned and sequenced. This receptor is characteristic of the G-protein family of receptors. Mouse growth hormone secretagogue...
|
|
|
6682924 |
Protease variants and compositions
The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved...
|
|
|
6680380 |
Nucleic acids encoding mammalian interleukin-1&zgr , related reagents and methods
Nucleic acids encoding mammalian, e.g., primate, IL-1ζ, purified IL-1ζ polypeptides and fragments thereof. Binding proteins, e.g., antibodies, both polyclonal and monoclonal, are also provided....
|
|
|
6677442 |
Nucleic acid encoding human REV1 protein
The present invention relates to a human cDNA homologous to the yeast REV1 gene. The sequence of human REV1 (hREV1) gene is described.
|
|
|
6676949 |
Two-step immunization procedure against Chlamydia infection
A host is immunized against infection by a strain of Chlamydia by initial administration of an attenuated bacteria harbouring a nucleic acid encoding a Chlamydia protein followed by administration...
|
|
|
6677139 |
Methods for production of proteins in host cells
The present invention provides methods for the production of proteins, particularly toxic proteins, in host cells. The invention provides methods which use a fusion protein comprising a chaperonin...
|
|
|
6673590 |
Multiply-substituted protease variants with altered net charge for use in detergents
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro...
|
|
|
6673988 |
Plant lipases
This invention relates to an isolated nucleic acid fragment encoding a lipase. The invention also relates to the construction of a chimeric gene encoding all or a portion of the lipase, in sense or...
|
|
|
6673915 |
Nucleic acid encoding monocyte chemotactic protein 4
Substantially pure nucleic acid molecules encoding the monocyte chemotactic proteins MCP-4 and MCP-5. These molecules and the polypeptides they encode are useful in treating diseases or conditions...
|
|
|
6670526 |
Arabidopsis ESD4 gene and method to control flowering time
The EARLY SHORT DAYS 4 gene ESD4 of Arabidopsis thaliana, and homologues from other species, and manipulation and use thereof in plants to influence timing of flowering of the plants.
|
|
|
6664097 |
Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide
The present invention provides isolated β-Glucuronidase (GUS) having activity at acidic pH and nucleic acids encoding the same. The nucleic acids may be isolated from any suitable species, and in...
|
|
|
6664085 |
Isolated human calcium/calmodulin (CaMk) dependent kinase proteins
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically...
|
|
|
6664082 |
Genetically engineered L-sorbose reductase-deficient mutants
The present invention provides a genetically engineered microorganism belonging to the genus Gluconobacter or Acetobacter, which has an engineered gene for the biological activity of reducing...
|
|
|
6664447 |
Tomato gene.Sw-5 conferring resistance to Tospoviruses
The present invention relates to an isolated plant nucleic acid which confers resistance to Tospoviruses as well as expression systems, host cells, and transgenic plants transformed with such a...
|
|
|
6660848 |
Allelic variant of human STAT3
A predominant allelic variant of the human STAT 3 protein, the cDNA sequence encoding it, its use in therapy and/or in diagnosis of autoimmune and/or inflammatory diseases, as well as...
|
|
|
6660274 |
Surface antigens and proteins useful in compositions for the diagnosis and prevention of lyme disease
A novel isolated Borrielia burgdorferi sensu lato surface antigen is characterized by a relative molecular mass of 39.5 kDa. This antigen is expressed in vitro by spirochetes of a B. burgdorferi...
|
|
|
6660496 |
Nucleic acid molecules encoding a KOR3 kappa opioid receptor and the methods of producing the encoded receptor
The subject invention provides recombinant nucleic acid molecule which encodes a kappa 3 opioid receptor, and the receptor encoded thereby. The subject invention further provides related...
|
|
|
6656478 |
Cross-protective salmonella vaccines
The present invention relates to a method of protecting pigs against disease caused by infection by heterologous serotypes of Salmonella including but not limited to S. typhimurium comprising...
|
|
|
6653136 |
Apparatus for, and method of, introducing a substance into an object
The invention relates to an apparatus for and method of introducing a substance into an object, particularly into a cell or cellular material. In a preferred arrangement apparatus receives the cell...
|
|
|
6645738 |
DNA molecules encoding the melanocortin 5 receptor protein from rhesus monkey
The present invention relates to rhesus monkey DNA molecules encoding the melanocortin-5 receptor protein, recombinant vectors comprising DNA molecules encoding rhesus MC-5R, recombinant host cells...
|
|
|
6645739 |
Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
The present invention provides novel expression systems for producing desired polypeptides in certain strains of yeast. The present invention further provides methods for producing polypeptide...
|
|
|
6642436 |
DNA encoding for plant digalactosyldiacylglycerol galactosyltransferase and methods of use
The cDNA encoding digalactosyldiacylglycerol galactosyltransferase (DGD1) is provided. The deduced amino acid sequence is also provided. Methods of making and using DGD1 to screen for new...
|
|
|
6642011 |
Human protease and use of such protease for pharmaceutical applications and for reducing the allergenicity of non-human proteins
The present invention relates to a method of producing novel improved protein mutant which produce low allergenic response in humans compared to the parent of that mutant. Specifically, the present...
|
|
|
6641809 |
Method of regulating cellular processes mediated by B7 and CD28
The invention identifies the B7 antigen as a ligand that is reactive with the CD28 receptor on T cells. Fragments and derivatives of the B7 antigen and CD28 receptor, including fusion proteins...
|
|
|
6638733 |
G-protein coupled receptors amplified in breast cancer
The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of...
|
|
|
6635750 |
B7-H2 nucleic acids, members of the B7 family
B7-like polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated, full-length B7-like proteins, the invention further provides isolated B7-like fusion proteins,...
|
|
|
6635741 |
G-protein coupled receptor BCA-GPCR-3
The invention provides isolated nucleic acid and amino acid sequences of four novel G-protein coupled receptors that are amplified in breast cancer cells, antibodies to such receptors, methods of...
|
|
|
6635457 |
Selection for more efficient transformation host cells
This invention provides methods for producing and selecting host cells that better survive transformation treatment by subjecting host cells to conditions that alter them, subjecting the altered...
|
|
|
6632673 |
Directing the ratio of B2:B1 avermectins in Streptomyces avermitilis host cells
The present invention relates to polynucleotide molecules comprising nucleotide sequences encoding an aveC gene product, which polynucleotide molecules can be used to alter the ratio or amount of...
|
|
|
6629038 |
Method and system for identifying commercially distributed organisms
A method of marking individuals of commercially distributed organism or organisms and offspring thereof is disclosed. The method is effected by genetically marking a plurality of individuals of the...
|
|
|
6623964 |
Method for treatment of an aqueous flux by electropulsation of a field parallel to the flow, pulsation chamber and uses thereof
The invention concerns a method for treating an aqueous flow colonized by cells with a pulsed electric field applied to a flow, characterized in that the applied field is substantially parallel to...
|
|
|
6623950 |
Modified enzymes having polymer conjugates
The present invention relates to polypeptide-polymer conjugates having added and/or removed one or more attachment groups for coupling polymeric molecules on the surface of the polypeptide...
|
|
|
6623942 |
Macrophage inflammatory protein-4 (MIP-4) polynucleotides
There are disclosed therapeutic compositions and methods using isolated nucleic acid molecules encoding a human myeloid progenitor inhibitory factor-1 (MPIF-1) polypeptide (previously termed MIP-3...
|
|
|
6620912 |
Dendritic enriched secreted lymphocyte activation molecule
The present invention relates to a novel human protein called Dendritic Enriched Secreted Lymphocyte Activation Molecule, and isolated polynucleotides encoding this protein. Also provided are...
|
|
|
6620608 |
Isolated human synthase proteins
The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically...
|
|
|
6617163 |
Polynucleotides for mutagenesis in fungus comprising a functional gene in magnaporthe and an impala transposon
The invention concerns a new tool for efficient mutagenesis enabling the generation of a collection of mutants in fungi by random insertion of a characterized Fusarium oxysporum Impala transposon...
|
|
|
6617128 |
Nucleic acid molecules encoding proteins which impart the adhesion of neisseria cells to human cells
Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid...
|
|
|
6617132 |
Human cystatin E polynucleotides
Disclosed is a human CysE polypeptide and DNA (RNA) encoding such polypeptide. Also provided is a procedure for producing such polypeptide by recombinant techniques. Also disclosed are methods for...
|
|
|
6617493 |
Nucleotide sequence encoding soybean vestitone reductase
This invention relates to an isolated nucleic acid fragment encoding soybean enzymes that catalyze steps in biosynthesis of isoflavones, the enzyme a member selected from the group consisting of...
|
|
|
6613552 |
Biocatalytic synthesis of shikimic acid
A bioengineered synthesis scheme for the production of shikimic acid from a carbon source is provided. Methods of producing shikimic acid from a carbon source based on the synthesis scheme are also...
|
|
|
6613891 |
Polynucleotides that encode bovine inhibin
Recombinant nucleic acid molecules encoding 58 kD, 43 kD, 31 kD, 20 kD and 15 kD bovine inhibin and bovine inhibin subunits are disclosed. Vectors, host cells comprising recombinant nucleic acid...
|
|
|
6610514 |
Yeast vector and method of producing proteins using the same
An object of the present invention is to provide a vector which can be integrated into a yeast chromosome in a high number of copies. Another object of the present invention is to provide a...
|
|
|
6610529 |
Recombinant bacterial system with environmentally limited viability
Disclosed is an Environmentally Limited Viability System (ELVS) for microorganisms based on differences between permissive and non-permissive environments. Viability of the microorganisms are...
|
|
|
6610515 |
Feline granulocyte colony-stimulating factor
The present invention provides a medicine which promotes the production of neutrophiles in case the number of the neutrophiles decreases upon treating the tumor of a cat, and does not have...
|
|
|
6610478 |
Phenotypic conversion of cells mediated by external guide sequences
Disclosed are a method and compositions for delivering nucleic acids to bacterial cells. The method does not require manipulation of the bacteria and is therefore particularly suited to delivery of...
|