|
Match
|
Document |
Document Title |
|
|
7524327 |
Light activated gene transduction using long wavelength ultraviolet light for cell targeted gene delivery
In accordance with the present invention, methods are provided for treating a patient through the use of ultraviolet light activated gene therapy. Embodiments of the present invention include...
|
|
|
7220571 |
Escherichia coli strains which over-produce L-threonine and processes for the production of L-threonine by fermentation
The present invention relates to the fields of microbiology and microbial genetics. More specifically, the invention relates to novel bacterial strains and processes employing these strains for the...
|
|
|
7208317 |
In Vitro mutagenesis, phenotyping, and gene mapping
Cellular libraries useful for in vitro phenotyping and gene mapping. In a representative approach, a method for preparing a homozygous cellular library includes the steps of providing a...
|
|
|
7132285 |
Apoptotic entities for use in treatment of neurodegenerative and other neurological disorders
Treatment and/or prophylaxis, in mammalian patients, of neurodegenerative and other neurological medical disorders is effected by administering to the patient effective amounts of apoptotic bodies...
|
|
|
7105292 |
Screening methods used to identify compounds that modulate a response of a cell to ultraviolet radiation exposure
The cellular response to ultraviolet radiation exposure has been characterized on the molecular level through the use of high density gene array technology. Nucleic acid molecules and protein...
|
|
|
6843961 |
Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
Methods and apparatuses are provided for inactivation of pathogens in fluids containing blood products. Preferred methods include the steps of adding an effective, nontoxic amount of a...
|
|
|
6455257 |
Designer diseases
An apparatus suitable for making a designer disease is disclosed. The apparatus comprises first, second, and third containers, each having two sections, I and II, separated by a semipermeable...
|
|
|
6413765 |
Genetically modified lactic acid bacteria having modified diacetyl reductase activities
Genetically modified lactic acid bacteria having a reduced or lacking or enhanced diacetyl reductase activity, acetoin reductase activity and/or butanediol dehydrogenase activity are provided. Such...
|
|
|
6204006 |
Microbial strains producing sphingolipid bases
Microbial strains capable of producing enhanced levels of sphingosine, dihydrosphingosine, phytosphingosine and/or derivatives thereof are disclosed. Additionally, there are disclosed methods based...
|
|
|
6132989 |
Methods and compositions for enhanced stability of non-adenoviral DNA
The invention provides compositions of a non-adenoviral vector containing a polynucleotide sequence encoding adenoviral pTP operationally linked domain. The invention also provides compositions of...
|
|
|
5928866 |
Method for preparing mutant genes
This invention provides A method for preparing mutant genes, which comprises the steps of constructing a recombinant plasmid DNA by inserting a gene fragment into a plasmid DNA having a...
|
|
|
5856141 |
Process for manufacturing cyclosporin a by highly productive fusant strain
The present invention relates to a process for making a highly productive fusant of Tolypocladium inflatum, a producing strain of cyclosporin A with immunosuppressive properties wherein the...
|
|
|
5849539 |
Thymidine kinase-lacking ouabain-resistant chicken hybridoma
The thymidine kinase-lacking hybridoma of the invention has resistance to oaubain and an Ig-producing ability and is formed by fusing a chicken B lymphoblast cell with an immunized chicken spleen...
|
|
|
5834182 |
Method for increasing transduction of cells by adeno-associated virus vectors
This invention includes methods for increasing the efficiency of transduction of cells, including non-dividing cells, by recombinant AAV vectors. The methods utilize agents that alter certain...
|
|
|
5804435 |
Method for obtaining organic solvent-resistant microorganisms and organic solvent-resistant microorganisms obtainable by the method
The present invention provides a method for obtaining organic solvent resistant microorganisms which comprises subjecting a microbial parent strain to mutagenesis and then to selective cultivation...
|
|
|
5736383 |
Preparation of Pichia methanolica auxotrophic mutants
Methods for preparing Pichia methanolica cells having auxotrophic mutations are disclosed. The methods comprise the steps of (a) exposing P. methanolica cells to mutagenizing conditions, (b)...
|
|
|
5578464 |
E. coli secretory strains
Strains of E. coli are provided which are capable of secreting heterologous recombinant proteins through the outer cell wall and directly into the culture medium. Methods are also provided for...
|
|
|
5538890 |
Self-delimiting fungal mutants, bioherbicidal compositions thereof, method of preparing thereof and method of using thereof for weed control
A broad spectrum biological herbicide comprises a mammal-sparing bioherbicide fungal mutant, e.g., a S. sclerotiorum mutant, of limited survival time and geographical dissemination characteristics...
|
|
|
5506124 |
Process for preparing glucanase resistant yeast mutants
Three dimensional glucan matrix compositions are prepared by separating growing yeast from its growth medium, subjecting the yeast with cell walls intact to an alkali material, thereby extracting...
|
|
|
5217888 |
Yeast with high content of arginine
The present invention relates to yeast with a high arginine content which belongs to Kluyveromyces polysporus and has resistance to ethionine.
|
|
|
5210033 |
Process for preparing and selecting hyperproducing microorganism strains used for the process for producing streptovaricin C
Disclosed is a method for selecting a mutant strain belonging to the genus Streptomyces which is a hyper-producer of Streptovaricin C superior to those know heretofore. This is accomplished by...
|
|
|
5079154 |
Mutant resistant to cell membrane synthesis inhibitor and process for preparing the same
A mutant of an extracellular enzyme-producing microorganism belonging to genus Bacillus, which is resistant to a cell membrane synthesis inhibitor, including vancomycin and ristocetin, is...
|
|
|
4935366 |
Method of obtaining cellulase deficient strains of white-rot fungi
A method is described of obtaining cellulase deficient strains which have great ability to degrade lignin at the same time. The method comprises crossing a homokaryotic cellulase deficient mutant...
|
|
|
4859594 |
Microorganisms for biodegrading toxic chemicals
This invention relates to novel microorganisms separated from natural environments and purified and genetically modified, process for immobilizing these microorganisms by affixing then to...
|
|
|
4851348 |
Biologically pure escherichia coli cell line which is a deoR.sup.- mutant and which is more transformation efficient with foreign plasmids than deoR.sup.+ escherichia coli cell lines, processes for obtaining these cell lines, methods of use
A method for obtaining E. coli cell lines which carry the deoR mutation is described, as well as the cell lines themselves. These cell lines are useful in cell transfection and transformation, as...
|
|
|
4751348 |
Nicotiana plants with both altered polyamine levels and flower structures and method for obtaining these plants
Plant cell lines with altered flower structures, and altered plant male and/or female sterility/fertility, and altered polyamine synthesis have been isolated using a UV mutagenizing light,...
|
|
|
4568644 |
Fermentation method producing ethanol
Ethanol is the major end product of an anaerobic, thermophilic fermentation process using a mutant strain of bacterium Clostridium thermosaccharolyticum. This organism is capable of converting...
|
|
|
4560662 |
Streptomyces antibioticus ATCC 31771 and process for obtaining same
The fermentation of a substrate selected among erythronolide B, erythronolide A and erythronolide A oxime with a novel mutant, Streptomyces antibioticus ATCC 31771, obtained from an industrial...
|
|
|
4540662 |
Semisynthetic macrolidic antibiotics, intermediate compounds for their preparation and related pharmaceutical compositions containing compounds for their preparation and related pharmaceutical compositions containing them
From the fermentation carried, out with mutants blocked in the synthesis respectively of erythromycin and of oleandomycin, namely Streptomyces erythreus ATCC 31772 and Streptomyces antibioticus...
|
|
|
4492755 |
Process for isomerizing L-mannose to L-fructose
Process for preparing L-fructose from L-mannose by contacting L-mannose with L-mannose isomerase produced by a mutant microorganism selected from the group consisting of the genera Escherichia,...
|
|
|
4473644 |
Acid stable protease from mutants of genus Rhizopus
Process for the preparation of acid stable protease having a broad activity spectrum by culturing selected mutants of Rhizopus rhizopodiformis CBS 227.75 under aerobic conditions in a nutrient...
|
|
|
4467033 |
Process for oxidizing L-sorbitol to L-fructose
Process for preparing L-fructose from L-sorbitol by contacting L-sorbitol with D-iditol dehydrogenase produced by a mutant microorganism of the genus Pseudomonas cultivated in the absence of an...
|
|
|
4456588 |
Method of the preparation of improved mutant strain of Bordetella bronchiseptica useful as live attenuated vaccine for prophlaxis of B. bronchiseptica infection
A method for the preparation of a new mutant strain of Bordetella bronchiseptica having a plural of hereditary chromosomal markers of at least temperature-sensitivity and urease negative, more...
|
|
|
4431737 |
Process for the production of alpha-galactosidase and uses of the enzyme thus obtained
The enzyme alpha-galactosidase is prepared from a constitutive mutant of the strain Saccharomyces cerevisiae NRRL-Y-12057, said mutant being marked by the identification number NRRL-Y-12533.
|
|
|
4415660 |
Method of making a cloning vector
A cloning vector useful in recombining DNA (i.e. recombinant DNA studies) is made by mutagenesis of a satellite bacteriophage P4 wt or P4 vir 1 and subsequent separation and purification of the...
|
|
|
4368269 |
Process for producing food proteins of fungal origin of from multicellular organisms fermentation apparatus and proteins so-produced
The process consists of cultivating, at a temperature below 28° C., the fungus Trichoderma album in liquid nutrient media, the pH of said media being kept at a value comprised between about 3.7...
|
|
|
4362815 |
Process for the preparation of defective mutants of microorganisms
For the production of 17-C-steroid-α-propionic acid compounds by microbial side chain degradation on 17-C-side chain steroid substrates wild strain microorganisms selected in predetermined manner...
|
|
|
4332899 |
Process for producing maltase
Maltase is produced by growing a mutant of the yeast strain Saccharomyces italicus capable of growing in a growth medium utilizing sucrose as the carbon source. Mutants of Saccharomyces italicus...
|
|
|
4324860 |
Lactate dehydrogenase mutants of Streptococcus mutans
Mutant strains have been isolated from Streptococcus mutans strain BHT-2(str) which are characterized by a single point mutation in the structural gene for the enzyme, L(+) lactate dehydrogenase,...
|
|
|
4211846 |
Processes for the manufacture of D(-)-3-hydroxybutyric acid and D(-)-3-hydroxybutyric acid producing mutants
The invention relates to a process of manufacturing D(-)-3-hydroxybutyric acid by breeding microorganisms capable of producing said acid in a nutrient medium containing certain specific carbon...
|
|
|
4138291 |
Microbiological methods
The invention relates to a method of obtaining selected bacterial strains which can convert an assimilable carbon source selected from carbohydrates, methanol, ethanol, glycerin, carbon dioxide and...
|
|
|
4115197 |
Procedure for obtaining penicillium species mutants with improved ability to synthesize mycophenolic acid
A procedure for efficiently obtaining higher mycophenolic-acid-producing mutants from mycophenolic-acid-producing strains of the genus Penicillium by selecting mutants which are resistant to...
|
|
|
4070243 |
Method for distinguishing subpopulations in a population of morphologically indistinguishable cells
A method for identification of cell subpopulations in a population of cells which are morphologically alike, based on the ability of selected strains of bacteria to bind to the cell surface when...
|
|
|
4054489 |
Method of preparing l-glutamic acid and its sodium salt
The method of preparing L-glutamic acid and its sodium salt by growing, on a nutrient medium containing sources of nitrogen, carbon and mineral salts a strain producent of L-glutamic acid,...
|
|
|
RE29152 |
Process for the enzymatic isomerization of dextrose to levulose
Process for the production of xylose (dextrose) isomerase by means of a mutant strain of Streptomyces that proliferates in a culture medium that may be free of xylose. The xylose (dextrose)...
|
|
|
3986933 |
Method of preparing yeasts enriched in L-lysine and capable of excreting organic acids
A method of preparing a yeast enriched in L-lysine and capable of excreting an organic acid, such as citric acid, and possibly also isocitric and glutamic acids, when cultivated on a...
|
|
|
3930946 |
Yeasts
A process for the preparation of a stable diploid of Candida lipolytica which comprises (a) in a first stage, separately cultivating two haploid strains of Candida lipolytica of opposed sign in a...
|
|
|
3923601 |
Process for the manufacture of cephalosphorin C
Process for the manufacture of Cephalosporin C by cultivating mutants of Emericellopsis-Cephalosporium in which the metabolism and/or biosynthesis of organic sulfur compounds is disturbed.
|
|
|
3855063 |
PROCESS FOR PRODUCING A MICROBIAL PROTEINOUS SUBSTANCE
A microbial proteinous substance useful in manufacturing various foodstuffs, animal feed and fish culturing feed can be prepared from a hydrocarbon-assimilating yeast of genus Candida by mutating...
|
|
|
3255095 |
Mutant detection method
|