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8173390 |
Method for facilitating fermentation of high solids compositions
The present invention features a method for facilitating the fermentation of a high solids composition. The method involves subjecting the high solids composition to granular starch hydrolyzing...
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8173776 |
Recombinant gelatins
The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBE monomer sequence that are of particular use in several applications involving cell attachment...
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8168203 |
Shigella protein antigens and methods
The present invention relates to protein antigens IcsP2 and SigA2 from Shigella that are common among numerous Shigella types and species and which can protect against shigellosis or other enteric...
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8168945 |
Method for generation and use of isotopic patterns in mass spectral data of simple organisms
A method for identifying a biological analyte that is affected by a stressor is disclosed in which two substantially identical biological samples are provided, with a first sample being a control...
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8163515 |
Eukaryotic Microorganisms for producing lipids and antioxidants
Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and use.
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8163517 |
Organic material production system using biomass material and method
An organic material production system using biomass material includes: a hydrothermal decomposition apparatus (13) that causes the biomass material (11) and hot compressed water (12) to...
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8163516 |
Selection of ADH in genetically modified cyanobacteria for the production of ethanol
The present invention discloses genetically-modified cyanobacteria with ethanol-production capabilities enhanced over the currently-reported art, and methods of making such cyanobacteria. The...
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8158371 |
Assay for antibodies to Mycobacterium paratuberculosis
A method of detecting an immune response to a paratuberculosis-specific antigen, comprising incubating a sample from a subject with the paratuberculosis-specific antigen and detecting the presence...
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8158756 |
Recombinant gelatins
The invention concerns a recombinant CBE gelatin and recombinant gelatins having multimers of the CBE monomer sequence that are of particular use in several applications involving cell attachment...
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8158404 |
Reduced by-product accumulation for improved production of isobutanol
The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In...
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8158399 |
Extracellular bioreduction
A method for processing environmental or industrial samples to remove, reclaim or otherwise reduce the level of chemical species present in the sample that act as redox active species. The redox...
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8158402 |
Acetoin high-yield Bacillus pumilus strain
A high-yield bacterial strain for producing acetoin named Bacillus pumilus XH195 has been deposited in a microorganism deposit center in Germany. The deposit number is DSM 16187. The bacteria of...
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8153415 |
Reduced by-product accumulation for improved production of isobutanol
The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In...
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8153411 |
Dehalogenases, nucleic acids encoding them and methods for making and using them
The invention relates to haloalkane dehalogenases and to polynucleotides encoding the haloalkane dehalogenases. In addition methods of designing new dehalogenases and method of use thereof are also...
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8147847 |
Shigella protein antigens and methods
The present invention relates to protein antigens IcsP2 and SigA2 from Shigella that are common among numerous Shigella types and species and which can protect against shigellosis or other enteric...
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8148102 |
Sequences for FK228 biosynthesis and methods of synthesizing FK228 and FK228 analogs
Polynucleotides encoding the polypeptides involved in biosynthesis of FK 228 and those involved in synthesis of a novel FK228 analog, thailandepsin are disclosed herein. Also provided are methods...
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8148103 |
Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
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8143021 |
Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
The present invention relates to isolated polypeptides having cellulolytic enhancing activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
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8143020 |
Enhanced metabolite generation
The present invention relates to the enhanced production of metabolites by a process whereby a carbon source is oxidized with a fermentative microbe in a compartment having a portal. An electron...
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8143040 |
Process for whole cell saccharification of lignocelluloses to sugars using a dual bioreactor system
The present invention describes a process for saccharification of lignocelluloses to sugars using whole microbial cells, which are enriched from cultures inoculated with paper mill waste water,...
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8137951 |
Methods for producing hyaluronan in a recombinant host cell
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
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8138324 |
Expression system for proteins
The invention provides a novel system for the tunable expression of nucleic acids encoding e.g., polypeptides such as recombinant proteins in prokaryotic systems. The system is based on the ability...
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8133493 |
Regulated attenuation of live vaccines to enhance cross-protective immunogenicity
A live attenuated derivative of a pathogenic bacterium intended for use as a vaccine.
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8133715 |
Reduced by-product accumulation for improved production of isobutanol
The present invention relates to recombinant microorganisms comprising biosynthetic pathways and methods of using said recombinant microorganisms to produce various beneficial metabolites. In...
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8129139 |
Process for obtaining botulinum neurotoxin
Rapid, animal protein free, chromatographic processes and systems for obtaining high potency, high yield botulinum neurotoxin for research, therapeutic and cosmetic use.
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8129168 |
Recombinant colwellia psychrerythraea alkaline phosphatase and uses thereof
A heat labile alkaline phosphatase enzyme and methods of using the same and kits including the same are disclosed. Specifically, a nucleotide sequence of, peptide sequence of, methods of using, and...
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8129197 |
Cholesterol loaded insect cell membranes as test proteins
The invention provides for a novel cholesterol loaded insect cell membrane preparation having an increased cholesterol level as compared to physiological cholesterol levels of insect cell membranes...
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8129140 |
Thermophilic endo-glucanase and uses thereof
A novel thermophilic endo-glucanase, nucleic acid encoding the endo-glucase, and uses thereof in converting ligocellulosic material to fermentable sugars.
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8129141 |
Fibrous protein fusions and use thereof in the formation of advanced organic/inorganic composite materials
The claimed invention provides a fusion polypeptide comprising a fibrous protein domain and a mineralization domain. The fusion is used to form an organic-inorganic composite. These...
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8124390 |
Aromatic prenyltransferases, nucleic acids encoding same and uses therefor
In accordance with the present invention, a novel aromatic prenyltransferase, Orf2 from Streptomyces sp. strain CL190, involved in naphterpin biosynthesis has been identified and the structure...
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8124394 |
Polypeptides having cellobiohydrolase II activity and polynuleotides encoding same
The present invention relates to isolated polypeptides having cellobiohydrolase activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid...
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8119339 |
Heteroduplex tracking assay
A change in viral tropism occurs in many HIV positive individuals over time and may be indicated by a shift in coreceptor use from CCR5 to CXCR4. The shift in coreceptor use to CXCR4 has been shown...
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8119354 |
Cell-free assay product and method of use thereof for measuring activity of frizzled receptors
The present invention relates to cell free assays for measuring receptor activity, especially for measuring a constitutive or a non-constitutive activity of frizzled re-ceptors and uses thereof....
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8119376 |
Method for the production of lactic acid or a salt thereof by simultaneous saccharification and fermentation of starch
The present invention pertains to a method for the production of lactic acid or a salt thereof wherein starch is subjected to a process of simultaneous saccharification and fermentation, the method...
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8119378 |
Microbial alcohol production process
The invention relates to the production of alcohols by microbial fermentation, particularly to production of alcohols by microbial fermentation of substrates comprising CO. It more particularly...
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8114642 |
Method for producing vitamin K2 from culture of Bacillus natto
A method for producing vitamin K2 comprising: culturing Bacillus natto in a liquid medium to obtain a Bacillus natto culture or culture supernatant thereof, wherein the culture or culture...
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8105801 |
Starch process
The present invention relates to a process for enzymatic hydrolysis of granular starch into a soluble starch hydrolysate at a temperature below the initial gelatinization temperature of said...
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8101377 |
Protein hydrolysates and method of making
Methods of making protein hydrolysates are described. The methods may include the steps of providing a solution comprising protein, and adjusting a pH of the solution to about 10.4 or more to form...
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8101167 |
Conditioned medium and uses thereof
The invention relates to compositions containing an agent that has an irritant side effect and a conditioned cell culture medium and/or of an extract thereof, for use, e.g., in the treatment of...
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8097274 |
Skin substitutes, preparation methods and uses thereof
Provided herein are skin substitutes suitable for use in a living subject for purpose of repairing damaged tissues, methods of producing the skin substitutes and their uses. A biocomposite membrane...
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8093036 |
Methods for producing hyaluronan in a recombinant host cell
The present invention relates to methods for producing a hyaluronic acid, comprising: (a) cultivating a Bacillus host cell under conditions suitable for production of the hyaluronic acid, wherein...
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8093023 |
De-fatted soy production process and value added by-products from de-fatted soy flour
An improved process for producing de-fatted soy utilizing a de-fatted soy flour and for producing value added by-products from de-fatted soy flour wherein soybeans are de-hulled and the de-hulled...
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8093045 |
Fed-batch cell culture methods using non-animal-based hydrolysates
The invention describes improved methods and compositions for producing a recombinant protein, e.g., an antibody, in mammalian cell culture. In addition, the invention provides improved cell...
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8093034 |
Fed batch culture methods for streptococci
This invention relates to the optimization of culture conditions to improve the production of bacterial capsular polysaccharides from Streptococcus strains in fed-batch culture.
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8093061 |
Methods of determining potency of chemically-synthesized oligonucleotides
Provided herein are methods for determining potency of RNAi agents. Such methods include, but are not limited to, cell-based and cell-free assays that measure binding of an RNAi agent with Ago2 or...
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8088620 |
Optimised micro-organism strains for NADPH-consuming biosynthetic pathways
The invention relates to optimised micro-organism strains for the biotransformation production of molecules having NADPH-consuming biosynthetic pathways. The inventive strains can be used in...
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8084226 |
Method for site-specific protein modifications
A method for site-specific modification of protein molecules includes providing a protein molecule having at least first and second non-terminal Cys residues at respective first and second sites...
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8084227 |
Method for producing dipeptides
The present invention provides a method for producing a dipeptide from starting materials that are available at low costs through a route industrially advantageous and simple. Dipeptides are...
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8084235 |
Purification process for bacterial cytolysin
The present invention relates to a method for purifying bacterial cytolysins such as pneumococcal pneumolysin. A single chromatography step produces excellent purification of the cytolysin by...
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8084239 |
Preparation of a therapeutic composition
Product R, a novel therapeutic composition for treating viral infections and stimulating the immune system comprises a unique peptide having 31 amino acids and another unique peptide having 21...
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