|
Match
|
Document |
Document Title |
|
|
8182983 |
Method for determining immune system affecting compounds
The present invention relates to a method for increasing efficacy and/or possibility of therapeutic treatment of cancer, wherein any dys-regulatory mechanism, including inducing factor/s, of the...
|
|
|
8183056 |
Assay
A method for determining the risk of an individual of suffering from inflammation, opportunistic infection or disruption of immunoglobulin metabolism, comprising (a) determining the level of...
|
|
|
8183002 |
Autoantibody enhanced immunoassays and kits
The present disclosure provides immunoassays and kits for detection or quantification of an analyte of interest in a test sample that potentially contains endogenously produced autoantibodies...
|
|
|
8183353 |
Breast cancer prognostics
A method of providing a prognosis of breast cancer is conducted by analyzing the expression of a group of genes. Gene expression profiles in a variety of medium such as microarrays are included as...
|
|
|
8182746 |
Electrophoresis process using a valve system
An electrophoresis apparatus is generally disclosed for sequentially analyzing a single sample or multiple samples having one or more analytes in high or low concentrations. The apparatus comprises...
|
|
|
8183005 |
Pharmaceutical agents for treating HCV infections
The present inventors examined the inhibitory activity against HCV replicon of myriocin, fumonisin B1, and ceramide trafficking inhibitor HPA-12, which are compounds derived from microorganisms...
|
|
|
8178358 |
Serpine2 as a biomarker for IgA nephropathy
The present invention provides a method for diagnosis or prognosis of IgA nephropathy in a subject based on detection of the expression level of one or more biomarker genes selected from the group...
|
|
|
RE43389 |
Vessel for blood sampling
The present invention relates to a vessel for withdrawing blood, the vessel containing a solution which comprises a guanidinium salt, a buffer substance, a reducing agent, and/or a detergent as...
|
|
|
8178290 |
Solid support
The present invention provides a solid support for performing steps of isolation of cell or extraction and purification of nucleic acid, safely, easily, efficiently, and with high yield in the...
|
|
|
8173360 |
Cell death inhibitor
The cell death inhibitor comprising a substance capable of binding to macrophage migration inhibitory factor is useful as a preventive/therapeutic agent for, e.g., heart diseases, neurodegenerative...
|
|
|
8173388 |
Self-contained biological indicator
The disclosed invention provides a self-contained sterilization indicator for evaluating the effectiveness of a sterilization process. The sterilization indicator includes a cap configured for...
|
|
|
8175371 |
Method for imaging and differential analysis of cells
Provided are methods for determining and analyzing photometric and morphogenic features of small objects, such as cells to, for example, identify different cell states. In particularly, methods are...
|
|
|
8173103 |
Inhibition of cancer metastasis
P-Selectin on platelets and endothelium binds cell surface chondroitin sulfate (CS) proteoglycans, which are abundantly and stably expressed on the surface many cancer cells. Binding of the cancer...
|
|
|
8173359 |
Methods and apparatus and assays of bacterial spores
A sample of unknown bacterial spores is added to a test strip. The sample of unknown bacterial spores is drawn to a first sample region on the test strip by capillary action. Species-specific...
|
|
|
8173361 |
Method of determining metabolism of a test agent
A method for detecting one or more metabolites of a test agent in a tissue including: A) incubating a test agent and an enzyme within a three-dimensional structure comprising a first mold or...
|
|
|
8173602 |
Detecting CYP24 expression level as a marker for predisposition to cancer
This invention pertains to the discovery that an amplification of the CYP24 gene or an increase in CYP24 activity is a marker for the presence of, progression of, or predisposition to, a cancer...
|
|
|
8168423 |
Device for detecting nitrosothiol content in solution
A device for detecting nitrosothiol content in a solution includes at least two electrodes disposed in a housing, wherein one of the at least two electrodes is a working electrode having a...
|
|
|
8168393 |
Compositions and methods for diagnosing tumors using LEDGF/p75
The invention provides methods for diagnosing tumors in mammals using a reagent that bind to LEDGF/p75 or to a nucleic acid encoding LEDGF/p75. For example, the tumor may be located in the CNS, the...
|
|
|
8168394 |
Method for simultaneously detecting an antigen of, and an antibody against, an infectious microorganism
The invention relates to a method for detecting, in vitro, an infection with a microorganism, such as the hepatitis C virus, in a biological sample, by simultaneously detecting an antigen of this...
|
|
|
8163279 |
IL3Rα antibody conjugates and uses thereof
The present invention provides antibodies that bind to the IL-3 receptor alpha subunit alpha (Il3Rα) chain, and compositions comprising such antibodies. The present invention provides methods for ...
|
|
|
8163473 |
Method for using DNA repair capacity as a biomarker of breast cancer risk in women
The present invention presents a method for using DNA repair capacity (DRC) as a blood biomarker to calculate the risk of a female subject developing breast cancer obtained from a blood sample by...
|
|
|
8163492 |
Microfluidic device and methods of using same
A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high...
|
|
|
8163472 |
Dry analytical element capable of reducing influence of hemolysis for body fluid component measurement
It is an object of the present invention to reduce influence of hemolysis in a dry analytical element used for measurement of components in a body fluid sample such as blood. The present invention...
|
|
|
8163719 |
Regulators of the hedgehog pathway, compositions and uses related thereto
The present invention makes available, inter alia, methods and reagents for modulating smoothened-dependent pathway activation. In certain embodiments, the subject methods can be used to counteract...
|
|
|
8163475 |
Methods for diagnosis and prognosis of psychotic disorders
The invention features methods diagnostic of a psychotic disorder such as bipolar disorder or schizophrenia. The methods include obtaining a cell sample from a subject, subjecting a cell from the...
|
|
|
8163471 |
Reagent for sample analysis, kit for sample analysis and method for sample analysis
A reagent for measuring basophils and/or nucleated red blood cells in a sample, which comprises at least one fluorescent dye defined in the formula (I) or (II) is disclosed. Also disclosed are a...
|
|
|
8160821 |
Method for supporting a diagnosis of an effect of a treatment by using anthracycline anticancer drugs and a device for supporting a diagnosis for an effect of a treatment by using anthracycline anticancer drugs
A method of supporting a diagnosis of an effect of a treatment by using anthracycline anticancer drugs is disclosed. The method provides a new value for judging an effect, a judgment score, which...
|
|
|
8158377 |
Biosensor method and system based on feature vector extraction
A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a...
|
|
|
8158801 |
Violet laser excitable dyes and their method of use
The present invention provides dye compounds optimally excited at about 400 nm and have a Stokes shift of at least about 80 nm. These dyes find use in detection of analyte in a sample and the...
|
|
|
8158364 |
Methods and compositions involving nucleotide repeat disorders
The present invention concerns the methods and compositions involving nucleic acids with long repeat sequences. In some embodiments of the invention, there are methods for generating such a nucleic...
|
|
|
8158340 |
Methods for detecting conformational changes in bioentities
Described herein are methods for detecting conformational changes in bioentities.
|
|
|
8153359 |
Toxicity assay based on human blastocyst-derived stem cells and progenitor cells
An in vitro toxicity assay based on human blastocyst-derived stem cells for the detection of toxicity in the human species is provided, which enables novel detection of in vitro human toxicity for...
|
|
|
8153358 |
Selection and enrichment of proteins using in vitro compartmentalization
Compositions and methods are provided for selection and enrichment of a target gene from a library of polynucleotide sequences such as might be formed from a genome or by random mutagenesis of a...
|
|
|
8153391 |
Hydrolases, nucleic acids encoding them and methods for making and using them
Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides....
|
|
|
8153436 |
Assays for disease-associated crystals in biological samples
Methods of assaying for disease-associated crystal species in biological samples are described. Such methods involve contacting a patient sample with an excess of a detectable crystal-tagging...
|
|
|
8153081 |
Test sensor and method for manufacturing the same
According to one embodiment of the present invention, an optical-based test sensor for use in the determination of an analyte in a liquid sample is disclosed. The test sensor includes a base, a...
|
|
|
8147845 |
Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions
Reovirus can be used to selectively remove ras-mediated neoplastic cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with...
|
|
|
8148057 |
Methods, immunoassays and devices for detection of anti-lipoidal antibodies
Compositions, methods and devices for the detection of anti-lipoidal antibodies and the diagnosis of disease, for example, syphilis, are described. In particular, a method for immobilizing a...
|
|
|
8148502 |
R-ALPHA1 antitrypsin anion exchange chromatography
The present invention relates to a method for obtaining highly purified recombinant alpha1-antitrypsin (rAAT) using anion exchange chromatography, wherein a composition comprising rAAT and at least...
|
|
|
8148058 |
Method for screening allergic disease-related molecule and cell lines to be used in the method
An allergic disease-related substance is screened from candidate substances based on the reactivity to a plurality of cell lines, which are basophil-like or mast cell-like cell lines derived from...
|
|
|
8148083 |
Methods of screening for TRPM4 modulators of insulin secretion
The invention relates to methods useful in identifying candidate agents that modulate insulin secretion from an insulin secreting cell, where such molecules modulate TRPM4 activity and expression...
|
|
|
8150628 |
Establishing a biological recording timeline by artificial marking
A method and system are described for transmitting a timing estimate record responsive to a systemic flow of one or more artificial markers.
|
|
|
8148056 |
Methods of identifying modulators of GPR81 receptors
Complexes of GPR81 receptor components and ligand components, such as L-lactate or GHB, may be used as an assay reagent for screening for modulators of GPR81 receptor activity.
|
|
|
8150627 |
Methods and compositions for diagnosing lung cancer with specific DNA methylation patterns
The present invention provides a method for identification of differentially methylated genomic CpG dinucleotide sequences within genomic target sequences that are associated with cancer in an...
|
|
|
8150626 |
Methods and compositions for diagnosing lung cancer with specific DNA methylation patterns
The present invention provides a method for identification of differentially methylated genomic CpG dinucleotide sequences within genomic target sequences that are associated with cancer in an...
|
|
|
8142996 |
Mass spectrometric determination of blood enzyme activity
The invention relates to the determination of the nature and strength of enzymatic activity in blood using mass spectrometric measurement of a profile of the reaction products. The determination of...
|
|
|
8142775 |
Crystallized oxalate decarboxylase and methods of use
Oxalate decarboxylase crystals, including stabilized crystals, such as cross-linked crystals of oxalate decarboxylase, are disclosed. Methods to treat a disorder associated with elevated oxalate...
|
|
|
8142995 |
Method for assessing arteriosclerosis and diabetic nephropathy
A method for assessing arteriosclerosis comprising measuring the serotonin level in whole blood, serum or platelet-rich plasma and rating the serotonin level on such a scale that the lower it is,...
|
|
|
8142994 |
Classification, diagnosis and prognosis of acute myeloid leukemia by gene expression profiling
The present invention relates to methods of genetic analysis for the classification, diagnosis and prognosis of acute myeloid leukemia (AML). The invention provides a method for producing a...
|
|
|
8143067 |
Hydrophilic, high protein binding, low fluorescence, western blotting membrane
Hydrophilic membrane particularly suited for blotting applications, preferably Western blotting. A pre-wet hydrophobic membrane substrate, preferably made of PVDF, is contacted with a monomer...
|