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7312041 |
Methods of diagnosing cervical cancer
The invention provides reagents and methods for detecting pathogen infections in human samples. This detection utilizes specific proteins to detect the presence of pathogen proteins or abnormal...
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7309766 |
PRO5774 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7309580 |
Chromogenic plating medium for the rapid presumptive identification of Bacillus anthrasis, Bacillus cereus, and Bacillus thuringiensis
A plating medium for the presumptive identification of Bacillus cereus, Bacillus thuringiensis and/or Bacillus anthrasis that includes a nutrient base to facilitate growth of Bacillus cereus,...
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7309593 |
Attachment of molecules to surfaces
The present invention relates to methods, reagents, and substrates that can be used for, for example, immobilizing biomolecules, such as nucleic acids and proteins. In an embodiment, the present...
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7306945 |
Truncated fragments of alpha-synuclein in Lewy body disease
The application identifies fragments of alpha-synuclein in patients with Lewy Body Disease (LBD) and transgenic animal models thereof. These diseases are characterized by aggregations of...
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7306905 |
Method of identifying substances useful for promoting resistance to cell stress
The invention is directed to methods for identifying test substances useful for the prevention or treatment of diseases involving an oxidative stress. The methods involve screening assays,...
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7306910 |
Breast cancer prognostics
A method of providing a prognosis of breast cancer is conducted by analyzing the expression of a group of genes. Gene expresson profiles in a variety of medium such as microarrays are included as...
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7306936 |
Alpha-amylase variants
The invention relates to a variant of a parent Termamyl-like alpha-amylase, which variant exhibits altered properties, in particular reduced capability of cleaving a substrate close to the...
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7306929 |
Method for controlled release of enzymatic reaction components
Compositions and reaction kits are provided for controlling an enzymatic process. The compositions and kits include a substantially water-insoluble, water-permeable polymer and a poorly...
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7306923 |
Methods for identification, and compounds useful for the treatment of degenerative & inflammatory diseases
The present invention relates to in vivo and in vitro methods, agents and compound screening assays for inhibiting extra-cellular matrix degradation, including joint degenerative inhibiting and/or...
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7303921 |
Method to assay coenzyme Q10 in blood plasma or blood serum
A method is described for determining CoQ 10 concentrations in plasma samples. CoQ 10 in the plasma sample is oxidized by treating the sample with an oxidizing agent having a redox potential...
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7303894 |
Detection of phenols using engineered bacteria
Detection of phenols using engineered bacteria. A biosensor can be created by placing a reporter gene under control of an inducible promoter. The reporter gene produces a signal when a cognate...
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7303866 |
Methods of identifying an agent that modulates an interaction between 53BP1 and histone H3, and uses thereof
The present invention relates to methods of identifying modulators of an interaction between 53BP1 and histone H3 (H3). The present invention also relates to methods of use of inhibitors of an...
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7303885 |
Screening method for candidate drugs
The present invention relates to methods for screening molecules and methods to detect protein-protein interactions and means used therein. More specifically, the present invention relates to...
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7300759 |
Use of tramdorins in diagnostic and therapeutic methods
A family of transmembrane domain proteins, the tramdorins, has been identified in human, mouse and rat. A variety of uses for these proteins is contemplated, including but not limited to peripheral...
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7301067 |
Mice which are +/− or −/− for the elastin gene as models for vascular disease
Elastin, the main component of arterial extracellular matrix, was thought to have a purely structural role. Consistent with this view, elastin hemizygous mice maintain arterial extensibility by...
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7300793 |
Method for preventing the adhesion of particles
A method for the prevention of the adhesion of particles, in particular cells and cellular components in solution to surfaces, characterized in that to the solution is added at least one polyalcohol.
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7300778 |
Human proteins responsible for NEDD8 activation and conjugation
The invention relates to covalent modification of proteins through their conjugation with other proteins. More particularly, the invention relates to the modulation of such conjugation involving...
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7297502 |
Devices and methods for analyte assays with built-in result reporting using recognizable symbols
The present invention provides devices, methods and kits for detecting the presence of an analyte in a liquid sample. The invention provides devices having a positive control area covered with an...
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7297527 |
Highly productive α-amylases
The invention relates to mutant α-amylases that may be produced at high yield from recombinant microorganisms.
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7297551 |
Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics
Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for...
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7297766 |
PRO5337 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7297528 |
Alkaline protease
An alkaline protease having the following properties; a gene encoding the same; a microorganism producing the same; and washing compositions containing the same; (i) acting over a broad pH value...
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7294456 |
Mass labels
Provided herein are sets of mass labels. Each mass label in a set includes 1) a mass marker moiety; 2) a mass normalisation moiety; and 3) a cleavable linker connecting the mass marker moiety to...
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7294472 |
Method for identifying modulators of G protein coupled receptor signaling
This invention relates to methods for identifying peptides and other compounds which block or enhance G protein coupled receptor mediated signaling with high affinity and specificity and/or which...
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7294691 |
Soluble secreted α2δ-2calcium channel subunit polypeptide
The present invention relates to secreted soluble α2δ-2, α2δ-3 or α2δ-4 calcium channel subunit polypeptides and their preparation, corresponding nucleic acids, recombinant vectors and host...
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7294498 |
Glycosidase enzymes
A thermostable glycosidase enzymes derived from various Thermococcus, Staphylothermus and Pyrococcus organisms is disclosed. The enzymes are produced from native or recombinant host cells and...
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7295931 |
Deriving fixed bond information
Fixed bond information is derived. A fixed bond representation of a chemical structure is derived from a delocalized representation. A path is conceptually traced through the represented structure...
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7291705 |
PRO19645 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7291454 |
Transgenic animals and cell lines for screening drugs effective for the treatment or prevention of Alzheimer's disease
Disclosed are transgenic animals and transfected cell lines expressing a protein associated with Alzheimer's Disease, neuroectodermal tumors, malignant astrocytomas, and glioblastomas. Also...
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7291491 |
Polypeptides
The present invention provides pharmaceutical preparations for anti-inflammation, anti-infection, inhibition of cancer metastasis etc., foods such as dairy products etc., and a method for improving...
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7291462 |
TADG-15: an extracellular serine protease overexpressed in carcinomas
The present invention provides DNA encoding a TADG-15 protein as well as a TADG-15 protein. Also provided is a vector capable of expressing the DNA of the present invention adapted for expression...
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7291494 |
Regulation of target protein activity through modifier proteins
The present invention is based on the discovery that a polypeptide containing the JAB subunit or the JAM domain has peptidase activity, e.g., isopeptidase activity. The present invention provides...
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7291451 |
Modulation of pericyte proliferation
Methods and materials for modulating pericyte and epithelial cell proliferation relating to BPI protein products or inhibitors thereof are provided.
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7291707 |
PRO1337 polypeptides
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid...
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7288367 |
Non-mevalonate isoprenoid pathway
The present invention is directed to enzymes and intermediates of the non-mevalonate isoprenoid pathway downstream of 2C-methyl-D-erythritol 2,4-cyclopyrophosphate and upstream of isopentenyl...
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7288383 |
Eosinophil-derived neurotoxin as a marker for ovarian cancer
The present invention is directed to methods of identifying women at increased risk of having ovarian cancer. Identification is based upon the extent to which biological samples derived from the...
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7288413 |
Combined chemical and immunochemical fecal occult blood test
Methods for testing a fecal sample for the presence of hemoglobin, comprising performing a chemical fecal occult blood test on the sample and then performing an immunochemical fecal occult blood...
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7288368 |
Membrane receptor reagent and assay
A membrane receptor reagent and assay is disclosed in which liposomes are bound to an evanescent wave emitting surface. Membrane receptors on the liposome's fluid lipid bilayer membrane are labeled...
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7288257 |
Diagnosis and treatment of human dormancy syndrome
New methods for diagnosis of human dormancy syndrome are provided. Human dormancy syndrome is characterized by elevated serum ratio of rT3/fT3 compared to a population of normal subjects from which...
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7285385 |
Methods for analyzing animal products
The present invention provides methods for analysing animal products. In particular methods for differentiating animal products on the basis of breed origin or validating an animal product are...
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7285380 |
Methods of producing polyketide synthase mutants and compositions and uses thereof
The present invention comprises crystalline polyketide synthases, isolated non-native polyketide synthases having the structural coordinates of said crystalline polyketide synthases, and nucleic...
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7285394 |
Discovery and diagnostic methods using 5-methylcytosine DNA glycosylase
The present invention provides methods for identification of methylated, and/or potentially methylatable CpG dinucleotides in genomic DNA sequences, and methods for isolating genomic DNA sequences...
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7282325 |
Method of preparing pharmaceutical compositions
A method for the discovery of compounds suitable for the treatment and/or prophylaxis of obesity, in which the ability of the test compounds to inhibit de novo lipogenesis in mammals and/or man is...
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7282201 |
Methods of promoting the growth or differentiation of hematopoietic stem or progenitor cells by non-muscle type cofilin
This invention has as its object providing promoters of the growth and/or differentiation of hematopoietic stem cells and/or hematopoietic progenitors which are useful as therapeutics of diseases...
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7279298 |
Protein-deamidating enzyme, gene encoding the same, production process therefor, and use thereof
A novel enzyme which has an activity to release side chain carboxyl groups and ammonia from a protein by acting upon side chain amido groups in the protein. This invention relates to a method for...
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7279274 |
Method for diagnosing diabetes in a mammal
Provided are mammalian secreted and non-secreted diabetes mediating proteins, including protective and deleterious diabetes-mediating proteins, as well as polynucleotides encoding same, drug...
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7279316 |
Enzymes having glycosidase activity and methods of use thereof
The invention relates to glycosidases and to polynucleotides encoding the glycosidases. In addition methods of designing new glycosidases and method of use thereof are also provided. The...
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7279315 |
Polypeptides having glucanotransferase activity and nucleic acids encoding same
The present invention relates to nucleic acids encoding polypeptides having glucanotrans-ferase activity, nucleic acid constructs, recombinant expression vectors, recombinant host cells and methods...
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7279136 |
Metering technique for lateral flow assay devices
A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. A sample membrane is utilized having a collection region and a detection region, the...
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