|
Match
|
Document |
Document Title |
|
|
7622299 |
Bioengineered tissue substitutes
In one aspect, the invention provides methods for forming a target tissue substitute. The methods of the invention comprise the following steps: (a) providing a scaffold comprising one or more...
|
|
|
7622298 |
Method for creating perfusable microvessel systems
Microvessel networks are produced in vitro from tissue-engineered parent vessels sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems...
|
|
|
7622129 |
Nano-structured polymers for use as implants
Polymeric materials and processes for making the same are provided herein wherein said polymeric materials have nano-sized topological features or textures. These features have dimensions in...
|
|
|
7618452 |
Artificially produced, three-dimensional muscle tissue
The invention relates to a device for producing a three-dimensional circular muscle body from a carrier substance and from cell cultures incorporated therein comprising a cell culture dish ( 1 )...
|
|
|
7608455 |
Modified reconstituted basement membrane composition for assay system
A modified reconstituted extracellular matrix composition is provided herein. The composition includes an extracellular matrix and at least one exogenous component selected from heparin,...
|
|
|
7604817 |
Method for promoting growth of tissue
A device and method for tissue engineering is disclosed. More particularly this invention relates to a bioabsorbable device and a method of its use which promotes controlled new tissue in-growth...
|
|
|
7597712 |
Method for treating a patient using a cultured connective tissue construct
The invention is directed to a method of tissue replacement and repair using a cultured bioremodelable connective tissue construct. The invention is specifically directed to a method for repairing...
|
|
|
7579189 |
Aligned scaffolds for improved myocardial regeneration
The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly...
|
|
|
7575926 |
Method of identification of compounds effective against suppressed cancer cells
A method for identifying compounds capable of targeting suppressed cancer cells, the method including the steps of comparing the response to a test compound of cancer cells grown on a suppressing...
|
|
|
7563608 |
Method for manufacturing a sintered compact for use as a cell culture base
A method for manufacturing a sintered compact having high density, and a sintered compact manufactured by the manufacturing method are provided. The manufacturing method comprises the steps of...
|
|
|
7556961 |
Method for collecting and acclimatizing anaerobic ammonuim oxidizing bacteria, and denitrifing water
A method for collecting bacterial cells comprising the steps of:
feeding water to be treated containing ammonium and nitrite to an anaerobic ammonium oxidation vessel to denitrify ammonium...
|
|
|
7553664 |
Three-dimensional skin model
The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an...
|
|
|
7544510 |
Stem cells of the islets of Langerhans and their use in treating diabetes mellitus
Methods and compositions are described for the treatment of type I insulin-dependent diabetes mellitus and other conditions using newly identified stem cells that are capable of differentiation...
|
|
|
7541187 |
Method of providing a substrate with a ready-to-use, uniformly distributed extracellular matrix
Method of providing a substrate with a ready-to-use uniformly distributed extracellular matrix is disclosed. This method includes applying extracellular matrix components to a substrate area;...
|
|
|
7537780 |
Method for preparing and implanting a cartilage construct to treat cartilage lesions
Neo-cartilage constructs for growth and surface coating for the de novo formation of a superficial cartilage layer. A method for generation of the neo-cartilage and the neo-cartilage construct. A...
|
|
|
7534610 |
3D tissue constructs on the basis of colloidal crystals surface modified by sequential layering
A cell growth matrix for optimizing 3D organization nutrient delivery, controlling release of differentiation factors and facilitating attachment of cells to a scaffold Colloidal crystals and...
|
|
|
7534609 |
Method of expanding undifferentiated hemopoietic stem cells
A method of expanding undifferentiated hemopoietic stem cells to increase the number of the hemopoietic stem cells is provided. The method comprising: (a) obtaining the undifferentiated hemopoietic...
|
|
|
7527803 |
PLGA substrate with aligned and nano-sized surface structures and associated method
A substrate for promoting growth of chondrocytes to repair articular cartilage is disclosed. The substrate comprises a polymeric material comprising aligned and nano-sized surface structures. An...
|
|
|
7521231 |
Method for preparing engineered tissue
A method for preparing a human or animal tissue by applying a compressive force to a stack of sheets of living tissue thereby inducing adjacent layers to fuse or adhere to each other. The force is...
|
|
|
7504258 |
Tissue engineered cellular sheets, methods of making and use thereof
The disclosure provides methods and composition to build living tissue covered stents and the like. These tissue coated stents provide a barrier against cell migration to the lumen of the vessel....
|
|
|
7479530 |
Polymer having charged units
A polymer comprising one or more macromonomer units selected from the group consisting of polysiloxane, perfluoroalkylpolyether (PFPE), fluorinated poly(meth)acrylate, polyalkyl (meth)acrylate,...
|
|
|
7468192 |
Method for repair of cartilage lesions
A method for treatment of injured, damaged, diseased or aged articular cartilage using neo-cartilage constructs implanted into a joint cartilage lesion in situ. The implantation of the construct...
|
|
|
7462471 |
Porous biodegradable polymeric materials for cell transplantation
Polymeric materials are used to make a pliable, non-toxic, injectable porous template for vascular ingrowth. The pore size, usually between approximately 100 and 300 microns, allows vascular and...
|
|
|
7449180 |
Macroscopic scaffold containing amphiphilic peptides encapsulating cells
The invention features peptide scaffolds that are useful in the repair and replacement of various tissues. The invention also provides methods for making these scaffolds and methods for using them.
|
|
|
7442546 |
Method of modulating inflammatory response
A method of immunomodulation by contacting the bodily fluid of a patient with renal tubule cells outside of the kidney.
|
|
|
RE40555 |
Preparation of agarose coated, solid agarose beads containing secretory cells
Biological agents such as secretory cells are encapsulated in a hydrophilic gel made of agarose or collagen-agarose and gelatin sponge-agarose combinations. In a preferred embodiment, semi-solid...
|
|
|
7440160 |
Electro-optical light modulating element, electro-optical display and modulating medium
The invention relates to electrooptical light modulating elements, to electrooptical displays containing elements of this type, and to display systems, e.g. television screens and computer...
|
|
|
7439057 |
Convective flow tissue assembly
The present invention provides for an improved in vitro tissue assembly system and related methods that includes and uses a bioreactor, a porous mandrel disposed in the bioreactor, and components...
|
|
|
7435594 |
Scaffold for culturing cells
A cell culture scaffold containing a gel having a network structure comprised of a synthetic polymer such that cultured cells spread in a shorter time and the number of adsorbed cultured cells per...
|
|
|
7422900 |
System and method for forming a connective tissue construct
A system and method are provided for forming a connective tissue construct, such as a tendon construct, in vitro. A substrate is provided with at least two anchors secured thereto in spaced...
|
|
|
7422879 |
Process for producing porous polymer films
Porous films are provided which include a blend of a film forming polymer and a non-film forming material, the film having a network of pores or channels throughout the film. The porous polymer...
|
|
|
7416887 |
Methods for use of MPL ligands with primitive human stem cells
Myeloproliferative leukemia receptor (mpl) ligands, such as thrombopoietin, act on a primitive subpopulation of human stem cells having the characteristics of self-renewal and ability to give rise...
|
|
|
7410791 |
Device containing cytophilic islands that adhere cells separated by cytophobic regions
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
|
|
|
7405078 |
Bed material for cell culture, method for co-culture of cell and co-cultured cell sheet obtainable therefrom
By using a bed material for cell culture having a surface composed of two domains of domain A coated with a temperature-responsive polymer and domain B composed of any one or a combination of a...
|
|
|
7402432 |
Process for producing T lymphocytes
The present invention is directed to an in vitro method for producing T lymphocytes. The method involves culturing bone marrow cells on a matrix seeded with keratinocytes and fibroblasts.
|
|
|
7399634 |
Method of preparing basement membrane, method of constructing basement membrane specimen, reconstituted artificial tissue using the basement membrane specimen and process for producing the same
The object of the present invention is to provide a method for preparing a basement membrane comprising extracellular matrices having a function to control morphology, differentiation,...
|
|
|
7393687 |
Biomimetic 3-dimensional scaffold with metabolic stream separation for bioartificial liver device
A bio-artificial organ comprises a substrate comprising a roll of a substrate material, and a plurality of cells adhered to the substrate, the roll being formed from a sheet rolled to form a...
|
|
|
7390652 |
Device for cultivating cells and propagating viruses
This invention relates to methods for the cultivating cells, and in particular to methods for propagating viruses.
|
|
|
7384786 |
Aligned scaffolds for improved myocardial regeneration
The present invention relates to a biocompatible, three-dimensional scaffold useful to grow cells and to regenerate or repair tissue in predetermined orientations. The scaffold is particularly...
|
|
|
7371400 |
Multilayer device for tissue engineering
The invention provides for translating two-dimensional microfabrication technology into the third dimension. Two-dimensional templates are fabricated using high-resolution molding processes. These...
|
|
|
7358089 |
Process for producing a substrate for attachment of cells
A process for production of a substrate for attachment of cells at certain positions and a substrate for attachment of cells. A support structure comprising a hydrophobic resin base material and a...
|
|
|
7354764 |
Method and device for culturing cells
In a method for culturing cells ( 2 ), according to which cells ( 2 ) are introduced into a cell culture chamber in order to form a cellular layer, the chamber being configured inside a carrier...
|
|
|
7354702 |
Processing tissue to produce a biopolymer scaffold for tissue engineering
A method of forming and preserving a bioremodelable, biopolymer scaffold material by subjecting animal tissue, particularly fetal or neo-natal tissue, to chemical and mechanical processing. The...
|
|
|
7341829 |
In situ growth, freezing and testing of cultured cells
The present invention provides methods and compositions for the in situ growth, freezing and testing of cultured cells. In particular, the present invention provides methods and compositions for...
|
|
|
7326571 |
Decellularized bone marrow extracellular matrix
The invention is directed to compositions comprising decellularized bone marrow extracellular matrix and uses thereof. Methods for repairing or regenerating defective, diseased, damaged or ischemic...
|
|
|
7326570 |
Induction of tubular morphogenesis using pleiotrophin
Provided are methods and compositions for constructing stable mammalian embryonic epithelial tissues and organs as well as constructing kidney tissue, and treating renal failure. Disclosed are...
|
|
|
7323190 |
Cell delivery system comprising a fibrous matrix and cells
Cell storage and delivery systems and methods for storing and delivering viable cells to a mammal are disclosed. The cell storage and delivery systems include a biodegradable and/or bioabsorbable...
|
|
|
7312065 |
Lawsonia intracellularis of European origin and vaccines, diagnostic agents and methods of use thereof
The present invention relates to Lawsonia intracellularis vaccines and methods for protecting against and diagnosing L. intracellularis infection. The products and processes of the invention...
|
|
|
7312046 |
Method of screening compounds using a nanoporous silicon support containing macrowells for cells
A nanoporous silicon support comprising a plurality of macropores is provided to function as a bioreactor for the maintenance of cells in culture in a differentiated state. Each cell or group of...
|
|
|
7297540 |
Methods of generating tissue using devitalized, acellular scaffold matrices derived from micro-organs
Methods of generating, and isolating adult stem cells and utilizing such cells and/or embryonic stem cells in generating tissue of a specific function and micro-architecture are provided.
|