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8173359 |
Methods and apparatus and assays of bacterial spores
A sample of unknown bacterial spores is added to a test strip. The sample of unknown bacterial spores is drawn to a first sample region on the test strip by capillary action. Species-specific...
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7957575 |
Counting biological agents on biological growth plates
The invention is directed to counting techniques for counting biological agents on a biological growth plate or similar medium. In order to automate the counting of biological agents, a biological...
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7838260 |
GFP-SNAP25 fluorescence release assay for botulinum toxin protease activity
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an...
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7824883 |
Method and apparatus for detecting the presence of microbes with frequency modulated multi-wavelength intrinsic fluorescence
Method and apparatus for the detection of microbes in liquids, in air and on non-living surfaces in which samples are exposed to frequency-modulated electromagnetic radiation of specific energies...
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7820444 |
Method for sample identification in a mammal as well as a kit for performing this method
Method as well a kit for the performance of the method for the investigation of biological samples from a mammal for at least one component, wherein the method includes the following steps: (a)...
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RE41887 |
Treatment of autoimmune disease
The present invention features a novel combination therapy useful in the treatment of autoimmune disease that increases or maintains the number of functional cells of a predetermined type in a...
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7803565 |
Use of lymphocytes to measure anthrax lethal toxin activity
It is disclosed herein that isolated lymphocytes, such as human B-cells and CD4+ T-cell can be used to determine an amount of lymphocyte-associated anthrax lethal toxin activity present. Methods of...
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7771660 |
Electrophoretic interactive spectral methods and devices for the detection and/or characterization of biological particles
Methods for identifying a biological particle in a sample medium include generating an Electrophoretic Quasi-elastic Light Scattering (EQELS) spectrum for the biological particle in the sample...
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7759128 |
Histamine detection method and histamine detection kit
The histamine detection method of the invention includes: a reaction step of causing a sample solution possibly containing histamine to react with 2,3-naphathalene dicarboxylaldehyde at PH of less...
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7746466 |
System and method for flow cytometry
A flow cytometry system and related method, among other things, are disclosed. In at least one embodiment, the system includes first, second, and intermediate slab formations, the last of which has...
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7738689 |
Counting biological agents on biological growth plates
The invention is directed to counting techniques for counting biological agents on a biological growth plate or similar medium. In order to automate the counting of biological agents, a biological...
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7718388 |
Universal biosensor and methods of use
The present invention relates to methods for detecting or quantifying an analyte in a test sample including providing at least one test mixture including a test sample, at least one marker complex,...
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7632686 |
High sensitivity quantitation of peptides by mass spectrometry
The instant invention provides an economical flow-through method for determining amount of target proteins in a sample. An antibody preparation (whether polyclonal or monoclonal, or any equivalent...
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7611862 |
Method and apparatus for detecting and quantifying bacterial spores on a surface
A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the...
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7585641 |
Immunoassay and method of use
A method for performing an immunoassay is described. The method is particularly useful for detecting extracellular polysaccharide (EPS) and/or lipopolysaccharide (LPS) producing microorganisms. The...
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7582415 |
Rapid detection of replicating cells
The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial...
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7582443 |
Method for the detection and measurement of Hapten-conjugated biological binding entities by western and dot-blot using anti-hapten antibodies
The invention is a procedure for measuring the binding of an entity (ligand) to a surface by using a hapten-conjugated version of the ligand (hapten-ligand). An excess of the hapten-ligand is...
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7569354 |
Cellomics system
In labeling a cell, and separating and collecting the cell according to a degree of the labeling using a cell separator, effects on the cell is minimized and the use of the collected cell is...
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7534584 |
Modular compositing-multiple lot screening protocols for detection of pathogens, microbial contaminants and/or constituents
Particular aspects provide a method of sampling, testing and validating test lots (e.g., single-unit production lots), comprising: assembling a plurality of product portions from each of a...
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7527979 |
Devices and methods for rapid detection of pathogens
Assay systems and methods are provided for detecting a target pathogen, such as a microorganism (e.g., bacterium, bacterial toxin) which may be present in a fluid or other location. The method can...
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7465560 |
System and method for rapid detection and characterization of bacterial colonies using forward light scattering
A system and a method of detecting and characterizing a bacterial colony are presented in which the results are determined within about 48 hours. The bacterial colony is disposed on a substrate and...
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7390489 |
Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
The present invention relates to a monoclonal antibody binding specifically to the p60 protein of Listeria monocytogenes, a hybridoma cell producing the monoclonal antibody, a test kit comprising...
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7374896 |
GFP-SNAP25 fluorescence release assay for botulinum neurotoxin protease activity
The present invention provides a nucleic acid molecule which contains a nucleotide sequence encoding a SNAP-25 substrate which includes (i) a green fluorescent protein; (ii) a first partner of an...
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7351798 |
Stabilized protein crystals, formulations comprising them and methods of making them
This invention relates to methods for the stabilization, storage and delivery of biologically active macromolecules, such as proteins, peptides and nucleic acids. In particular, this invention...
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7323328 |
Obligately symbiotic thermophile Symbiobacterium toebii SC-1 producing thermostable L-tyrosine phenol-lyase and L-tryptophan indole-lyase
The present invention relates to a novel obligately symbiotic thermophile Symbiobacterium toebii SC-1 (Accession NO: KCTC 0685BP), and a thermostable L-tyrosine phenol-lyase and L-tryptophan...
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7297551 |
Recombinant proteins and peptides for endotoxin biosensors, endotoxin removal, and anti-microbial and anti-endotoxin therapeutics
Recombinant fragments of Factor C are disclosed. These proteins and peptides show great potency in recognizing, binding to, neutralizing and removing endotoxin. These molecules can thus be used for...
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7132254 |
Method and apparatus for detecting phycocyanin-pigmented algae and bacteria from reflected light
The present invention relates to a method of detecting phycocyanin algae or bacteria in water from reflected light, and also includes devices for the measurement, calculation and transmission of...
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7112416 |
Detection of microbiological growth in a sealed container using a poising agent
According to the present invention, there is disclosed a method of stabilizing the output signal of a system that detects microbiological growth in a sealed sample container that contains a sample...
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7074586 |
Quantitative assay for low abundance molecules
A method for quantitatively assaying one or more target molecules in a sample uses a nucleic acid aptamer that is specific for each target molecule. A quantitative replicative procedure is used to...
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7052866 |
Method for evaluating the efficacy of an antifungal agent
A correct viable cell number of a microorganism in a biological tissue is measured by cultivating a fragment of the biological tissue such as skin infected with the microorganism and administered...
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7049093 |
Method of classifying and counting nucleated bone marrow cells
A method for classifying and counting nucleated bone marrow cells comprises the steps of: (1) mixing a sample of bone marrow fluid with an erythrocyte lysing agent to lyse erythrocytes in the...
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7018807 |
Method and medium for detecting vancomycin-resistant enterococcus
A microbe-specific medium for detection of vancomycin-resistant Enterococci in a test sample within 24 hours and preferably within 18 hours. The testing medium provides a selective growth medium...
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7015317 |
Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids
The present invention provides polynucleotides that can specifically hybridise to Hepatitis B virus (HBV) nucleic acids from all genotypes. These polynucleotides can be used in genotype-independent...
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6955886 |
Scintillation proximity assay for the detection of peptidoglycan synthesis
The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan...
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6942989 |
Methods, compositions and kits for biological indicator of sterilization
A novel biological indicator system to detect the effectiveness of a sterilization treatment and methods for assessing the viability of and/or changes in bacterial spores exposed to a sterilization...
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6929927 |
Method of evaluating antifungal agent
A correct viable cell number of a microorganism in a biological tissue is measured by cultivating a fragment of the biological tissue such as skin infected with the microorganism and administered...
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6916658 |
Method for measurement of immature granulocytes
A method for measuring immature granulocytes in a blood sample is described. The method includes the steps of lysing red blood cells of a blood sample with a lytic reagent, analyzing the sample...
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6903823 |
Method and device for the quantitative gas analysis
The invention relates to a device and a method for the quantitative gas analysis in which the gas analysis of a sample atmosphere is implemented by means of a sensor device, a diffusion seal being...
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6869798 |
Lytic reagent composition for leukocyte differential analysis
A lytic reagent composition and the method of use for differential analysis of leukocytes using flow cytometry are disclosed. The lytic reagent composition includes a short chain alkyl oxyethanol,...
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6838292 |
Detection of biological warfare agents
Methods and devices are provided for the detection of bacterial agents such agents as Bacillus anthracis and Clostridium botulinum with high sensitivity and selectivity. More specifically, methods...
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6833254 |
Method to identify IRES elements
A method to identify internal ribosome entry site (IRES) elements using a bicistronic expression system for reporter proteins is described. The IRES elements thus identified are useful in...
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6821744 |
Method, assay, and kit for quantifying HIV protease inhibitors
A method for quantifying an HIV protease inhibitor in a sample includes combining HIV protease, a conjugate comprising an HIV protease inhibitor analog, and a sample suspected of containing an HIV...
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6818417 |
Method for locating hidden microorganism contaminated surfaces in industrial water systems
A method for locating hidden microorganism contaminated surfaces in industrial water systems is described and claimed. The method works by applying a solution or dispersion of a fluorogenic reagent...
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6811971 |
Method for the detection of influenza A/B viruses
The invention concerns a method for the detection of an infection with influenza A and/or influenza B virus comprising the steps: i) obtaining a saliva sample, ii) preparing the saliva sample for a...
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6794156 |
Cell growth, induction and lysis in an antibody-coated microplate for use in an ELISA
A competitive assay to determine the presence and concentration of an intracellular analyte (e.g., cAMP) in a sample is provided. All of the steps of the assay can be performed on the same assay...
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6787333 |
Retrovirus isolated from humans
The present invention comprises spumavirus isolated from humans. More specifically, the spumavirus of the present invention was isolated from humans who had exposure to nonhuman primates....
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6783934 |
Methods for quantitative analysis of nucleic acid amplification reaction
A method for determining a threshold cycle number or time value in a nucleic acid amplification reaction comprising the steps of amplifying a nucleic acid sequence in a reaction mixture; at a...
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6764832 |
Plating media for the presumptive identification of the genus Shigella and the species Shigella sonnei and shigella boydii
A solid growth plating medium in which Shigella organisms will grow and form colonies in the medium, and substantially, other microorganisms are inhibited or their colonies are differentiated from...
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6716633 |
Blood cell detector, blood analyzer and blood analyzing method using the detector
A blood cell detector includes an orifice section having a single orifice, a first supplying section for supplying a first blood specimen into the orifice section, a second supplying section for...
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6686171 |
Competitive chemiluminescent assay for cyclic nucleotide monophosphates
A competitive assay for the concentration of a cyclic nucleotide such as cyclic adenosine monophosphate combines, in a reaction chamber provided with a capture antibody, an antibody for the cAMP or...
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