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7618622 |
Treatment of Parkinson's disease and related disorders using postpartum derived cells
Cells derived from postpartum tissue such as the umbilical cord and placenta, pharmaceutical compositions comprising such cells, and methods for using such cells and pharmaceutical compositions to...
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7595194 |
Isolation of mammalian CNS glial-restricted precursor cells
Multipotent neuroepithelial stem cells and lineage-restricted oligodendrocyte-astrocyte precursor cells are described. The neuroepithelial stem cells are capable of self-renewal and of...
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7553664 |
Three-dimensional skin model
The present invention relates to methods for cultivating dermal fibroblasts, methods for preparing in vitro dermis equivalents, methods for preparing three-dimensional in vitro skin equivalents, an...
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7524677 |
Mammalian cultured inner cell mass cell culture using a g1 cell as nuclear donor
A method of reconstituting an animal embryo involves transferring a diploid nucleus into an oocyte which is arrested in the metaphase of the second meiotic division. The oocyte is not activated at...
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7524489 |
Regeneration and repair of neural tissue using postpartum-derived cells
Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of neural tissue using the postpartum-derived...
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7514258 |
Mammalian cultured inner cell mass cell culture using a quiescent cell as nuclear
A method of reconstituting an animal embryo involves transferring the nucleus from a quiescent donor cell into a suitable recipient cell. The donor cell is quiescent, in that it is caused to exit...
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7510873 |
Postpartum cells isolated from umbilical cord tissue, and methods of making and using the same
Cells derived from human umbilical cords are disclosed along with methods for their therapeutic use. Isolation techniques, culture methods and detailed characterization of the cells with respect to...
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7473532 |
Liquid tissue preparation from histopathologically processed biological samples, tissues and cells
The current invention provides a method for directly converting histopathologically processed biological samples, tissues, and cells into a multi-use biomolecule lysate. This method allows for...
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7468277 |
Enriched preparation of human fetal multipotential neural stem cells
The present invention relates to a method of separating multipotential neural progenitor cells from a mixed population of cell types. This method includes selecting a promoter which functions...
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7456017 |
Processes for clonal growth of hepatic progenitor cells
A method of propagating mammalian endodermally derived progenitors such as hepatic progenitors, their progeny, or mixtures thereof is developed which includes culturing mammalian progenitors, their...
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7435586 |
Method of purification of cells
The present invention relates generally to a method for the generation of a substantially homogeneous population of undifferentiated cells. More particularly, the present invention relates to the...
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7413734 |
Treatment of retinitis pigmentosa with human umbilical cord cells
Cells derived from postpartum umbilicus and placenta are disclosed. Pharmaceutical compositions, devices and methods for the regeneration or repair of ocular tissue using the postpartum-derived...
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7399632 |
Mesenchymal precursor cell
A method of enriching mesenchymal precursor sells including the step of enriching for cells based on at least two markers. The markers may be either i) the presence of markers specific for...
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7393685 |
Method for cultivating cancer cells from human tissue and device for preparing tissue samples
The invention relates to a method for cultivating cancer cells for scientific serial assays, wherein a tissue sample which is heterogeneous with respect to contaminants, normal cells and tumor...
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7374937 |
Isolation and expansion of human marrow stromal cells
The invention includes in vitro methods of inducing and enhancing proliferation of human marrow stromal cells for use in, for example, gene therapy and transplantation methods. The invention also...
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7371576 |
CD56 positive human adult pancreatic endocrine progenitor cells
The invention relates to the discovery of a selective cell surface marker that permits the selection of a unique subset of pancreatic stems cells having a high propensity to differentiate into...
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7338757 |
Process for decellularizing soft-tissue engineered medical implants, and decellularized soft-tissue medical implants produced
The invention provides methodologies and apparatus for producing acellular soft-tissue implants, both in small quantities and in commercializable quantities. Such soft-tissue implants include...
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7335811 |
Method for collecting cells in M phase or G1 phase and method for nuclear transplantation using the cells
Methods for collecting cells in M phase or G 1 phase, by which the percentage of M phase or G 1 phase cells is higher than that attained by the conventional methods are disclosed.
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7318998 |
Tissue decellularization
The present invention relates, in general, to tissue decellularization and, in particular to a method of treating tissues, for example, heart valves, tendons and ligaments, so as to render them...
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7316926 |
Immortalized vascular adventital cell line
To provide an immortalized capillary pericyte line which maintains the original function/property of the cell line-deriving tissue, its establishment method, and the screening method for useful...
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7303912 |
Cultures of GFAP nestin cells that differentiate to neurons
Cultures of cells immunoreactive for glial fibrillary acidic protein (GFAP), as well as for the intermediate filament marker nestin were grown in a medium including epidermal growth factor (EGF)...
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7279330 |
Method for identifying modulating compounds of neurotransmitters
A process for identifying compounds that can modulate the release of neuromediators is described in which, for example, at least one compound that is to be tested is brought into contact with a...
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7273756 |
Method for chondrocyte expansion with phenotype retention
The present invention provides a method that maintains chondrocyte phenotype during serial expansion by culturing a population of chondrocytes in a defined serum-free culture medium containing...
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7264966 |
Method of isolating cell or sample to be analyzed in cell
There is disclosed a method of irradiating a specimen which is laid on a substrate and which includes a cell with a laser beam to remove an unnecessary specimen portion other than a cell portion...
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7252941 |
Expression profiling based on histocultures
Methods of obtaining faithful expression libraries from tissue samples comprise extraction of RNA from intact tissue cultured in three-dimensional sponge-gel based histocultures.
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7186554 |
Methods and compositions for human bladder epithelial cell culture
The present invention provides methods for culturing normal and malignant human bladder epithelial cells for many generations, and compositions of matter to be used in the methods.
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7109028 |
Methods of isolating hepatic progenitors
This invention relates to methods of isolating hepatoblasts utilizing panning techniques and fluorescence activated cell sorting. This invention further relates to isolated hepatoblasts and to a...
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7101710 |
Two-stage culture protocol for isolating mesenchymal stem cells from amniotic fluid
A method of harvesting mesenchymal stem cells from human amniotic fluid uses a two-stage culture protocol comprising culturing human amniocytes and then culturing mesenchymal stem cells. For...
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7094602 |
Method for cell culture
A method for detaching a carrier for cell culture from cultured cells formed on a surface of said carrier, which includes the step of bringing the carrier for cell culture into contact with a...
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7052907 |
Adult human dental pulp stem cells in vitro and in vivo
The present invention provides a culture of isolated adult human dental pulp stem cells that can differentiate into dentin/pulp tissue that can be used to produce a tooth in a human being. The...
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7045349 |
Method of islet isolation using process control
Advanced Islet Separation Technology incorporates an automated method, automated control methodology, process control interface, and automated apparatus to separate (isolate) and process pancreatic...
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7015036 |
Human liver cell line
In this application is described the establishment and maintanence of a normal human hepatocyte cell line able to support complete development of malaria parasite development in vitro. Advantages...
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6960473 |
In vitro mass production of human erythroid cells from the blood of normal donors and thalassemic patients
We describe a new two-step culture method for mass production in vitro of erythroid cells from either CD34 + (10 5 cells/mL) or light-density (10 6 cells/mL) cells purified from the blood of...
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6946293 |
Progenitor cells, methods and uses related thereto
The present invention relates to a substantially pure population of viable pancreatic progenitor cells, and methods for isolating such cells. The present invention further concerns certain...
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6900051 |
Process for obtaining mammalian insulin secreting cells in vitro and their uses
The present invention relates to a process for obtaining mammalian insulin secreting cells in vitro, characterized in that it contains the following steps: a) preparation of the mammalian...
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6872569 |
In vitro production of haploid germ cells
The present invention relates to a method of in vitro spermatogenesis involving Sertoli cells and diploid germ cells from a testis of a male mammal to yield differentiated haploid spermatids. The...
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6833270 |
Apparatus and method for isolating cells from organs
An apparatus and method for extracting cells from organs in which a digestion chamber includes at least one inlet and at least one outlet, and a separator for retaining the organ and permitting the...
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6830763 |
Continuous acidification demineralization process for producing osteoinductive bone; and osteoinductive bone produced thereby
The invention is directed to a process for producing demineralized osteoinductive bone, and demineralized osteoinductive bone produced thereby. The process achieves demineralization of bone by...
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6800442 |
Methods of selecting polynucleotides encoding antigens
The present invention relates to novel methods for the identification of antigens recognized by cytotoxic T cells (CTLs) and specific for human tumors, cancers, and infected cells, and the use of...
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6787355 |
Multipotent neural stem cells from peripheral tissues and uses thereof
This invention relates to multipotent neural stem cells, purified from the peripheral nervous system of mammals, capable of differentiating into neural and non-neural cell types. These stem cells...
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6783983 |
Methods for cultivating cells and propagating viruses
This invention relates to methods for the cultivating cells, and in particular to methods for propagating viruses.
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6767740 |
Stem cell and dental pulp harvesting method and apparatus
Methods and apparatus for recovering dental pulp from dentition of a donor are disclosed, wherein the pulp from within extracted teeth utilizing such methods and apparatus is harvested, while...
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6767738 |
Method of isolating adult mammalian CNS-derived progenitor stem cells using density gradient centrifugation
The present invention is directed to methods of repairing damaged or diseased, specialized or differentiated tissue in mature animals, particularly neuronal tissue such as retinas. In particular,...
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6753153 |
Markers for identification and isolation of pancreatic islet α and β progenitors
The differential expression of marker proteins in a targeted population provides a means of identifying and isolating cells. A population of cells associated with the regeneration of pancreatic...
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6680166 |
Dual fiber bioreactor
A cell culture unit is disclosed herewith comprising a shell having two ends with an elongated chamber there between. A liquid and a gas perfusion port are located on each end. Liquid perfusion...
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6664106 |
Production of primmorphs from disassociated cells of sponges and corals
This invention relates to the establishment of a novel method of culturing sponge cells, coral cells and cells from other invertebrates in vitro. The cells cultured in vitro, which can be cultured...
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6653089 |
Differential treatment of selected parts of a single cell with different fluid components
The present invention is directed, in certain embodiments, to improved, small scale systems and methods able to selectively treat parts of a single cell, including, in certain embodiments, portions...
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6585969 |
Non-viable keratinocyte cell composition or lysate for promoting wound healing
Cultures of keratinocyte cells are provided which are free from nonautologous fibroblasts and organ extracts, and which have a high speed of cell amplification for a minimum seeding density. The...
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6551589 |
Method of reducing the chance of attack of cells in a body by the cellular immune systems
A method of reducing the chance of disease resulting from mononuclear cells in a body attacking desirable cell antigens in the body, such as antigens expressed by normal body cells or desirable...
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6544751 |
Methods of harvesting rare cells from blood products
The present invention provides methods of harvesting rare cells from blood products and/or obtaining products of the rare cells. The method includes contacting a blood product containing rare cells...
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