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7071005 |
Method and device for concentrating selected groups of microorganisms
A method and device are described to concentrate target organisms from a mixture of organisms. Beads ( 1 ) made of material such as nylon, polystyrene or glass are coated with antibodies of...
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7067306 |
Device containing cytophilic islands that adhere cells separated by cytophobic regions
The invention provides a device for adhering cells in a specific and predetermined position, and associated methods. The device includes a plate defining a surface and a plurality of cytophilic...
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7063952 |
Masking background flourescence and luminescence in optical analysis of biomedical assays
In a process for the quantitative optical analysis of fluorescently labelled biological cells 5, a cell layer on a transparent support at the bottom 2 of a reaction vessel 1 is in contact...
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7052858 |
Diagnostic assays for detection of Cryptosporidium parvum
This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and...
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7033768 |
Reverse two-hybrid systems
Disclosed are methods for identifying molecular interactions (e.g., protein/protein, protein/DNA, protein/RNA, or RNA/RNA interactions). All of the methods within the invention employ...
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7026137 |
Hepatitis
A screening method of identifying a compound for treating hepatitis. Also disclosed is a method for evaluating responsiveness of a subject having hepatitis to a drug.
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7018807 |
Method and medium for detecting vancomycin-resistant enterococcus
A microbe-specific medium for detection of vancomycin-resistant Enterococci in a test sample within 24 hours and preferably within 18 hours. The testing medium provides a selective growth medium...
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7015317 |
Polynucleotides for the detection and quantification of hepatitis B virus nucleic acids
The present invention provides polynucleotides that can specifically hybridise to Hepatitis B virus (HBV) nucleic acids from all genotypes. These polynucleotides can be used in genotype-independent...
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7011957 |
Isolation and cultivation of microorganisms from natural environments and drug discovery based thereon
The method of the invention is directed to the novel use of a diffusion chamber within which previously “uncultivatible” microorganisms can be isolated. Rather than attempting to replicate the...
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RE39006 |
Method of detecting hematopoietic progenitor cells
Improved method for detecting and/or counting the appearance of hematopoietic progenitor cells which comprises the steps of mixing a blood sample with a reagent capable of detecting immature cells...
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7005257 |
Detection of antibiotic resistance in microorganisms
The invention relates to a process for detecting antibiotic resistances in microorganisms, in particular in bacteria, and to reagent kits which are suitable for implementing the process.
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6998250 |
Method for detecting Helicobacter pylori
A system and method for detecting bacterial infections in the gastrointestinal tract is disclosed. The system includes a carrier having a first well and a second well. A first composition is...
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6991918 |
Methods for improving sensitivity of oxygen biosensors
A method for detecting oxygen in a test sample is provided, the method involving exposing a test sample and a control sample to sensor compositions having a luminescent compound capable of...
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6991899 |
Cells for detection of influenza and parainfluenza viruses
The invention provides cell lines which are useful for the rapid detection and production of influenza and parainfluenza viruses. In particular, the invention relates to transgenic mink lung cells...
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6989246 |
Sensor formulation for simultaneously monitoring at least two components of a gas composition
The present invention is directed to a sensor system for monitoring metabolic activity of an anaerobic or aerobic microorganism. The present invention further relates to a sensor system that can...
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6984499 |
Method and apparatus for concurrently detecting pathogenic organisms and antimicrobial susceptibility
The present invention relates to a method of detecting the presence of target microorganisms in a biological sample and of simultaneously determining the susceptibility of the microorganisms to...
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6984500 |
Method for detecting microorganisms and detection kit
A method for detecting a microorganism by coloration is provided that includes adding and reacting, in a liquid culture medium, an alkaline sensitizing solution and a coloring reagent containing a...
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6984374 |
Method for the evaluation of implantable materials
A method for the evaluation of a material to determine whether the material is susceptible to bacterial contamination or colonization comprising providing bacteria which are modified to produce a...
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6969593 |
Method for the selective survival or selective growth of a target cell by the use of a conjugate, its use in therapeutics and/or diagnostics and the preparation of said conjugate
The invention is in particular related to a method for the selective survival or selective growth of a target cell comprising the steps of: a) contacting the target cell with a conjugate compound...
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6967086 |
Method for determining the presence or absence of respiring cells on a three-dimensional scaffold
The invention provides a method and apparatus for determining the presence or absence of respiring cells, involving combining a three-dimensional biomimetic scaffold and cells onto a sensor...
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6967084 |
Kit for rapidly diagnosing upper respiratory conditions
A kit for detecting upper respiratory conditions. The kit includes a container for collecting nasal secretions. The kit further comprises a means for providing a differential readout upon contact...
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6958221 |
Cell flow apparatus and method for real-time measurements of patient cellular responses
The present invention is directed to a method for determining the effect of each of a plurality of test agents on cells from a subject, and a method to profile patient cell responses to test agents.
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6955891 |
Reagents for assaying Bacillus anthracis lethal factor protease
The present invention features a Bacillus anthracis lethal factor substrate. The substrate can be used for example to measure lethal factor activity. Preferred substrates contain one or mare...
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6955886 |
Scintillation proximity assay for the detection of peptidoglycan synthesis
The invention provides a scintillation proximity assay for detecting peptidoglycan synthesis. The assay is especially suitable for high throughput screening of compounds affecting peptidoglycan...
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6951714 |
High-throughput microbial culturing
Methods for isolating microbial species, particularly previously uncultured species, from non-laboratory source environments (such as soil, freshwater, seawater, etc.) are disclosed. These methods...
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6951730 |
Method for rapidly diagnosing upper respiratory conditions
A method for detecting upper respiratory conditions. The method includes implementation of a device upon which are fixed discrete indicators of pH, protein content, nitrite content and/or leukocyte...
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6951733 |
Method for testing drug susceptibility of Mycobacterium tuberculosis
A novel agar medium for the isolation, sub-cultivation, and indirect or direct drug-susceptibility testing of Mycobacterium tuberculosis is disclosed. Also disclosed are methods of isolating and...
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6949355 |
Methods, compositions, and automated systems for separating rare cells from fluid samples
The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells from a complex fluid sample. In particular, the enrichment of fetal cells...
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6939687 |
Method of testing adequacy of cells in a specimen
The present invention provides a device and method for determining the adequacy of squamous (ectocervical) cells, columnar (endocervical) cells, neutrophils, and noncellular material in a liquid...
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6921635 |
Culture and identification media specific of different species of Candida and analysis methods
The invention concerns a culture and identification medium specific of yeasts comprising a chromogenous or fluorigenous substrate, capable of being hydrolyzed by an enzyme of the hexosaminidase and...
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6916658 |
Method for measurement of immature granulocytes
A method for measuring immature granulocytes in a blood sample is described. The method includes the steps of lysing red blood cells of a blood sample with a lytic reagent, analyzing the sample...
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6911338 |
Endophytic fungi and methods of use
This invention provides a novel endophytic fungus, Muscodor , that produces a mixture of volatile antibiotics with activity on specific plant pathogens, bacteria, nemotodes and insects. Also...
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6911312 |
Detection and characterization of microorganisms
A method for separating microorganisms, especially infectious agents, from a mixture by two dimensional centrifugation on the basis of sedimentation rate and isopycnic banding density, for...
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6908746 |
Rapid method of detection and enumeration of sulfide-producing bacteria in food products
A rapid method for detecting spoilage of a food sample, particularly a fish sample, by detecting and enumerating sulfide-producing bacteria (SPB). A growth medium containing iron and sulfur is...
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6908745 |
Gamma sterilizable culture medium for the identification of yeasts and fungi
Gamma sterilizable culture medium for the selectively identification of yeasts and fungi with an addition of ciprofloxacin and, if necessary streptomycin or other antibiotics.
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6905841 |
Enzymatic substrates for detecting Pseudomonas aeruginas
An enzyme substrate which includes a target portion and a marker portion, hydrolysis of the substrate leading to separation of the target portion from the marker portion, and the target portion...
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6902903 |
Helicobacter pylori diagnostics
Novel methods, membrane supports and immunodiagnostic test kits for diagnosing Helicobacter pylori infection, are disclosed. The methods can also be used to monitor the progress of treatment of...
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6900030 |
Device for monitoring cells
The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods...
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6900028 |
Reflective disc assay devices, systems and methods
Disc assay devices and methods for the detection and enumeration of microorganisms are disclosed. The devices and methods include a plurality of discs attached to a substrate and a reflector on one...
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6897037 |
Pre-treatment kit for saliva and pre-treatment method for saliva using the same
To provide a pre-treatment kit for saliva and a pre-treatment method for saliva for identification and quantitation of mutans streptococci in human saliva by the immunochromatographic method, which...
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6890762 |
Method for measuring physiocochemical properties of tissues of cells, method for examining chemicals, and apparatus therefor
A method of measuring the physical and chemical properties of tissue or cells and a device for the same is provided, with which the physical and chemical environment of the tissue or cells can be...
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6887681 |
Apparatus and methods for chemiluminescent assays
Disclosed is a device and methods for the rapid chemiluminescence assay of surfaces to detect the presence of microbial contamination. The device and methods are suitable for use by untrained...
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6884576 |
Methods of monitoring HIV drug resistance
A method is provided for detecting a presence of HIV virus in a sample comprising: taking a culture of recombinant cells which (a) are capable of cell division, (b) express CD4 receptor and one or...
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6872562 |
Herbicide resistant dinitrogen fixing bacteria and method of use
The present invention is directed to herbicide resistant N 2 fixing bacteria. The bacteria are useful for effecting N 2 fixation, nodulation, growth and yield of herbicide resistant or tolerant...
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6872291 |
Method and device for detecting and controlling the level of biological contaminants in a coating process
The presence of biological contaminants in a liquid coating composition is determined by measuring the carbon dioxide content of the atmosphere above the liquid and comparing the measured carbon...
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6872545 |
Microbiological analyzer using colorimetric means for biochemical color and growth determinations
A microbiological analyzer for performing ID tests on samples using colorimetric techniques to generate a pixel-wise colored map of a test region of interest and also performing MIC tests on...
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6855513 |
Quorum sensing signaling in bacteria
The invention provides methods for identifying a modulator of quorum sensing signaling in bacteria, and for identifying a quorum sensing controlled gene in bacteria. In addition, the invention...
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6855514 |
Method for detecting presence of microorganisms, and quantities of microorganisms
Fast microbial detection is accomplished without an indicator interfering with microorganism growth, without a culture medium degrading the performance of an indicator and without a color of test...
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6852504 |
Method for measuring cellular transmembrane potential changes
The invention encompasses an improved method for measuring membrane potential using compounds of the formula I as potentiometric probes. These probes may be used in combination with other...
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6849419 |
Monoclonal antibody hybridoma immunoassay method and diagnosis kit
The object of the present invention is to provide a diagnostic method by which Helicobacter pylori infection can be diagnosed at low cost without causing pain on subjects and without requiring...
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