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5688681 Monoclonal antibodies to human leukemia inhibitory factor  
The invention relates to monoclonal antibodies to human leukemia inhibitory factor. The disclosed monoclonal antibodies are believed to recognize unique epitopes on hLIF and are useful in the...
5677182 Cleavage site blocking antibody to prohormone proteins and uses thereof  
Cleavage site blocking antibody that binds to prohormones, preferable Tumor Necrosis Factor, thereby preventing the formation of prohormone fragment(s) by proteolysis of the prohormone, and uses of...
5656435 Antibodies to peptides having NGF-like activity, said antibodies having no substantial cross-reactivity with NGF, and use thereof  
Disclosed are (A) an antibody to a peptide including at least 8 successive amino acids of an amino acid sequence represented by formula TyrAlaGluHisLysSerHisArgGlyGluTyrSerValCys...
5654405 Antbodies to human kerctinocyte growth factor (KGF) and related pharmaceuticals  
Discoveries are disclosed that show particular aspects of recombinant DNA technology can be used successfully to produce hitherto unknown human keratinocyte growth factor (KGF) protein free of...
5627073 Hybridomas producing antibodies to cardiac hypertrophy factor  
Isolated CHF (also referred to cardiac hypertrophy factor or cardiotrophin-1), isolated DNA encoding CHF, hybridomas and cell lines producing antibodies to CHF, and recombinant or synthetic methods...
5614394 Method and monoclonal antibodies for vitamin B12 determination  
A method for making an monoclonal antibody specific for vitamin B12 by immunizing mice with vitamin B12-b-acid and isolating hybridomas that produce monoclonal antibodies which have an affinity...
5599708 Osteoclast growth regulating factors and antibodies  
The present invention relates to a novel osteoclast growth regulatory factor, hereinafter referred to as "osteoclastpoietic factor (OPF)," which stimulates the formation of osteoclast bone cells, a...
5580780 Vascular adhesion protein-(VAP-1) and VAP-1-specific antibodies  
A novel endothelial cell molecule, VAP-1, is described that mediates lymphocyte binding in man. Further described are anti-VAP-1 monoclonal antibodies and methods for the diagnosis and treatment of...
5571714 Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use  
Monoclonal antibodies have been produced which bind to Transforming Growth Factors β1 (TGF-β1) and β2 (TGF-β2). The monoclonal antibody produced by the hybridoma designated 1D11.16 deposited as...
5552286 Hybridoma cell lines and their monoclonal antibodies to human pluripotent granulocyte colony stimulating factor  
Murine-derived hybridoma tumor cell lines and monoclonal anti-human pluripotent Granulocyte Colony Stimulating Factor antibody substances produced by these cell lines. Use of said monoclonal...
5501988 Anti hCG-β core monoclonal antibody, its production and use  
A hybridoma capable of producing monoclonal antibody for recognizing hCG-β core region and hCG-β subunit, which is obtained by cell fusion of an antibody producing cell of a mammal immunized with...
5486472 Monoclonal antibodies to PACAP  
Disclosed are a monoclonal antibody having affinity for PACAP, a partial peptide thereof, a precursor thereof or VIP; a hybridoma cell which produces the above monoclonal antibody; and an...
5478740 Hybridomas and monoclonal antibodies which specifically bind human basic fibroblast growth factor  
A monoclonal antibody is produced from a cloned hybridoma, and the monoclonal antibody combines specifically with basic fibroblast growth factor (bFGF). Therefore, the monoclonal antibody can be...
5468846 Monoclonal antibodies and method for the determination of human G-CSF  
The present invention relates to a high affinity monoclonal antibody and to an enzyme immunoassay of human G-CSF using the antibody. The trace amount of human G-CSF in samples such as body fluids...
5468468 Method for making a monoclonal antibody, monoclonal antibodies to α P D  
Potent neutralizing monoclonal antibodies to the human α PDGF receptor (α PDGFR) and fragments thereof are described. These monoclonal antibodies specifically bind to an epitope on α PDGFR,...
5439795 Monoclonal antibodies that specifically bind somatotropin binding proteins but not to corresponding somatotropin receptors and methods of use in immunoassays  
The present invention is directed to antibodies, in particular monoclonal antibodies, which specifically bind to somatotropin binding proteins of animals, but not with the corresponding...
5437995 Monoclonal antibody against an acidic FGF protein and hybridoma for its production  
The present invention provides a hybrid cell line producing monoclonal antibody to an acidic fibroblast growth factor (aFGF) protein. The hybridoma is established by fusing spleen cells from...
5330909 Monoclonal antibody specifically recognizing N-terminal portion of human calcitonin  
A monoclonal antibody specifically recognizing N-terminal portion of human calcitonin (hCT), a hybridoma producing said monoclonal antibody, a process for preparing said monoclonal antibody, and a...
5290680 Monoclonal antibody, method of production thereof and use thereof  
The present invention relates to a monoclonal antibody which specifically recognizes 6,15-diketo-13,14-dihydro-prostaglandin F 1 α with high sensitivity, a hybridoma producing said monoclonal...
5266477 Monoclonal antibodies which differentiate between native and modified porcine somatotropins  
Monoclonal antibodies are provided which differentiate between native and modified sequence proteins. Also provided are methods for using monoclonal antibodies to determine the relative amount of...
5248593 Process and reagent for the determination of the luteinizing hormone and monoclonal antibodies suitable thereof  
The present invention provides an immunological process for the determination of the luteinizing hormone (LH), wherein at least one monoclonal antibody is used which is directed against LH and...
5230999 Monoclonal antibody to endothelin-3 or precursor thereof and use thereof  
Disclosed are monoclonal antibodies having an affinity for endothelin-3 or a precursor thereof; a hybridoma cell which produces the monoclonal antibody; and an immunoassay of endothelin-3 and big...
5217896 Monoclonal antibodies recognizing parathyroid hormone-like protein  
This invention provides a monoclonal antibody which specifically forms a complex with amino acids 1-87 of PTHLP which does not form a complex with amino acids 1-34 of PTHLP, and which forms a...
5109115 Monoclonal antibody specific for bombesin  
The present invention discloses anti-bombesin monoclonal antibody and a method of detecting autocrine growth factor. A method and kit for screening and controlling growth of human SCLC has also...
5094941 Monoclonal antibodies to PDGF  
Monoclonal antibodies (MAbs) capable of binding to native PDGF, and MAbs capable of specifically binding to the PDGF-AA, PDGF-BB and PDGF-AB isoforms are disclosed. The subject MAbs may be used in...
5084396 Enhanced production of antibodies utilizing insolubilized immune complexes  
A method for enhancing production of antibodies through immunization with insolubilized immune complexes is disclosed. Purified antigen or heterogeneous antigen mixtures may be combined with...
5070013 Immunochemical assay for human granulocyte-macrophage colony stimulating factor  
Monoclonal antibodies and compositions thereof are provided for detecting, measuring, and immunopurifying human GM-CSF.
5051364 Anti-lipocortin-I and anti-lipocortin-II monoclonal antibodies  
The present invention provides monoclonal antibodies which are specific for one but not both of human lipocortin-I and human lipocortin-II, as well as cultures of hybridomas and other types of...
4933275 Method for the detection of a polypeptide subunit in the presence of a quaternary protein containing the subunit  
A method for the determination of a free protein subunit of a quaternary protein in a sample, which comprises: (a) contacting a sample with a first immunological binding partner which is or will...
4888296 Monoclonal antibodies recognizing L-thyroxine  
Monoclonal antibodies specific for thyroxine (T 4 ) are produced by two new and separate hybridoma cell lines. Combinations of the monoclonal antibodies from the two cell lines are used in an...
4879112 Monoclonal antibodies agaisnt GnRH  
A monoclonal antibody against GnRH and particularly designated USASK/DSIL-GnRH is produced by a hybrid formed by fusion of cells from a myeloma line and antibody producing cells of the immune...
4859613 Immunoassays for glutathione and antibodies useful therein  
Monoclonal antibodies specifically immunologically reactive to thiol-modified glutathione and hybridoma cell lines producing such monoclonal antibodies. A method of producing antibodies...
4804626 Immunometric assay for the detection of human chorionic gonadotropin  
A highly sensitive and specific monoclonal-immuno-radiometric assay (M-IRMA) for hCG, using monoclonal antibodies (Mabs) directed against a 37-amino acid synthetic polypeptide analogous to the...
4762783 Process and reagent for the determination of the follicle-stimulating hormone and monoclonal antibodies suitable therefor  
The present invention provides an immunological process for the determination of the follicle-stimulating hormone (FSH), wherein there is used at least one monoclonal antibody which is directed...
4720455 Progesterone assay method for mammals and monoclonal antibody therefor  
A progesterone concentration level test for mammalian body fluids particularly adapted for milk whereby estrus and pregnancy can be determined. The test can be carried out with a kit of several...
4714681 Quadroma cells and trioma cells and methods for the production of same  
Antibodies having binding affinity for two desired antigens, hereinafter "recombinant monoclonal antibodies"; recombinant monoclonal antibodies produced by a quadroma cell or a trioma cell; and...
4565687 Monoclonal antibodies specific for the unbound β subunit of human chorionic gonadotropin  
Hybrid-myeloma cells which produce monoclonal antibody specific to the β subunit of human chorionic gonadotropin and methods of use of the monoclonal antibody.
4504586 Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1  
Murine-derived hybridoma tumor cell lines and monoclonal anti-Colony Stimulating Factor Subclass Number 1 antibody substances produced by these cell lines. Use of said monoclonal antibody...
4487833 Method of preparing hybridomas and of purifying immunogenic materials  
In a method for preparing a monoclonal hybridoma which secretes antibodies against an immunogenic material, comprising sensitizing an appropriate source with an immunizing amount of a preparation...
Matches 51 - 89 out of 89 < 1 2