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7390894 |
Glutathione S-transferase sequence variants
Isolated GSTO2 nucleic acid molecules that include a nucleotide sequence variant and nucleotides flanking the sequence variant are described, as well as GSTO2 allozymes. Methods for determining if...
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7390892 |
Nucleic acids encoding novel cyclic GMP dependent protein kinases from Elmeria maxima
The present invention relates to novel protozoal cyclic GMP dependent protein kinases and genes encoding same that have been isolated from Eimeria maxima and Plasmodium falciparum . Nucleic acid...
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7390891 |
Polynucleotides encoding a telomerase component TP2
Disclosed are nucleic acid molecules encoding polypeptides of the telomerase complex. Also disclosed are methods of preparing the nucleic acid molecules and polypeptides, and methods of using these...
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7390661 |
Artificial bidirectional promoter for activation of gene expression
A bidirectional module for activation of gene expression and regulation of transcription in both directions is disclosed. The bidirectional module comprises multiple cis regulatory DNA sequence...
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7390655 |
Promoter molecules for use in plants
The present invention provides DNA molecules isolated from corn and sorghum plants that are useful for expressing transgenes in plants. The present invention also provides expression constructs...
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7390654 |
Avoidance of undesirable replication intermediates in plasmid propagation
Disclosed herein are improved plasmid shuttle vectors, vaccines based on them, and methods related to their construction and use. Particular arrangements of functional elements of such plasmids,...
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7390643 |
Geranyl diphosphate synthase molecules, and nucleic acid molecules encoding same
In one aspect, the present invention provides isolated nucleic acid molecules that each encode a geranyl diphosphate synthase protein, wherein each isolated nucleic acid molecule hybridizes to a...
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7390642 |
Salutaridinol 7-O-acetyltransferase and derivatives thereof
This invention provides: (A) a protein the sequence of which is in FIG. 8 (SEQ. ID n° 14), or a fragment thereof having at least 15 amino acids, or a variant thereof, having at least 70%...
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7390640 |
Circular permutant GFP insertion folding reporters
Provided are methods of assaying and improving protein folding using circular permutants of fluorescent proteins, including circular permutants of GFP variants and combinations thereof. The...
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7390639 |
Staphylococcal nuclease fusion proteins for the production of recombinant peptides
Peptides are produced as fusions with a suitable carrier protein. The carrier protein disclosed herein are adapted from the N-terminal domain of staphylococcus nuclease. This novel carrier...
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7390638 |
S99T C-11 Truncated polynucleotides encoding interferon gamma polypeptide variants
When interferon gamma (IFNG) is produced in mammalian cell lines a heterogenous population of IFNG polypeptides is obtained due to C-terminal processing of the IFNG polypeptide. Clearly, this...
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7390636 |
Method for construction and use of Kluyveromyces lactis promoter variants in K. lactis that substantially lack E. coli transcriptional capability
Methods and compositions are provided relating to production of recombinant protein in yeast. A modified P LAC4 is described where one or more mutations may be introduced into the Pribnow box-like...
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7390632 |
Soluble ErbB3 receptor isoforms
The present invention discloses a system and method using the human ErbB3 receptor, p85-sErbB3, as a negative regulator of heregulin-stimulated ErbB2, ErbB3, and ErbB4 activation. The present...
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7388127 |
Multiple stress-inducible peroxidase promoter derived from Ipomoea batatas
The present invention relates to a multiple stress inducible promoter, more particularly to a multiple stress inducible peroxidase promoter derived by Ipomoea batatas , a expression vector for...
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7388125 |
Maize chloroplast protein synthesis elongation factors and methods of use for same
The invention discloses a novel heat shock protein with high homology to chloroplast elongation factor EF-Tu. Also disclosed is a transgenic method for enhancing tolerance to heat and drought in...
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7388091 |
Harvest-inducible genes from alfalfa (Medicago sativa) and methods of use thereof
The present invention relates to novel inducible genes from alfalfa. These genes are highly induced following mechanical harvesting or wounding of alfalfa. The genes are useful for inducible...
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7388086 |
NPHS2 gene involved in the steroid-resistant nephrotic syndrome, protein encoded by said gene and diagnostic and therapeutic uses
The invention concerns a novel gene, called NPHS2 gene coding for a protein involved in the cortico-resistant nephrotic syndrome, and diagnostic and therapeutic uses of the novel identified...
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7388084 |
Promoter motifs in Candida tropicalis
The present invention provides modified promoters from Candida troplicalis CYP and POX4 genes. The modified promoters have various sequence motifs added, deleted, or altered in order to modulate...
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7388077 |
Polypeptides having antimicrobial activity and polynucleotides encoding the same
The present invention relates to isolated polypeptides having antimicrobial activity and isolated polynucleotides encoding the polypeptides. The invention also relates to nucleic acid constructs,...
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7387896 |
MicroRNA vectors
The present invention relates to gene silencing, and in particular to compositions of microRNA sequences and vectors and to methods of synthesizing such in vitro and in vivo, and to methods of...
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7387894 |
Recombinant viral-based malaria vaccines
The present invention relates to novel vaccines against malaria infections, based on recombinant viral vectors, such as alpha viruses, adenoviruses or vaccinia viruses. The recombinant viral-based...
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7387893 |
Vectors, cells and processes for pyrimidine deoxyribonucleosides production
Novel DNA constructs and host cells comprising the same are disclosed. DNA constructs comprise a transcription unit (e.g. operon) comprising DNA sequences encoding for ribonucleotide reductase and...
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7387885 |
Growth factor homolog zvegf3 polynucleotides
Polypeptide growth factors, methods of making them, polynucleotides encoding them, antibodies to them, and methods of using them are disclosed. The polypeptides comprise an amino acid segment that...
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7385106 |
Plants tolerant of environmental stress conditions, methods of generating same and novel polynucleotide sequence utilized thereby
A method of generating a plant tolerant of environmental stress conditions, the method comprising the step of expressing within the plant exogenous polynucleotides encoding enzymes capable of...
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7385105 |
Root active promoters and uses thereof
The present invention is directed to root active promoter sequences, polynucleotide constructs comprising the root active promoters and methods of identifying the root active promoters, or...
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7385104 |
Plants synthesizing a modified starch, a process for the generation of the plants, their use, and the modified starch
The present invention relates to recombinant nucleic acid molecules which contain two or more nucleotide sequences which encode enzymes which participate in the starch metabolism, methods for...
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7385048 |
Promoters and utilization thereof
The present invention relates to improved promoters and utilization thereof, in particular to promoters which are improved so as not to undergo methylation in the course of constructing...
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7385045 |
Canine B7-1 nucleic acid molecules
The present invention relates to B7 proteins; to B7 nucleic acid molecules, including those that encode such B7 proteins; to antibodies raised against such B7 proteins; and to therapeutic compounds...
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7385044 |
Isolated peptides which bind to MHC Class II molecules, and uses thereof
Peptides which have an amino acid sequence identical to sequences found in tumor rejection antigen precursors, such as NY-ESO-1, and SSX-2, are disclosed. These peptides bind to MHC-Class II...
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7384923 |
Liposomes
Cationic liposomes with entrapped polynucleotide in the intravesicular space are described. The liposomes include cationic components such as cationic lipids such as DOTAP. Preferably the method of...
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7384913 |
PT32 sperm protein, sperm c-Yes, oocyte cytoplasmic c-Yes, and uses thereof
The perinuclear theca 32 (PT32) protein is disclosed and shown to interact with tyrosine kinase c-Yes. PT32, c-Yes, fragments thereof, and molecules that bind thereto can be used in methods of...
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7384784 |
Pax-encoding vector and use thereof
The present invention provides cells transformed with a nucleotide sequence encoding Pax7, Pax3 or both. The present invention also pertains to Pax-encoding vector that comprises a sequence...
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7384776 |
Expression vectors for increasing protein yield from a cell culture and methods of use thereof
Disclosed herein are compositions and methods for increasing protein production from a cell culture. By switching the cells from a replicative to a productive state (RP switch), protein...
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7384775 |
Streptococcus pneumoniae open reading frames encoding polypeptide antigens and uses thereof
The present invention relates to newly identified open reading frames comprised within the genomic nucleotide sequence of Streptococcus pneumoniae , wherein the open reading frames encode...
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7384767 |
Nucleic acid encoding an interleukin-9 receptor variant
This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One...
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7384735 |
Retinoblastoma nucleic acids
This invention relates to nucleic acid, or fragments thereof, encoding the retinoblastoma polypeptide, the retinoblastoma polypeptide itself, methods of detecting a defective retinoblastoma gene in...
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7381813 |
Nucleic acids encoding estrogen receptor ligand binding domain variants
Mutants of steroid receptor ligand binding domains and synthetic ligands which have specific binding affinities for these receptors are provided. The use of these LBD-ligand combinations for...
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7381711 |
Substances for preventing and treating autoimmune diseases
A substance for preventing, delaying the onset of, or treating one or more than one autoimmune disease, the substance comprising a polynucleotide construct comprising a polynucleotide sequence...
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7381554 |
UDP-N-acetylglucosamine: galactose-β1,3-N-acetylgalactosamine-α-R/N-acetylglucosamine-β1,3-N-acetylgalactosamine-α-R (GlcNAc to GalNAc) β1,6-N-acetylglucosaminyltransferase, C2/4GnT
A novel gene defining a novel human UDP-GlcNAc: Gal/Gl cNAcβ 1-3GalNAc αβ1, 6GlcNAc-transferase, termed C2/4GnT, with unique enzymatic properties is disclosed. The enzymatic activity of C2/4GnT...
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7381544 |
Nucleic acid that encodes a fusion protein
This invention provides fusion polypeptides that include a glycosyltransferase catalytic domain and a catalytic domain from an accessory enzyme that is involved in making a substrate for a...
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7381543 |
TAB1 protein and DNA coding therefore
TAB1 protein having activity which activates factor TAK1 in the TGF-β signaling pathway, and having the amino acid sequence shown in FIG. 1.
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7381542 |
Nucleic acids encoding a biogenic amine receptor
The present invention relates to novel mammalian biogenic amine receptor proteins and genes that encode such proteins. The invention is directed toward the isolation and characterization of...
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7381405 |
Methods of preparing lymphocytes that express interleukin-2 and their use in the treatment of cancer
The invention provides methods of preparing autologous T-lymphocytes for re-introduction into a patient having cancer, which method comprises obtaining peripheral blood mononuclear cells (PBMCs)...
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7378573 |
Snow1: interacts with Ice1 and regulates CBF expression and freezing tolerance in Arabidopsis
The present invention relates to a protein (Snow1), mutants thereof, and nucleic acids encoding said protein, that interacts with Ice1 and which activates CBF3 promoter activity thus regulating...
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7378572 |
Constitutive expression cassettes for regulation of plant expression
The present invention relates to expression cassettes comprising transcription regulating sequences with constitutive expression profiles in plants obtainable from Arabidopsis thaliana genes...
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7378571 |
Promoter, promoter control elements, and combinations, and uses thereof
The present invention is directed to promoter sequences and promoter control elements, polynucleotide constructs comprising the promoters and control elements, and methods of identifying the...
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7378512 |
Production of proteins by autoproteolytic cleavage
The present invention relates to a process for the production of a heterologous polypeptide with homogeneous N-terminus in a bacterial host cell, wherein the heterologous polypeptide is...
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7378510 |
Synthetic zinc finger protein encoding sequences and methods of producing the same
The invention relates to nucleic acids encoding synthetic zinc finger proteins for gene regulation in plants. The invention also relates to methods of producing synthetic zinc finger protein in...
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7378506 |
Synthetic genes for plant gums and other hydroxyproline-rich glycoproteins
A new approach in the field of plant gums is described which presents a new solution to the production of hydroxyproline(Hyp)-rich glycoproteins (HRGPs), repetitive proline-rich proteins (RPRPs)...
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7378278 |
Enzymes involved in triterpene synthesis
This invention relates to isolated polynucleotides encoding a CYP51H. The invention also relates to the construction of recombinant DNA constructs comprising all or a portion of the isolated...
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