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7626009 |
PUFA polyketide synthase systems and uses thereof
Disclosed are the complete polyunsaturated fatty acid (PUFA) polyketide synthase (PKS) systems from the bacterial microorganisms Shewanella japonica and Shewanella olleyana , and biologically...
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7622631 |
Methods for enhancing plant resistance to pathogens
The present invention relates to methods of producing transgenic plants having resistance to blast fungus and/or leaf-blight bacteria by transforming the plants with a DNA encoding a protein that...
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7622300 |
Trans-lentiviral vector particles and transduction of eukaryotic cells therewith
Trans-lentiviral gene transfer vectors, vector systems, vector particles, and methods for transduction of primary nondividing cells using the same, are described. Further described are...
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7622282 |
Biosynthesis of isopentenyl pyrophosphate
Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a...
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7622297 |
Pharmaceutical use of α antigen or α antigen gene
The α antigen-encoding gene and the α antigen protein suppress the production of interleukin-4 etc., improve the Th2 type cytokine-dominant state, and furthermore inhibit various conditions of...
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7622570 |
Plants expressing putative palmitoyl protein thioesterase
Isolated nucleic acids and proteins associated with lipid and sugar metabolism regulation are provided. In particular, putative palmitoyl protein thioesterase and encoding nucleic acids are...
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7622291 |
Agarase and gene thereof
Production of efficiently producing agaro-oligosaccharide; a polypeptide having an agarase activity which is usable in, for example, efficiently extracting a substance such as a nucleic acid from...
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7622292 |
Regulation of human transmembrane serine protease
Reagents that regulate human transmembrane serine protease activity and reagents that bind to human transmembrane serine protease gene products can be used to regulate extracellular matrix...
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7622287 |
Myceliophthora thermophila laccase variants
The present invention relates to a method of designing laccase mutants with increased oxidation potential and/or changed pH optimum and/or altered mediator pathway and/or altered O 2 /OH −...
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7622288 |
Sesquiterpene synthases from patchouli
The invention relates to sesquiterpene synthases from Patchouli plants ( Pogostemon cablin ), and methods of their production and use. In one embodiment, the invention provides nucleic acids...
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7622637 |
Seed-preferred regulatory elements
The present invention provides compositions and methods for regulating expression of nucleotide sequences in a plant. Compositions are novel nucleotide sequences for a tissue preferred promoter...
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7622278 |
Compositions and methods for diagnosing or treating psoriasis
In one aspect, the present invention provides isolated nucleic acid molecules that encode a CAN-1 polypeptide, or an STG polypeptide. In another aspect, the present invention also provides isolated...
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7622284 |
Transformed eukaryotic cells that directly convert xylose to xylulose
The present invention relates to host cells transformed with a nucleic acid sequence encoding a eukaryotic xylose isomerase obtainable from an anaerobic fungus. When expressed, the sequence...
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7622283 |
Methods for synthesizing mevalonate
Methods for synthesizing isopentenyl pyrophosphate are provided. A first method comprises introducing into a host microorganism a plurality of heterologous nucleic acid sequences, each coding for a...
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7622658 |
Compositions and methods for altering tocotrienol content
The invention provides isolated nucleic acids and their encoded polypeptides that alter tocotrienol content in seeds. The invention further provides expression cassettes, host cells and transformed...
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7622565 |
Nucleic acids encoding B7-H4, a T cell immunoregulatory molecule
The invention provides novel B7-H3 and B7-H4 polypeptides useful for co-stimulating T cells, isolated nucleic acid molecules encoding them, vectors containing the nucleic acid molecules, and cells...
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7622109 |
Plant gene and uses thereof
A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as use for the enzyme in...
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7622127 |
Clostridial toxin derivatives and methods for treating pain
Agents for treating pain, methods for producing the agents and methods for treating pain by administration to a patient of a therapeutically effective amount of the agent. The agent can include a ...
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7622303 |
Methods for identifying patients at risk for life threatening arrhythmias
In general, the invention is directed to systems and techniques for assessing a risk of ventricular tachyarrhythmia in a patient by measuring one or more biochemical markers that reflect the health...
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7622290 |
Fungal lipolytic enzymes, nucleic acids encoding, and uses thereof
A fungal wild-type lipolytic enzyme having a higher ratio of activity on polar lipids compared with triglycerides, wherein the enzyme preferably has a phospholipid:triglyceride activity ratio of at...
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7618623 |
Hybrid adeno-retroviral vector for the transfection of cells
An adenovirus, including adenoviral capsid proteins, and a replication-defective adenoviral vector that includes a 5′ retroviral LTR nucleic acid sequence, a 3′ retroviral LTR nucleic acid...
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7618814 |
Microrna-related nucleic acids and uses thereof
The present invention relates to a first group of novel genes, here identified as genomic address messenger or GAM genes, and a second group of novel operon-like genes, here identified as genomic...
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7618943 |
Fusion polypeptides, and use thereof in antivascular tumor therapy
The present invention relates to fusion polypeptides, comprising at least two peptides. The invention further relates to the use of these fusion proteins in antivascular therapy of neoplastic...
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7618802 |
Compositions of coronaviruses with a recombination-resistant genome
The present invention provides a cDNA of a severe acute respiratory syndrome (SARS) coronavirus, recombinant SARS coronavirus vectors, and SARS coronavirus replicon particles. Also provided are...
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7618799 |
Bacterial leader sequences for increased expression
Compositions and methods for improving expression and/or secretion of protein or polypeptide of interest in a host cell are provided. Compositions comprising a coding sequence for a bacterial...
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7618795 |
Starch process
The present invention relates to a process for enzymatic hydrolysis of granular starch into a soluble starch hydrolysate at a temperature below the initial gelatinization temperature of said...
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7619134 |
Starches produced by the expression of heterologous granule bound starch synthase genes
The present invention is directed to an isolated starch, a transgenic plant or plant part producing the starch, flour and a thickened foodstuff prepared from a grain capable of producing such...
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7619077 |
Nucleic acids encoding a galacturonosyl tranferase enzyme (GALAT1) from arabidopsis
The invention provides an isolated nucleic acid molecule encoding the polypeptide GALAT1 having galacturonosyltransferase (GalAT) activity. The Arabidopsis GALAT1 sequence disclosed represents...
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7619065 |
Cystine-knot fold protein
This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this...
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7618816 |
Metal-binding therapeutic peptides
The present invention is related methods of delivering MBD peptide-linked agents into live cells. The methods described herein comprise contacting MBD peptide-linked agents to live cells under a...
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7619135 |
Seed-specific promoter from the rice glutelin GluB-4 gene and uses thereof
An objective of the present invention is to provide promoters having seed-specific promoter activity, and methods of expressing foreign proteins in seeds. In particular, a seed specific promoter...
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7619078 |
Nucleic acid molecules encoding B7-1
Novel structural forms of T cell costimulatory molecules are described. These structural forms comprise a novel structural domain or have a structural domain deleted or added. The structural forms...
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7619138 |
Precise breeding
The present invention relates to a new plant breeding process. The process improves the agronomic performance of crop plants by using genetic material that is also used in classical breeding....
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7618815 |
Viral vectors useful in soybean and methods of use
The invention provides Bean pod mottle virus (BPMV) vectors useful for expression of heterologous proteins in plants such as soybean. The BPMV vectors are also useful for virus-induced gene...
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7618775 |
Expanding the eukaryotic genetic code
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include...
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7615626 |
Methods, agents, and compound screening assays for inducing differentiation of undifferentiatied mammalian cells into osteoblasts
The present invention relates to methods, agents and compound screening assays for inducing differentiation of undifferentiated mammalian cells into osteoblasts. The invention thus provides a...
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7615360 |
Use of Saccharomyces cerevisiae erg4 mutants for expressing mammalian glucose transporter
The invention relates to yeast strains in which a human GLUT4 transport or a human GLUT1 transporter can be functionally expressed and to particular GLUT4 transport proteins which can be...
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7615679 |
Method of producing polyunsaturated fatty acids, novel biosynthesis genes, and novel plant expression constructs
The present invention relates to a method for the production of unsaturated fatty acids with at least two double bonds. The invention further relates to the use of the nucleic acid sequence of SEQ...
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7615681 |
Methods for modifying plant responses to stress and correspondingly derived plants
Plant stresses such as pest drought, and excessive temperatures can lead to significant losses of crops each year. There is a continuing need to develop novel plant varieties that are less...
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7615678 |
Methods for using artificial polynucleotides and compositions thereof to reduce transgene silencing
The materials and methods disclosed provide for polynucleotide molecules sufficiently divergent from polynucleotides naturally contained in plants, or polynucleotides previously introduced into...
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7615537 |
Methods for treating blood coagulation disorders
The present invention relates to a method of treating an individual having a blood coagulation defect (e.g., hemophilia A, hemophilia B), comprising administering to the individual an effective...
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7615362 |
Isolated xylanase gene with mutations and site-specific mutagenesis method thereof
A mutated xylanase gene with a broad pH range of reaction includes a forty-first amino acid or a twenty-first amino acid generated from transforming asparagine to aspartic acid so as to form the...
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7615680 |
Temporal seed promoters for expressing genes in plants
The present invention relates to the field of plant genetic engineering. More specifically, the present invention relates to seed specific gene expression during a defined period of embryogenesis....
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7615365 |
α(1,6)-linked glucose oligosaccharide hydrolyzing enzyme polynucleotides and polypeptides and methods of use thereof
This invention relates to a method for utilizing less purified starch in fermentation processes. One example is a recombinant E. coli containing a exogenous extracellular isoamylase activity that...
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7615215 |
Anti-human VEGF receptor Flt-1 monoclonal antibody
The present invention provides an antibody or peptide which immunologically reacts with human VEGF receptor Flt-1 and cells in which human VEGF receptor Flt-1 is expressed on the cell surface and...
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7615686 |
Expression and use of novel pesticidal toxins
A novel pesticidal toxin isolated from Bacillus thuringiensis that is highly active against a wide range of lepidopteran insect pests is disclosed. The DNA encoding the pesticidal toxin can be...
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7615364 |
Polypeptide having activity of unsaturating W3-fatty acid, polynucleotide coding for the polypeptide and use thereof
The present invention provides a polypeptide having a wide substrate specificity and having a ω3 fatty acid desaturation activity, which makes efficiently unsaturated bond at ω3 position, and a...
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7611865 |
Polynucleotides encoding truncated glial cell line-derived neurotrophic factor
Disclosed are novel proteins, referred to as truncated glial cell line-derived neurotrophic factor (truncated GDNF) proteins, that promote dopamine uptake by dopaminergic cells and promote the...
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7612046 |
Method for treating kidney disorders
The present invention relates to a cellular therapy of renal failure, i.e. preventing, delaying, and treating acute/chronic renal failure via the use of an effective dose of a substance capable of...
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7611868 |
Recombinant modified adenovirus fiber protein
Recombinant adenoviruses comprising modified fiber proteins which expand the tropism of the adenovirus in comparison to wild-type virus are disclosed. The modified fiber proteins described herein...
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