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8986946 Real-time method for the detection of viable micro-organisms  
The invention relates to a method for real-time detection of viable microorganisms comprising: a. addition of a cell-permeable, phototautomeric compound to a micro-organism or other living cell;...
8962550 Identification of inhibitors of a bacterial stress response  
A system, a composition, a method and a kit for identifying anti-bacterial agents are provided. The invention described herein is useful in identifying inhibitors of any bacterial stress response....
8951748 Rapid detection of molds that produce glucose oxidase  
Methods and kits are disclosed for detecting microorganisms that produce glucose oxidase. The method includes providing a culture medium and a hydrogen peroxide indicating reagent comprising a...
8945847 Methods and kits for ascertaining biosafety of an agent  
A method of ascertaining the bio-safety of an agent is disclosed. The method comprises: (a) contacting the agent with differentiating human pluripotent stem cells;(b) analyzing a level of gene...
8940183 Method of making a nano-particle photocatalyst  
A novel composition for a photocatalyst Fe doped ZnO nano-particle photocatalyst that enables the decontamination process by degrading toxic organic material such as brilliant cresyl blue, indigo...
8906602 Methods for identifying candidate compounds for treating, reducing, or preventing pathogenic infections  
Disclosed are methods for identifying candidate compounds for treating, reducing, or preventing a pathogenic infection, the methods including: (a) contacting a pathogenic cell with a candidate...
8906643 Method for screening drug candidates by using domain protein  
The present invention relates to a method for screening and discovering bioactive materials using specifically selected protein domains interacting with specific intracellular proteins, and more...
8895260 Screening assay for ribosomal antibiotics  
The present invention is directed to a method for identifying ribosomal antimicrobial substances being selective for microbial but not for mitochondrial and/or cytosolic ribosomes. Specifically,...
8871438 Disease diagnosis method, marker screening method and marker using TOF-SIMS  
The present invention relates to a disease diagnosis method, a marker screening method, and a marker using a time-of-flight secondary ion mass spectrometry (TOF-SIMS), and more particularly, to a...
8865427 Perifusion device  
A perifusion device includes at least one sample container for cells, the sample container having an inlet and an outlet. The container receives test liquid through the inlet and discharges the...
8828680 Combined rapid susceptibility assay and microorganism identification system  
In response to the need for highly-sensitive antibiotic susceptibility assays and identification assays that do not require extensive incubation times, the present invention provides automated...
8815535 Disk diffusion assay for oritavancin  
The present invention is directed to a disk diffusion assay for determining susceptibility of bacteria to a glycopeptide antibiotic. The assay includes improvements over conventional assays due to...
8785141 Bacterial toxin adsorbing material, method of removing the toxin by adsorbing, and an adsorber formed by filling the adsorbing material therein  
The invention aims at providing an adsorbent for bacterial toxins, a method for removal of such toxins by adsorption, and an adsorber packed with said adsorbent. Provided are an adsorbent for...
8785149 In vitro cellular bioassay for neurotoxicity testing  
The present invention provides neurotoxicity and developmental neurotoxicity screening methods employing primary cultured neurons from Drosophila.
8784795 Methods for determining personalized treatment compositions for prostate cancer and breast cancer  
The present disclosure provides methods for selecting a treatment composition, or therapy, for the treatment of a cancer, such as prostate or breast cancer, in a patient wherein the treatment...
8785148 Method and device for rapid detection of bacterial antibiotic resistance/susceptibility  
Described herein is a method and a device for expediting delivery of an agent to a damaged bacterial cell. In one embodiment, the methods and devices are useful for screening candidate...
8765393 Endotoxin-binding ligands and their use  
An affinity ligand-matrix conjugate of the structure Z-Spacer-[NX-A]m-NY-A-NK2 is useful for the isolation, separation, purification, characterization, identification or quantification of...
8759076 Method and apparatus for detecting an electric field fluctuation associated with the permeabilization of a bacterial cell wall  
A sensor for detecting an electric field fluctuation associated with the permeabilization of a bacterial cell wall comprises a substrate, at least two electrodes integrated on the substrate, an...
8748572 RNase a peptides, fragments and uses thereof  
The present invention features isolated polypeptides that have bactericidal and angiogenic activities. The invention features isolated polypeptides comprising amino acid sequences of RNase A...
8748087 Sequence of reverse transcriptase gene and method of use  
The present invention provides an isolated polynucleotide acid comprising a polynucleotide sequence having a substantial amount of sequence identity to the entire length of the polynucleotide...
8734785 Compositions to inhibit pathogenic growth  
The invention includes compositions for treating an animal to inhibit the incidence and growth of E. coli O157:H7 and other pathogenic bacteria. The composition is a therapeutically effective...
8728743 Microorganisms having intestinal cell surface glycosylation modulating action  
The invention concerns micro-organism strains, in particular of lactic acid bacteria, having a glycosylation modulating effect of intestinal cell surface. The invention also concerns a method for...
8715697 Genes associated with Leishmania parasite virulence  
The invention relates to the field of combating leishmaniases. Said invention results from the isolation, from wild isolates of Leishmania major, of a protein-coding gene known as LmPDI which has...
8709262 Synthesizing and utilizing solar light activated nano-particle photocatalyst  
Toxic organic materials contaminate water resources and one need to find an easy and energy efficient way to decontaminate water resources. The current invention discloses a photocatalyst Fe doped...
8685638 Cellular microarrays for screening differentiation factors  
Provided is a microarray platform for the culture of cells atop combinatorial matrix mixtures; enabling the study of differentiation in response to a multitude of microenvironments in parallel.
8674172 Prostate cancer cell lines and their use in screening method  
The present invention relates to a prostate cancer cell line CNCM deposit number I-4126, the use thereof for preparing resistant prostate cancer cell lines, the resistant prostate cancer cell...
8609364 Methods for antimicrobial resistance determination  
The present invention relates to methods and systems for determining the antibiotic-resistance status of microorganisms. The invention further provides methods for determining the...
8603739 Inhibitors of Rv0256c  
Described herein are methods for identifying inhibitors of Rv0256c functions, e.g., inhibitors of Rv0256c expression, DNA binding, nuclear localization and iNOS inhibition.
8592162 Compositions, methods and kits for repressing virulence in gram positive bacteria  
Bacterial virulence is repressed by compositions and methods for activating permanently a repressor of virulence factors. Compositions provided contain at least one non-metabolizable analog of...
8551499 In vitro model of latent mycobacterial infection  
A method of inducing latency in Mycobacterium permits preparation of an in vitro model system of latent mycobacterial infection. Latency is induced in a pure culture of Mycobacterium by exposing...
8541197 Targets, including Yap1, for antifungal drug discovery and therapy  
The present invention is based on the discovery of a two organism model system that can be used to identify virulence factors. The system is also useful in the process of drug delivery. More...
8518712 Method for discovering pharmacologically active substance of natural products using high resolution mass spectrometry and pharmacological activity test  
A method for discovering pharmacologically active substances from natural products at high speed, including: obtaining an activity profile by testing pharmacological activity of a plurality of...
8481280 Method for determining activity of an antibiotic with hops  
A method for determining the combined activity of two or more ingredients by impregnating a carrier with one ingredient and bringing it into contact with target material to create a zone of...
8481281 Systems and methods for determining drug resistance in microorganisms  
The present invention is based on the discovery that drug resistance in microorganisms can be rapidly and accurately determined using mass spectrometry. A mass spectrum of an intact microorganism...
8476064 Inhibition assay method and device for detection of antibiotics  
An aspect of the disclosure is a method and device for the detection of antibiotics in a sample. Embodiments include a microbial culture with growth indicators and sensitivity adjustment reagents....
8455214 Methods for determining chemotherapeutic agents targeting alpha-glucan pathways and uses thereof  
The present invention provides methods for determining a putative antibacterial, the methods comprising determining whether the putative antibacterial inhibits GlgE or Rv3032. The present...
8416405 Raman chemical imaging of implantable drug delivery devices  
A system and method of determining an attribute of a biological tissue sample or a drug delivery device. A sample is illuminated with substantially monochromatic light to thereby generate Raman...
8389233 Modular compositing-multiple lot screening protocols for detection of pathogens, microbial contaminants and/or constituents  
Provided are methods for sampling, testing and validating test lots, comprising: assembling a plurality of product portions from each of a plurality of test lots and combining the portions to...
8389234 Kits for the detection of beta-lactamases  
Presented herein are kits for the detection of specific beta-lactamases, including class A serine carbapenemases, metallo-beta-lactamases, AmpC beta-lactamases, and extended-spectrum...
8354371 Cadherin receptor peptide for potentiating Bt biopesticides  
Disclosed is a novel cadherin peptide that enhances the toxicity of Cry proteins. A novel insecticide composition comprising an effective amount of cadherin peptide having SEQ. ID. NO:2 and an...
8338114 Engineered human broncho-epithelial tissue-like assemblies  
Three-dimensional human broncho-epithelial tissue-like assemblies (TLAs) are produced in a rotating wall vessel (RWV) with microcarriers by coculturing mesenchymal bronchial-tracheal cells (BTC)...
8318452 Solid culture medium for the detection and/or the species discrimination of glycopeptide-resistant enterococci  
The present invention relates to a solid culture medium for the detection and/or discrimination, among glycopeptide-resistant enterococci, of the groups of species E. faecalis and/or E. faecium...
8309322 Diterpene modulator of macrophage phagosomal maturation  
Novel uses for diterpene modulators of macrophage phagosomal maturation are provided. The diterpene isotuberculosinol is used as an immune modulator, assay for pharmaceutical compositions and an...
8293496 Mass spectrometric measurement of microbial resistances  
Microorganisms, particularly bacteria, are identified and characterized on the basis of a mass spectrometric measurement of their protein profiles with ionization by matrix-assisted laser...
8283117 Disease diagnosis method, marker screening method and marker using TOF-SIMS  
The present invention relates to a disease diagnosis method, a marker screening method, and a marker using a time-of-flight secondary ion mass spectrometry (TOF-SIMS), and more particularly, to a...
8261368 Nanomanufacturing devices and methods  
Devices for performing nanofabrication are provided which provide small volume reaction space and high reaction versatility. A device may include a reaction chamber adapted for nanoscale...
8246966 Trypanosome microsome system and uses thereof  
The present invention provides cell free preparations of protozoan microsomes, wherein the cell free preparation of protozoan microsomes demonstrate the ability to translocate a protozoan...
8241866 Method for detection of microorganism and kit for detection of microorganism  
A kit is disclosed for preparing a measurement sample for detecting live cells, injured cells, VNC cells and dead microorganism cells in a test sample by the following steps: a) the step of...
8241865 Direct antimicrobial susceptibility assay with concurrent qualitation/quantitation  
An antimicrobial susceptibility assay enabling a more rapid and direct result, including an assay dish including at least one chamber, at least one growth medium carried by the assay dish, at...
8241644 In vitro model of latent mycobacterial infection  
A method of inducing latency in Mycobacterium permits preparation of an in vitro model system of latent mycobacterial infection. Latency is induced in a pure culture of Mycobacterium by exposing...