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7585617 |
Method and device for thermal conditioning of a cell
The invention relates to methods and agents for thermal conditioning of a biological cell, methods and uses of said agents for releasing and insulating ingredients outside the biological cell, and...
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7563565 |
Method of preparing bio-identical hormones
The embodied composition is a dose of bio-identical hormones in a solvent with a vasodilator, a hormone modulator, and a carrier for balancing and maintaining Cortisol level in a human. The dose...
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7510864 |
Decision-making spectral bioreactor
This invention fills several voids in bioreactor technology that allows efficient connection of aspects of physical science (optics, electronics, physical chemistry, sensors) to aspects of...
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7504252 |
Apparatus and methods for scanning and producing biological specimen film strips
A biological specimen film reel, a biological specimen film assembler, and a biological specimen scanner are provided. The biological specimen film reel comprises a reel carrying a film having a...
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7504230 |
Method of identifying a useful set of signal transduction proteins from a multiplicity of potentially useful proteins
The present invention is a cell-based method of identifying a set of signal transduction proteins having an intracellular localization pattern responsive to toxic compounds. The method requires...
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7501232 |
Method for cell selection
The invention relates to a method for the non-invasive selection of single living cells under gentle conditions from mixtures of cells or cell cultures with respect to a specific production...
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7435581 |
Integrated bio-reactor monitor and control system
Systems and methods for automatically controlling conditions of a process are disclosed. In one example, a controller is programmed with a sequence of steps and parameters required to carry out a...
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7393656 |
Methods and compositions for risk stratification
The present invention provides an approach for the simultaneous determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of...
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7381535 |
Methods and compositions for detecting receptor-ligand interactions in single cells
The invention provides methods and compositions for simultaneously detecting the activation state of a plurality of proteins in single cells using flow cytometry. The invention further provides...
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7354730 |
High-throughput assay of hematopoietic stem and progenitor cell proliferation
The present invention relates generally to kits that provide reagent mixes and instructions for the use thereof, in performing high-throughput assay methods that determine the proliferative status...
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7354729 |
High-throughput stem cell assay of hematopoietic stem and progenitor cell proliferation
The present invention relates generally to high-throughput assay methods that determine the proliferative status of hematopoietic stem and progenitor cells. The present invention further relates to...
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7314708 |
Method and apparatus for electronic synthesis of molecular structures
A self-addressable, self-assembling microelectronic device is designed and fabricated to actively carry out and control multi-step and multiplex molecular biological reactions in microscopic...
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7312089 |
Detection of erythropoietin and erythropoietin receptor
The invention is based on the development of several sensitive and simple methods for detecting erythropoietin and the erythropoietin receptor and associated antibodies. The methods and reagents...
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7270996 |
Automated bioculture and bioculture experiments system
The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system...
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7270947 |
Method for controlling biooxidation reactions
Biooxidation reactions can be controlled by a method which comprises the steps of: (1) independently adding a substrate and a co-substrate at predetermined rates to a bioxidation reaction mixture...
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RE39815 |
Method for determining ion channel activity of a substance
A method for determining the ion channel activity of a substance comprises the steps of (i) expressing the substance as a heterologous protein in a host cell, and (ii) determining changes in...
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7235353 |
Predicting hepatotoxicity using cell based assays
Cell based assays are used to assess the hepatotoxicity of a stimulus. Imaging technologies are used to analyze the effects of a stimulus on hepatocytes. Image analysis may characterize the...
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7217505 |
Method for determining whether condition is symptom of metabolic syndrome
The use of cortisol agonist for preparing a system for diagnosis of the metabolic syndrome and related conditions as belly fatness, insulin resistancy including increased risk of developing senile...
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7183108 |
Selection and uses of lactic acid bacteria strains modulating non-specific immunity
The invention concerns lactic acid bacteria strains capable of regulating the production of NO and inflammatory cytokines by enterocytes, depending on the inflammatory condition of said...
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7169599 |
Fluid interface for bioprocessor systems
An apparatus and method for an aseptic fluidic interface between bioprocess systems is provided. The apparatus includes an inlet valve, adapted for automatic control, that is coupled to a biofluid...
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RE39449 |
Apparatus for cryopreservation and recovery of red blood cells
A system dynamically adjusts the delivery rate of a cryopreservation solution to red blood cells to permit freezing. The delivery rate is preferably determined according to an equation that...
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7141421 |
Control of metabolism with human 2-oxoglutarate carrier
The present invention is directed to compositions and methods related to the use of human OGC as an uncoupling protein.
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7125658 |
Small protein that interacts with a ribonucleotide reductase subunit and uses thereof
The present invention provides for an isolated Sml1 protein or a homologue thereof. The present invention also provides for a screening assay for identifying compounds that are capable of reducing...
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7112403 |
Method for the identification of anesthetics
Human and mouse TREK-1 potassium transport proteins are disclosed as well a method for using potassium transport proteins for identifying substances having anesthetic properties, such as producing...
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7101719 |
Support and method for cell based assays
Disclosed is a method for the measurement of a cellular process, or for the measurement of the effect of a test compound on a cellular process, in one or more different populations of cells. The...
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7026132 |
Method of monitoring the effect of Cathepsin S inhibitors
The present invention relates to a method for monitoring the effect of in vivo administration of Cathepsin S inhibitors by measuring accumulation of an intermediate degradation product of invariant...
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7020560 |
Methods for cell-based combinatorial logic
A method for cell-based combinatorial logic includes the steps of providing at least one genetically engineered cell, the genetically engineered cell having at least one transcriptional unit. The...
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7011939 |
Apparatus and method for electrophysiological testing
A method and apparatus for running a plurality of tests concurrently to obtain data relating to the electrophysiological properties of receptors and channels in biological membranes of test...
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6984526 |
Spectrophotometric method for determining the viability of a sample containing platelets
A method and apparatus for characterizing the type of a blood sample and a variety of blood components are provided wherein a transmission spectrum of the sample is collected over a predetermined...
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6979733 |
Epoxide hydrolases, nucleic acids encoding them and methods of making and using them
The invention is directed to polypeptides having epoxide hydrolase activity, polynucleotides encoding the polypeptides, antibodies that bind to these polypeptides, and methods for making and using...
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6942963 |
Methods for identifying treatments for neurotoxicity in Alzheimer's disease caused by β-amyloid peptides
The invention involves identification of a mechanism of β-amyloid peptide cytotoxicity, which enables treatment of conditions caused by β-amyloid peptide aggregates by administration of compounds...
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6942962 |
Computer monitoring and control of fermentation
It is desirable to enhance reproducibility and control of batch fermentation processes. Some examples of these processes include: alcoholic beverage manufacture, and acetone and pharmaceutical...
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6921634 |
Replication competent hepatitus C virus and methods of use
The present invention provides a replication competent hepatitis C virus that includes a heterologous polynucleotide. The invention also includes methods for modifying a hepatitis C virus...
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6872516 |
Methods of producing carbon-13 labeled biomass
A method and apparatus for preparing uniform carbon-13 labeled biomass using a water soluble carbon-13 labeled carbon source, such as a [ 13 C]-bicarbonate or [ 13 C]-carbonate salt, is disclosed....
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6756198 |
Oligonucleotide for highly sensitive detection of hepatitis C virus and method for detection thereof
An oligonucleotide useful for specific amplification of HCV RNA, or highly sensitive detection and identification of HCV RNA, and a combination thereof. A detection method using RNA amplification...
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6713308 |
System for electrochemical quantitative analysis of analytes within a solid phase
The analytical process utilized in the system of this invention comprises three (3) step distinct steps wherein an analyte of interest in a test sample is initially labeled and subsequently...
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6696244 |
G-coupled receptors associated with retroviral entry into cells, and therapeutic uses thereof
The present invention provides two new HIV/SIV translocation promoting agents, Bonzo and BOB. The present invention also provides the amino acid and DNA sequences of human, African green monkey,...
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6667149 |
PROCEDURE FOR THE ANALYSIS OF THE FUNCTIONAL ACTIVATION OF LEUKOCYTES, PLATELETS AND OTHER CELLS, INDUCED IN VIVO OR IN VITRO, BASED ON THE STABILIZATION OF CYTOPLASMIC MEMBRANE PROTEINS AND ITS DETECTION USING QUANTITATIVE CYTOMETRIC METHODS IN THE ABSENCE OF ADDITIONAL SAMPLE MANIPULATION
Procedure for the study of the functional activation of leukocytes, platelets and other cells, produced in vivo or induced in vitro, based on the stabilization of cytoplasmic membrane proteins and...
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6589748 |
Method for kidney disease detection and treatment
A method is disclosed for diagnosing early stage of a disease in which an intact protein found in urine is an indicator of the disease. The method includes assaying urine sample to detect the...
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6586195 |
Method of detecting sugars
A method for detecting reducing sugars in samples using a test reagent containing an indicator capable of producing calorimetric changes when contacted with reducing sugars. Under alkaline...
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6461809 |
Methods of improving infectivity of cells for viruses
The present invention relates to cells which have improved receptivity to viruses which are capable of infecting them. Receptivity to such viruses is improved by selecting cells from a population...
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6447989 |
Kidney disease detection and treatment
A method is disclosed for diagnosing early stage of a disease in which an intact protein found in urine is an indicator of the disease. The method includes assaying urine sample to detect the...
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6444462 |
Incubation system for an analyzer apparatus
An ampoule incubator and light analyzer is provided which includes a housing having at least one receptacle for an ampoule, an incubation system, a light analysis system, and a master control...
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6436627 |
Gene encoding an invertebrate α1 calcium channel subunit
The present invention provides for the isolation and characterization of a calcium channel α, subunit gene cloned from Drosophila melanogaster , and designated “DmcalD” . . . an invertebrate...
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6410339 |
Preparation for diagnosis of the metabolic syndrome and diseases including the syndrome
The use of cortisol agonist for preparing a system for diagnosis of the Metabolic Syndrome and related conditions as belly fatness, insulin resistance including increased risk of developing senile...
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6383739 |
Method of identifying compounds capable of activating ISL production
The present invention is directed to an Immunodeficiency-virus Suppressing Lymphokine (ISL) produced by stimulated CD8+ PBMC, cloning and isolation of nucleic acid molecules for eukaryotic ISL, and...
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6376171 |
Methods of screening for antiviral compounds
The present invention demonstrates that the M2-1 protein of respiratory syncytial virus has a conserved Cys 3 -His 1 motif known to bind zinc ions in other proteins and that mutations of the...
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6361934 |
Method and apparatus for cryopreservation
A method of cryopreserving biological material, which method comprises providing a sample of the biological material, where a liquid phase of the sample includes at least one solute; lowering the...
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6358534 |
Immunotolerant prothrombin complex preparation
The invention relates to an immunotolerant prothrombin complex preparation, a method of producing this preparation, as well as the use of the preparation for producing a medicament,
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6355413 |
Method for determining ion channel activity of a substance
A method for determining the ion channel activity of a substance comprises the steps of (i) expressing the substance as a heterologous protein in a host cell, and (ii) determining changes in...
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