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5240854 |
Continuous high-density cell culture system
A multi-chamber cell-culture assembly has provision for even and continuous distribution of nutrient medium throughout each of the chambers. A device is constructed to provide large surface areas...
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5236567 |
Enzyme sensor
An enzyme sensor, which comprises an enzyme-modified electrode and a counter electrode, wherein the enzyme-modified electrode comprises, as electrode components, an enzyme and/or an...
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5232838 |
Culture media device and method of use
A culture media device comprised of a body member including self-supporting substrate, and coated on its upper surface with a layer of water-based adhesive composition and a layer of a...
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5217900 |
Biological reactor
A biological reactor which is operated using microorganisms and/or enzymes and used for the oxidative conversion of organic compounds, and in which the organic compounds to be converted are...
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5211850 |
Plasma filter sorbent system for removal of components from blood
A system and method of achieving both convective and diffusive transport of plasma across a membrane accompanied by the selective removal of plasma components using sorbents followed by reinfusion...
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5187095 |
Apparatus for culturing animal cells
An apparatus for the in vitro culture of animal cells to recover secreted proteins of interest therefrom, affording the capability of being readily and predictably scaled up or down to desired...
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5178758 |
Biochemical water filter
A biochemical water filter comprising a cylindrical shell, a solar light tube and several ultraviolet tubes disposed in the shell so as to cultivate nitric bacteria to get rid of harmful bacteria...
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5168058 |
Cell culture carriers and method of use
The invention relates to packing material for use in the cultivation of anchorage-dependent cells, which require a solid surface for proliferation. The packing material of the invention is provided...
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5166072 |
Apparatus for the cultivation of immobilized micro-organisms
An apparatus for cultivating immobilized micro-organisms consisting of a fluidized bed reactor with fittings for gassing and a retainer system for the immobilized biocatalysts. The fluidized bed...
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5160705 |
Apparatus for fluidizing granular material
A device for the introduction of a liquid in a medium containing granulate material for the fluidization of this material, intended more particularly for equipping reactors such as those used for...
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5159694 |
Portable reactor for carrying out gas-evolving biotechnological processes or gas consuming processes while maintaining a packed fixed-bed arrangement
The coalescence and release of bubbles from packing that supports the growth of microorganisms is promoted by mechanical action on the packed bed arrangement, in particular by continuous or...
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5143847 |
Enzyme-fixed bioreactor
An enzyme-fixed bioreactor, including a reaction column, enzyme-fixed catalyst particles uniformly and densely filled in the reaction column, the catalyst particles being composed of carrier...
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5132090 |
Submerged rotating heat exchanger-reactor
An apparatus transfers heat for the purpose of purifying raw feed liquid, separating dissolved gases from liquids, vaporizing heat transfer fluids or containing and regulating biological/chemical...
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5085766 |
Filter for cleaning fluids
The filling of a filter for removing contaminants from air and other fluid is constituted by hanging freely-moving foil strips coated with active carbon and provided with a microorganism culture...
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5081031 |
Synthetic polypeptide with type IV collagen activity
A polypeptide having the following formula is provided: leu-ala-gly-ser-cys-leu-ala-arg-phe-ser-thr-met which can bind heparin and promote cellular adhesion. Medical devices such as prosthetic...
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5081036 |
Method and apparatus for cell culture
Methods and apparatus are provided for growing both suspension type cells and anchorage dependent cells in airlift bioreactors. A packing means, such as stainless steel wool, is provided in the...
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5073491 |
Immobilization of cells in alginate beads containing cavities for growth of cells in airlift bioreactors
Method and apparatus are provided for immobilizing and growing cells in airlift bioreactors to obtain increased cell density. Cells are immobilized by forming alginate beads containing cells and...
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5057428 |
Bioreactor
A bioreactor comprises a cylindrical tank, a cylindrical mesh member arranged inside the tank concentrically therewith so that the mesh member separates an inner space of the tank into an outside...
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5043283 |
Fluidized bed cell culture apparatus with a drain valve for the removal of support material
Cell culture apparatus comprises a fluidized bed culture tank body in which cell attached porous material is fluidized by air flow, and a pre-culture tank for supplying medium to the fluidized bed...
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5028541 |
Flow-through cell cultivation system
A flow-through cell cultivation apparatus and method is described. The flow-through cell cultivation system comprises a flowcell, a chamber inside the flowcell for holding cells, and a flowcell...
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5010004 |
Method for continuous reaction with fluidized immobilized lipase
A water-soluble substrate and an oily substrate are continuously reacted with immobilized lipase in a reaction vessel having vertically maintained apart upper and lower conically-shaped regions,...
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4999302 |
Biological contact gas scrubber for waste gas purification
Process and apparatus is disclosed for removing pollutants from a waste gas stream comprising culturing in a rotary biocontactor a biomass capable of assimilating the pollutants and producing...
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4963494 |
Enzyme immobilization in an anisotropic ultrafiltration membrane
An enzyme immobilized membrane comprising an anisotropic ultrafiltration membrane having a porous layer and a dense layer, and an enzyme immobilized therein is disclosed. The porous layer of the...
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4959148 |
Method and apparatus for specific affinity enhanced transport bioreactor
A method and apparatus for removing and/or modifying specific target substances in the blood is disclosed. The invention includes a column or chamber in which selected bioreactant molecules are...
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4925803 |
Fibrous roll of tubular braid for immobilization of cells and enzymes
A fibrous support for immobilizing enzymes and cells is prepared as a roll formed by winding a braid on a tubular frame member. The braid is formed in a tubular shape with a plurality of rovings...
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4904600 |
Bioreactor for continuous processing of a reactant fluid
A bioreactor and method of its operation are described comprising a vertical column with a lower reaction section filled with column packing particles classifiable by means of their differential...
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4902624 |
Temperature cycling cuvette
There is disclosed a thermal cycling cuvette constructed with an improved sample fluid thermal time constant. The fluid surface-to-volume ratio, and the cuvette thermal path length and thermal...
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4898718 |
Biocatalytic reactors for gel-like and other types of immobilized biocatalysts
The present invention provides a new biocatalytic reactor to utilize succfully insoluble biocatalysts to carry out enzymatic reactions. It is especially adequate for the processing of enzymatic...
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4892818 |
Bioreactor
A bioreactor and method of its operation are described comprising a vertical column with a lower reaction section filled with column packing particles classifiable by means of their differential...
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4861725 |
Mammalian cell culture apparatus
A cell culture apparatus includes a sealed container in which a plurality of porous tubular members are positioned. The tubular members are arranged concentrically. A removable sampling bar is...
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4833083 |
Packed bed bioreactor
A bioreactor for anchorage or nonanchorage dependent cells or for immobilized enzymes that is capable of achieving high cell densities or concentrations of reaction products is disclosed. The...
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4829002 |
System for metering nutrient media to cell culture containers and method
A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In...
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4822741 |
Biocompatible polyorganosiloxane composition for cell culture apparatus
A polyorganosiloxane composition having a biocompatible surface thereon is disclosed. The biocompatible surface results from the derivatization, or amination, of the surface intended for cell...
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4810653 |
Cuvette with non-flexing thermally conductive wall
There is disclosed a cuvette constructed with an improved sample fluid thermal time constant, featuring a flexible heat transfer wall. To prevent such wall from deforming under pressure generated...
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4806148 |
Apparatus for biological treatment of waste gases
An apparatus for removal of malodorous and/or toxic components from wast gases by biological treatment of the same. Such removal is accomplished by passing the gas stream through a humidifying...
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4789634 |
Carrier for the cultivation of human and/or animal cells in a fermenter
A carrier for the cultivation of animal and/or human cells in a fermenter, comprises a polymer base body of a solid formed into a pressure-resistant matrix, with a capillary system for carrying the...
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4734111 |
Process and apparatus for cleaning styrene-polluted spent air
A process for cleaning in particular styrene-polluted spent air by filtering out styrene and an apparatus for performing this process are described. The filter used is a biofilter of tree bark,...
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4728502 |
Apparatus for the chemical synthesis of oligonucleotides
Apparatus for carrying out a multiplicity of different sequential chemical syntheses on solid-supports simultaneously comprises a multiplicity of complementary support plates each formed with a...
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4689302 |
Spiral designed reactor
A flow reactor for reacting a feedstock with a proteinaceous preparation immobilized on and within the pores of a support medium while traversing a spiral path between adjacent turns of said...
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4680263 |
Continuous alcohol manufacturing process using immobilized microorganism
A feed liquid (sugar-containing liquid) is continuously fed to a fermenter packed with an immobilized microorganism, which is obtained by immobilizing an alcohol producing microorganism on a...
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4670140 |
Fixed bed reactor column for anaerobic decomposition processes
A fixed bed layer of a reactor column for the execution of anaerobic decosition processes, which column is divided by screen partitions into segments one above another with intermediate spaces for...
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4665027 |
Immobilized cell reactor-separator with simultaneous product separation and methods for design and use thereof
A novel immobilized cell reactor design is described capable of separating an inhibitory metabolite from a fermentation broth as it is formed. This reactor has the dual advantages of (1) speeding...
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4661458 |
Cell culture system
A device is described which provides a totally enclosed and secure environment for the culture of cells and for the production of biologicals, pharmaceuticals, and other cell-derived products of...
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4632758 |
Anaerobic wastewater treatment system
An anaerobic apparatus for treating wastewater is disclosed. The treating apparatus comprises a reactor housing a media having a plurality of surfaces for receiving bacteria. The wastewater that is...
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4604361 |
Reactor for producing gas by means of micro-organisms
A column reactor, suitable for continuous production of a gaseous reaction product by contacting a liquid reaction medium with a gas-forming agent fixed to a reaction plug comprising a solid...
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4603109 |
Method and apparatus for contacting reactants in chemical and biological reactions
The present invention is directed to novel methods and apparatus for conducting chemical and biological reactions. A reactor is provided that includes a reaction matrix member formed from...
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4561974 |
Apparatus for the anaerobic filtration of waste water
An apparatus for the anaerobic filtration of waste water includes a filter of filling material through which the waste water to be treated is passed from the bottom to the top. The filter includes...
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4546083 |
Method and device for cell culture growth
A cell culture device is disclosed for the cultivation of animal, plant, microbiological or artificial cells. The device involves a three-dimensional arrangement of fibers within a housing arranged...
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4537860 |
Static cell culture maintenance system
A method and apparatus for maintaining animal cells in vitro in a substantially arrested state of proliferation with continuous secretion of cell product is disclosed. The cells are retained within...
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4514499 |
Cell culture using a monolithic support
A novel immobilized cell composite used in a novel apparatus/method for cell culture. The composite comprises: (a) a high surface area monolithic support having a multiplicity of mutually...
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