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7358082 |
Device and method for culturing cells
An object of the present invention is to construct a culture device optimized for culturing animal cells. The present invention provides a device for culturing cells which comprises at least one...
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7358078 |
Auto microfluidic hybridization chip platform
An auto microfluidic hybridization chip platform is disclosed to provide a hybrid reaction test system with the features of fast reactions, automatic operations, and a convenient platform. The...
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7326564 |
Flow system for medical device evaluation and production
In some embodiments, a flow system includes a medical device mount, fluid and a conduit containing the fluid and medical device mount. The conduit is mounted on an assembly that moves the conduit...
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7294503 |
Microfabricated crossflow devices and methods
A microfluidic device for analyzing and/or sorting biological materials (e.g., molecules such as polynucleotides and polypeptides, including proteins and enzymes; viruses and cells) and methods for...
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7288405 |
Devices and methods for pharmacokinetic-based cell culture system
Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.
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7270996 |
Automated bioculture and bioculture experiments system
The present invention provides a feedback controlled bioculture platform for use as a precision cell biology research tool and for clinical cell growth and maintenance applications. The system...
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7264962 |
Enzymatic cascade bioreactor
Disclosed is an apparatus and method for continuously converting sucrose to β-D-glucose. The method comprises a three stage enzymatic reactor in which an aqueous solution of sucrose is first...
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7256035 |
System for thermocycling of fluids in cartridges
System for thermocycling of fluids in cartridges comprising a thermocycling unit in thermal contact with a first substantially planar and heat conducting wall of a cartridge, a light source for...
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7247470 |
Method and apparatus for measuring nitric oxide production and oxygen consumption in cultures of adherent cells
An apparatus and method for measuring nitric oxide production and oxygen consumption in cultures of adherent cells continuously and without destroying the cells. The method involves flowing growth...
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7235400 |
Laminated microarray interface device
A device for forming a low volume reaction chamber on a substrate such as a microarray slide and its method of use is disclosed. The reaction chamber forming device has an adhesive laminate design...
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7179637 |
Apparatus and method for using intestinal segments or their substitutes in high-throughput analysis of compound absorption
An apparatus for high-throughput analysis of compound absorption in a controlled environment that closely resembles in-vivo conditions. The apparatus includes at least one tissue-receiving...
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7091035 |
Cell culturing and storage systems, devices and methods
Featured is a long-term cell culture system being configured and arranged so as to be capable of monitoring the dynamic processes that occur during proliferation and differentiation of stem cells...
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7056725 |
Vegetable alga and microbe photosynthetic reaction system and method for the same
A vegetable alga and microbe photosynthetic reaction system and method for the same is used for vegetable algae and microbe cultivation liquid and algae seeds infused herein to circularly conduct...
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6991628 |
Device and method for creating a vascular graft in vitro
Methods and apparatus are provided for forming a vascular graft in vitro by axially distending a blood vessel to induce growth. The apparatus comprises a chamber containing a tissue culture medium,...
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6946287 |
Device for providing a hybridization chamber, and process unit and system for hybridizing nucleic acid samples, proteins, and tissue sections
A device ( 1 ) is disclosed for providing a hybridization chamber ( 2 ), for hybridizing nucleic acid samples, proteins, or tissue sections on a slide ( 3 ), which is implemented so that it is...
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6881569 |
Apparatus and method for evaluating tissue engineered biological material
An apparatus and method that allows the visualization of leakage of cell culture media through a conduit wall of a tissue-engineered biological construct such as a semilunar heart valve or valve...
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6864084 |
Bioreactor and method for fluidly suspending a product
A method for floating at least one substance for growing a tissue part in a bioreactor. The method includes providing at least one substance consisting of one of a tissue part, a scaffold having...
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6767734 |
Method and apparatus for producing age-synchronized cells
The present invention relates to a method and an apparatus for producing cell population of the same chronological age. Cells of a predetermined age are collected onto an array of surfaces. The...
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6670169 |
Bioreactor
A bioreactor with a reaction container ( 1, 1 a , 1 b , 1 c ) for a substance (C) to be acted upon with a medium has a pump ( 5, 5 a , 5 b , 5 c , 5 d ) for conveying the medium. The pump is...
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6645759 |
Apparatus for growing cells in culture under shear stress and/or strain
Disclosed is a cell culture device for inducing shear stress and/or strain on cells. The device includes a cell culture membrane and a flow pathway for moving fluid across cells growing on the...
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6632658 |
Bioreactor and method for fluidly suspending a product
The method for the holding in flotation of a substance such as a tissue part in a bioreactor ( 61 ) is characterized in that the substance ( 73 ) is acted upon with a fluid; and in that the flow of...
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6627435 |
Perfusion incubator
A perfusion incubator having a fluid conditioning unit ( 12 ), a well assembly ( 7 ) and a well assembly heating unit ( 14 ), a peristaltic pump ( 4 ) and a fluid collection unit ( 11 ). The well...
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6617151 |
Method of closing a cell containment device with a wet seal
A method is provided for closing a containment device that involves wetting at least a portion of a permeable polymeric membrane such as tubular membrane with a liquid such as a cell suspension or...
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6599736 |
Configurable microreactor network
The configurable microreactor network of the invention comprises a substrate in which a plurality of overpassing channels are arranged. Said channels are optionally interconnectable via connecting...
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6562616 |
Methods and devices for cell culturing and organ assist systems
The invention relates to new flow-through cell culturing devices that include plates arranged in parallel and spaced to control the flow patterns and velocity of liquid medium flowing between the...
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6555359 |
Process for the anaerobic treatment of flowable and nonflowable organic waste
A method and apparatus for anaerobic treatment of organic wastes in a liquid filled vessel wherein particles of the waste are buoyed and form a floating bed in the liquid by the gasses generated by...
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6524849 |
Biological filter structures
A biological filter element includes a support element of generally ellipsoidal configuration. The support element has two opposite polar regions and includes a medial ring intermediate the two...
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6492135 |
U-shape and/or nozzle u-loop fermentor and method of carrying out a fermentation process
A U-shape and/or nozzle-U-loop fermentor has a U-part consisting of an essentially vertical downstream part ( 2 ), an essentially vertical upstream part ( 4 ), a U-shape bend part ( 3 ) which...
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6358729 |
Compact plant for the removal of odorous substances from polluted air
A compact plant for the depuration of polluted air, in particular from odorous substances, comprising a unitary housing in which are placed, in sequence, a prescrubbing section, a filtering bed and...
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6319706 |
Process and apparatus for remedying polluted media
A process to remedy a polluted medium includes contacting a first medium containing a pollutant with a second medium containing a microorganism which is capable of decomposing the pollutant. A...
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6261771 |
Method and apparatus for detection of multiple nucleic acid sequences and multiple antigens
A method and apparatus for detection of multiple target nucleic acids and/or antigens such as hormones, antibodies, or nerve agents in a sample, involves presenting the sample to a plurality of...
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6207445 |
Filtration and extraction device and method of using the same
The present invention involves a simple, disposable, manual filtration and extraction device and method of use that provides a sample directly to an analytical method. The device is capable of...
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6174720 |
Modified bioreactor
Bioreactor apparatus for culture of living matter in a liquid medium includes a plurality of tubes connected at one end to a primary manifold section and at their other end to a secondary manifold...
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6174719 |
Cardiovascular bioreactor apparatus and method
The invention involves a method and apparatus for processing biological material, such as heart valves and vascular grafts.
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6143556 |
Enzyme systems for gas processing
The invention provides a process for gas separation wherein a selected gas in a mixed gas stream is contacted by an enzyme having an active site directly contacted by the mixed gas stream, and the...
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6069004 |
Circulatory microorganic deodorizing system
A circulatory microorganic deodorizing system has the inner space of a tower main body partitioned into an upper deodorization chamber, a middle level deodorization chamber, and a lower...
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6037170 |
Apparatus for culturing microalgae
An apparatus for culturing microalgae is characterized by comprising: (1) a waterway a to be filled with a suspension containing a culture solution and microalgae and adapted to be irradiated...
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5866399 |
Process for inactivating carboxypeptidase Y in hirudin-containing culture broths
The present invention relates to a process for inactivating Carboxypeptidase Y (CPY) in a hirudin-containing culture broth produced by fermenting a transformed yeast. It has been found that...
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5846817 |
Bioreactor, in particular for microgravity
A bioreactor, in particular for a microgravity, comprising at least one cell culture chamber, an oxygen supply and an agitator for a cell culture. In particular, the chamber includes two housing...
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5843766 |
Apparatus for the growth and packaging of three dimensional tissue cultures
A tissue culture chamber is disclosed. The chamber is a casing that provides for growth of three-dimensional tissue, and more specifically for the growth of skin tissue, that can be grown,...
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5763267 |
Apparatus for the large scale growth and packaging of cell suspensions and three-dimensional tissue cultures
An apparatus for the large scale culturing and packaging of cell suspensions, three dimensional tissue, and other biological systems is disclosed. The apparatus includes a plurality of flexible or...
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5716842 |
Miniaturized flow thermocycler
A miniaturized thermocycler is provided for carrying out thermally controlled biochemical or biological melecular processes, in particular polymerase chain reactions. The aim of the invention is to...
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5645801 |
Device and method for amplifying and detecting target nucleic acids
Methods, devices, apparatus and kits for amplifying and detecting nucleic acid are provided. The apparatus is a thermal cycling device that operates in conjunction with a reaction/detection unit. A...
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5614378 |
Photobioreactors and closed ecological life support systems and artifificial lungs containing the same
A photobioreactor system for efficient oxygen production for a closed ecological life support system (CELSS) is disclosed. Special features of this system include, e.g., the optical transmission...
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5512480 |
Flow-through bioreactor with grooves for cell retention
The invention is a flow-through bioreactor for the retention and culture of cells in perfused media. The bioreactor is a generally rectangular vessel with inlet and outlet ports in the lid allowing...
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5510257 |
Hollow fiber immobilization with chopped microporous hollow fibers
Most of the problems of prior art techniques for growing cells in hollow fiber devices can be avoided by growing the cells in short lengths (e.g., two inches (5.0 cm.) or less) of microporous...
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5486475 |
Membrane module to remove gaseous substances from a gas stream
A membrane module is provided which serves to remove gaseous substances from a gas stream and which consists of a plurality of plane membrane pockets consisting of a gas-permeable, liquidproof...
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5482860 |
Apparatus for continuously removing oxygen from fluid streams
The present invention is directed to an apparatus for removing oxygen from a fluid stream. The apparatus is comprised of a flow through reactor chamber containing a sufficient amount of oxygen...
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5459069 |
Device for maintaining and growing human stem and/or hematopoietics cells
Devices are provided for the growth of human stem and/or hematopoietic cells in culture. Bioreactors are provided in which diverse cell types are simultaneously-cultured in the presence of...
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5334497 |
Method of feeding a substrate into tubular bioreactor
A method of feeding substrates into a tubular bioreactor incorporating a reacting vessel and a separating membrane in which the reaction and separation or collection can be continuously and surely...
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