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8183009 |
Assaying cellular markers for the evaluation of tumors
An improved system for assaying expression of various markers, factors or antigens on the cultured cells for diagnostic purposes and for using such expression to monitor the applicability of...
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8183006 |
Screening method for identifying new aminoacyl-tRNA synthetase inhibitors
The method comprising: a) obtaining a gene sequence codifying a naturally occurring aminoacyl-tRNA synthetase; b) engineering the gene codifying for said aminoacyl-tRNA synthetase, resulting into...
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8178315 |
Lyophilized edible food incorporating a marker and methods of making
A standardized, lyophilized edible food containing a biologically safe stable marker for use in the measurement of gastric emptying by the quantification of marker excreted in the breath of the...
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8178089 |
Neuronal progenitors from feeder-free human embryonic stem cell culture
The present invention relates to methods for producing feeder cell-free neuroprogenitor cells (preferably adherent) from embryonic stems cells, preferably human embryonic stem cells, the feeder...
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8173438 |
Microbiological assessment method and device utilizing oxygen gradient sensing
There is disclosed a biological indicator (BI) test utilizing oxygen sensing within a microenvironment as a means for determining the presence of viable microorganisms capable of growth, a method...
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8173387 |
Method of examining chemical using gene-disrupted strain
A method having higher sensitivity in a bioassay method utilizing cell response of a microorganism, for detecting the presence of a chemical in a test specimen is provided. The method of the...
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8163562 |
Photon reducing agents for fluorescence assays
The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon...
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8158377 |
Biosensor method and system based on feature vector extraction
A method of biosensor-based detection of toxins comprises the steps of providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a...
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8158378 |
Utilizing waste tail gas from a separation unit biogas upgrade systems as beneficial fuel
The invention relates to a method for utilizing low-quality tail gas derived from a pressure swing adsorption system or membrane system, which is used to upgrade biogas, as a beneficial fuel for...
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8152992 |
Cell-based sensing: biological transduction of chemical stimuli to electrical signals (nose-on-a-chip)
Methods and compositions for the reliable detection of chemical stimuli using a “nose-on-a-chip” are presented. The invention uses cells sensitive to chemical stimuli and detects and processes the...
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8153393 |
Spirolactam targeting compounds and related compounds
Spirolactam targeting compounds, related compounds, uses of such compounds, and methods of making such compounds are disclosed.
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8153427 |
Cardiomyocytes and methods of producing and purifying cardiomyocytes
The invention provides methods for producing a culture of cardiomyocytes and cultures of cardiomyocytes. Exemplary methods of producing and cultures of cardiomyocytes include a population of cells...
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8153610 |
Sulfoglycolipid antigens, their extraction from Mycobacterium tuberculosis, and their use against tuberculosis
The present invention relates to compounds of the following general formula: (I) wherein R1 and R2 are fatty acyl groups, a process to extract them from Mycobacterium tuberculosis, and their use in...
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8148092 |
System and method for performing G protein coupled receptor (GPCR) cell assays using waveguide-grating sensors
The present invention includes a system and method that uses optical LID biosensors to monitor in real time agonist-induced GPCR signaling events within living cells. Particularly, the present...
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8148167 |
Fluorescent pH detector system and related methods
Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.
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8148101 |
Method for classifying and counting bacteria in body fluids
A method for distinguishing erythroblasts from bacteria by automated hematology analyzers, such as, for example, the CELL-DYN® 4000 automated hematology analyzer and the CELL-DYN® Sapphire™ aut...
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8143019 |
Portable microbiological testing device for gases
A method and apparatus for microbiological testing of biogas and other gaseous streams in which a liquid bacteria growth medium disposed within a lower region of a portable sampling vessel is...
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8143018 |
Method for preparing a measurement sample for detecting live cells of a microorganism in a test sample
According to the following steps, live cells, injured cells, VNC cells and dead cells of a microorganism in a test sample are detected by flow cytometry: a) the step of treating the test sample...
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8143017 |
Method of measuring the ability of a sample to withstand reactive oxygen species (ROSS)
A method of measuring the ability of a biological sample to withstand reactive oxygen species (ROSs). The method includes at least the steps of putting the sample for testing and a photosensitive...
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8143060 |
Method of assessing the viability of thawed developmentally competent embryos
The invention relates to a method of assessing the viability of a thawed cell wherein the cell is a gamete, an embryo, a karyoplast, a putative stem cell population, a stem cell precursor...
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8137904 |
Light emitting microorganisms and cells for diagnosis and therapy of diseases associated with wounded or inflamed tissue
Described is the use of a microorganism or cell containing a DNA sequence encoding a detectable protein or a protein capable of inducing a detectable signal, e.g., a luminescent or fluorescent...
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8138321 |
Acetolactate synthase (ALS) selectable marker from Trichoderma reesei
A nucleic acid encoding an acetolactate synthase (ALS) protein that provides resistance to ALS inhibitors, e.g., sulphonylurea and imidazolinone compounds, is provided. The nucleic acid may be used...
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8137526 |
Method of making an electrochemical nanowire assembly and attaching cells thereto
A method of growing a crystalline nanowire is disclosed. The method includes providing a pair of electrodes, immersing the electrode pair in a salt solution, and selectively applying a voltage...
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8133698 |
Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation
A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily...
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8129138 |
Method and apparatus for determining an analyte in a liquid sample
A method for the determination of an analyte in a liquid sample, especially a body liquid sample, with the aid of an analytical apparatus. The apparatus receives a first measuring signal si (i=0,...
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8129137 |
Two-photon probe for real-time monitoring of intracellular free zinc ions, method for preparing the probe and method for real-time monitoring of intracellular free zinc ions using the probe
A two-photon probe for real-time monitoring of intracellular free zinc ions is provided. The two-photon probe is represented by Formula 1: wherein R is H or OCH3. The two-photon probe has high...
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8124032 |
Microfluidic device and method of using same
The invention relates to a microfluidic device comprising one or more fluid channels, one or more fluid ports, and a V-shaped particle retention structure. The fluid channel is generally opposite...
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8119362 |
Method of screening for compounds that can be used for the treatment of respiratory conditions
The present invention relates to the use of a screening method for identifying candidate molecules that can be used for the treatment of respiratory conditions in a mammal, wherein the screening...
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8119116 |
Therapeutics for cancer using 3-bromopyruvate and other selective inhibitors of ATP production
The present invention relates to methods of treating a cancerous tumor using selective inhibitors of ATP production. The present invention also relates to pharmaceutical preparations comprising...
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8114625 |
Method for cell analysis
The invention describes a method for cell analysis in which the cells to be analyzed are adhesively applied to a slide and stained with a first stain. A first digital image is then taken and stored...
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8114662 |
Ion-selective quantum dots
The invention provides ion-selective sensors comprising quantum dots capable of selectively measuring ions, e.g., Na+, K+, Cl−, etc., in various environments, including in the cytosol of a living c...
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8114350 |
Sensors for detecting substances indicative of stroke, ischemia, infection or inflammation
A system is disclosed that extracts bodily fluid to a reaction chamber for monitoring a substance or property of the patient fluid. In one embodiment, a pump is used to advance the sample of bodily...
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8110177 |
Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
Disclosed is a method of treating small intestinal bacterial overgrowth (SIBO) or a SIBO-caused condition in a human subject. SIBO-caused conditions include irritable bowel syndrome, fibromyalgia,...
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8105581 |
Compositions and methods for inducing neuronal differentiation
The present invention provides compositions and methods for inducing neuronal cell differentiation.
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8097404 |
Composition and method for cell permeabilization comprising N-octyl-β-D-glucopyranoside, sodium polyphosphates, rubidium chloride and/or lithium chloride for detecting living cells on a membrane
The present invention relates to a composition for the permeabilization of the walls of microorganisms comprising the combination of octyl-β-D-glucopyranoside (NOG), sodium polyphosphates (HMP), ...
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8097433 |
Diagnostic composition and article for monitoring intravaginal infections
The present invention provides a non-toxic diagnostic composition for intravaginal monitoring of vaginal infections. The present invention further provides a diagnostic article for intravaginal...
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8093015 |
Method for determining the viability of cells in cell cultures
The invention relates to a method for determining the viability of cells in cell cultures, said method comprising the steps of: coloring the sample with a dye which can penetrate into individual...
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8088715 |
Detection of circulating tumor cells in peripheral blood with an automated scanning fluorescence microscope
An automated, highly sensitive, specific and potentially quantitative detection method using an automated microscope for identifying and enumerating rare cancer cells in blood and other fluids.
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8084222 |
Methods for generating host cells
The present disclosure provides compositions and methods comprising cells producing glycoproteins with variant glycosylation patterns. The methods and compositions may be used in producing...
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8084268 |
Method of evaluating the potential of the skin for scavenging free radicals
A substrate is filled with a reagent that presents a stable free radical character, and that is capable of producing a visible reaction in the presence of at least one free radical scavenger...
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8076090 |
Label free biosensors and cells
Disclosed are compositions and methods for using label free optical biosensors for performing cell assays. In certain embodiments the assays can be performed in high throughput methods and can be...
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8071382 |
Porous nanofiber mesh for three-dimensional cell culture
Disclosed is a mesh for cell culture in which linear nanofiber is cross-linked to form a network, wherein the linear nanofiber is composed of polyhydroxyalkanoate; or polyhydroxyalkanoate, and...
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8067231 |
Clostridial toxin activity assays
Compositions useful for detecting Clostridial toxin activity comprising a cell that contains an exogenous Clostridial toxin substrate which comprises a fluorescent member, a membrane targeting...
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8067154 |
Method and device for rapid detection of microorganisms by changing the shape of micro-colonies in micro-channels
This invention describes a method of rapid detection of micro-colonies of microorganisms by changing their shape from a regular semi-sphere to a long and thin cylinder. Cells are trapped by...
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8067184 |
Optoelectronic detection system
The invention described herein provides methods for the detection of soluble antigens. In particular, the methods provide for the detection of soluble proteins and chemicals. In addition, the...
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8048620 |
Method for enhancing the detection of contamination in a cellular blood product by covalently binding a hydrophilic polymer to the cell membrane
A method for preventing bacterial biofilm formation in a blood product, the method comprising modifying a blood product with a polymer selected from the group consisting of polyethylene glycol...
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8043823 |
Methods of identifying agonists and antagonists of hTASR bitter taste receptors
The present invention relates to agonists of the human bitter-taste receptors hTAS2R46, hTAS2R47 and hTAS2R50 and their role in bitter taste transduction. The invention also relates to methods for...
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8041515 |
Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
The present invention provides methods of multi-dimensional profiling of biologically active agents and determining their effects on biological systems. The methods of the present invention include...
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8039227 |
Peptide biomarkers predictive of renal function decline and kidney disease
Methods for diagnosing a kidney disease, or the risk thereof, in a subject are provided. The methods comprise determining an amount of at least one peptide biomarker disclosed herein in a...
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8030002 |
Methods for diagnosing pervasive development disorders, dysautonomia and other neurological conditions
Methods for aiding in the diagnosis of disorders including, but not limited to, PDDs (Pervasive Development Disorders), Dysautonomic disorders, Parkinson's disease and SIDS (Sudden Infant Death...
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