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5798215 |
Device for use in analyte detection assays
A device and method for its use in diagnostic assays are provided. The device comprises at least one assay path, where an assay path includes a main flow path and at least one side reagent channel....
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5798263 |
Apparatus for quantifying dual-luminescent reporter assays
The presently disclosed invention is drawn to an automatic luminometer apparatus capable of measuring two distinct luminescent reactions from within a single, non-compartmentalized sample...
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5792653 |
Substrate for cell structures
In an apparatus for culturing cells which comprises a plate-like body with a lattice structure having openings separated from one another by sidewalls and a bottom disposed on one side of the...
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5789183 |
Serological detection and identification of rice blast
Monoclonal antibodies (MAbs) useful in the serological detection and identification of rice blast were produced by hybridoma cells formed from fusions of myeloma cells with splenocytes from BALB/c...
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5789261 |
Solid phase immunoassay
Solid supports for solid phase immunoassays comprise polyethyleneimine-coated negatively charged polymeric materials. The combination of negatively-charged polymer support and polyethyleneimine...
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5784193 |
Microscope slide with removable layer and method
A slide for depositing for observation material under a microscope comprising a mounting surface to receive material for observation and a removable layer on the mounting surface formed with at...
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5780248 |
Foil sealed cassette for agglutination reactions and liner therefor
A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a...
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5770440 |
Apparatus for the early detection of microorganisms
The present invention describes an apparatus for detecting microorganisms in a culture container. The container includes a block having a plurality of through holes for dividing the sample into a...
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5766553 |
Test sample card
A test sample card has a fluid passage network provided on both sides of the card to provide for maximum separation distance between adjacent growth wells. The card also has cored sections along...
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5746980 |
Test sample card with improved air bubble evacuation
An improved sample card is provided. The improved card, typically used in biochemical analysis, achieves high sample well capacity and improved fluid flow, including by means of a plurality of...
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5741463 |
Apparatus for preventing cross-contamination of multi-well test plates
A multi-well plate which prevents cross-contamination of samples through the use of a resilient gasket which covers a majority of the top of the plate and is compressed by a lid having a clamp...
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5731212 |
Test apparatus and method for testing cuvette accommodated samples
A cuvette based testing device for use in testing or otherwise analyzing a fluid sample. A cuvette is provided that defines at least one conduit, wherein the fluid sample is introduced into the...
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5721136 |
Sealing device for thermal cycling vessels
A sheet of material seals vessels for biochemical reactions which undergo thermal cycling, and comprises a multilayer composite sheet which is placed over the openings of one or more reaction...
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5716825 |
Integrated nucleic acid analysis system for MALDI-TOF MS
An integrated nucleic acid sample analysis system for matrix-assisted laser-desorption/ionization time-of-flight mass spectroscopy (MALDI-TOF MS) is described. The integrated system comprises a...
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5698406 |
Disposable device in diagnostic assays
A disposable diagnostic device and method of its use are provided. The device comprises a housing containing first and second flow paths orthogonal to each other. The first flow path commences at a...
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5691194 |
Method and apparatus for in vitro fertilization
This invention relates to a method and apparatus for concentrating motile erm from a sperm sample, including concentrating sperm in the vicinity of one or more oocytes for in vitro fertilization....
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5691158 |
System and method for determining efficacy of sunscreen formulations
A system and method is disclosed employing a full thickness skin model for determining minimum sun protection factors (SPFs) of various sunscreen formulations by measuring the release of an...
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5681741 |
In situ PCR amplification system
A complete in situ PCR system for amplification of nucleic acids contained in a prepared cell or tissue sample. The containment system for the PCR sample comprises a glass microscope slide, a...
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5679310 |
High surface area multiwell test plate
The present invention comprises a microtiter plate formed of a substantially rigid, polymeric plate having a substantially flat upper surface and a regular array of similar wells, typically either...
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5679570 |
Device for performing urease tests on combined antrum/corpus biopsies to diagnose gastrointestinal illnesses
A device for carrying out urease tests for combined antrum/corpus biopsies to diagnose gastro-intestinal illnesses has a carrier plate, a schematic representation of the stomach on the plate, at...
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5670118 |
Color coded test wells
A method and procedure for color coding cuvettes used in laboratory tests without contaminating the interior thereof or changing its binding properties is described. In the procedure of this...
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5670315 |
Nucleic acid determination employing pyryilium dye
A PCR amplification product is detected, in quantitative determination of nucleic acid and measurement of the number of bacterial cells or specific genes, by addition of a dye compound which does...
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5665599 |
Chamber for cultivating cells
A multipart chamber for cultivating cells for observing long-term cell cultures. Extremely small distances can be achieved between the objective of the microscope and the planes inside the chamber...
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5661029 |
Biological culture growth and observation device
A biological culture growth and observation system provides for the growth of a biological sample in a growth medium, and the observation of the grown sample (organism) through a microscope...
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5658801 |
Medical test kit
A medical diagnostic test kit includes a rectangular flat bottom member having an external raised flange and an internal raised flange forming a cavity therein; an elongated dry chemistry membrane...
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5652149 |
Mixing apparatus & method for an optical agglutination assay device
An assay device for detecting the presence of analytes in an unknown sample includes a reaction system wherein resilient storage reservoirs containing reagents are fluidly connected to a track...
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5650125 |
Method and apparatus for conducting tests
The apparatus includes a receptacle member in the form of at least one row of receptacles for receiving cell samples, each having a closed end and an open end, and a holder adapted to receive the...
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5643742 |
System for electronically monitoring and recording cell cultures
This invention provides an improved system for monitoring and recording cell cultures. A method for measuring a delay period for an alternating current voltage applied across a pair of pins...
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5637469 |
Methods and apparatus for the detection of an analyte utilizing mesoscale flow systems
Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow...
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5635358 |
Fluid handling methods for use in mesoscale analytical devices
Disclosed are devices and methods for analyzing a fluid cell containing sample. The devices are composed of a solid substrate, microfabricated to define at least one sample inlet port and a...
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5627041 |
Disposable cartridge for an assay of a biological sample
A cartridge is provided to present a biological sample for analysis by an imaging instrument. The cartridge of the invention utilizes a series of channels, capillaries, reservoirs and stop...
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5624815 |
Method and apparatus for the analysis of biological material
A method for analyzing solid material in a liquid sample comprises the steps of: distributing the sample equally by passage through a number of discrete wells adapted to retain the solid material,...
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5620662 |
Temporary liquid storage cavities in a centrifuge tube lid
A centrifuge tube with temporary liquid storage cavities. The centrifuge tube has an upper opening and defines a specimen enclosure therein. The tube includes a lid for sealably covering the upper...
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5609828 |
Sample card
An improved sample card is provided. The improved card, typically used in biochemical analysis, achieves high sample well capacity and improved fluid flow, including by means of a plurality of...
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5604130 |
Releasable multiwell plate cover
A cover effective to releasably seal a multiwell container, such as a microtitration plate, is disclosed. The cover contains a pad, fashioned from a flexible polymer sheet, and a plurality of...
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5601141 |
High throughput thermal cycler
A batch thermal cycler for large numbers of biological or chemical samples uses n modules each in good thermal contact with the samples, but substantially isolated from one another, thermally and...
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5543327 |
Apparatus for conducting the cytotoxicity assays on tumor cells
A method and apparatus for assaying the sensitivity of biopsied tumor cells to chemotherapeutic agents using a predetermined amount of chemotherapeutic agent in an easily deliverable form is...
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5534227 |
Thermoform dish insert
An assembly and components therefor are disclosed for use in the field of cell and tissue culture. The assembly includes a base having one or more wells, and a cell culture insert which is...
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5514343 |
Microtitration system
A microtitration system comprises a plurality of well and a frame-like holder with apertures for receiving the wells. Each well has a bottom wall and a side wall extending upwardly therefrom so as...
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5508200 |
Method and apparatus for conducting multiple chemical assays
A system for high performance automated chemical analysis includes a video camera photometer with a computer-controlled interference filter wheel. A fluidics system delivers ultramicro sample and...
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5508005 |
Non-screeching laboratory article
A laboratory article, and in particular a cluster plate is provided including a plurality of wells supported by a structural framework including a peripheral wall. At locations in the structural...
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5506141 |
Apertured cell carrier
An apertured cell carrier defines first and second outer surfaces and comprises an ordered array of holes therethrough, the holes being in identifiable positions on the carrier and sized to contain...
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5503803 |
Miniaturized biological assembly
A miniaturized biological assembly provides a miniature capillary environment in which a liquid medium containing microscopic-size particulate material can be placed for study under a microscope....
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5489532 |
Automatic test apparatus for antimicrobial drugs
An automatic test apparatus for use in a test method to determine antimicrobial drugs. The test apparatus comprises a first aluminum, electrically heatable block with holes for the insertion of...
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5487872 |
Ultraviolet radiation transparent multi-assay plates
An ultraviolet radiation transparent multi-assay plate for ultraviolet absorption spectroscopy of ultraviolet absorbing liquids comprising a plurality of cylinders fixed in a frame each covered at...
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5470743 |
Transmembrane cell culture device
A removable cell culture insert support device is provided which allows the initial development of cell cultures on the bottom membrane surface of an inverted cell culture insert. Following...
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5468650 |
Class microfiber histamine assay device
A histamine diagnostic assay device is provided in which glass microfibers treated with a polar organic polymer are deposited onto a carrier and used to selectively bind histamine in a sample. The...
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5432086 |
Apparatus for the automatic monitoring of microorganism culture
Impedance measurements from an array of cells containing microorganisms whose growth or multiplication are to be measured in terms of the impedance, utilizes electrodes which can be introduced into...
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5424213 |
Method for testing the reactivity of cells with respect to products
The present invention relates to a method for testing the reactivity of living cells with respect to at least one product, comprising the formation of a strip on which cells are present,...
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5419278 |
Vapor equilibration tray for growing protein crystals
In accordance with the present invention, a vapor equilibrium apparatus for growing and screening suitable protein crystals is provided which consists of a plastic tray having a plurality of...
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