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7491552 |
Fluid based analysis of multiple analytes by a sensor array
A system for the rapid characterization of multi-analyte fluids, in one embodiment, includes a light source, a sensor array, and a detector. The sensor array is formed from a supporting member into...
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7488606 |
Collection device for lateral flow chromatography
A device for collecting oral liquids includes a lateral flow chromatography strip having a collection member. The collection member is separated from the remainder of the chromatography strip by a...
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7488607 |
Electronically readable microarray with electronic addressing function
Methods and apparatus for electronically addressing and interrogating microarrays are disclosed. The described microarrays include a plurality of features disposed on a substrate. Each of the...
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7485433 |
Determination and quantification of red blood cell populations in samples
The invention relates to the detection and determination of erythrocytopathies and hemoglobinopathies. The invention provides a method for distinguishing between subsets of red blood cells in a...
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7485424 |
Labeled nucleotide phosphate (NP) probes
The present invention is directed to a method of sequencing a target nucleic acid molecule having a plurality of bases. In its principle, the temporal order of base additions during the...
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7485471 |
Detection of enhanced multiplex signals by surface enhanced Raman spectroscopy
Various methods of using Raman-active or SERS-active probe constructs to detect analytes in biological samples, such as the nucleic acid and/or protein-containing analytes in a body fluid are...
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7482153 |
Nucleic acid detection cassette and nucleic acid detection device
A nucleic acid detection cassette includes a cassette body, a nucleic acid detection region disposed in the cassette body, a first channel disposed in the cassette body, a second channel disposed...
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7476548 |
Dry reagent strip configuration, composition and method for multiple analyte determination
An assay device, analytical instrument and assay method for determining the presence or amount of an analyte in a fluid is disclosed. The device is a one-step lateral flow dry reagent immunoassay...
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7476551 |
Diagnosing atherosclerosis risk by measuring carbamylated low density lipoprotein levels
The present invention provides a method of determining whether an individual is at risk for atherosclerosis, comprising the step of: measuring the level of carbamylated LDL in a sample obtained...
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7476504 |
Use of reversible extension terminator in nucleic acid sequencing
The present invention relates to the uses of reversible extension terminator in conjunction with optical confinements in nucleic acid sequencing. The apparatus and methods embodied in the present...
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7476533 |
Diagnostic devices for use in the assaying of biological fluids
Diagnostic in-vitro devices for use in the assaying of biological fluids are provided which include cover plates or backing strips which exhibit hydrophilic properties to assist in transport of the...
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7473547 |
Test piece, method of and apparatus for manufacturing the test piece and method of and system for reading the same
A test piece for use in biological analysis of a sample is formed of a strip-like substrate and numbers of known specific binding agents which are different from each other and are arranged in a...
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7473563 |
Environmental sampling and testing device
Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a...
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7473549 |
Target recognition element and biosensor including the same
The present invention provides a target recognizing element wherein a receptor is fixed to an inclusion complex containing a mediator. The target recognizing element includes a first host molecule...
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7473551 |
Nano-mechanic microsensors and methods for detecting target analytes
The present invention relates generally to methods and compositions for analyzing test samples containing target analytes including proteins and nucleic acids. The invention uses a surface acoustic...
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7470549 |
Measurement method using biosensor
It is an object of the present invention to provide a method for simultaneously carrying out the detection or measurement of a substance interacting with a physiologically active substance...
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7470534 |
Mutated AQP, method for detecting cancer using the same, DNA chip having oligonucleotides of said mutated AQP sequence
The present invention relates to mutation genes of the AQP(aquaporin), a method for detecting cancer using mutations and expressions of the AQP and a DNA chip possessing oligonucleotides of mutated...
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7470533 |
Impedance based devices and methods for use in assays
A device for detecting cells and/or molecules on an electrode surface is disclosed. The device detects cells and/or molecules through measurement of impedence changes resulting from the cells...
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7468271 |
Molecular characterization with carbon nanotube control
There is provided a first reservoir containing a liquid solution including a molecule to be characterized and a second reservoir for containing a liquid solution including a molecule that has been...
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7465578 |
Nucleic acid sequencing by Raman monitoring of uptake of precursors during molecular replication
The methods, compositions and apparatus disclosed herein are of use for nucleic acid sequence determination. The methods involve isolation of one or more nucleic acid template molecules and...
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7462326 |
Device for the detection of at least one ligand contained in a sample that is to be analyzed
Disclosed is a device for detecting at least one ligand contained in a sample that is to be analyzed. Said device comprises an optical waveguide, on the surface of which at least one...
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7462495 |
Methods and compositions for use in diagnosing and characterizing chronic immune disease
Methods are provided for diagnosing and/or characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to...
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7459304 |
Method for analysing macromolecules
The invention relates to a method for the analysis of macromolecules using a microarray on which a plurality of first at least partly different macromolecules are located in a known arrangement,...
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7459315 |
Miniaturized assembly and method of filling assembly
A miniaturized assembly is provided whereby a fluid sample can be divided into a plurality of sample portions in retaining wells and the sample fluid can be displaced from open ends of the wells...
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7459305 |
Ingestible gastrointestinal device
An ingestible device is provided. The ingestible device comprises a sink mechanism, for generating net influx of at least one constituent-of-interest present in a gastrointestinal tract of an...
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7455967 |
Device for analyzing chemical or biological samples
The present invention relates to a method, and to a corresponding device, for analyzing chemical or biological samples in which chemical or biological samples and/or targets (probes) are applied in...
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7456022 |
Solid support having ligand immobilized thereon by using photocleavable linker
The present invention provides a method of analyzing the interaction between a ligand and a target molecule, which uses a solid support wherein the ligand is immobilized via a linker cleavable by...
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7452712 |
Sample block apparatus and method of maintaining a microcard on a sample block
A thermal cycling device for thermally cycling samples of biological material contained in a microcard having a top and bottom surface. The thermal cycling device can include a sample block having...
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7452669 |
Micro PCR device, method of amplifying nucleic acid and method of measuring concentration of PCR product using the same
A micro PCR device comprising an amplification chamber is provided. The amplification chamber has an inner surface coated with a polycationic polymer or a polyanionic polymer and includes electrodes.
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7452713 |
Process for manufacturing a microfluidic device with buried channels
A process for manufacturing a microfluidic device, including the steps of: forming at least one channel in a semiconductor material body; forming a dielectric diaphragm above the channel, for...
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7449343 |
Method for measuring surface plasmon resonance
It is an object of the present invention to provide a measurement method which can suppress noise when a specific binding reaction between a physiologically active substance and a test substance is...
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7449329 |
Blood test kit
A blood crossmatching apparatus, kit and methods for testing the compatibility of mammals for blood transfusion. Particulate layers in the apparatus allow nonagglutinated red blood cells to...
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7449328 |
Probe matrix-based device for identifying microorganisms
Device for identifying microbial organisms using a collection of polynucleotide probes, each probe having binding specificity for the ribosomal nucleic acids of at least one microbe. The collection...
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7445941 |
Diagnostic devices and apparatus for the controlled movement of reagents without membranes
The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of...
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7445938 |
System and method for detecting presence of analytes using gratings
The present invention is directed to an optical grating sensor configured to detect a phase change in light passing though the system due to a binding event caused by an analyte. The grating sensor...
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7442499 |
Substrates comprising polynucleotide microarrays
A method of determining the relative amounts of individual polynucleotides in a complex mixture of different-sequence polynucleotides is disclosed. The polynucleotides, after fluorescent labeling,...
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7444005 |
Apparatus and method for using optical mouse engine to determine speed, direction, position of scanned device and to obtain quantitative or qualitative data from same
A test strip reader is provided with an optical mouse integrated circuit sensor that reads the test line, reference line and control line of a lateral flow assay strip by light absorption and...
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7442502 |
Biochip
When the genetic analysis is performed by using a DNA microarray, the inspection accuracy is improved. A sample solution is supplied onto a base plate to prepare the DNA microarray comprising a...
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7439079 |
Assay devices having detection capabilities within the hook effect region
A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether...
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7438856 |
Microfluidic devices and methods
Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom...
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7439055 |
Biomolecular detection device
A device for detecting and measuring the concentration of biomolecules in solution, utilizing a conducting electrode in contact with a solution containing target biomolecules, with a film with...
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7435575 |
Method for processing a nucleic acid sample by oscillating a cartridge, a system and a cartridge for performing such a method
A method for processing a nucleic acid sample contained in a liquid comprises: (a) introducing the liquid into a chamber ( 11 ) of a cartridge ( 12 ) which contains a chip shaped carrier ( 14 ), an...
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7435579 |
Biosensor and related method
A microscale biosensor for use in the detection of target biological substances includes a detection chamber disposed on the substrate and defining a volume between 1 pico-liter and 1 micro-liter....
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7432111 |
Non-continuous immunoassay device and immunoassay method using the same
A non-continuous immunoassay device which includes two or more separated pads for immunoassay analysis, and is capable of controlling the migration speed of a mobile phase between the separated...
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7433552 |
Obtaining analyte information
Light, such as from an analyte-wavelength converter or other optical sensor, is propagated to a detector or transmission structure with an entry surface and with output positions such as in an exit...
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7429492 |
Multiwell plates with integrated biosensors and membranes
The invention provides compositions and methods of detecting binding of molecules to a biosensor. Compositions of the invention comprise a multiwell plate with an integrated biosensor and a membrane.
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7427512 |
Light-controlled electrokinetic assembly of particles near surfaces
A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution....
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7428200 |
Method for triggering through disc grooves and related optical analysis discs and system
An optical analysis disc includes grooves defining corresponding laser-readable tracks and trigger marks that identify respective target regions on the disc. The trigger marks are implemented as a...
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7425455 |
Biosensor, magnetic molecule measurement device
A biosensor not requiring washing of an unbonded label molecular by analyzing an object to be measured such as an antigen, an antibody, a DNA, and an RNA through magnetic field sensing. The...
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7425421 |
Method for the enumeration of micronucleated erythrocyte populations while distinguishing platelets and/or platelet-associated aggregates
A method for the enumeration of micronucleated erythrocyte populations while distinguishing platelet and platelet-associated aggregates involves the use of a first fluorescent labeled antibody...
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