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7390676 |
System and method for programmable illumination pattern generation
A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution....
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7390674 |
Lateral flow devices using reactive chemistry
There is provided a lateral flow assay device for detecting the presence or quantity of an analyte residing in a test sample where the lateral flow assay device has a porous membrane in...
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7390650 |
System and method for obtaining and maintaining high-resistance seals in patch clamp recordings
The invention provides a system, system components, and a method for rapidly obtaining and stably maintaining a cell in optimal contact with the cell-contacting surface of a sensor in a cell-based...
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7390649 |
Sensor chips with multiple layers of polysiloxane
The invention relates to sensor chips with multiple layers of polysiloxane with improve homogeneity.
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7387892 |
Biosensor using microdisk laser
A compact sensor for detecting the presence of biological or chemical species includes a microdisk laser and a wavelength shift detector. The microdisk laser is coated with a biological or chemical...
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7387889 |
Measurement of concentrations and binding energetics
Free-standing microfluidic channels are used to both transport and analyze molecules of interest. In a biochemical context, such molecules may be polypeptides, nucleic acids, or other biomolecules....
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7387715 |
Sample positioning and analysis system
Systems for positioning and/or analyzing samples such as cells, vesicles, cellular organelles, and fragments, derivatives, and mixtures thereof, for electrical and/or optical analysis, especially...
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7384797 |
Resonant optical cavities for high-sensitivity high-throughput biological sensors and methods
Biosensors including resonant optical cavities. The resonant optical cavities are shaped so as to generate whispering gallery modes, which increase the quality factors of the cavities and...
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7384796 |
Assays
An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also...
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7384794 |
Micro-devices and analytical procedures for investigation of biological systems
Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the...
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7384793 |
Biological measurement system
In a biological measurement system ( 10 ) for collecting one or more samples of sputum and/or mucus from a patient in the form of an aerosol and for analyzing said one or more samples to detect...
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7384779 |
Porous substrate plates and the use thereof
A substrate plate or device adapted for use with biological or chemical assays is disclosed. The device may take the form of a multi-well plate having a three-dimensional, porous layer as part of a...
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7384778 |
Methods and devices for the detection of pathogenic microorganisms and their antimicrobial susceptibility
The present invention provides devices and methods for determining the presence or absence of pathogens in a biological sample and for the concurrent determination of the antimicrobial...
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7381375 |
Assay systems with adjustable fluid communication
Systems, including apparatus and methods, for performing assays with adjustable fluid communication between samples.
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7381374 |
Immunoassay devices and methods of using same
An immunoassay cartridge for sensing at least one analyte in a biological sample is disclosed. The immunoassay cartridge comprises a supporting plate, a reaction cavity made within the supporting...
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7381315 |
Multi-channel analyte-separation device employing side-entry excitation
A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to...
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7378285 |
Devices for the detection of multiple analytes in a sample
The present invention relates generally to an assay for detecting and differentiating multiple analytes, if present, in a single fluid sample, including devices and methods therefore.
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7371585 |
Membranes incorporating recognition moieties
The present invention provides a thiosulfonate-activated ionophore comprising an ionophore, a spacer group, and an alkylthiosulfonate moiety. A preferred ionophore is gramicidin A. A preferred...
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7371562 |
Guided mode resonant filter biosensor using a linear grating surface structure
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
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7371348 |
Multiple array format
A multiple array substrate having multiple assay chambers, each assay chamber containing one or more arrays. The assay chambers include a form-in-place gasket between a substrate and a cover....
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7368280 |
Detection of biospecific interactions using amplified differential time domain spectroscopy signal
A method for detecting specific associations between a tethered molecule and an untethered target molecule. The method comprises (1) selecting a tethered molecule; (2) alternately impinging THz...
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7364898 |
Customized micro-array construction and its use for target molecule detection
The present invention relates to a detection and quantification method of different sets of target molecules ( 1, 3 ), being possibly present simultaneously in a biological sample by the use of a...
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7364896 |
Test strips including flexible array substrates and method of hybridization
Individual and aggregate test strip arrays having a backing strip supporting a flexible array substrate which supports an addressable collection of probes are taught. Hybridization cells for use...
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7364696 |
Methods and devices for droplet microchromatography
Disclosed devices and methods for droplet microchromatograhy are aimed at optical monitoring and rapid analysis of a drying droplet. The device includes droplet deposition component preferably made...
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7364657 |
Integrated system for on-site cell acquisition, processing, and delivery
Numerous embodiments of a system and method for treating cardiac tissue are described. In one embodiment, bone marrow cells are extracted from a patient. The cells are then processed to isolate...
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7361500 |
Apparatus and method for electrically contacting biological cells suspended in a liquid
An apparatus for electrically contacting biological cells suspended in a liquid has a substrate having at least one opening and an electrode for electrically contacting a cell immobilized above the...
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7358079 |
Flow cell array and the utilization thereof for multianalyte determination
A one- or two-dimensional arrangement of flow cells is provided, as part of an array of sample compartments, with at least one inlet and outlet for each sample compartment, formed by a base plate...
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7354614 |
Diagnostic device
A diagnostic device 1 for performing an immunochromatographic analysis of a sample is disclosed. The diagnostic device 1 comprises a porous substrate 10 for performing the analysis and a...
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7351591 |
Surface modification of metals for biomolecule detection using surface enhanced Raman scattering (SERS)
The present invention is based on the discovery that the methods described herein for the production of metallic colloids result in colloids exhibiting increased signal enhancement and...
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7351590 |
Methods and compositions for directed microwave chemistry
The present invention concerns a novel means by which specific chosen reactions can be accelerated through the use of a new type of artificial enzyme. The invention allows specific reactions to...
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7351575 |
Methods for processing biological materials using peelable and resealable devices
Devices and methods for performing assays on materials, particularly biological materials, are provided. The devices and methods make use of self-sealing members, which can be applied to a flat...
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7351379 |
Fluid containment structure
A fluid containment structure that includes a substrate with a gasket surface and a form-in-place gasket disposed on the gasket surface and a method for forming the fluid containment structure are...
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RE40209 |
Cell potential measurement apparatus having a plurality of microelectrodes
A cell potential measurement apparatus, which uses a planar electrode enabling a multi-point simultaneous measurement of potential change arising from cell activities, is provided which can conduct...
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7348182 |
Directed microwave chemistry
The present invention concerns a novel means by which chemical preparations can be made. Reactions can be accelerated on special chips using microwave energy. The chips contain materials that...
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7344893 |
Immuno-gold lateral flow assay
A chromatographic lateral-flow assay system for rapid, high sensitivity method of detecting low levels of ligands in body fluids, with few false positives and few false negatives. The lateral-flow...
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7341873 |
Method for determination of platelets quality
There is provided a method for assessing the quality of platelet concentrates for determining their suitability for transfusion. More specifically dynamic light scattering measurements of the...
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7338811 |
Integrated circuit chip for bioassays
The invention is directed to novel IC chips containing substances used particularly in bioassays. Furthermore, the invention is directed to assay methods and kits using these chips.
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7335514 |
Optical biosensor
The present invention relates to an optical biosensor comprising a porous matrix. In the specific case, reference is made to anodized porous alumina, on the surface of which the biological...
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7335286 |
Immersion sensor for measuring the concentration of an analyte with the help of an oxidase
The invention relates to measuring the concentration of analytes with the aid of an oxidase in an immersion sensor situated in a fluid or in a matrix containing fluid. Oxygen diffuses into the...
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7332274 |
Process of quality examining for microarray of biological material
The present invention relates a process of quality examining for microarray of biological material. More particularly, the present invention is directed to a process of quality examining for...
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7329536 |
Piezoimmunosensor
An apparatus comprising one or more piezoelectric mass sensors for use in diagnostic and analytic processes, in particular for immunochemical detection of diagnostically relevant analytes in real...
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7329535 |
Apparatus for circulating carrier fluid
Provided are an apparatus for circulating a carrier fluid having two or more chambers or sections, an apparatus for amplifying a nucleic acid using the same, and a chip containing the same. The...
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7329534 |
Buffy coat tube and float system and method
A tube and float system for use in separation and axial expansion of the buffy coat is provided. The system includes a transparent, or semi-transparent, flexible sample tube and a rigid separator...
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7329533 |
Unit for the treatment of histological samples
The invention relates to a unit for the treatment of histological samples. The unit comprises a treatment chamber ( 1 ), a device ( 2 ) for supplying and removing treatment agents ( 3, 3′, 3 ″)...
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7326776 |
Preparation and use of mixed mode solid substrates for chromatography adsorbents and biochip arrays
For certain mixed mode resins having anionic character, a ligand is joined to a solid support via a linkage that includes a mercapto-, ether- or amino-containing moiety. A suitable ligand comprises...
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7326578 |
Urine assay for ovarian reserve
It has been found that a urine test for ovarian reserve can be provided which is equivalent in sensitivity to current laboratory methods which determine ovarian reserve based on FSH levels in...
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7323140 |
Moving microdroplets in a microfluidic device
The present invention relates to a system and method for moving samples, such as fluid, within a microfluidic system using a plurality of gas actuators for applying pressure at different locations...
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7320775 |
Exchangeable flow cell assembly with a suspended capillary
There is provided a flow cell assembly in which a shuttle supports and positions a capillary with its end extending beyond the shuttle. The flow cell assembly facilitates the replacement of a flow...
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7315784 |
Network for evaluating data obtained in a biochip measurement device
In a method and a network for evaluating medical data in a clinical study, biochips containing patient samples with multiple biomolecular markers are tested in a number of point of care test...
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7314749 |
Method and apparatus for assay based on light diffraction
The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears...
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