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7166458 |
Assay and method for analyte sensing by detecting efficiency of radiation conversion
In one aspect, the present invention is a system, a device and a method for sensing the concentration of an analyte in a fluid or matrix. The analyte may be glucose or any other chemical of...
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7160689 |
Pretreatment instrument of saliva and pretreatment method of saliva
In a pretreatment instrument and a pretreatment method of saliva, used for identification and quantitation of Streptococcus mutans in saliva by the immunochromatographic method utilizing an...
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7160730 |
Method and apparatus for cell sorting
A cell sorter system that includes a precision pump that causes fluid containing cells to enter an inlet port where the fluid is exposed to source light of one or more wavelengths and where cells...
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7157234 |
Detection of very low quantities of analyte bound to a solid phase
A microscale binding assay, analyte binding array, and kits are disclosed, which exploit the mass action law to harvest analyte from a liquid sample. This is achieved by fabrication of sorbent...
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7157049 |
Optical bio-discs and fluidic circuits for analysis of cells and methods relating thereto
The present invention is directed to optical bio-discs, methods, and optical disc drives for clinical diagnostics. The present invention is further directed to methods for determining the quantity...
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7157050 |
System and method for detecting biological and chemical material
A system and method are provided for detecting biological and chemical material. To measure biological materials such as genes easily at low costs, the device for implementing a small-sized, high...
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7153681 |
Assay reagents and devices
A reagent useful in immunoassays, comprising a direct particulate level co-sensitised with a specific binding agent having specificity for an analyte or analyte analogue and with a non-specific...
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7153682 |
Microarrays on mirrored substrates for performing proteomic analyses
Provided are peptidomimetic protein-binding arrays, their manufacture, use, and application. The protein-binding array elements of the invention include a peptidomimetic segment linked to a solid...
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7153475 |
Aerosol particle analyzer for measuring the amount of analyte in airborne particles
Aerosol particle analyzer (APA) for measuring the amount of analyte in airborne particle is described. The APA uses an analysis liquid. In most embodiments, this analysis liquid is chosen so that...
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7148056 |
Diagnostic devices containing porous material
Diagnostic devices are disclosed which contain porous material. The porous material preferably comprises silica and alumina. Chemical and/or biological molecules can be bound to the porous material...
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7148058 |
Protein microarrays on mirrored surfaces for performing proteomic analyses
Provided are protein microarrays, their manufacture, use, and application. Protein microarrays in accordance with the present invention are useful in a variety preoteomic analyses. Various protein...
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7144742 |
Quantitative lateral flow assays and devices
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention...
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7141414 |
Biosensor
The illustrated embodiment comprises a biosensor utilizing plant cells and nutrient media for maintaining the plant cells in a live condition. A light source having desired optical characteristics...
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7141416 |
Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
The present invention relates to optical bio-disc systems and related methods and to immobilizing receptor molecules. When a sample is injected into a fluidic circuit, the target agent binds to a...
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7141415 |
Method for the controlled transport of magnetic beads and device for executing said method
The present invention is related to a method and corresponding devices for controlled transport of magnetic beads between a position X and different position Y, such that the magnetic beads are...
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7138269 |
Microflow system for particle separation and analysis
A micro flow system is provided for separating particles, comprising a microfabricated member having a flow channel ( 5 ) defined therein for guiding a flow of a fluid containing the particles...
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7135325 |
Short enzyme donor fragment
Short enzyme donor fragments of β-galactosidase are provided of not more than 40 amino acids, where the short fragments are used as a label and may be substituted with a wide variety of organic...
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7132275 |
Multifunctional magnetic nanowires
The invention provides multisegmented, multifunctional magnetic nanowires for the probing and manipulation of molecules at the cellular and subcellular level. The different segments of the nanowire...
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7132242 |
Method and device for targeted delivery of materials to selected single cells
A method and device for delivering a quantity of at least one material to a selected single cell in a manner that permits impingement of material with the cell. The material travels at a suitable...
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7129081 |
Apparatus and method for detecting microorganisms
The present invention relates to the fast detection of microorganisms, i.e. of bacteria, fungi, cells and other organisms, making use of methods and apparatuses coming from nanotechnology....
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7125711 |
Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
A microliter liquid sample, particularly a biological sample, is analyzed in a device employing centrifugal and capillary forces. The sample is moved by capillary forces into one or more metering...
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7122378 |
Carriers having biological substance
By the present invention, there is provided a fiber having nucleic acid immobilized thereon, an alignment of fibers having nucleic acid immobilized thereon, and a slice thereof.
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7118907 |
Single molecule detection systems and methods
A microfluidic system is provided that includes a substrate, a first microchannel disposed in the substrate for providing a reactant to a reaction zone, a second microchannel disposed in the...
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7118923 |
Nanoporous membrane immunosensor
A sensor for a selected analyte in a test sample has (a) a semipermeable membrane with pores for retaining the analyte, where the membrane has been chemically modified by attachment of membrane...
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7118922 |
System and method for immunosensor regeneration
The present invention allows for regeneration of any chemical and biological sensor systems without totally destroying the primary antibodies in the system. The present invention provides...
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7115362 |
Electrochemical test device and related methods
An electrochemical test device is provided for determining the presence or concentration of an analyte in an aqueous fluid sample. The electrochemical test device includes a working electrode and a...
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7115229 |
Apparatus and method for monitoring molecular species within a medium
Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing....
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7112451 |
Biosensor
A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an...
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7112453 |
Retentate chromatography and protein chip arrays with applications in biology and medicine
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
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7112452 |
Method and sensor for detecting the binding of biomolecules by shear stress measurement
A method and sensor are provided for detecting the binding of a probe and a target biomolecule by measuring a difference in the shear stress on the surface of the sensor before and after...
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7109042 |
Assays
An analytical test device useful for example in pregnancy testing, comprises a hollow casing ( 500 ) constructed of moisture-impervious solid material, such as plastics materials, containing a dry...
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7105339 |
Retentate chromatography and protein chip arrays with applications in biology and medicine
This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity...
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7098040 |
Self-contained swab-based diagnostic systems
A diagnostic test unit is provided. The test unit comprises a stem having a first end and a second end, the stem defining at least one flow channel extending between the first end and the second...
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7097973 |
Method for monitoring molecular species within a medium
Apparatus and methods for monitoring, analyzing, and/or discriminating molecular species, preferably a biomolecule, within a medium using a multisensor array (MSA) and multivariate processing....
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7097976 |
Methods of analysis of allelic imbalance
Methods are provided for identification of genes that are imprinted. In another embodiment methods are provided for identification and analysis of genes whose expression shows allelic imbalance....
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7097981 |
Reaction wells, assembly thereof, immunoassay apparatus and method using such well assemblies
The present invention relates mainly to reaction vessels, to sets of such vessels for automatic immunological assay apparatuses, to automatic immunological assay apparatuses making use of such sets...
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7098041 |
Methods to view and analyze the results from diffraction-based diagnostics
An analyzer useful in determining the presence of an analyte using a diffraction based sensing device and methods and systems using this device. The present invention may be used with a variety of...
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7090988 |
Optoelectronic sensor
A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where...
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7090992 |
Bioluminescent bioreporter integrated circuit devices and methods for detecting estrogen
Bioelectronic devices for the detection of estrogen include a collection of eukaryotic cells which harbor a recombinant lux gene from a high temperature microorganism wherein the gene is operably...
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7090984 |
Device and method for detecting substance
A method for detecting a substance, comprising developing a developing liquid through a test region up to a reference region, and a detection device for use therein, wherein the reference region...
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7087203 |
Methods and apparatus for blood typing with optical bio-disc
This invention relates to clinical diagnostic assays and related optical bio-discs and a disc-reading apparatus. The invention is directed to a method for determining the blood cell type of an...
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7083985 |
Coplanar waveguide biosensor for detecting molecular or cellular events
A coplanar waveguide biosensor and methods of use include a coplanar waveguide transmission line and a sample containment structure. The coplanar waveguide transmission line is operable to support...
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7081227 |
Amphiphilic mediated sample preparation for micro-flow cytometry
A flow cytometer includes a flow cell for detecting the sample, an oil phase in the flow cell, a water phase in the flow cell, an oil-water interface between the oil phase and the water phase, a...
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7081353 |
Drug susceptibility measurement method and apparatus thereof
A method and apparatus wherein measurement current values output from a first oxygen sensor and a second oxygen sensor are time sequentially measured. Each moving average value is calculated from...
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7074610 |
System and method of microdispensing and arrays of biolayers provided by same
An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present...
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7075428 |
Methodology and apparatus for the detection of biological substances
A methodology and an apparatus for the detection of biological substances employing the integration of multiple functions and units designed into and implemented in the form of an individual...
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7070987 |
Guided mode resonant filter biosensor using a linear grating surface structure
Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also...
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7071005 |
Method and device for concentrating selected groups of microorganisms
A method and device are described to concentrate target organisms from a mixture of organisms. Beads ( 1 ) made of material such as nylon, polystyrene or glass are coated with antibodies of...
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7070927 |
Methods and compositions for efficient nucleic acid sequencing
Disclosed are novel methods and compositions for rapid and highly efficient nucleic acid sequencing based upon hybridization with two sets of small oligonucleotide probes of known sequences....
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7070920 |
Screening arrangment for screening immunoassay tests and agglutination tests
A screening device for performing an immunoassay test to detect the presence of a compound in a body fluid. The device includes a holder for removably receiving a membrane to which the fluid has...
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