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7592139 |
High temperature flow-through device for rapid solubilization and analysis
Devices and methods for thermally lysing of biological material, for example vegetative bacterial cells and bacterial spores, are provided. Hot solution methods for solubilizing bacterial spores...
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7585682 |
Magnetic in situ dilution
The invention involves methods, assays, and components for the detection and analysis of binding between biological or chemical species, and can specifically be used for drug discovery. In an...
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7582471 |
Biosensor for the detection of protein kinase A, and kit comprising the same
The present invention relates to a biosensor specifically detecting a protein kinase A (PKA), and a diagnosis kit comprising the biosensor. In particular, the present invention relates to a...
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7582420 |
Multiplex nucleic acid reactions
The invention is directed to a variety of multiplexing methods used to amplify and/or genotype a variety of samples simultaneously.
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7582470 |
Device for amplifying and detecting a target nucleic acid
Compositions, methods and devices for detecting nucleic acids. The invention particularly regards composite arrays of immobilized amplification primers and hybridization probes. Also disclosed are...
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7582415 |
Rapid detection of replicating cells
The invention enables efficient, rapid, and sensitive enumeration of living cells by detecting microscopic colonies derived from in situ cell division using large area imaging. Microbial...
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7582259 |
Blood analysis device and blood analysis method
A blood analysis device for centrifugally separating plasma in a channel, wherein conveyance of blood, plasma and calibration liquid is effected within the device without using a pump or the like....
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7579184 |
Methods to increase dynamic range and improve quantitative analysis in rapid biosensors
Conductimetric assay devices that have both low end and high end sensitivity are described. The geometric shape and/or arrangement of the capture zones make it possible for the assay devices to...
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7579823 |
Thin film sensor
An electrically operated, particle detecting, or characterizing, sensor structured as a thin film multilayer sandwich. Three or more electrodes are deposited onto thin layers of film, and stacked...
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7575915 |
Biosensor
A biosensor is provided with a development layer for developing an inspection target solution, that has a reagent immobilization part where an antibody for a measurement target in the inspection...
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7572644 |
Hydrogel copolymer, substrate coated with the copolymer, method of producing microarray using the copolymer, and microarray produced by the method
A novel hydrogel copolymer, a substrate coated with the copolymer, a method of producing a microarray using the copolymer, and a microarray produced by the method are provided. The use of the...
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7569397 |
Immunoassay devices and use thereof
An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site...
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7569381 |
Biochemical reaction cassette with improved liquid filling performance
A biochemical reaction cassette comprises a housing member, a reaction chamber arranged in the housing member and having a bottom section and a ceiling facing the bottom section, an injection port...
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7569812 |
Remote reagent ion generator
An improved ion source and means for collecting and focusing dispersed gas-phase ions from a remote reagent chemical ionization source (R2CIS) at atmospheric or intermediate pressure is described....
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7566418 |
Biochemical concentrator and drug discovery
A novel label-free sensitive detection method by employing a novel sensitive charge sensor is provided. Dissociation constant information is provided by a simple measurement of the dissociation of...
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7566564 |
Signal amplification using a synthetic zymogen
Described herein are zymogens, methods of use for zymogens, and devices that incorporate zymogens. The zymogens include a substrate and an enzyme. The substrate can inhibit the enzyme and is a...
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7563615 |
Apparatus and method for automated monitoring of airborne bacterial spores
An apparatus and method for automated monitoring of airborne bacterial spores. The apparatus is provided with an air sampler, a surface for capturing airborne spores, a thermal lysis unit to...
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7565273 |
Determination of the age, identification and sealing of a product containing volatile components
The invention concerns a method and system for determining the age of an object such as a product containing volatile components, comprising: measuring a first strength of a first scent with a...
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7560258 |
Glass-immobilized, protein-acrylamide copolymer and method of making thereof
Disclosed are a polyacrylamide-based method of fabricating surface-bound peptide and protein arrays, the arrays themselves, and a method of using the arrays to detect proteins and to measure their...
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7556769 |
Fecal occult test packaging
A specimen testing device having a folding top having a top inside and a top outside; a back portion having at least one flap opening, the back portion in folding communication with the folding...
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7556778 |
Fluid handling apparatus and fluid handling unit for use therein
A fluid handling apparatus 10 includes a plurality of fluid handling subassemblies 16 , each of which is mounted in a corresponding one of mounting recessed portions 14 of a plate body 12 ....
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7556933 |
Reagent system and process for adenosine triphosphate monitoring
A reagent system comprises a first reagent which includes a high pH phosphate buffer, and a second reagent which includes luciferase, luciferin, a magnesium salt and an enzyme stabilizer. The...
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7556962 |
Saccharide composition purification instrument
The present invention provides a sugar chain purification instrument which can continuously and efficiently purify the sugar chain. According to the present invention, the instrument includes an...
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7553633 |
Apparatus and method for detecting live cells with an integrated filter and growth detection device
A device for rapid concentration and detection of live cells in fluids includes a filter to capture a cell sample. The filter includes a first physical barrier with apertures of a first size and a...
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7550287 |
Cell culture system apparatus for checking cultured cells and apparatus for culturing cells
The present invention discloses a cell culturing system that cultures predetermined cells collected from a patient and supplies cultured cells to the original patient, which together with enabling...
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7547557 |
Directed-flow assay device
A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one...
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7547554 |
Method and device for the detection of very small quantities of particles
The invention relates to a method and a device for detecting very small quantities of particles. The inventive method is based on a detection of antigen-antibody reaction products and provides a...
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7544507 |
Microfluidic chip for high-throughput screening and high-throughput assay
Disclosed is a micro-fluidic chip for high-throughput screening and high-throughput assay, in which its structure is improved, thereby enhancing the efficiency of high-throughput screening and...
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7544503 |
Apparatus for the pH determination of blood and method therefor
The present invention relates to a spectroscopic apparatus for non-invasive in vivo analysis of blood and to a corresponding analysis method, in particular for direct determination of the pH value...
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7541167 |
Porous glass composite material
A porous glass composite material comprising at least one alkoxodisilane (precursor) having the general formula (or 1 ) 3 Si-spacer-Si(OR 2 ) 3 ,wherein R 1 and R 2 are the same or different and...
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7541194 |
Device for collection and assay of oral fluids
A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend...
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7537937 |
Lateral flow assay device
A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow...
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7537934 |
Chemiluminescence sensor array
Embodiments of the invention relate to integrated chemiluminescence devices and methods for monitoring molecular binding utilizing these devices and methods. These devices and methods can be used,...
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7534578 |
Self-referencing biodetection method and patterned bioassays
The invention relates to compositions and methods for detecting biomolecular interactions. The detection can occur without the use of labels and can be done in a high-throughput manner. The...
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7534576 |
Method and a device for the evaluation of biopolymer fitness
A Method for identifying one or a small number of molecules, especially in a dilution of ≦1 μM, using laser excited FCS with measuring times ≦500 ms and short diffusion paths of the molecules...
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7532779 |
Single mode (SM) fiber optical reader system and method for interrogating resonant waveguide-grating sensor(s)
An optical reader system is described herein which has a single mode (SM) optical fiber launch/receive system that uses one or more SM optical fibers to interrogate a biosensor and does not use...
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7531726 |
Controlled alignment of nanobarcodes encoding specific information for scanning probe microscopy (SPM) reading
The methods, apparatus and compositions disclosed herein concern the detection, identification and/or sequencing of biomolecules, such as nucleic acids or proteins. In certain embodiments of the...
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7527765 |
Consumer food testing device
A food testing device for testing for the presence of harmful contaminants in a food sample, includes a vessel adapted for holding a liquefied food sample, a liquefier operatively associated with...
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7528952 |
Hand-held fluorescence polarimeter
A small, portable, hand-sized apparatus for detecting microorganisms or chemicals in liquid samples by fluorescence polarization. The apparatus operates using a low power excitation light source,...
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7527981 |
Bioweapon-detecting fibrous-network products and methods for making same
Methods are disclosed for producing a bioweapon-sensitive fibrous-network product, wherein the subject products exhibit a color change in response to exposure to a biological agent (or portion...
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7524670 |
Protocol and apparatus for determining heparin-induced thrombocytopenia
A hemostasis analyzer, such as the Thrombelastograph® (TEG®) hemostasis analyzer is utilized to measure continuously in real time, the hemostasis process from the initial fibrin formation,...
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7524671 |
Handheld raman blood analyzer
Methods and apparatus for in vitro detection of an analyte in a blood sample using low resolution Raman spectroscopy are disclosed. The blood analyzer includes a disposable strip for receiving a...
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7524464 |
Smart disposable plastic lab-on-a-chip for point-of-care testing
Disclosed herein is a fully-integrated, disposable biochip for point-of-care testing of clinically relevant parameters. Specifically, in accordance with an embodiment of the present invention, the...
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7521226 |
One-step enzymatic and amine detection technique
A technique for detecting the presence or quantity of an enzyme (or enzyme inhibitor) and/or an amine within a test sample is provided. For example, in one embodiment, a diagnostic test kit is...
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7521019 |
Sensor device and methods for manufacture
The present invention provides a device and methods for detecting the presence of an analyte in a sample using an encapsulated sensor. Methods for manufacturing the sensor are also disclosed.
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7521225 |
Nanotube structures having a surfactant bilayer inner wall coating
Nanotubes and nanotube array structures comprise (a) a nanotube having an inner wall portion; and (b) a bilayer coating formed on the inner wall portions, with the bilayer coating comprised of...
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7517660 |
Optoelectronic sensor
A device for detecting the presence of an antigen including (1) a cell having antibodies which are expressed on the surface of the cell and are specific for the antigen to be detected, where...
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7517656 |
Optical sensor and methods for measuring molecular binding interactions
Methods and devices for the measurement of molecular binding interactions. Preferred embodiments provide real-time measurements of kinetic binding and disassociation of molecules including binding...
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7514938 |
Dielectric relaxation spectroscopy apparatus and methods of use
Methods and apparatus for measuring the dielectric relaxation properties of a sample are disclosed. Methods are disclosed for amplifying or controlling the dielectric relaxation properties of a...
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7514255 |
Methods and devices for detecting pancreatic lipase
A method and device for determining pancreatic lipase in an animal blood sample. In one aspect, the device includes a compartmentalized container for storing and reacting the reagents for use in...
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