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8529837 System and method for detecting specific binding reactions using magnetic labels  
A system and method for detecting specific binding reactions using magnetic labels.
8530230 Multiplexed assay methods  
The present invention is directed to methods for conducting multiplexed assays. The methods are particularly well suited for measuring a plurality of analytes that may be present in very different...
8530185 Methods and devices for microencapsulation of cells  
Devices for the microencapsulation of cells include a first chamber for containing a cell-solution suspension. A plate covers one end of the first chamber. The plate has a plurality of apertures....
8524504 Sensor  
This invention relates to a method for detecting an analyte in a sample, comprising the steps of exposing the sample to a transducer which is capable of transducing a change in energy to an...
8524450 Microvessels, microparticles, and methods of manufacturing and using the same  
A method of reading a plurality of encoded microvessels used in an assay for biological or chemical analysis. The method can include providing a plurality of encoded microvessels. The microvessels...
8524487 One-transistor pixel array with cascoded column circuit  
To reduce the pixel size to the smallest dimensions and simplest form of operation, a pixel may be formed by using only one ion sensitive field-effect transistor (ISFET). This one-transistor, or...
8524489 Particle or cell analyzer and method  
A particle analyzer in which tagged particles to be analyzed are drawn through a suspended capillary tube where a predetermined volume in the capillary tube is illuminated. The illumination...
8518342 Integrated analysis device which can be fitted to a container housing a sample to be analyzed  
The present invention relates generally to the field of analysis, for example biological analysis. More specifically, the present invention relates to an analysis device (10, 40, 501, 60) designed...
8513014 Method for fabricating foam scaffolds to culture cells  
Methods and apparatuses for using microfluidics to generate bubbles and using the generated bubbles to construct scaffolds and cell-holding structures for culturing biological samples or analytes....
8512946 Composite particles  
Composite particles and methods of synthesizing a composite particle are disclosed, in particular, methods of synthesizing a composite particle comprising a dielectric component, a magnetic...
8513001 Method and apparatus for target detection using electrode-bound viruses  
A biosensor capable of detecting the presence and/or concentration of an analyte or biomarker includes at least one electrically conductive electrode operatively coupled to an impedance analyzer...
8512947 Detection of nucleic acids using a cantilever sensor  
Detection of miniscule amounts of nucleic acid is accomplished via binding of target nucleic acid to probe material, composed of nucleic acid, which is bound to a sensor configured to sense mass....
8506887 Porous membrane waveguide sensors and sensing systems therefrom for detecting biological or chemical targets  
A sensor for sensing at least one biological target or chemical target is provided. The sensor includes a membrane includes a membrane material that supports generation and propagation of at least...
8507258 Apparatus for perforating membrane  
A method of perforating a membrane and an apparatus therefor is presented. The method includes bringing a membrane-denaturing substance into contact with or close proximity to at least a site of...
8507253 Photobioreactor cell culture systems, methods for preconditioning photosynthetic organisms, and cultures of photosynthetic organisms produced thereby  
Certain embodiments of the invention involve methods and systems for preselecting, adapting, and preconditioning one or more species of photosynthetic organisms, such as algae, to specific...
8507257 Combined thermal devices for thermal cycling  
The invention relates to systems and methods including a combination of thermal generating device technologies to achieve more efficiency and accuracy in PCR temperature cycling of nucleic samples...
8501406 Selectively functionalized arrays  
Methods, substrates, and devices related to arrays of optical confinements having surfaces with high levels of bias. Substrates having transparent or silica based portions and opaque or reflective...
8497135 Diagnostic kits to detect SP22 and SP22 antibodies  
Oral, topical and injectable contraceptives, which are based on sperm protein 22 kDa (SP22) polypeptides and antibodies and infertility diagnostics and kits are provided.
8491851 System and method for enabling and disabling a portable assay reader device  
A detection system in a portable assay reader device is enabled or activated after a user applies a manual force to a portion of the reader device, to an object supporting the assay test strip, or...
8492085 Method of designing addressable array suitable for detection of nucleic acid sequence differences using ligase detection reaction  
The present invention is directed to a method of designing a plurality of capture oligonucleotide probes for use on a support to which complementary oligonucleotide probes will hybridize with...
8491561 Micromachined bilayer unit of engineered tissues  
Methods and materials for making an apparatus which duplicates the functionality of a physiological system is provided.
8492135 Deformable transportable bioreactor chamber  
An apparatus and method is described for seeding and culturing cells on a sample. The apparatus includes a chamber in which the volume of the chamber may be adjusted without compromising the seal...
8486349 Microfluidic flow assay for measuring hemostatic phenotypes  
A microfluidic-based flow assay and methods of manufacturing the same are provided. Specifically, the microfluidic flow assay includes a micropatterned surface that induces clot formation and an...
8486631 Quality control methods for the manufacture of polymer arrays  
Described are quality control methods and devices for the reproducible manufacturing and integrity monitoring of polymers on electrochemical synthesis and detection chips. The devices and methods...
8486689 Microelectronic sensor device for the detection of target particles  
The invention relates to a microelectronic sensor device for the examination of target particles (1) that are bound to binding sites (3) at the binding surface (12) of a carrier (11). In a...
8486866 Method for the quantitative measurement of biomolecular targets deposited on a biochip, and device for implementing it  
The present invention relates in particular to a method for the quantitative measurement of biomolecular targets that have been deposited on a biochip (1) of the type with a matrix of probes...
8481261 Nucleic acid extraction method  
The present invention relates to a nucleic acid extracting apparatus, and the nucleic acid extracting apparatus can include a pipe-shaped tube having an open outlet at one side thereof, and a...
8481302 Total bacteria monitoring system  
A system for measuring total microbiological content in an aqueous medium by adding a fluorescent dye to the aqueous medium, measuring the fluorescent signal in the aqueous medium to obtain a...
8476015 Method for separating and detecting an analyte  
A method for separating and analyzing an analyte is provided which comprises, in a first position, transferring a liquid sample to a multiwell plate with a pipette tip, replacing the tips in the...
8476062 Biosensor method and system based on feature vector extraction  
A system for biosensor-based detection of toxins includes providing at least one time-dependent control signal generated by a biosensor in a gas or liquid medium, and obtaining a time-dependent...
8476063 Microfluidic devices  
Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various...
8476065 Device for measuring nanometer level pattern-dependent binding reactions  
The present invention is directed to a device comprising (a) a substrate having a surface and (b) an ordered array of posts over the surface, wherein the posts are capable of binding a protein or...
8476078 Cassette for sample preparation  
A cassette for preparing a sample is disclosed herein. The cassette includes a housing, which encloses the structures and the processes used to prepare the sample.
8470356 Tissue augmentation devices and methods  
Tissue augmentation devices, as well as methods of manufacturing and using the same, are disclosed. In certain embodiments, a tissue augmentation device comprises an elongate tissue penetrating...
8470586 Processing polynucleotide-containing samples  
Methods and systems for processing polynucleotides (e.g., DNA) are disclosed. A processing region includes one or more surfaces (e.g., particle surfaces) modified with ligands that regain...
8465972 Nanoparticulate cell culture surface  
A cell culture article including a substrate having nanoparticles on the substrate surface, the nanoparticle including: a polymer of formula (I) where (x), (y), (z), R, R′, R″, S, W, and X, are as...
8465967 Nanoparticle electrostatic trap  
A method of trapping a charged particle. The method includes providing a planar substrate having a conductive surface thereon, the conductive surface having at least one non-conductive region. The...
8460923 Affinity hydrogel and label independent detection methods thereof  
A biosensor article including a substrate having polymer modified surface, the polymer comprising the formula (I) where (x), (y), (z), R, R′, R″, S, W, and X, are as defined herein. Methods for...
8460744 Target activated microtransfer  
A device for performing target activated transfer that includes a mounting surface for mounting a tissue sample; and a light source positioned to substantially uniformly irradiate both stained and...
8460922 Immunosensor system for blood with reduced interference  
An electrochemical immunosensor system with reduced interference, comprising: a first immunosensor that generates an electrochemical signal based on the formation of a sandwich between an...
8455241 Culture observation system  
There is provided a culture observation system by which even a culture other than an observation target culture can be cultured and observation can be properly performed by a microscope during...
8449832 Reagent strip with removable tip  
A test sensor includes a base, a lid and a channel for receiving a fluid sample. The channel includes a reagent. The test sensor also includes a tip portion extending from at least one of the base...
8449833 Frustrated total internal reflection biosensor cartridge  
The present invention provides a biosensor cartridge (11) comprising a bottom portion (1) with a well (2) adapted to accommodate a liquid sample and a cover portion (3) for closing said well (2)....
8450101 Reaction chip, reaction method, temperature controlling unit for gene treating apparatus and gene treating apparatus  
The reaction chip of the present invention has a plurality of recesses 6 constituting a part of a reaction container and a groove constituting a part of a channel formed on at least one of one...
8450103 Method of derivatising an analyte for subsequent detection through a nucleic acid based sensor  
A method of derivatising an analyte for subsequent detection through a nucleic acid based sensor and a sensor based thereon.
8449825 High throughput screen  
The present invention relates to a structure comprising a biological membrane and a porous or perforated substrate, a biological membrane, a substrate, a high throughput screen, methods for...
8445262 Method for evaluating analyte  
In an analyte evaluation method for evaluating an analyte, AC voltage is applied between a substrate electrode on a substrate and a counter electrode, and signals obtained from a marker provided...
8440425 Method of preparing a biological specimen slide  
A method of preparing a slide of a biological specimen, including the steps of (a) providing a slide containing a biological specimen and a cover slip, (b) placing a liquid non-evaporating sealing...
8440470 Fabrication process of a biosensor on a semiconductor substrate  
The disclosure relates to a fabrication process of a biosensor on a semiconductor wafer, comprising steps of: making a central photosensitive zone comprising at least one pixel-type biological...
8440454 Pasting edge heater  
An apparatus and method for thermal cycling including a pasting edge heater. The pasting edge heater can provide substantial temperature uniformity throughout the retaining elements during thermal...