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6660232 |
Multi-well assay plate and plate holder and method of assembling the same
A multi-well plate and plate holder assembly comprising a multi-well assay plate clamped between an upper plate holder and a lower plate holder to facilitate handling of the plate, and to prevent...
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6653095 |
Hydrogen peroxide monitoring
A method and apparatus for determining the hydrogen peroxide content of a fluid. The method includes: (a) contacting the fluid with a catalyst so as to permit decomposition of the hydrogen peroxide...
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6649343 |
DNA chip and method for producing the same
A DNA chip includes a large number of minute spots formed by dripping sample solutions onto a base plate. The base plate is provided with positional deviation-correcting means for displacing the...
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6649384 |
System and method for encapsulating biological material by applying electrostatic charge to capsules
A method and system for the effective and consistent encapsulation of viable (i.e., living or physiologically active) biological material (preferably, pancreatic islets also known as islets of...
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6649348 |
Methods for manufacturing arrays
Apparatus and methods are disclosed for synthesizing a plurality of compounds on the surface of supports. Biopolymer features are attached to the surfaces of the supports. The synthesis generally...
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6645434 |
Sample observation plate and observation apparatus
A sample observation plate is provided which is smooth in a surface in molecular levels and cheap in price, thereby making feasible topological and optical observation in molecular levels. In a...
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6642016 |
Biosensor and its use to indicate the status of a product
A biosensor comprises a unit, comprising a substrate and an enzyme, which when brought into contact with the substrate is adapted to affect the substrate so that its conductivity changes as a...
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6635226 |
Microanalytical device and use thereof for conducting chemical processes
A microanalytical device is provided for conducting chemical processes using small amounts of fluid. The devices include microstructures, e.g., microcavities, microchannels and the like, that are...
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6632652 |
Reversibly sealable microstructure sorting devices
Methods and apparatus for sorting microstructures, such as macromolecules, viruses, cells, and minute particles, in a fluid using microlithographic sorting array that is reversibly sealed by a...
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6632662 |
Device and method for the lysis of micro-organisms
The invention concerns a device for lysis ( 1 ) of micro-organism to release at least one intracellular biological constituent, comprising a container ( 2 ) wherein are present a biological sample,...
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6632651 |
Tissue maintenance system that applies rhythmic pulses of pressure
A growth support scaffold for cells and tissue is formed of naturally derived connective or skeletal tissue which has been treated for elimination of cellular and cytosolic elements, and modified...
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6632629 |
Microfluidic in-line labeling method of continuous-flow protease inhibition analysis
Enzyme assays are performed in microfluidic devices including, e.g., in-line labeling, separation, and detection of assay products. In-line labeling allows assays, e.g., protease assays, to be...
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6630355 |
Magnetic focusing immunosensor for the detection of pathogens
A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and...
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6627410 |
Processing proteins from gels for analysis using mass spectrometry
The invention relates to methods and devices used for digesting small amounts of protein in tiny cut gel pieces and for extracting the peptides resulting from the digestion in preparation for...
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6623701 |
Specimen chamber for the liquid treatment of biological specimens
A specimen chamber ( 10 ) for the liquid treatment of at least one specimen ( 90 ) comprises a base plate ( 20 ) and a carrier plate ( 30 ), between which a gap-formed accommodation space is formed...
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6617153 |
Portable magneto-mechanical delivery device and method for delivery of reactive substances
A method of delivery of reactive substances that are attached to magnetizable needle-like particles using a magneto-mechanical delivery device. The subject method and device can be utilized for the...
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6617146 |
Method and apparatus for automatically inoculating culture media with bacterial specimens from specimen containers
A method and system are provided for automatically positioning specimen containers and culture medium containers and transferring specimen samples from the containers to the culture medium. The...
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6617151 |
Method of closing a cell containment device with a wet seal
A method is provided for closing a containment device that involves wetting at least a portion of a permeable polymeric membrane such as tubular membrane with a liquid such as a cell suspension or...
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6617152 |
Method for creating a cell growth surface on a polymeric substrate
A method, apparatus and product for producing an advantaged cell growth surface. According to the present invention, a stream of plasma is comprised of activated gaseous species generated by a...
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6613525 |
Microfluidic apparatus and method for purification and processing
Integrated microfluidic devices comprising at least an enrichment channel ( 10 ) and a main electrophoretic flowpath ( 12 ) are provided. In the subject integrated devices, the enrichment channel...
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6613542 |
Testing system for chemical substances or substance mixtures
In a testing system for chemical substances or substance mixtures, especially for potential plant protection compositions, the chemical substance to be tested or the substance mixture to be tested...
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6610528 |
Microbial enrichment using a container having a plurality of solid support particles
A method and device for collection and concentration of microbes via selectively attracting microbes to specific substrates chemically conjugated to a solid surface, such as a particle, are...
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6607917 |
Method of and apparatus for cultivating a cell or tissue
The invention provides a method of and an apparatus for cultivating a cell or tissue capable of preventing the cell or tissue from being contaminated and realizing an efficient in vitro culture....
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6605446 |
Detecting airborne microorganisms
A new apparatus and method for collecting and detecting airborne microorganisms comprises a culturing container containing liquid media capable of growing the suspect microorganisms and a pump for...
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6605438 |
Lyophilizing of liquid drops having arbitrary edges and application thereof to microarrays of biological reagents
The disclosure relates to the stabilization of a fluid drop comprising a liquid solvent and solute, so that upon drying of the solvent, the solute is not preferentially concentrated at the edges of...
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6602678 |
Non- or minimally invasive monitoring methods
An apparatus for sensing an analyte is described, wherein the apparatus includes an interface contact element that is used to establish an interface with a quantity of body fluid. The interface...
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6599712 |
Method and apparatus for measuring sample by luminescence
A method for measuring stains of a test sample by measuring adenosine phosphates. Luminescence of the adenosine phosphates is induced by a luminescent reagent ( 33 ) containing an ATP regenerating...
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6596507 |
Device and method for determining characteristic of a biomass
A device for determining the characteristics of a biomass, includes: a probe (S,S′) including electrodes, two or four in number, for injecting a current into a medium containing biological cells...
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6596505 |
Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms
The present invention relates to an apparatus and methods for testing the formation of biofilms on various materials. The apparatus includes a lid and a vessel, wherein the lid may be configured to...
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6593136 |
Culturing cells in a chamber in a stack of chambers
A chamber has a lid that permits opening and closing of the chamber for inserting or removing a cell culture from the chamber while the chamber is in a stack of chambers without removing any of the...
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RE38186 |
Method and apparatus for detecting microorganisms
A method for identifying a microorganism is described that includes abstracting gas or vapor associated with the microorganism from a detection region and flowing the same over an array of sensors...
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6593101 |
Enhancing contrast in biological imaging
Methods for enhancing contrast during imaging to assess cell and nuclear morphology of a sample. A contrast agent such as acetic acid, toluidine blue, hypertonic saline, hypotonic saline, Lugol's...
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6589761 |
Method and apparatus for detecting bacteria
A device and method for detecting bacteria in food substances and the like utilizing a three layer composite consisting of a transparent base, an indicator exhibiting color change when exposed to...
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6585939 |
Microstructures for use in biological assays and reactions
The present invention relates to microstructures which a fabricated from a cast or molded polymer material, such as polydimethylsiloxane (PDMS). The invention describes and claims methods and...
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6579712 |
System for reproducing and dispensing bio-cultures for bio-augmentation and method therefor
A system for reproducing and dispensing bio-cultures for bio-augmentation, and method therefor. The system comprises a bacteria solution breeding tank, a bacteria solution dispensing metering pump...
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6573087 |
Packaged timed release microorganisms and absorbent matrix for degradation of hydrocarbons
An absorbent package for containment and bioremediation of hydrocarbons and method thereof are disclosed. The package comprises a concentration of microorganisms, a timed release mechanism...
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6569671 |
Pattern exposure method, exposure device, formation of nucleic acid array, and formation of peptide array
This invention provides a pattern exposure method which may be used for effectively preparing, for example, a DNA or peptide array with a lower cost and a device therefor. Specifically, the method...
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6566126 |
Apparatus and method for growing cells
A cell-culture apparatus forms an extra-capillary space between at least one hollow fiber and an enclosed chamber. Cells are placed in the extra-capillary space to grow. A media reservoir holds a...
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6558897 |
Device for determining a substance contained in a body fluid
A device for determining a substance contained in a body fluid is provided. An indicator member has a testing zone that changes the color based on the concentration level of the substance contained...
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6558955 |
Methodology for predicting and/or diagnosing disease
Disorders are diagnosed by analyzing biological samples of ad libitum-fed and dietary-restricted individuals to generate frequency distribution patterns representative of molecular constituents of...
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6555074 |
Apparatus for making herbal extracts using percolation
The present invention comprises an apparatus and methods for making herbal extracts. The apparatus employs a percolation vessel having a filter and discharge valve. A heater is provided to heat the...
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6551784 |
Method of comparing nucleic acid sequences
The present invention provides methods for comparing and identifying differences in nucleic acid sequences using a plurality of sequence specific recognition reagents (i.e., probes comprising a...
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6548788 |
Devices and methods for using centripetal acceleration to drive fluid movement in a microfluidics system
This system provides methods and apparatus for performing microanalytic and microsynthetic analyses and procedures. Specifically, the system provides a microsystem platform for use with a...
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6544477 |
Apparatus for generating a temperature gradient
A novel apparatus for generating temperature gradients is described. The apparatus includes a semiconductive wafer and electrical connectors attached to, preferably, one of the edges of the wafer....
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6540895 |
Microfabricated cell sorter for chemical and biological materials
The invention provides a microfabricated device for sorting cells based on a desired characteristic, for example, reporter-labeled cells can be sorted by the presence or level of reporter on the...
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6540965 |
Biological analysis and apparatus for storage of biological samples
A microtitration plate including a plastic base having a multiplicity of cups shaped and sized to receive biological liquid samples, each cup being surrounded by an attenuated zone and having an...
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6541216 |
Amperometric biosensor test strip
A reagent and method for determining the levels of 3-hydroxybutyric acid in a sample are provided. The reagent comprises a ferricyanide salt, a catalytic amount of a first enzyme operative to...
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6541241 |
Method of using an apparatus containing a paddle for microenfractionating contaminated material
A method of using a paddle in the accelerated remediation of a contaminated material and a paddle, therefore, are provided. The method which comprises the steps of providing the paddle which is...
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6537772 |
Equipment, kit and method for microbiological diagnosis
The present invention is related to microbiology and forms part of a system for rapid microbiological diagnosis. The invention allows detection of turbidimetric changes due to microbial growth,...
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6534483 |
Protected one-vial formulation for nucleic acid molecules, methods of making the same by in-line mixing, and related products and methods
The present invention, as noted above, relates generally to the incorporation of plasmid into a conventional dosage form, and more particularly to the production of a single-vial, homogenized,...
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