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8609044 Vessel for performing microwave-assisted chemistry on small volumes of reagents  
A micro vial assembly for performing microwave-assisted chemical reactions on small reaction mixture volumes is disclosed, wherein a reaction vessel (10) is sealed through a diaphragm (30) that is...
8609043 Use of a container of an inorganic additive containing plastic material  
The present invention relates to the use of a container, made of an inorganic additive containing plastic material, for reducing physical/chemical interaction between the container and an oil, fat...
8603803 Solid phase electrochemical synthesis with controlled product cleavage  
Methods for electrochemically synthesizing polymers are provided in which a cleavable linker is coupled to the surface of at least one electrode of an array of electrodes on a substrate and a...
8597938 System for providing control reactions for real time RT-PCR  
Provided are methods and oligonucleotides useful as primers and templates for internal controls designed for use in Real Time Reverse Transcriptase Polymerase Chain Reactions. Use of the present...
8597882 Method and apparatus for conducting an assay  
The present invention relates to methods and apparatus for conducting nucleic acid sequencing by pyrosequencing. The method comprises the steps of providing a platform having at least one well for...
8597936 Device and method for the automated and reproducible production of cell or tissue samples that are to be analyzed and are arranged on object supports  
An automatically operating apparatus designed as a table-top apparatus for the reproducible production of cell or tissue samples to be examined and arranged on specimen slides comprises, located...
8592201 Chondrocyte container and method of use  
Devices and methods for delivering a therapeutic agent produced via a genetically-altered chondrocyte are provided. More specifically, the device includes a housing which defines a cell chamber...
8592225 Array-based bioactivated nanopore devices  
A nanopore device capable of single molecule detection is described. The nanopores are formed in thin, rigid membranes and modified by a sputtered metal that forms an overhang during application....
8592226 Surface-enhanced raman nanobiosensor  
The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides...
8586348 Lateral flow microfluidic assaying device and related method  
Provided herein is a microfluidic device and related method for controlling flow of different fluid components of a fluid. The microfluidic device comprises an input channel, focusing channel and...
8586347 System and method for detecting multiple molecules in one assay  
A rapid diagnostic system that delivers a panel of serologic assay results using a small amount of blood, serum, or plasma is described. The system includes a disposable cartridge and a reader...
8586350 Mechanism of separating and purifying DNA and the like  
A high-purity fragment is obtained by a simple mechanism and method for separating and purifying a nucleic acid, particularly fragment DNA, extremely efficiently and with a high reproducibility,...
8586337 Systems and methods for achieving partial nitrification in a biological nitrogen removal reactor  
Methods of controlling a nitrification reaction in a biological nitrogen removal reactor to favor partial nitrification of ammonia to nitrite instead of complete oxidation of ammonia to nitrate...
8580344 Stamp usage to enhance surface layer functionalization and selectivity  
This disclosure provides methods, devices and systems for using a stamp to enhance selectivity between surface layers of a substrate, and to facilitate functionalizing selected layers. An array of...
8580546 Micro-organ device  
A method for fabricating a micro-organ device comprises providing a microscale support having one or more microfluidic channels and one or more micro-chambers for housing a micro-organ and...
8574835 Scaffolded nucleic acid polymer particles and methods of making and using  
The invention provides particle compositions having applications in nucleic acid analysis. Nucleic acid polymer particles of the invention allow polynucleotides to be attached throughout their...
8574894 Molecular dispensers  
A molecular dispenser includes a molecular reservoir comprising a plurality of charged molecules; a nanopore proximate the molecular reservoir, the nanopore comprising a first set of locking...
8577621 Biopolymer array reading  
A method for processing biopolymer arrays and apparatus and computer program products for executing the method. The method may include reading a different array identifier for each biopolymer...
8574924 Assay device and method  
An assay method is described, which comprises the steps of immobilizing a binding partner (e.g., an antigen or antibody) for an analyte to be detected (e.g., an antibody or antigen) on a portion...
8574895 Method and apparatus using optical techniques to measure analyte levels  
A device is provided for use with a tissue penetrating system and/or a metering device for measuring analyte levels. The device comprises a cartridge and a plurality of analyte detecting members...
8574891 Nucleic acid analyzer, automatic analyzer, and analysis method  
This invention relates to a nucleic acid analyzer comprising: reaction containers capable of containing nucleic-acid-containing samples and reagents; an incubation mechanism capable of controlling...
8574892 Methods and apparatus for nucleic acid sequencing by signal stretching and data integration  
The methods and apparatus 100 disclosed herein concern DNA sequencing. In some embodiments of the invention, the methods comprise measuring the distance between labeled nucleotides 220, such as...
8569052 Oxygen depletion devices and methods for removing oxygen from red blood cells  
An oxygen depletion device. The device has a cartridge; a plurality of hollow fibers extending within the cartridge from an entrance to an exit thereof; an amount of an oxygen scavenger packed...
8569042 DNA structures on ferroelectrics and semiconductors  
An apparatus includes a substrate and a plurality of DNA oligomers in contact with a top surface of the substrate. The substrate is a polar ferroelectric or a polar compound semiconductor.
8569047 Microbial detection apparatus, microbial detection method, and sample container used therein  
The sample container has a two-layer membrane filter comprising a first layer as an upper layer serving as a hydrophilic membrane filter and a hydrophobic membrane filter as an underlying second...
8569072 Sample preparation container and method  
A system and method for preparing and delivering samples for analyte testing. The system can include a sample preparation system and a sample delivery system coupled to the sample preparation...
8569045 Water toxicity detecting apparatus and method using sulfur particles  
Provided are a water toxicity detecting apparatus and a method using sulfur particles. The water toxicity detecting apparatus using sulfur particles includes: a reaction container containing...
8563300 Incubator  
An incubator comprising: a culture chamber configured to accommodate culture; a dish structure configured to contain a liquid; an ultrasonic vibrator provided in a part of the dish structure, the...
8563297 Controllable binding and dissociation of chemical entities and electrode devices therefore  
Disclosed are methods for controlling molecular interactions where at least one member of a pair of chemical entities having a pH-dependent affinity is immobilized on the surface of an electrode....
8563320 Optical cell  
A use composition monitor determines the concentration of peracid and/or peroxide in a use composition using a kinetic assay procedure. A sample mixture containing a sample of the use composition,...
8563240 Nucleic acid sequencing and electronic detection  
Embodiments of the present invention provide devices methods for sequencing DNA using arrays of reaction regions containing sensors to monitor changes in solutions or bound molecules contained in...
8563237 Biopolymer resonant tunneling with a gate voltage source  
The invention provides an apparatus and method for sequencing and identifying a biopolymer. The invention provides a first electrode, a second electrode, a first gate electrode, a second gate...
8563253 Means and method for diagnosing hemolytic anemia  
The present invention relates to a method for diagnosing hemolytic anemia or a predisposition thereof. It also relates to a method of determining whether a compound is capable of inducing...
8557195 Sensor substrate and array substrate using the same  
A sensor substrate includes a base and fibrous projections on an upper surface of the base. The fibrous projections have fixed ends fixed to the upper surface of the base and free ends opposite to...
8557518 Microfluidic and nanofluidic devices, systems, and applications  
The present invention discloses the integration of programmable microfluidic circuits to achieve practical applications to process biochemical and chemical reactions and to integrate these...
8557568 Method and apparatus for disrupting cells and amplifying nucleic acids using gold nanorods  
Provided is a method of disrupting cells comprising adding gold nanorods to a solution containing cells and irradiating the gold nanorods with a laser to disrupt the cells. A method and an...
8551760 Substrate for immobilizing biopolymer and method of immobilizing biopolymer by using the same  
[Problems] To immobilize a chain-type biopolymer in an elongated state at a predetermined position on a substrate. [Means for Solving Problems] A substrate (1) for immobilizing a biopolymer, which...
8551738 Systems and methods for rapid identification of nucleic acid variants  
There is a need for nucleic acid analysis which is both specific and rapid, and in which no nucleic acid sequencing is required. The present invention addresses this need, among others by...
8551759 Oligomer probe array and method of producing the same  
An oligomer probe array having improved reaction yield is provided. The oligomer probe array includes a substrate, an immobilization layer on the substrate, a plurality of nano particles coupled...
8551767 Sensor for detection of nucleic acid  
A sensor for detection of target nucleic acid comprising (a) a semiconductor nanostructure; and (b) a nucleic acid detection probe immobilized on the semiconductor nanostructure capable of...
8551761 Cartridge and device for analyzing biological samples using temperature-controlled biological reactions  
The cartridge according to the invention for analysing biological samples comprises: a reaction chamber and a biochip mounted in the reaction chamber,a filling nozzle connected so as to...
8546127 Bacteria/RNA extraction device  
Apparatus and method for collection of a target material from a liquid sample comprising target species that contain the target material. The apparatus comprises a fluid flow conduit in...
8545760 Specimen analyzing method and specimen analyzing apparatus  
A specimen analyzing method and a specimen analyzing apparatus capable of measuring interference substances before analyzing a specimen. The method comprises a step for sucking the specimen stored...
8546128 Fluidics system for sequential delivery of reagents  
The invention provides a passive fluidics circuit for directing different fluids to a common volume, such as a reaction chamber or flow cell, without intermixing or cross contamination. The...
8546129 Sample analysis chip, sample analyzer using sample analysis chip, sample analysis method, and method of producing sample analysis chip  
A low cost sample analysis chip in which liquid is supplied to wells formed on the chip so as to carry out reaction by a simple liquid supply method with no variation in the amount of liquid in...
8541005 Cysteine-tagged streptococcal protein G variant  
The present invention relates to an N-terminal cysteine-tagged Streptococcal protein G variant. Since the variant binds in a directional manner to a surface of a biochip or a biosensor, the...
8541217 Cytoblock preparation system and methods of use  
An apparatus and method that may be used for collecting target cells or tissue and preparing a cell block are disclosed.
8541015 Three-dimensional biological scaffold and method of making the same  
A three-dimensional biological scaffold. The scaffold includes at least three sets of polymer waveguides extending along at least three respective directions. The at least three sets of polymer...
8535949 Water relaxation-based sensors  
This invention relates to magnetic resonance-based sensors and related methods.
8535876 Laser-micro-dissection method and device for laser-micro-dissection  
A laser-micro-dissection method and a device for laser micro-dissection involves cutting a dissectate from a biological sample, which is applied to a planar carrier, by means of laser pulses along...